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James R. Eshleman
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Journal Articles

Abstract LB397: Simultaneous CRISPR-Cas9 induced double strand breaks causes chromosomal catastrophe in pancreatic cancers: A parallel comparison with ionizing radiation

Selina Shiqing K. Teh, Akhil Kotwal, Eitan Halper-Stromberg, Laura Morsberger, Kirsten Bowland, Alexis Bennett, Michael Goldstein, Ying S. Zou, James R. Eshleman
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB397.
https://doi.org/10.1158/1538-7445.AM2024-LB397
Published: 05 April 2024
View article titled, Abstract LB397: Simultaneous CRISPR-Cas9 induced double strand breaks causes chromosomal catastrophe in pancreatic cancers: A parallel comparison with ionizing radiation
Journal Articles

Abstract 7243: CRISPR-cas9 genetic targeting of metastatic pancreatic cancer

Kirsten Bowland, Jiaying Lai, Selina Shiqing K. Teh, Alexis Bennett, Alyza Skaist, Yan Zhang, Elizabeth Thompson, Ralph H. Hruban, Nicholas J. Roberts, Rachel Karchin, Christine A. Iacobuzio-Donahue, James R. Eshleman
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7243.
https://doi.org/10.1158/1538-7445.AM2024-7243
Published: 22 March 2024
View article titled, Abstract 7243: CRISPR-cas9 genetic targeting of metastatic pancreatic cancer
Journal Articles

Abstract LB357: CRISPR-Cas9 targeting of somatic mutations selectively kills cancer cells

Kirsten Bowland, Selina Shiqing K. Teh, Alyza Skaist, Ralph H. Hruban, Nicholas J. Roberts, Chrisine Iacobuzio-Donahue, James R. Eshleman
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB357.
https://doi.org/10.1158/1538-7445.AM2023-LB357
Published: 14 April 2023
View article titled, Abstract LB357: CRISPR-Cas9 targeting of somatic mutations selectively kills cancer cells
Journal Articles

Abstract 6103: Genomic instability delays cell death in PDAC after simultaneous double strand breaks

Selina Shiqing K. Teh, Eitan Halper-Stromberg, Laura Morsberger, Kirsten Bowland, Alexis Bennett, Robert B. Scharpf, Ying S. Zou, James R. Eshleman
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6103.
https://doi.org/10.1158/1538-7445.AM2023-6103
Published: 04 April 2023
View article titled, Abstract 6103: Genomic instability delays cell death in PDAC after simultaneous double strand breaks
Journal Articles

Abstract 237: Coincidence of InDels with missense mutations: 0, 1 or 2 artifacts

Kelly E. Craven, Catherine G. Fischer, LiQun Jiang, Aparna Pallavajjala, Ming-Tseh Lin, James R. Eshleman
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 237.
https://doi.org/10.1158/1538-7445.AM2023-237
Published: 04 April 2023
View article titled, Abstract 237: Coincidence of InDels with missense mutations: 0, 1 or 2 artifacts
Journal Articles

Abstract 3954: Evaluation of long mononucleotide repeat markers for detection of microsatellite instability

Suping Chen, John H. Lin, Aparna Pallavajjala, Tamara L. Lotan, Jeffery W. Bacher, James R. Eshleman
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3954.
https://doi.org/10.1158/1538-7445.AM2023-3954
Published: 04 April 2023
View article titled, Abstract 3954: Evaluation of long mononucleotide repeat markers for detection of microsatellite instability
Journal Articles

Abstract 740: Improved microsatellite instability detection in endometrial and prostate cancers using long mononucleotide repeat markers

John H. Lin, Suping Chen, Liana B. Guedes, Emmanuel S. Antonarakis, Colin C. Pritchard, Tamara L. Lotan, James R. Eshleman
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 740.
https://doi.org/10.1158/1538-7445.AM2020-740
Published: 15 August 2020
View article titled, Abstract 740: Improved microsatellite instability detection in endometrial and prostate cancers using long mononucleotide repeat markers
Journal Articles

Abstract 4441: Functional and clinical implications of an INDEL within the HuR regulatory region of the mitotic kinase inhibitor WEE1

Samantha Z. Brown, Avinoam Nevler, Henry T. Thomsett, Shruti Lal, Mahsa Zarei, Fernando Blanco, Joseph A. Cozzitorto, Alexis L. Norris-Kirby, Charles J. Yeo, Jordan M. Winter, James R. Eshleman, Jonathan R. Brody
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4441.
https://doi.org/10.1158/1538-7445.AM2018-4441
Published: 01 July 2018
View article titled, Abstract 4441: Functional and clinical implications of an INDEL within the HuR regulatory region of the mitotic kinase inhibitor WEE1
Journal Articles

Abstract 1378: Generating quality control reference standards to evaluate ultrasensitive variant detection

Marija Debeljak, Lisa Haley, Derek A. Anderson, Emily M. Adams, Masaya Suenaga, Katie Beierl, Ming-Tseh Lin, Michael Goggins, Christopher D. Gocke, James R. Eshleman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1378.
https://doi.org/10.1158/1538-7445.AM2016-1378
Published: 15 July 2016
View article titled, Abstract 1378: Generating quality control reference standards to evaluate ultrasensitive variant detection
Journal Articles

Abstract 3608: Detection of somatic structural variants using nanopore sequencing

Alexis L. Norris, Rachael E. Workman, Yunfan Fan, James R. Eshleman, Winston Timp
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3608.
https://doi.org/10.1158/1538-7445.AM2016-3608
Published: 15 July 2016
View article titled, Abstract 3608: Detection of somatic structural variants using nanopore sequencing
Journal Articles

Abstract 3935: CDKN2A/p16 is inactivated by the combination of inversion and translocation

Alexis L. Norris, Hirohiko Kamiyama, Ralph H. Hruban, James R. Eshleman
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3935.
https://doi.org/10.1158/1538-7445.AM2015-3935
Published: 01 August 2015
View article titled, Abstract 3935: CDKN2A/p16 is inactivated by the combination of inversion and translocation
Journal Articles

Abstract 4270: NGS based microhaplotype counting for ultrasensitive human DNA detection

Marija Debeljak, Donald N. Freed, Jane A. Welch, Lisa Haley, Katie Beierl, Brian S. Iglehart, Aparna Pallavajjala, Christopher D. Gocke, Mary S. Leffell, Ming-Tseh Lin, Laura D. Wood, Jonathan Pevsner, Sarah J. Wheelan, James R. Eshleman
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4270.
https://doi.org/10.1158/1538-7445.AM2015-4270
Published: 01 August 2015
View article titled, Abstract 4270: NGS based microhaplotype counting for ultrasensitive human DNA detection
Journal Articles

Abstract 4268: DNA copy number variation and driver mutation patterns of follicular thyroid tumors

Hyun-seok Kim, Kathleen Wilsbach, Aurelien Marti, Alireza Najafian, Alan K. Meeker, James R. Eshleman, Justin A. Bishop, Martha Zeiger, Christopher B. Umbricht
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4268.
https://doi.org/10.1158/1538-7445.AM2015-4268
Published: 01 August 2015
View article titled, Abstract 4268: DNA copy number variation and driver mutation patterns of follicular thyroid tumors
Journal Articles

Abstract 3481: Genetically-engineered mice as a cell line isolating tool

Hirohiko Kamiyama, Sherri Rauenzahn, Anirban Maitra, James R. Eshleman
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3481.
https://doi.org/10.1158/1538-7445.AM2014-3481
Published: 01 October 2014
View article titled, Abstract 3481: Genetically-engineered mice as a cell line isolating tool
Journal Articles

Abstract 4155: Personalized chemosensitivity profiling of cancers isolated from genetically-engineered mice.

Hirohiko Kamiyama, Sherri Rauenzahn, Joong Sup Shim, Jun O. Liu, Anirban Maitra, James R. Eshleman
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4155.
https://doi.org/10.1158/1538-7445.AM2013-4155
Published: 15 April 2013
View article titled, Abstract 4155: Personalized chemosensitivity profiling of cancers isolated from genetically-engineered mice.
Journal Articles

Abstract 2095: A virtual pyrogram generator to resolve ambiguity of pyrosequencing results

Guoli Chen, Matthew T. Olson, Alan O'Neill, Alexis Norris-Kirby, Katie Beierl, Shuko Harada, Marija Debeljak, Keila Rivera-Roman, Samantha Finley, Amanda Stafford, Christopher D. Gocke, Ming-Tseh Lin, James R. Eshleman
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2095.
https://doi.org/10.1158/1538-7445.AM2012-2095
Published: 15 April 2012
View article titled, Abstract 2095: A virtual pyrogram generator to resolve ambiguity of pyrosequencing results
Journal Articles

Abstract 2628: Genome-wide sequencing identifies ATM as a pancreatic cancer susceptibility gene

Nicholas J. Roberts, Yuchen Jiao, Jun Yu, Levy Kopelovich, Gloria M. Petersen, Melissa Bondy, Steven Gallinger, Ann G. Schwartz, Sapna Syngal, Michele L. Cote, Jennifer Axilbund, Richard Schulick, Syed Z. Ali, James R. Eshleman, Victor Velculescu, Michael Goggins, Bert Vogelstein, Nikolas Papadopoulous, Ralph H. Hruban, Kenneth W. Kinzler, Alison P. Klein
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2628.
https://doi.org/10.1158/1538-7445.AM2012-2628
Published: 15 April 2012
View article titled, Abstract 2628: Genome-wide sequencing identifies <em>ATM</em> as a pancreatic cancer susceptibility gene
Journal Articles

Abstract 536: A hypoxia-activated protein switch as a potential anticancer therapeutic

Chapman M. Wright, Marc Ostermeier, James R. Eshleman
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 536.
https://doi.org/10.1158/1538-7445.AM2011-536
Published: 15 April 2011
View article titled, Abstract 536: A hypoxia-activated protein switch as a potential anticancer therapeutic
Journal Articles

Abstract 1781: Use of SNP arrays to assess loss of heterozygosity in gliomas

Athanasios C. Tsiatis, Michael J. Hafez, Anne E. Jedlicka, Anirban Maitra, Kathleen M. Murphy, James R. Eshleman
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1781.
https://doi.org/10.1158/1538-7445.AM10-1781
Published: 15 April 2010
View article titled, Abstract 1781: Use of SNP arrays to assess loss of heterozygosity in gliomas
Journal Articles

Genetic Mutations Associated with Cigarette Smoking in Pancreatic Cancer

Amanda Blackford, Giovanni Parmigiani, Thomas W. Kensler, Christopher Wolfgang, Siân Jones, Xiaosong Zhang, D. Willams Parsons, Jimmy Cheng-Ho Lin, Rebecca J. Leary, James R. Eshleman, Michael Goggins, Elizabeth M. Jaffee, Christine A. Iacobuzio-Donahue, Anirban Maitra, Alison Klein, John L. Cameron, Kelly Olino, Richard Schulick, Jordan Winter, Bert Vogelstein, Victor E. Velculescu, Kenneth W. Kinzler, Ralph H. Hruban
Journal: Cancer Research
Cancer Res (2009) 69 (8): 3681–3688.
https://doi.org/10.1158/0008-5472.CAN-09-0015
Published: 15 April 2009
View article titled, Genetic Mutations Associated with Cigarette Smoking in Pancreatic Cancer
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Includes: Supplementary data