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James W. Purcell
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Journal Articles

Exploiting LRRC15 as a Novel Therapeutic Target in Cancer

Upasana Ray, Christopher L. Pathoulas, Prabhu Thirusangu, James W. Purcell, Nagarajan Kannan, Viji Shridhar
Journal: Cancer Research
Cancer Res (2022) 82 (9): 1675–1681.
DOI: https://doi.org/10.1158/0008-5472.CAN-21-3734
Published: 03 May 2022
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Journal Articles

Targeting LRRC15 Inhibits Metastatic Dissemination of Ovarian Cancer

Upasana Ray, Deok-Beom Jung, Ling Jin, Yinan Xiao, Subramanyam Dasari, Sayantani Sarkar Bhattacharya, Prabhu Thirusangu, Julie K. Staub, Debarshi Roy, Bhaskar Roy, S. John Weroha, Xiaonan Hou, James W. Purcell, Jamie N. Bakkum-Gamez, Scott H. Kaufmann, Nagarajan Kannan, Anirban K. Mitra, Viji Shridhar
Journal: Cancer Research
Cancer Res (2022) 82 (6): 1038–1054.
DOI: https://doi.org/10.1158/0008-5472.CAN-21-0622
Published: 15 March 2022
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Includes: Supplementary data
Journal Articles

Abstract 2635: Role of LRRC15, a candidate immunotherapy target, in cell adhesion, migration and spheroid formation in osteosarcoma cells

Sanjit Mukherjee, Konrad Huppi, Robert L. Walker, Jack Zhu, Marbin Pineda, James W. Purcell, Lee J. Helman, Paul S. Meltzer
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2635.
DOI: https://doi.org/10.1158/1538-7445.AM2020-2635
Published: 15 August 2020
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Journal Articles

LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody–Drug Conjugates

James W. Purcell, Sonia G. Tanlimco, Jonathan Hickson, Melvin Fox, Mien Sho, Lisa Durkin, Tamar Uziel, Rick Powers, Kelly Foster, Thomas McGonigal, Subashri Kumar, Josue Samayoa, Dong Zhang, Joann P. Palma, Sasmita Mishra, Diane Hollenbaugh, Kurt Gish, Susan E. Morgan-Lappe, Eric D. Hsi, Debra T. Chao
Journal: Cancer Research
Cancer Res (2018) 78 (14): 4059–4072.
DOI: https://doi.org/10.1158/0008-5472.CAN-18-0327
Published: 15 July 2018
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Includes: Supplementary data
Journal Articles

Abstract 953: LRRC15 is a novel antigen in sarcoma and the therapeutic target of the antibody-drug conjugate (ADC) ABBV-085

Eytan Ben-Ami, Ying Huang, Prafulla C. Gokhale, Benjamin Eschle, Lisa Durkin, Jonathan Hickson, Mien Sho, Susan Morgan-Lappe, Kurt Gish, Dominic W. Lai, Randy R. Robinson, Diane Hollenbaugh, Eric D. Hsi, Debra T. Chao, George D. Demetri, James W. Purcell
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 953.
DOI: https://doi.org/10.1158/1538-7445.AM2018-953
Published: 01 July 2018
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Journal Articles

STAT1: A modulator of chemotherapy-induced apoptosis

Michelle Thomas, Clodagh E. Finnegan, Katherine M.-A. Rogers, James W. Purcell, Simon McDade, Patrick G. Johnston, Marion P. Boland
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1295.
Published: 01 May 2005
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Journal Articles

NFκB: A modulator of chemotherapy induced apoptosis

James W. Purcell, Mary Harte, Julia Gorski, Patrick J. Johnston, D. P. Harkin
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 197.
Published: 01 May 2005
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Journal Articles

STAT1: A Modulator of Chemotherapy-induced Apoptosis

Michelle Thomas, Clodagh E. Finnegan, Katherine M.-A. Rogers, James W. Purcell, Anne Trimble, Patrick G. Johnston, Marion P. Boland
Journal: Cancer Research
Cancer Res (2004) 64 (22): 8357–8364.
DOI: https://doi.org/10.1158/0008-5472.CAN-04-1864
Published: 17 November 2004
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