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Abstract 2616: Stemness factors nanog and oct4 contribute to epithelial-to-mesenchymal transition and are predictive for outcome in esophageal adenocarcinoma

Amber Perenna van der Zalm, Mark P. Dings, Reimer Janssen, Peter Bailey, Jan Koster, Danny Zwijnenburg, Richard Volckmann, Cynthia Waasdorp, Jeroen Blokhuis, César Oyarce, Gerrit Hooijer, Sybren L. Meijer, Jan Paul Medema, Hanneke W. van Laarhoven, Maarten F. Bijlsma

Cancer Res (2022) 82 (12_Supplement): 2616.

https://doi.org/10.1158/1538-7445.AM2022-2616

Published: 15 June 2022

View articletitled, Abstract 2616: Stemness factors nanog and oct4 contribute to epithelial-to-mesenchymal transition and are predictive for outcome in esophageal adenocarcinoma

Journal Articles

Abstract 4008: Transcriptomic signatures in esophageal adenocarcinoma define distinct subtypes with therapeutic relevance

Mark P.G. Dings, Amber P. Zalm, Marjolein F. Lansbergen, César Oyarce, Sybren L. Meijer, Cynthia Waasdorp, Jan Paul Medema, Hanneke van Laarhoven, Maarten F. Bijlsma

Cancer Res (2022) 82 (12_Supplement): 4008.

https://doi.org/10.1158/1538-7445.AM2022-4008

Published: 15 June 2022

View articletitled, Abstract 4008: Transcriptomic signatures in esophageal adenocarcinoma define distinct subtypes with therapeutic relevance

Journal Articles

Abstract 5163: A colon cancer survivor-derived antibody recognizes a previously unidentified truncated, O-mannosylated 70kDa variant of E-cadherin

Cancer Res (2020) 80 (16_Supplement): 5163.

https://doi.org/10.1158/1538-7445.AM2020-5163

Published: 15 August 2020

View articletitled, Abstract 5163: A colon cancer survivor-derived antibody recognizes a previously unidentified truncated, O-mannosylated 70kDa variant of E-cadherin

Journal Articles

Abstract 2645: Development of a first in class APRIL fully blocking antibody BION-1301 for the treatment of multiple myeloma

John Dulos, Lilian Driessen, Marc Snippert, Marco Guadagnoli, Astrid Bertens, David Lutje Hulsik, Tai Yu Tzu, Kenneth Anderson, Jan Paul Medema, Kate Cameron, Hans Eenennaam, Andrea Elsas

Cancer Res (2017) 77 (13_Supplement): 2645.

https://doi.org/10.1158/1538-7445.AM2017-2645

Published: 01 July 2017

View articletitled, Abstract 2645: Development of a first in class APRIL fully blocking antibody BION-1301 for the treatment of multiple myeloma

Journal Articles

Prostate Cancer Patients with Late Radiation Toxicity Exhibit Reduced Expression of Genes Involved in DNA Double-Strand Break Repair and Homologous Recombination

Bregje van Oorschot, Lon Uitterhoeve, Ilja Oomen, Rosemarie ten Cate, Jan Paul Medema, Harry Vrieling, Lukas J.A. Stalpers, Perry D. Moerland, Nicolaas A.P. Franken

Cancer Res (2017) 77 (6): 1485–1491.

https://doi.org/10.1158/0008-5472.CAN-16-1966

Published: 14 March 2017

View articletitled, Prostate Cancer Patients with Late Radiation Toxicity Exhibit Reduced Expression of Genes Involved in DNA Double-Strand Break Repair and Homologous Recombination

Includes: Supplementary data

Journal Articles

Abstract 3193: Development of a colon cancer model system reveals epithelial contribution to poor-prognosis gene signatures

Pramudita R. Prasetyanti, Sander R. van Hooff, Hans M. Rodermond, Tessa van Herwaarden, Kieshen Kalloe, Nathalie R. de Vries, Ronals van Leersum, Joan H. de jong, Evelyn Fessler, Nicolo Baldi, Giorgio Stassi, Jan Paul Medema

Cancer Res (2016) 76 (14_Supplement): 3193.

https://doi.org/10.1158/1538-7445.AM2016-3193

Published: 15 July 2016

View articletitled, Abstract 3193: Development of a colon cancer model system reveals epithelial contribution to poor-prognosis gene signatures

Journal Articles

Abstract 3125: KCNQ1 expression is a strong prognostic biomarker for disease recurrence in stage II and III colon cancer

Sjoerd H. den Uil, Veerle M.H. Coupe, Janneke F. Linnekamp, Evert van den Broek, Jeroen A.C.M. Goos, Pien M. Delis-van Diemen, Eric J.T. Belt, Nicole C.T. van Grieken, Patricia M. Scott, Louis Vermeulen, Jan Paul Medema, Herman Bril, Hein B.A.C. Stockmann, Robert T. Cormier, Gerrit A. Meijer, Remond J. Fijneman

Cancer Res (2016) 76 (14_Supplement): 3125.

https://doi.org/10.1158/1538-7445.AM2016-3125

Published: 15 July 2016

View articletitled, Abstract 3125: KCNQ1 expression is a strong prognostic biomarker for disease recurrence in stage II and III colon cancer

Journal Articles

Hyperthermia Selectively Targets Human Papillomavirus in Cervical Tumors via p53-Dependent Apoptosis

Arlene L. Oei, Caspar M. van Leeuwen, Rosemarie ten Cate, Hans M. Rodermond, Marrije R. Buist, Lukas J.A. Stalpers, Johannes Crezee, H. Petra Kok, Jan Paul Medema, Nicolaas A.P. Franken

Cancer Res (2015) 75 (23): 5120–5129.

https://doi.org/10.1158/0008-5472.CAN-15-0816

Published: 30 November 2015

View articletitled, Hyperthermia Selectively Targets Human Papillomavirus in Cervical Tumors via p53-Dependent Apoptosis

Includes: Supplementary data

Journal Articles

Abstract 421: The role of the tumor microenvironment of pancreatic cancer to predict treatment outcome

Anne Steins, Remy Klaassen, Oliver Gurney-Champion, Maarten Bijlsma, Jan Paul Medema, Hessel Wijkstra, Geertjan van Tienhoven, Olivier Busch, Cornelis Punt, Marc Besselink, Hanneke Wilmink, Marc van de Vijver, Jaap Stoker, Aart Nederveen, Hanneke van Laarhoven

Cancer Res (2015) 75 (15_Supplement): 421.

https://doi.org/10.1158/1538-7445.AM2015-421

Published: 01 August 2015

View articletitled, Abstract 421: The role of the tumor microenvironment of pancreatic cancer to predict treatment outcome

Journal Articles

Abstract LB-143: DNp63 governs metastatic outgrowth of breast cancer stem cells

Alice Turdo, Simone Di Franco, Antonina Benfante, Maria Luisa Colorito, Marco Bonanno, Miriam Gaggianesi, Daniela Barcaroli, Francesco Dieli, Jan Paul Medema, Vincenzo De Laurenzi, Giorgio Stassi, Matilde Todaro

Cancer Res (2015) 75 (15_Supplement): LB-143.

https://doi.org/10.1158/1538-7445.AM2015-LB-143

Published: 01 August 2015

View articletitled, Abstract LB-143: DNp63 governs metastatic outgrowth of breast cancer stem cells

Journal Articles

Abstract 5177: Heterogeneity of pancreatic ductal adenocarcinoma visualized

Veronique Veenstra, Helene Damhofer, Tom van Leusden, Jan Kessler, Jan Paul Medema, Hanneke van Laarhoven, Louis Vermeulen, Maarten Bijlsma

Cancer Res (2015) 75 (15_Supplement): 5177.

https://doi.org/10.1158/1538-7445.AM2015-5177

Published: 01 August 2015

View articletitled, Abstract 5177: Heterogeneity of pancreatic ductal adenocarcinoma visualized

Journal Articles

Abstract 5273: Role of methylation of Wnt target genes in tumorigenesis and effect of re-expression with demethylating agent decitabine in colon cancer

Janneke Linnekamp, Raju Kandimalla, Louis Vermeulen, Hanneke van Laarhoven, Jan Paul Medema

Cancer Res (2015) 75 (15_Supplement): 5273.

https://doi.org/10.1158/1538-7445.AM2015-5273

Published: 01 August 2015

View articletitled, Abstract 5273: Role of methylation of Wnt target genes in tumorigenesis and effect of re-expression with demethylating agent decitabine in colon cancer

Journal Articles

Abstract LB-108: Automated immunohistochemistry-based identification of molecular subtypes in colorectal cancer

Anne Trinh, Filipe De Sousa E Melo, Xin Wang, Joan H de Jong, Evelyn Fessler, Marnix Jansen, Gerrit KJ Hooijer, Jan Paul Medema, Florian Markowetz, Louis Vermeulen

Cancer Res (2015) 75 (15_Supplement): LB-108.

https://doi.org/10.1158/1538-7445.AM2015-LB-108

Published: 01 August 2015

View articletitled, Abstract LB-108: Automated immunohistochemistry-based identification of molecular subtypes in colorectal cancer

Journal Articles

Abstract 350: HER3 mediates acquired resistance to HER2-targeted therapy in esophageal adenocarcinoma

Eva A. Ebbing, Jan Paul Medema, Sybren L. Meijer, Kausilia K. Krishnadath, Mark I. van Berge Henegouwen, Maarten F. Bijlsma, Hanneke W. M. van Laarhoven

Cancer Res (2015) 75 (15_Supplement): 350.

https://doi.org/10.1158/1538-7445.AM2015-350

Published: 01 August 2015

View articletitled, Abstract 350: HER3 mediates acquired resistance to HER2-targeted therapy in esophageal adenocarcinoma

Journal Articles

Colorectal Cancer Heterogeneity and Targeted Therapy: A Case for Molecular Disease Subtypes

Janneke F. Linnekamp, Xin Wang, Jan Paul Medema, Louis Vermeulen

Cancer Res (2015) 75 (2): 245–249.

https://doi.org/10.1158/0008-5472.CAN-14-2240

Published: 14 January 2015

View articletitled, Colorectal Cancer Heterogeneity and Targeted Therapy: A Case for Molecular Disease Subtypes

Journal Articles

Abstract B71: Elucidation of the stromal contribution to sonic hedgehog-dependent pancreatic adenocarcinoma.

Helene Damhofer, Maarten F. Bijlsma, Jan Paul Medema

Cancer Res (2012) 72 (14_Supplement): B71.

https://doi.org/10.1158/1538-7445.PANCA2012-B71

Published: 03 April 2014

View articletitled, Abstract B71: Elucidation of the stromal contribution to sonic hedgehog-dependent pancreatic adenocarcinoma.

Journal Articles

Abstract 5480: Characterization of anti-human APRIL monoclonal antibodies capable of inhibiting APRIL-dependent B cell function and hyperproliferation.

Marco Guadagnoli, Katherine Cameron, Elise Veraar, Fiona Kimberley, Andrea van Elsas, Hans van Eenennaam, Jan Paul Medema

Cancer Res (2013) 73 (8_Supplement): 5480.

https://doi.org/10.1158/1538-7445.AM2013-5480

Published: 15 April 2013

View articletitled, Abstract 5480: Characterization of anti-human APRIL monoclonal antibodies capable of inhibiting APRIL-dependent B cell function and hyperproliferation.

Journal Articles

Cancer Stem Cell Niche: The Place to Be

Tijana Borovski, Felipe De Sousa E Melo, Louis Vermeulen, Jan Paul Medema

Cancer Res (2011) 71 (3): 634–639.

https://doi.org/10.1158/0008-5472.CAN-10-3220

Published: 01 February 2011

View articletitled, Cancer Stem Cell Niche: The Place to Be

Journal Articles

Abstract 1200: Oncogenic KRAS sensitizes colorectal tumor cells to chemotherapy via p53-dependent induction of Noxa

Menno T. de Bruijn, Daniëlle A. Raats, Frederik J. Hoogwater, Winan J. van Houdt, Kate Cameron, Jan-Paul Medema, Inne H. Borel Rinkes, Onno Kranenburg

Cancer Res (2010) 70 (8_Supplement): 1200.

https://doi.org/10.1158/1538-7445.AM10-1200

Published: 15 April 2010

View articletitled, Abstract 1200: Oncogenic KRAS sensitizes colorectal tumor cells to chemotherapy via p53-dependent induction of Noxa

Journal Articles

The AC133 Epitope, but not the CD133 Protein, Is Lost upon Cancer Stem Cell Differentiation

Kristel Kemper, Martin R. Sprick, Martijn de Bree, Alessandro Scopelliti, Louis Vermeulen, Maarten Hoek, Jurrit Zeilstra, Steven T. Pals, Huseyin Mehmet, Giorgio Stassi, Jan Paul Medema

Cancer Res (2010) 70 (2): 719–729.

https://doi.org/10.1158/0008-5472.CAN-09-1820

Published: 13 January 2010

View articletitled, The AC133 Epitope, but not the CD133 Protein, Is Lost upon Cancer Stem Cell Differentiation

Includes: Supplementary data

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Abstract 2616: Stemness factors nanog and oct4 contribute to epithelial-to-mesenchymal transition and are predictive for outcome in esophageal adenocarcinoma

Abstract 4008: Transcriptomic signatures in esophageal adenocarcinoma define distinct subtypes with therapeutic relevance

Abstract 5163: A colon cancer survivor-derived antibody recognizes a previously unidentified truncated, O-mannosylated 70kDa variant of E-cadherin

Abstract 2645: Development of a first in class APRIL fully blocking antibody BION-1301 for the treatment of multiple myeloma

Prostate Cancer Patients with Late Radiation Toxicity Exhibit Reduced Expression of Genes Involved in DNA Double-Strand Break Repair and Homologous Recombination

Abstract 3193: Development of a colon cancer model system reveals epithelial contribution to poor-prognosis gene signatures

Abstract 3125: KCNQ1 expression is a strong prognostic biomarker for disease recurrence in stage II and III colon cancer

Hyperthermia Selectively Targets Human Papillomavirus in Cervical Tumors via p53-Dependent Apoptosis

Abstract 421: The role of the tumor microenvironment of pancreatic cancer to predict treatment outcome

Abstract LB-143: DNp63 governs metastatic outgrowth of breast cancer stem cells

Abstract 5177: Heterogeneity of pancreatic ductal adenocarcinoma visualized

Abstract 5273: Role of methylation of Wnt target genes in tumorigenesis and effect of re-expression with demethylating agent decitabine in colon cancer

Abstract LB-108: Automated immunohistochemistry-based identification of molecular subtypes in colorectal cancer

Abstract 350: HER3 mediates acquired resistance to HER2-targeted therapy in esophageal adenocarcinoma

Colorectal Cancer Heterogeneity and Targeted Therapy: A Case for Molecular Disease Subtypes

Abstract B71: Elucidation of the stromal contribution to sonic hedgehog-dependent pancreatic adenocarcinoma.

Abstract 5480: Characterization of anti-human APRIL monoclonal antibodies capable of inhibiting APRIL-dependent B cell function and hyperproliferation.

Cancer Stem Cell Niche: The Place to Be

Abstract 1200: Oncogenic KRAS sensitizes colorectal tumor cells to chemotherapy via p53-dependent induction of Noxa

The AC133 Epitope, but not the CD133 Protein, Is Lost upon Cancer Stem Cell Differentiation

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