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Jan G. M. Klijn
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Journal Articles

How ADAM-9 and ADAM-11 differentially from estrogen-receptor predict response to tamoxifen treatment in patients with recurrent breast cancer: A retrospective study

Anieta M. Sieuwerts, Marion E. Meijer-Van Gelder, Mieke Timmermans, Anita M. A. C. Trapman, Roberto Rodrigues Garcia, Miranda Arnold, Anneke W. Goedheer, Henk Portengen, Els M. J. J. Berns, Jan G. M. Klijn, John A. Foekens
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 501.
Published: 01 May 2005
View articletitled, How ADAM-9 and ADAM-11 differentially from estrogen-receptor predict response to tamoxifen treatment in patients with recurrent breast cancer: A retrospective study
Journal Articles

DNA-hypermethylation of PITX2 and risk of breast cancer recurrence in lymph node-negative hormone receptor-positive breast cancer patients

John W. M. Martens, Sabine Maier, Ina Schwope, Thomas Koenig, Oliver Hartmann, Antje Kluth, Maxime P. Look, Nadia Harbeck, Joan Bolt-De Vries, Anieta M. Sieuwerts, Henk Portengen, Marion E. Meijer-Van Gelder, Manfred Schmitt, Jan G. M. Klijn, John A. Foekens, Inko Nimmrich
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 650.
Published: 01 May 2005
View articletitled, DNA-hypermethylation of PITX2 and risk of breast cancer recurrence in lymph node-negative hormone receptor-positive breast cancer patients
Journal Articles

Urokinase-Type Plasminogen Activator System in Breast Cancer: Association with Tamoxifen Therapy in Recurrent Disease

Marion E. Meijer-van Gelder, Maxime P. Look, Harry A. Peters, Manfred Schmitt, Nils Brünner, Nadia Harbeck, Jan G. M. Klijn, John A. Foekens
Journal: Cancer Research
Cancer Res (2004) 64 (13): 4563–4568.
https://doi.org/10.1158/0008-5472.CAN-03-3848
Published: 01 July 2004
View articletitled, Urokinase-Type Plasminogen Activator System in Breast Cancer: Association with Tamoxifen Therapy in Recurrent Disease
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Journal Articles

Are ATM Mutations 7271T→G and IVS10-6T→G Really High-Risk Breast Cancer-Susceptibility Alleles?

Csilla I. Szabo, Mieke Schutte, Annegien Broeks, Jeanine J. Houwing-Duistermaat, Yvonne R. Thorstenson, Francine Durocher, Rogier A. Oldenburg, Marijke Wasielewski, Fabrice Odefrey, Deborah Thompson, Arno N. Floore, Jaennelle Kraan, Jan G. M. Klijn, Ans M. W. van den Ouweland, the BRCA-X Consortium, Cooperative Family Registry Breast Cancer Study, Interdisciplinary Health Research International Team on Breast Cancer Susceptibility, Teresa M. U. Wagner, Peter Devilee, Jacques Simard, Laura J. van ‘t Veer, David E. Goldgar, Hanne Meijers-Heijboer
Journal: Cancer Research
Cancer Res (2004) 64 (3): 840–843.
https://doi.org/10.1158/0008-5472.CAN-03-2678
Published: 10 February 2004
View articletitled, Are ATM Mutations 7271T→G and IVS10-6T→G Really High-Risk Breast Cancer-Susceptibility Alleles?
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Journal Articles

The CHEK2*1100delC Variant Acts as a Breast Cancer Risk Modifier in Non-BRCA1/BRCA2 Multiple-Case Families

Rogier A. Oldenburg, Karin Kroeze-Jansema, Jaennelle Kraan, Hans Morreau, Jan G. M. Klijn, Nicoline Hoogerbrugge, Marjolein J. L. Ligtenberg, Christi J. van Asperen, Hans F. A. Vasen, Carel Meijers, Hanne Meijers-Heijboer, Truuske H. de Bock, Cees J. Cornelisse, Peter Devilee
Journal: Cancer Research
Cancer Res (2003) 63 (23): 8153–8157.
Published: 16 December 2003
View articletitled, The CHEK2*1100delC Variant Acts as a Breast Cancer Risk Modifier in Non-BRCA1/BRCA2 Multiple-Case Families
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Journal Articles

The Prognostic Value of Polymorphonuclear Leukocyte Elastase in Patients with Primary Breast Cancer

John A. Foekens, Christian Ries, Maxime P. Look, Cornelia Gippner-Steppert, Jan G. M. Klijn, Marianne Jochum
Journal: Cancer Research
Cancer Res (2003) 63 (2): 337–341.
Published: 15 January 2003
View articletitled, The Prognostic Value of Polymorphonuclear Leukocyte Elastase in Patients with Primary Breast Cancer
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Journal Articles

Enhanced Benefit from Adjuvant Chemotherapy in Breast Cancer Patients Classified High-Risk according to Urokinase-type Plasminogen Activator (uPA) and Plasminogen Activator Inhibitor Type 1 ( n = 3424)

Nadia Harbeck, Ronald E. Kates, Maxime P. Look, Marion E. Meijer-van Gelder, Jan G. M. Klijn, Achim Krüger, Marion Kiechle, Fritz Jänicke, Manfred Schmitt, John A. Foekens
Journal: Cancer Research
Cancer Res (2002) 62 (16): 4617–4622.
Published: 15 August 2002
View articletitled, Enhanced Benefit from Adjuvant Chemotherapy in Breast Cancer Patients Classified High-Risk according to Urokinase-type Plasminogen Activator (uPA) and Plasminogen Activator Inhibitor Type 1 ( n = 3424)
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Journal Articles

High Tumor Levels of Vascular Endothelial Growth Factor Predict Poor Response to Systemic Therapy in Advanced Breast Cancer

John A. Foekens, Harry A. Peters, Nicolai Grebenchtchikov, Maxime P. Look, Marion E. Meijer-van Gelder, Anneke Geurts-Moespot, Theo H. van der Kwast, C. G. J. (Fred) Sweep, Jan G. M. Klijn
Journal: Cancer Research
Cancer Res (2001) 61 (14): 5407–5414.
Published: 01 July 2001
View articletitled, High Tumor Levels of Vascular Endothelial Growth Factor Predict Poor Response to Systemic Therapy in Advanced Breast Cancer
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Journal Articles

Thymidine Kinase and Thymidylate Synthase in Advanced Breast Cancer: Response to Tamoxifen and Chemotherapy

John A. Foekens, Sylvie Romain, Maxime P. Look, Pierre-Marie Martin, Jan G. M. Klijn
Journal: Cancer Research
Cancer Res (2001) 61 (4): 1421–1425.
Published: 02 February 2001
View articletitled, Thymidine Kinase and Thymidylate Synthase in Advanced Breast Cancer: Response to Tamoxifen and Chemotherapy
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Journal Articles

Mutant E-cadherin Breast Cancer Cells Do Not Display Constitutive Wnt Signaling

Marc van de Wetering, Nick Barker, I. Clara Harkes, Marcel van der Heyden, Nicolette J. Dijk, Antoinette Hollestelle, Jan G. M. Klijn, Hans Clevers, Mieke Schutte
Journal: Cancer Research
Cancer Res (2001) 61 (1): 278–284.
Published: 01 January 2001
View articletitled, Mutant E-cadherin Breast Cancer Cells Do Not Display Constitutive Wnt Signaling
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Journal Articles

Complete Sequencing of TP53 Predicts Poor Response to Systemic Therapy of Advanced Breast Cancer

Els M. J. J. Berns, John A. Foekens, Rolf Vossen, Maxime P. Look, Peter Devilee, Sonja C. Henzen-Logmans, Iris L. van Staveren, Wim L. J. van Putten, Mats Inganäs, Marion E. Meijer-van Gelder, Cees Cornelisse, Cassandra J. C. Claassen, Henk Portengen, Bert Bakker, Jan G. M. Klijn
Journal: Cancer Research
Cancer Res (2000) 60 (8): 2155–2162.
Published: 01 April 2000
View articletitled, Complete Sequencing of TP53 Predicts Poor Response to Systemic Therapy of Advanced Breast Cancer
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Journal Articles

The Urokinase System of Plasminogen Activation and Prognosis in 2780 Breast Cancer Patients

John A. Foekens, Harry A. Peters, Maxime P. Look, Henk Portengen, Manfred Schmitt, Michael D. Kramer, Nils Brünner, Fritz Jänicke, Marion E. Meijer-van Gelder, Sonja C. Henzen-Logmans, Wim L. J. van Putten, Jan G. M. Klijn
Journal: Cancer Research
Cancer Res (2000) 60 (3): 636–643.
Published: 01 February 2000
View articletitled, The Urokinase System of Plasminogen Activation and Prognosis in 2780 Breast Cancer Patients
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Journal Articles

Prognostic Value of Urokinase-type Plasminogen Activator in 671 Primary Breast Cancer Patients

John A. Foekens, Manfred Schmitt, Wim L. J. van Putten, Harry A. Peters, Marijke Bontenbal, Fritz Jänicke, Jan G. M. Klijn
Journal: Cancer Research
Cancer Res (1992) 52 (21): 6101–6105.
Published: 01 November 1992
View articletitled, Prognostic Value of Urokinase-type Plasminogen Activator in 671 Primary Breast Cancer Patients
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Journal Articles

c-myc Amplification Is a Better Prognostic Factor than HER2/neu Amplification in Primary Breast Cancer

Els M. J. J. Berns, Jan G. M. Klijn, Wim L. J. van Putten, Iris L. van Staveren, Henk Portengen, John A. Foekens
Journal: Cancer Research
Cancer Res (1992) 52 (5): 1107–1113.
Published: 01 March 1992
View articletitled, c-myc Amplification Is a Better Prognostic Factor than HER2/neu Amplification in Primary Breast Cancer
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Journal Articles

Sporadic Amplification of the Insulin-like Growth Factor 1 Receptor Gene in Human Breast Tumors

Els M. J. J. Berns, Jan G. M. Klijn, Iris L. van Staveren, Henk Portengen, John A. Foekens
Journal: Cancer Research
Cancer Res (1992) 52 (4): 1036–1039.
Published: 01 February 1992
View articletitled, Sporadic Amplification of the Insulin-like Growth Factor 1 Receptor Gene in Human Breast Tumors
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Journal Articles

Prediction of Relapse and Survival in Breast Cancer Patients by pS2 Protein Status

John A. Foekens, Marie-Christine Rio, Patrick Seguin, Wim L. J. van Putten, Joël Fauque, Marius Nap, Jan G. M. Klijn, Pierre Chambon
Journal: Cancer Research
Cancer Res (1990) 50 (13): 3832–3837.
Published: 01 July 1990
View articletitled, Prediction of Relapse and Survival in Breast Cancer Patients by pS2 Protein Status
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Journal Articles

Prognostic Value of Receptors for Insulin-like Growth Factor 1, Somatostatin, and Epidermal Growth Factor in Human Breast Cancer

John A. Foekens, Henk Portengen, Wim L. J. van Putten, Anita M. A. C. Trapman, Jean-Claude Reubi, Jana Alexieva-Figusch, Jan G. M. Klijn
Journal: Cancer Research
Cancer Res (1989) 49 (24_Part_1): 7002–7009.
Published: 15 December 1989
View articletitled, Prognostic Value of Receptors for Insulin-like Growth Factor 1, Somatostatin, and Epidermal Growth Factor in Human Breast Cancer
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Journal Articles

Prognostic Value of Estrogen and Progesterone Receptors Measured by Enzyme Immunoassays in Human Breast Tumor Cytosols

John A. Foekens, Henk Portengen, Wim L. J. van Putten, Harry A. Peters, Hendrik L. J. M. Krijnen, Jana Alexieva-Figusch, Jan G. M. Klijn
Journal: Cancer Research
Cancer Res (1989) 49 (21): 5823–5828.
Published: 01 November 1989
View articletitled, Prognostic Value of Estrogen and Progesterone Receptors Measured by Enzyme Immunoassays in Human Breast Tumor Cytosols
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Journal Articles

Antiprogestins, a New Form of Endocrine Therapy for Human Breast Cancer

Jan G. M. Klijn, Frank H. de Jong, Ger H. Bakker, Steven W. J. Lamberts, Cees J. Rodenburg, Jana Alexieva-Figusch
Journal: Cancer Research
Cancer Res (1989) 49 (11): 2851–2856.
Published: 01 June 1989
View articletitled, Antiprogestins, a New Form of Endocrine Therapy for Human Breast Cancer
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Journal Articles

Direct Inhibitory Effects of Somatostatin (Analogues) on the Growth of Human Breast Cancer Cells

Buddy Setyono-Han, Marcel S. Henkelman, John A. Foekens, Jan G. M. Klijn
Journal: Cancer Research
Cancer Res (1987) 47 (6): 1566–1570.
Published: 01 March 1987
View articletitled, Direct Inhibitory Effects of Somatostatin (Analogues) on the Growth of Human Breast Cancer Cells
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