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Jan G. Hengstler
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Journal Articles

Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer

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Jörn Weisner, Ina Landel, Christoph Reintjes, Niklas Uhlenbrock, Marija Trajkovic-Arsic, Niklas Dienstbier, Julia Hardick, Swetlana Ladigan, Marius Lindemann, Steven Smith, Lena Quambusch, Rebekka Scheinpflug, Laura Depta, Rajesh Gontla, Anke Unger, Heiko Müller, Matthias Baumann, Carsten Schultz-Fademrecht, Georgia Günther, Abdelouahid Maghnouj, Matthias P. Müller, Michael Pohl, Christian Teschendorf, Heiner Wolters, Richard Viebahn, Andrea Tannapfel, Waldemar Uhl, Jan G. Hengstler, Stephan A. Hahn, Jens T. Siveke, Daniel Rauh
Journal: Cancer Research
Cancer Res (2019) 79 (9): 2367–2378.
https://doi.org/10.1158/0008-5472.CAN-18-2861
Published: 01 May 2019
View articletitled, Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Glycerol-3-phosphate Acyltransferase 1 Promotes Tumor Cell Migration and Poor Survival in Ovarian Carcinoma

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Rosemarie Marchan, Bettina Büttner, Jörg Lambert, Karolina Edlund, Iris Glaeser, Meinolf Blaszkewicz, Gregor Leonhardt, Lisa Marienhoff, Darius Kaszta, Moritz Anft, Carsten Watzl, Katrin Madjar, Marianna Grinberg, Eugen Rempel, Roland Hergenröder, Silvia Selinski, Jörg Rahnenführer, Michaela S. Lesjak, Joanna D. Stewart, Cristina Cadenas, Jan G. Hengstler
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (17): 4589–4601.
https://doi.org/10.1158/0008-5472.CAN-16-2065
Published: 31 August 2017
View articletitled, Glycerol-3-phosphate Acyltransferase 1 Promotes Tumor Cell Migration and Poor Survival in Ovarian Carcinoma
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Includes: Supplementary data
Journal Articles

Abstract P6-08-20: Prognostic significance of the interferon metagene in node-negative breast cancer depends on the molecular subtype

Free
Marcus Schmidt, Leonie van de Sandt, Karolina Edlund, Isabel Sicking, Marco Battista, Anne-Sophie Heimes, Antje Lebrecht, Gerald Hoffmann, Mathias Gehrmann, Jörg Rahnenführer, Jan G Hengstler
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P6-08-20.
https://doi.org/10.1158/1538-7445.SABCS14-P6-08-20
Published: 01 May 2015
View articletitled, Abstract P6-08-20: Prognostic significance of the interferon metagene in node-negative breast cancer depends on the molecular subtype
Journal Articles

Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Free
Jae Ho Lee, Cornelia Jung, Parisa Javadian-Elyaderani, Stefan Schweyer, Dorothea Schütte, Moneef Shoukier, Feridoun Karimi-Busheri, Michael Weinfeld, Aghdass Rasouli-Nia, Jan G. Hengstler, Alejandra Mantilla, Hamid Reza Soleimanpour-Lichaei, Wolfgang Engel, Craig N. Robson, Karim Nayernia
Journal: Cancer Research
Cancer Res (2010) 70 (11): 4569–4579.
https://doi.org/10.1158/0008-5472.CAN-09-2670
Published: 01 June 2010
View articletitled, Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2
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Includes: Supplementary data
Journal Articles

Coordinates in the Universe of Node-Negative Breast Cancer Revisited

Free
Marcus Schmidt, Jan G. Hengstler, Christian von Törne, Heinz Koelbl, Mathias C. Gehrmann
Journal: Cancer Research
Cancer Res (2009) 69 (7): 2695–2698.
https://doi.org/10.1158/0008-5472.CAN-08-4013
Published: 01 April 2009
View articletitled, Coordinates in the Universe of Node-Negative Breast Cancer Revisited
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Includes: Supplementary data
Journal Articles

The Humoral Immune System Has a Key Prognostic Impact in Node-Negative Breast Cancer

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Marcus Schmidt, Daniel Böhm, Christian von Törne, Eric Steiner, Alexander Puhl, Henryk Pilch, Hans-Anton Lehr, Jan G. Hengstler, Heinz Kölbl, Mathias Gehrmann
Journal: Cancer Research
Cancer Res (2008) 68 (13): 5405–5413.
https://doi.org/10.1158/0008-5472.CAN-07-5206
Published: 01 July 2008
View articletitled, The Humoral Immune System Has a Key Prognostic Impact in Node-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

ERBB2-Mediated Transcriptional Up-regulation of the α5β1 Integrin Fibronectin Receptor Promotes Tumor Cell Survival Under Adverse Conditions

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Christian Spangenberg, Ekkehart U. Lausch, Tatjana M. Trost, Dirk Prawitt, Andreas May, Romy Keppler, Stephan A. Fees, Dirk Reutzel, Carolin Bell, Steffen Schmitt, Ilka B. Schiffer, Achim Weber, Walburgis Brenner, Matthias Hermes, Ugur Sahin, Özlem Türeci, Heinz Koelbl, Jan G. Hengstler, Bernhard U. Zabel
Journal: Cancer Research
Cancer Res (2006) 66 (7): 3715–3725.
https://doi.org/10.1158/0008-5472.CAN-05-2823
Published: 03 April 2006
View articletitled, ERBB2-Mediated Transcriptional Up-regulation of the α5β1 Integrin Fibronectin Receptor Promotes Tumor Cell Survival Under Adverse Conditions
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Journal Articles

Premature Senescence Is a Primary Fail-safe Mechanism of ERBB2-Driven Tumorigenesis in Breast Carcinoma Cells

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Tatjana M. Trost, Ekkehart U. Lausch, Stephan A. Fees, Steffen Schmitt, Thorsten Enklaar, Dirk Reutzel, Lili R. Brixel, Peter Schmidtke, Marko Maringer, Ilka B. Schiffer, Carolin K. Heimerdinger, Jan G. Hengstler, Gerhard Fritz, Ernst O. Bockamp, Dirk Prawitt, Bernhard U. Zabel, Christian Spangenberg
Journal: Cancer Research
Cancer Res (2005) 65 (3): 840–849.
https://doi.org/10.1158/0008-5472.840.65.3
Published: 10 February 2005
View articletitled, Premature Senescence Is a Primary Fail-safe Mechanism of ERBB2-Driven Tumorigenesis in Breast Carcinoma Cells
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Journal Articles

Switching Off HER-2/neu in a Tetracycline-Controlled Mouse Tumor Model Leads to Apoptosis and Tumor-Size-Dependent Remission

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Ilka B. Schiffer, Susanne Gebhard, Carolin K. Heimerdinger, Annette Heling, Jochem Hast, Ursula Wollscheid, Barbara Seliger, Berno Tanner, Sandra Gilbert, Thomas Beckers, Silke Baasner, Walburgis Brenner, Christian Spangenberg, Dirk Prawitt, Tatjana Trost, Wolfgang G. Schreiber, Bernhard Zabel, Manfred Thelen, Hans-Anton Lehr, Franz Oesch, Jan G. Hengstler
Journal: Cancer Research
Cancer Res (2003) 63 (21): 7221–7231.
Published: 11 November 2003
View articletitled, Switching Off HER-2/neu in a Tetracycline-Controlled Mouse Tumor Model Leads to Apoptosis and Tumor-Size-Dependent Remission
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Journal Articles

Contribution of c-erbB-2 and Topoisomerase IIα to Chemoresistance in Ovarian Cancer

Free
Jan G. Hengstler, Jost Lange, Alexandra Kett, Nadja Dornhöfer, Rolf Meinert, Michael Arand, Paul G. Knapstein, Roger Becker, Franz Oesch, Berno Tanner
Journal: Cancer Research
Cancer Res (1999) 59 (13): 3206–3214.
Published: 01 July 1999
View articletitled, Contribution of c-erbB-2 and Topoisomerase IIα to Chemoresistance in Ovarian Cancer
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