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James W. Dennis
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Journal Articles

Mevalonate Pathway Inhibition Slows Breast Cancer Metastasis via Reduced N-glycosylation Abundance and Branching

Rosemary Yu, Joseph Longo, Jenna E. van Leeuwen, Cunjie Zhang, Emily Branchard, Mohamad Elbaz, David W. Cescon, Richard R. Drake, James W. Dennis, Linda Z. Penn
Journal: Cancer Research
Cancer Res (2021) 81 (10): 2625–2635.
https://doi.org/10.1158/0008-5472.CAN-20-2642
Published: 15 May 2021
View article titled, Mevalonate Pathway Inhibition Slows Breast Cancer Metastasis via Reduced <em>N</em>-glycosylation Abundance and Branching
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Includes: Supplementary data
Journal Articles

Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton

Karineh Kazazian, Christopher Go, Hannah Wu, Olga Brashavitskaya, Roland Xu, James W. Dennis, Anne-Claude Gingras, Carol J. Swallow
Journal: Cancer Research
Cancer Res (2017) 77 (2): 434–447.
https://doi.org/10.1158/0008-5472.CAN-16-2060
Published: 16 January 2017
View article titled, Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton
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Includes: Supplementary data
Journal Articles

Abstract 1031: Fumarate hydratase deficiency redirects glucose metabolism of hypoxic cancer cells into the pentose phosphate pathway

Luana Schito, Sergio Rey, Judy Pawling, James W. Dennis, Bradly G. Wouters, Marianne Koritzinsky
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1031.
https://doi.org/10.1158/1538-7445.AM2016-1031
Published: 15 July 2016
View article titled, Abstract 1031: Fumarate hydratase deficiency redirects glucose metabolism of hypoxic cancer cells into the pentose phosphate pathway
Journal Articles

Abstract LB-302: PTP1B regulates the Moyamoya disease-associated E3 ligase, RNF213 and cellular dioxygenase activity to allow breast tumor survival in hypoxia

Robert S. Banh, Caterina Iorio, Richard Marcotte, Yang Xu, Dan Cojocari, Anas Abdel Rahman, Judy Pawling, Ankit Sinha, Toshiaki Hitomi, Toshiyuki Habu, Akio Koizumi, Sarah Wilkins, Thomas Kislinger, Christopher J. Schofield, James W. Dennis, Bradly G. Wouters, Benjamin G. Neel
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-302.
https://doi.org/10.1158/1538-7445.AM2015-LB-302
Published: 01 August 2015
View article titled, Abstract LB-302: PTP1B regulates the Moyamoya disease-associated E3 ligase, RNF213 and cellular dioxygenase activity to allow breast tumor survival in hypoxia
Journal Articles

Abstract 2324: RhoGTPase-based regulation of cell motility by Plk4.

Volha (Olga) Brashavitskaya, Karineh Kazazian, Rick Bagshaw, Carla O. Rosario, Francis S W Zih, Yosr Haffani, James W. Dennis, Tony J. Pawson, Carol J. Swallow
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2324.
https://doi.org/10.1158/1538-7445.AM2013-2324
Published: 15 April 2013
View article titled, Abstract 2324: RhoGTPase-based regulation of cell motility by Plk4.
Journal Articles

Abstract 1484: Inhibition of the glycosylation enzyme Mgat1 blocks migration, invasion and metastasis of malignant cells

Reza Beheshti Zavareh, Rose Hurren, Marcela Gronda, Mahadeo A. Sukhai, Craig D. Simpson, Xiaoming Wang, Neil A. MacLean, Troy Ketela, Jason Moffat, David R. Rose, Harry Schachter, James W. Dennis, Aaron D. Schimmer
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1484.
https://doi.org/10.1158/1538-7445.AM2011-1484
Published: 15 April 2011
View article titled, Abstract 1484: Inhibition of the glycosylation enzyme Mgat1 blocks migration, invasion and metastasis of malignant cells
Journal Articles

Abstract 2331: Role of MMP expression in the effect of Plk4 on cell migration and invasion

Volha Brashavitskaya, Carla O. Rosario, James W. Dennis, Carol J. Swallow
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2331.
https://doi.org/10.1158/1538-7445.AM2011-2331
Published: 15 April 2011
View article titled, Abstract 2331: Role of MMP expression in the effect of Plk4 on cell migration and invasion
Journal Articles

Inhibition of the Sodium/Potassium ATPase Impairs N-Glycan Expression and Function

Reza Beheshti Zavareh, Ken S. Lau, Rose Hurren, Alessandro Datti, David J. Ashline, Marcela Gronda, Pam Cheung, Craig D. Simpson, Wei Liu, Amanda R. Wasylishen, Paul C. Boutros, Hui Shi, Amudha Vengopal, Igor Jurisica, Linda Z. Penn, Vern N. Reinhold, Shereen Ezzat, Jeff Wrana, David R. Rose, Harry Schachter, James W. Dennis, Aaron D. Schimmer
Journal: Cancer Research
Cancer Res (2008) 68 (16): 6688–6697.
https://doi.org/10.1158/0008-5472.CAN-07-6833
Published: 12 August 2008
View article titled, Inhibition of the Sodium/Potassium ATPase Impairs <em>N</em>-Glycan Expression and Function
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Journal Articles

Complex N-Glycan and Metabolic Control in Tumor Cells

Richard Mendelsohn, Pam Cheung, Lloyd Berger, Emily Partridge, Ken Lau, Alessandro Datti, Judy Pawling, James W. Dennis
Journal: Cancer Research
Cancer Res (2007) 67 (20): 9771–9780.
https://doi.org/10.1158/0008-5472.CAN-06-4580
Published: 17 October 2007
View article titled, Complex <em>N</em>-Glycan and Metabolic Control in Tumor Cells
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Includes: Supplementary data
Journal Articles

Chemical Enhancers of Cytokine Signaling that Suppress Microfilament Turnover and Tumor Cell Growth

Hyun-Joo Park, Emily Partridge, Pam Cheung, Judy Pawling, Rob Donovan, Jeffrey L. Wrana, James W. Dennis
Journal: Cancer Research
Cancer Res (2006) 66 (7): 3558–3566.
https://doi.org/10.1158/0008-5472.CAN-05-2542
Published: 03 April 2006
View article titled, Chemical Enhancers of Cytokine Signaling that Suppress Microfilament Turnover and Tumor Cell Growth
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Journal Articles

High incidence of Sak loss of heterozygosity in human hepatocellular carcinoma

Carla O. Rosario, Michael A. Ko, Aaron Pollett, Ian McGilvray, James W. Dennis, Carol J. Swallow
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 449.
Published: 01 May 2005
View article titled, High incidence of Sak loss of heterozygosity in human hepatocellular carcinoma
Journal Articles

α2HS-glycoprotein, an Antagonist of Transforming Growth Factor β In vivo , Inhibits Intestinal Tumor Progression

Carol J. Swallow, Emily A. Partridge, Jennifer C. Macmillan, Tania Tajirian, Gianni M. DiGuglielmo, Kazy Hay, Melanie Szweras, Willi Jahnen-Dechent, Jeff L. Wrana, Mark Redston, Steven Gallinger, James W. Dennis
Journal: Cancer Research
Cancer Res (2004) 64 (18): 6402–6409.
https://doi.org/10.1158/0008-5472.CAN-04-1117
Published: 16 September 2004
View article titled, α2HS-glycoprotein, an Antagonist of Transforming Growth Factor β <em>In vivo</em> , Inhibits Intestinal Tumor Progression
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Journal Articles

A Phase I Study of Swainsonine in Patients with Advanced Malignancies

Paul E. Goss, Jose Baptiste, Berny Fernandes, Michael Baker, James W. Dennis
Journal: Cancer Research
Cancer Res (1994) 54 (6): 1450–1457.
Published: 01 March 1994
View article titled, A Phase I Study of Swainsonine in Patients with Advanced Malignancies
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Journal Articles

Growth Inhibition of Human Melanoma Tumor Xenografts in Athymic Nude Mice by Swainsonine

James W. Dennis, Kay Koch, Shida Yousefi, Ingrid VanderElst
Journal: Cancer Research
Cancer Res (1990) 50 (6): 1867–1872.
Published: 01 March 1990
View article titled, Growth Inhibition of Human Melanoma Tumor Xenografts in Athymic Nude Mice by Swainsonine
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Journal Articles

Glycosylation-dependent Collagen-binding Activities of Two Membrane Glycoproteins in MDAY-D2 Tumor Cells

Suzanne Laferté, James W. Dennis
Journal: Cancer Research
Cancer Res (1988) 48 (17): 4743–4748.
Published: 01 September 1988
View article titled, Glycosylation-dependent Collagen-binding Activities of Two Membrane Glycoproteins in MDAY-D2 Tumor Cells
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Journal Articles

Isolation and Characterization of Spontaneous Wheat Germ Agglutinin-resistant Human Melanoma Mutants Displaying Remarkably Different Metastatic Profiles in Nude Mice

Makoto Ishikawa, James W. Dennis, Shan Man, Robert S. Kerbel
Journal: Cancer Research
Cancer Res (1988) 48 (3): 665–670.
Published: 01 February 1988
View article titled, Isolation and Characterization of Spontaneous Wheat Germ Agglutinin-resistant Human Melanoma Mutants Displaying Remarkably Different Metastatic Profiles in Nude Mice
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Journal Articles

Glycosphingolipids of Lectin-resistant Mutants of the Highly Metastatic Mouse Tumor Cell Line, MDAY-D2

Suzanne Laferté, Michiko N. Fukuda, Minoru Fukuda, Anne Dell, James W. Dennis
Journal: Cancer Research
Cancer Res (1987) 47 (1): 150–159.
Published: 01 January 1987
View article titled, Glycosphingolipids of Lectin-resistant Mutants of the Highly Metastatic Mouse Tumor Cell Line, MDAY-D2
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Journal Articles

Effects of Swainsonine and Polyinosinic:Polycytidylic Acid on Murine Tumor Cell Growth and Metastasis

James W. Dennis
Journal: Cancer Research
Cancer Res (1986) 46 (10): 5131–5136.
Published: 01 October 1986
View article titled, Effects of Swainsonine and Polyinosinic:Polycytidylic Acid on Murine Tumor Cell Growth and Metastasis
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Journal Articles

Different Metastatic Phenotypes in Two Genetic Classes of Wheat Germ Agglutinin-resistant Tumor Cell Mutants

James W. Dennis
Journal: Cancer Research
Cancer Res (1986) 46 (9): 4594–4600.
Published: 01 September 1986
View article titled, Different Metastatic Phenotypes in Two Genetic Classes of Wheat Germ Agglutinin-resistant Tumor Cell Mutants
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Journal Articles

Recognition of Asparagine-linked Oligosaccharides on Murine Tumor Cells by Natural Killer Cells

James W. Dennis, Suzanne Laferté
Journal: Cancer Research
Cancer Res (1985) 45 (12_Part_1): 6034–6040.
Published: 01 December 1985
View article titled, Recognition of Asparagine-linked Oligosaccharides on Murine Tumor Cells by Natural Killer Cells
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