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James W. Freeman
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Journal Articles

Abstract 4166: Role of CD44 as a regulator of adaptive plasticity in pancreatic cancer cells

Chen Chen, Shujie Zhao, Xiangru Zhao, James W. Freeman
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4166.
https://doi.org/10.1158/1538-7445.AM2017-4166
Published: 01 July 2017
View articletitled, Abstract 4166: Role of CD44 as a regulator of adaptive plasticity in pancreatic cancer cells
Journal Articles

Abstract B68: Role of CD44 in pancreatic cancer cell plasticity

James W. Freeman, Shujie Zhao, Chen Chen, Anand Karnad
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B68.
https://doi.org/10.1158/1538-7445.PANCA16-B68
Published: 14 December 2016
View articletitled, Abstract B68: Role of CD44 in pancreatic cancer cell plasticity
Journal Articles

Abstract 4564: Elucidating the mechanism of the STAT3/NF-κB/EP4 signaling axis in pancreatic cancer

Amanda R. Munoz, James W. Freeman, Addanki P. Kumar
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4564.
https://doi.org/10.1158/1538-7445.AM2016-4564
Published: 15 July 2016
View articletitled, Abstract 4564: Elucidating the mechanism of the STAT3/NF-κB/EP4 signaling axis in pancreatic cancer
Journal Articles

Abstract A81: A microRNA signature identified for chemoresistance and mesenchymal phenotype is also found in advanced pancreatic cancer

James W. Freeman, Alakesh Bera, Venkatasubbarao Kolaparthi
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): A81.
https://doi.org/10.1158/1538-7445.PANCA2014-A81
Published: 30 June 2015
View articletitled, Abstract A81: A microRNA signature identified for chemoresistance and mesenchymal phenotype is also found in advanced pancreatic cancer
Journal Articles

Abstract B21: Disruption of NFκB/Stat3 interaction as a potential therapeutic avenue for pancreatic cancer management.

Jingjing Gong, Jianping Xie, Izhar Batth, James W. Freeman, Divya Chakravarthy, Addanki pratap Kumar
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): B21.
https://doi.org/10.1158/1538-7445.PANCA2012-B21
Published: 03 April 2014
View articletitled, Abstract B21: Disruption of NFκB/Stat3 interaction as a potential therapeutic avenue for pancreatic cancer management.
Journal Articles

Abstract 2320: Oncogenic K-ras and loss of Smad4 mediate invasion by activating a NF-kappaB/EGFR axis that induces expression of MMP9/uPA in human pancreas progenitor cells.

Alakesh Bera, Shujie Zhao, Lin Cao, James W. Freeman
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2320.
https://doi.org/10.1158/1538-7445.AM2013-2320
Published: 15 April 2013
View articletitled, Abstract 2320: Oncogenic K-ras and loss of Smad4 mediate invasion by activating a NF-kappaB/EGFR axis that induces expression of MMP9/uPA in human pancreas progenitor cells.
Journal Articles

Abstract 2717: Reolysin: A novel reovirus-based agent that induces endoplasmic reticular stress in RAS-activated pancreatic cancer

Jennifer S. Carew, Claudia M. Espitia, Kevin R. Kelly, Matt Coffey, James W. Freeman, Steffan T. Nawrocki
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2717.
https://doi.org/10.1158/1538-7445.AM2012-2717
Published: 15 April 2012
View articletitled, Abstract 2717: Reolysin: A novel reovirus-based agent that induces endoplasmic reticular stress in RAS-activated pancreatic cancer
Journal Articles

Abstract LB-22: Gemcitabine resistance is associated with EMT phenotype along with expression of cancer stem cell markers and a specific miRNA profile in the human pancreatic cancer cell line BxPC3

Alakesh Bera, James W. Freeman, Kolaparthi VenkataSubbaRao, Shujie Zhao
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-22.
https://doi.org/10.1158/1538-7445.AM2012-LB-22
Published: 15 April 2012
View articletitled, Abstract LB-22: Gemcitabine resistance is associated with EMT phenotype along with expression of cancer stem cell markers and a specific miRNA profile in the human pancreatic cancer cell line BxPC3
Journal Articles

Abstract 5389: Enhanced inhibition of proliferation of pancreatic cancer cells by combination of gemcitabine and phellodendron amurense bark extract: target identification

Jingjing Gong, James W. Freeman, Addanki Praptap Kumar
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5389.
https://doi.org/10.1158/1538-7445.AM10-5389
Published: 15 April 2010
View articletitled, Abstract 5389: Enhanced inhibition of proliferation of pancreatic cancer cells by combination of gemcitabine and phellodendron amurense bark extract: target identification
Journal Articles

Inhibition of STAT3Tyr705 Phosphorylation by Smad4 Suppresses Transforming Growth Factor β–Mediated Invasion and Metastasis in Pancreatic Cancer Cells

Shujie Zhao, Kolaparthi Venkatasubbarao, Jillian W. Lazor, Jane Sperry, Changqing Jin, Lin Cao, James W. Freeman
Journal: Cancer Research
Cancer Res (2008) 68 (11): 4221–4228.
https://doi.org/10.1158/0008-5472.CAN-07-5123
Published: 02 June 2008
View articletitled, Inhibition of STAT3Tyr705 Phosphorylation by Smad4 Suppresses Transforming Growth Factor β–Mediated Invasion and Metastasis in Pancreatic Cancer Cells
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Includes: Supplementary data
Journal Articles

Farnesyl Transferase Inhibitor (R115777)–Induced Inhibition of STAT3(Tyr705) Phosphorylation in Human Pancreatic Cancer Cell Lines Require Extracellular Signal-Regulated Kinases

Kolaparthi Venkatasubbarao, Ahsan Choudary, James W. Freeman
Journal: Cancer Research
Cancer Res (2005) 65 (7): 2861–2871.
https://doi.org/10.1158/0008-5472.CAN-04-2396
Published: 01 April 2005
View articletitled, Farnesyl Transferase Inhibitor (R115777)–Induced Inhibition of STAT3(Tyr705) Phosphorylation in Human Pancreatic Cancer Cell Lines Require Extracellular Signal-Regulated Kinases
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Journal Articles

Farnesyl transferase inhibitor (R115777) - induced inhibition of Stat3(Tyr 705) phosphorylation in human pancreatic cancer cell line PANC-1 requires Erk activation

Kolaparthi Venkatasubbarao, James W. Freeman, Kolaparthi Venkatasubbarao
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 892.
Published: 01 April 2004
View articletitled, Farnesyl transferase inhibitor (R115777) - induced inhibition of Stat3(Tyr 705) phosphorylation in human pancreatic cancer cell line PANC-1 requires Erk activation
Journal Articles

Requirement of a Specific Sp1 Site for Histone Deacetylase-mediated Repression of Transforming Growth Factor β Type II Receptor Expression in Human Pancreatic Cancer Cells

Shujie Zhao, Kolaparthi Venkatasubbarao, Senlin Li, James W. Freeman
Journal: Cancer Research
Cancer Res (2003) 63 (10): 2624–2630.
Published: 15 May 2003
View articletitled, Requirement of a Specific Sp1 Site for Histone Deacetylase-mediated Repression of Transforming Growth Factor β Type II Receptor Expression in Human Pancreatic Cancer Cells
Open the PDF for Requirement of a Specific Sp1 Site for Histone Deacetylase-mediated Repression of Transforming Growth Factor β Type II Receptor Expression in Human Pancreatic Cancer Cells in another window
Journal Articles

Reversion of Transcriptional Repression of Sp1 by 5 aza-2′ Deoxycytidine Restores TGF-β Type II Receptor Expression in the Pancreatic Cancer Cell Line MIA PaCa-2

Kolaparthi Venkatasubbarao, Sudhakar Ammanamanchi, Michael G. Brattain, Damon Mimari, James W. Freeman
Journal: Cancer Research
Cancer Res (2001) 61 (16): 6239–6247.
Published: 01 August 2001
View articletitled, Reversion of Transcriptional Repression of Sp1 by 5 aza-2′ Deoxycytidine Restores TGF-β Type II Receptor Expression in the Pancreatic Cancer Cell Line MIA PaCa-2
Open the PDF for Reversion of Transcriptional Repression of Sp1 by 5 aza-2′ Deoxycytidine Restores TGF-β Type II Receptor Expression in the Pancreatic Cancer Cell Line MIA PaCa-2 in another window
Journal Articles

Effect of Nucleolar P120 Expression Level on the Proliferation Capacity of Breast Cancer Cells

Anna Fonagy, Carol Swiderski, Alexander M. Ostrovsky, Wade E. Bolton, James W. Freeman
Journal: Cancer Research
Cancer Res (1994) 54 (7): 1859–1864.
Published: 01 April 1994
View articletitled, Effect of Nucleolar P120 Expression Level on the Proliferation Capacity of Breast Cancer Cells
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Journal Articles

Antisense-mediated Specific Inhibition of P120 Protein Expression Prevents G1- to S-Phase Transition

Anna Fonagy, Carol Swiderski, Melissa Dunn, James W. Freeman
Journal: Cancer Research
Cancer Res (1992) 52 (19): 5250–5256.
Published: 01 October 1992
View articletitled, Antisense-mediated Specific Inhibition of P120 Protein Expression Prevents G1- to S-Phase Transition
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Journal Articles

Expression of Nucleolar Antigen p145 in Bone Marrow Cells of Patients with Myeloid Leukemias

Azra Raza, Suzan Imren, Sefer Gezer, Lev Verkh, James W. Freeman
Journal: Cancer Research
Cancer Res (1989) 49 (2): 482–487.
Published: 01 January 1989
View articletitled, Expression of Nucleolar Antigen p145 in Bone Marrow Cells of Patients with Myeloid Leukemias
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Journal Articles

Intranucleolar Localization of Human Proliferating Cell Nucleolar Antigen p120

Robert L. Ochs, Mary T. Reilly, James W. Freeman, Harris Busch
Journal: Cancer Research
Cancer Res (1988) 48 (22): 6523–6529.
Published: 01 November 1988
View articletitled, Intranucleolar Localization of Human Proliferating Cell Nucleolar Antigen p120
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Journal Articles

Optimal Loading of Scraped HeLa Cells with Monoclonal Antibodies to the Proliferation-associated Mr 120,000 Nucleolar Antigen

James W. Freeman, Jeffrey E. Hazlewood, Patricia Auerbach, Harris Busch
Journal: Cancer Research
Cancer Res (1988) 48 (18): 5246–5250.
Published: 01 September 1988
View articletitled, Optimal Loading of Scraped HeLa Cells with Monoclonal Antibodies to the Proliferation-associated Mr 120,000 Nucleolar Antigen
Open the PDF for Optimal Loading of Scraped HeLa Cells with Monoclonal Antibodies to the Proliferation-associated Mr 120,000 Nucleolar Antigen in another window
Journal Articles

Identification and Characterization of a Human Proliferation-associated Nucleolar Antigen with a Molecular Weight of 120,000 Expressed in Early G1 Phase

James W. Freeman, Rose K. Busch, Ferenc Gyorkey, Phyllis Gyorkey, Brenda E. Ross, Harris Busch
Journal: Cancer Research
Cancer Res (1988) 48 (5): 1244–1251.
Published: 01 March 1988
View articletitled, Identification and Characterization of a Human Proliferation-associated Nucleolar Antigen with a Molecular Weight of 120,000 Expressed in Early G1 Phase
Open the PDF for Identification and Characterization of a Human Proliferation-associated Nucleolar Antigen with a Molecular Weight of 120,000 Expressed in Early G1 Phase in another window