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Journal Articles

Abstract 1095: Overcoming acquired cetuximab resistance in head and neck squamous cell carcinoma: An in vitro study on the potential of PI3K inhibition

Hannah Zaryouh, Hasan Baysal, Patrick Pauwels, Marc Peeters, Jan B. Vermorken, Filip Lardon, An Wouters, Ines De Pauw

Cancer Res (2021) 81 (13_Supplement): 1095.

DOI: https://doi.org/10.1158/1538-7445.AM2021-1095

Published: 01 July 2021

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Journal Articles

Abstract 4102: Overcoming intrinsic and acquired cetuximab resistance: an in vitro study on the potential of afatinib in HNSCC cell lines

Ines De Pauw, An Wouters, Jolien Van den Bossche, Vanessa Deschoolmeester, Patrick Pauwels, Jan B. Vermorken, Marc Peeters, Filip Lardon

Cancer Res (2017) 77 (13_Supplement): 4102.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4102

Published: 01 July 2017

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Journal Articles

Abstract 5628: Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP6.

Carolien Boeckx, Vanessa Deschoolmeester, An Wouters, Ken Op de Beeckx, Patrick Pauwels, Olivier Vanderveken, Guy van Camp, Wim Vanden Berghe, Pol Specenier, Jan B. Vermorken, Marc Peeters, Marc Baay, Filip Lardon

Cancer Res (2013) 73 (8_Supplement): 5628.

DOI: https://doi.org/10.1158/1538-7445.AM2013-5628

Published: 15 April 2013

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Journal Articles

Abstract 1030: The intriguing interplay between EGFR inhibitors and the hypoxic microenvironment: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines.

Carolien Boeckx, Jolien Van den Bossche, Marc Baay, Vanessa Deschoolmeester, Pol Specenier, Olivier Vanderveken, Danielle Van den Weyngaert, Jan B. Vermorken, Marc Peeters, Filip Lardon, An Wouters

Cancer Res (2013) 73 (8_Supplement): 1030.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1030

Published: 15 April 2013

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Journal Articles

Abstract 5722: Retention of the radiosensitizing effect of gemcitabine and its main metabolite dFdU under reduced oxygen conditions is not influenced by HIF-1 functionality

An Wouters, Bea Pauwels, Natalie Burrows, Hilde Lambrechts, Greet Pattyn, Marc Baay, Vanessa Deschoolmeester, Kris Laukens, Paul Meijnders, Dirk Van Gestel, Daniëlle Van den Weyngaert, Kaye J. Williams, Jan B. Vermorken, Marc Peeters, Filip Lardon

Cancer Res (2012) 72 (8_Supplement): 5722.

DOI: https://doi.org/10.1158/1538-7445.AM2012-5722

Published: 15 April 2012

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Journal Articles

Abstract 1898: Potential molecular mechanisms of intrinsic resistance to EGFR-targeting monoclonal antibodies in HNSCC

Carolien Boeckx, Ridha Limame, Ken Op de Beeck, An Wouters, Vanessa Deschoolmeester, Pol Specenier, Jan B. Vermorken, Marc Peeters, Guy Van Camp, Marc Baay, Filip Lardon

Cancer Res (2012) 72 (8_Supplement): 1898.

DOI: https://doi.org/10.1158/1538-7445.AM2012-1898

Published: 15 April 2012

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Journal Articles

Abstract 2671: Study of the role of functional HIF-1 in the in vitro radiosensitizing effect of gemcitabine in normoxic and anoxic breast adenocarcinoma cells

An Wouters, Filip Lardon, Johan Ides, Marc Baay, Hilde A.J. Lambrechts, Greet G.O. Pattyn, Paul Meijnders, Patrick Pauwels, Kaye J. Williams, Jan B. Vermorken, Marc Peeters, Bea Pauwels

Cancer Res (2011) 71 (8_Supplement): 2671.

DOI: https://doi.org/10.1158/1538-7445.AM2011-2671

Published: 15 April 2011

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Journal Articles

Abstract 2661: The role of HIF-1 protein on the radiosensitizing effect of difluorodeoxyuridine, the main metabolite of gemcitabine, under normoxic and anoxic conditions

Bea Pauwels, An Wouters, Jan B. Vermorken, Johan Ides, Vanessa Deschoolmeester, Hilde AJ Lambrechts, Greet GO Pattyn, Paul Meijnders, Patrick Pauwels, Kaye J. Williams, Marc Peeters, Filip Lardon

Cancer Res (2011) 71 (8_Supplement): 2661.

DOI: https://doi.org/10.1158/1538-7445.AM2011-2661

Published: 15 April 2011

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Journal Articles

Abstract 5551: The role of hypoxia-inducible factor-1 (HIF-1) protein on the radiosensitizing effect of gemcitabine, in vitro, under normoxic and anoxic conditions

Bea Pauwels, An Wouters, Johan Ides, Greet Pattyn, Hilde Lambrechts, Kaye Williams, Paul Meijnders, Jan B. Vermorken, Patrick Pauwels, Marc Peeters, Filip Lardon

Cancer Res (2010) 70 (8_Supplement): 5551.

DOI: https://doi.org/10.1158/1538-7445.AM10-5551

Published: 15 April 2010

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Journal Articles

Abstract 460: Influence of low oxygen conditions on the in vitro radiosensitizing effect of gemcitabine, in p53 wild type and p53 deficient non-small cell lung carcinoma cells

An Wouters, Bea Pauwels, Hilde AJ Lambrechts, Greet GO Pattyn, Paul Meijnders, Patrick Pauwels, Marc Peeters, Jan B. Vermorken, Filip Lardon

Cancer Res (2010) 70 (8_Supplement): 460.

DOI: https://doi.org/10.1158/1538-7445.AM10-460

Published: 15 April 2010

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Journal Articles

Abstract 2122: KRAS mutation detection using high resolution melting analysis and its prognostic value in archival colorectal cancer tissues

Vanessa Deschoolmeester, Carolien Boeckx, Wim Wuyts, Eric Van Marck, Peter Vermeulen, Patrick Pauwels, Marc Peeters, Filip Lardon, Jan B. Vermorken, Marc Baay

Cancer Res (2010) 70 (8_Supplement): 2122.

DOI: https://doi.org/10.1158/1538-7445.AM10-2122

Published: 15 April 2010

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Journal Articles

In vitro interaction between pemetrexed and gemcitabine using different treatment schedules.

An Wouters, Bea Pauwels, Cindy Simoens, Hilde A J Lambrechts, Greet G O Pattyn, Jan B. Vermorken, Filip Lardon

Cancer Res (2006) 66 (8_Supplement): 1278–1279.

Published: 15 April 2006

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Journal Articles

Correlation between the radiosensitising effect of vinflunine (VFL) and its cell cycle effects, in different treatment schedules

Cindy Simoens, Filip Lardon, Bea Pauwels, Christel De Pooter, Fabienne Breillout, Jan B. Vermorken

Cancer Res (2006) 66 (8_Supplement): 488.

Published: 15 April 2006

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Journal Articles

Microsatellite instability in a Belgian colorectal cancer population: Prevalence and prognostic value

Vanessa C. Deschoolmeester, Nancy Van Damme, Marc Baay, Kathleen Claes, Eric Van Marck, Wim Wuyts, Joost Weyler, Filip Lardon, Jan B. Vermorken, Mark Peeters

Cancer Res (2006) 66 (8_Supplement): 52.

Published: 15 April 2006

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Journal Articles

Study to the apoptotic pathway responsible for the radiosensitizing effect of gemcitabine

Bea Pauwels, Veronique Huygelen, Hilde Aj Lambrechts, Greet Go Pattyn, Dirk R. Van Bockstaele, Katrien Vermeulen, Marc Lenjou, Christel Mj De Pooter, Jan B. Vermorken, Filip Lardon

Cancer Res (2006) 66 (8_Supplement): 137.

Published: 15 April 2006

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Journal Articles

The relation between deoxycytidine kinase activity and the radiosensitizing effect of gemcitabine in eight different human tumor cell lines

Filip Lardon, Bea Pauwels, Annelies E. C. Korst, Hilde A. J. Lambrechts, Greet G. O. Pattyn, Juliette A. E. Kamphuis, Christel M. J. De Pooter, Godefridus J. Peters, Jan B. Vermorken

Cancer Res (2005) 65 (9_Supplement): 341.

Published: 01 May 2005

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Journal Articles

Vinflunine (VFL) versus vinorelbine (VRL) and their interaction with radiation in vitro, preliminary results

Cindy Simoens, Filip Lardon, Christel M. De Pooter, Fabienne Breillout, Jan B. Vermorken

Cancer Res (2005) 65 (9_Supplement): 343.

Published: 01 May 2005

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Journal Articles

Difluorodeoxyuridine, the main metabolite of gemcitabine, can be partly responsible for the radiosensitizing effect of gemcitabine

Bea Pauwels, Annelies E. C. Korst, Greet G. O. Pattyn, Hilde A. J. Lambrechts, Christel M. J. De Pooter, Filip Lardon, Jan B. Vermorken

Cancer Res (2005) 65 (9_Supplement): 340.

Published: 01 May 2005

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Journal Articles

Cell cycle effects of Vinflunine, the latest novel Vinca alkaloid

Filip Lardon, Cindy Simoens, Annelies E. Korst, Greet G. Pattyn, Hilde A. Lambrechts, Fabienne Breillout, Jan B. Vermorken

Cancer Res (2004) 64 (7_Supplement): 193.

Published: 01 April 2004

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Journal Articles

Role of p53 in the radiosensitizing effect of gemcitabine, in vitro

Bea Pauwels, Annelies E. Korst, Veronique Andriessen, Marc F. Baay, Greet G. Pattyn, Hilde A. Lambrechts, Christel M. De Pooter, Filip Lardon, Jan B. Vermorken

Cancer Res (2004) 64 (7_Supplement): 309–310.

Published: 01 April 2004

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NARROW

Abstract 1095: Overcoming acquired cetuximab resistance in head and neck squamous cell carcinoma: An in vitro study on the potential of PI3K inhibition

Abstract 4102: Overcoming intrinsic and acquired cetuximab resistance: an in vitro study on the potential of afatinib in HNSCC cell lines

Abstract 5628: Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP6.

Abstract 1030: The intriguing interplay between EGFR inhibitors and the hypoxic microenvironment: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines.

Abstract 5722: Retention of the radiosensitizing effect of gemcitabine and its main metabolite dFdU under reduced oxygen conditions is not influenced by HIF-1 functionality

Abstract 1898: Potential molecular mechanisms of intrinsic resistance to EGFR-targeting monoclonal antibodies in HNSCC

Abstract 2671: Study of the role of functional HIF-1 in the in vitro radiosensitizing effect of gemcitabine in normoxic and anoxic breast adenocarcinoma cells

Abstract 2661: The role of HIF-1 protein on the radiosensitizing effect of difluorodeoxyuridine, the main metabolite of gemcitabine, under normoxic and anoxic conditions

Abstract 5551: The role of hypoxia-inducible factor-1 (HIF-1) protein on the radiosensitizing effect of gemcitabine, in vitro, under normoxic and anoxic conditions

Abstract 460: Influence of low oxygen conditions on the in vitro radiosensitizing effect of gemcitabine, in p53 wild type and p53 deficient non-small cell lung carcinoma cells

Abstract 2122: KRAS mutation detection using high resolution melting analysis and its prognostic value in archival colorectal cancer tissues

In vitro interaction between pemetrexed and gemcitabine using different treatment schedules.

Correlation between the radiosensitising effect of vinflunine (VFL) and its cell cycle effects, in different treatment schedules

Microsatellite instability in a Belgian colorectal cancer population: Prevalence and prognostic value

Study to the apoptotic pathway responsible for the radiosensitizing effect of gemcitabine

The relation between deoxycytidine kinase activity and the radiosensitizing effect of gemcitabine in eight different human tumor cell lines

Vinflunine (VFL) versus vinorelbine (VRL) and their interaction with radiation in vitro, preliminary results

Difluorodeoxyuridine, the main metabolite of gemcitabine, can be partly responsible for the radiosensitizing effect of gemcitabine

Cell cycle effects of Vinflunine, the latest novel Vinca alkaloid

Role of p53 in the radiosensitizing effect of gemcitabine, in vitro

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