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James G. Jackson
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Journal Articles

Abstract 1297: Chemotherapy-induced senescence activates robust, parallel programs of immune checkpoint expression that can be targeted with immunotherapy

Free
Ashkan Shahbandi, Fang-Yen Chiu, Nathan A. Ungerleider, Ashlyn Y. Anderson, Heather L. Machado, Zachary F. Pursell, Raegan Kvadas, Sonia G. Rao, James G. Jackson
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1297.
https://doi.org/10.1158/1538-7445.AM2022-1297
Published: 15 June 2022
View articletitled, Abstract 1297: Chemotherapy-induced senescence activates robust, parallel programs of immune checkpoint expression that can be targeted with immunotherapy
Journal Articles

Abstract 1504: Mouse model and human patient data suggest critical roles for Pten and p53 in suppressing POLE mutant tumor development

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Meijuan J. Sun, Vivian S. Park, Wesley D. Frey, Leonard G. Williams, Karl P. Hodel, Juliet D. Strauss, Sydney J. Wellens, James G. Jackson, Zachary F. Pursell
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1504.
https://doi.org/10.1158/1538-7445.AM2022-1504
Published: 15 June 2022
View articletitled, Abstract 1504: Mouse model and human patient data suggest critical roles for Pten and p53 in suppressing POLE mutant tumor development
Journal Articles

Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade

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Melissa A. Galati, Karl P. Hodel, Miki S. Gams, Sumedha Sudhaman, Taylor Bridge, Walter J. Zahurancik, Nathan A. Ungerleider, Vivian S. Park, Ayse B. Ercan, Lazar Joksimovic, Iram Siddiqui, Robert Siddaway, Melissa Edwards, Richard de Borja, Dana Elshaer, Jiil Chung, Victoria J. Forster, Nuno M. Nunes, Melyssa Aronson, Xia Wang, Jagadeesh Ramdas, Andrea Seeley, Tomasz Sarosiek, Gavin P. Dunn, Jonathan N. Byrd, Oz Mordechai, Carol Durno, Alberto Martin, Adam Shlien, Eric Bouffet, Zucai Suo, James G. Jackson, Cynthia E. Hawkins, Cynthia J. Guidos, Zachary F. Pursell, Uri Tabori
Journal: Cancer Research
Cancer Res (2020) 80 (24): 5606–5618.
https://doi.org/10.1158/0008-5472.CAN-20-0624
Published: 15 December 2020
View articletitled, Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade
Open the PDF for Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade in another window
Includes: Supplementary data
Journal Articles

Abstract SY14-02: p53-mediated senescence impairs the apoptotic response to chemotherapy in breast cancer

Free
Guillermina Lozano, James G. Jackson
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): SY14-02.
https://doi.org/10.1158/1538-7445.AM2012-SY14-02
Published: 15 April 2012
View articletitled, Abstract SY14-02: p53-mediated senescence impairs the apoptotic response to chemotherapy in breast cancer
Journal Articles

Multiple Stress Signals Activate Mutant p53 In Vivo

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Young-Ah Suh, Sean M. Post, Ana C. Elizondo-Fraire, Daniela R. Maccio, James G. Jackson, Adel K. El-Naggar, Carolyn Van Pelt, Tamara Terzian, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2011) 71 (23): 7168–7175.
https://doi.org/10.1158/0008-5472.CAN-11-0459
Published: 29 November 2011
View articletitled, Multiple Stress Signals Activate Mutant p53 In Vivo
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Journal Articles

Abstract 1235: Induction of a p21 mediated senescence program by p53 impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer

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James G. Jackson, Leslie L. Chang, Alfonso Quintás-Cardama, Adel K. El-Naggar, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1235.
https://doi.org/10.1158/1538-7445.AM2011-1235
Published: 15 April 2011
View articletitled, Abstract 1235: Induction of a p21 mediated senescence program by p53 impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer
Journal Articles

p53 Is Preferentially Recruited to the Promoters of Growth Arrest Genes p21 and GADD45 during Replicative Senescence of Normal Human Fibroblasts

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James G. Jackson, Olivia M. Pereira-Smith
Journal: Cancer Research
Cancer Res (2006) 66 (17): 8356–8360.
https://doi.org/10.1158/0008-5472.CAN-06-1752
Published: 01 September 2006
View articletitled, p53 Is Preferentially Recruited to the Promoters of Growth Arrest Genes p21 and GADD45 during Replicative Senescence of Normal Human Fibroblasts
Open the PDF for p53 Is Preferentially Recruited to the Promoters of Growth Arrest Genes p21 and GADD45 during Replicative Senescence of Normal Human Fibroblasts in another window
Includes: Supplementary data
Journal Articles

Primary and compensatory roles of the RB family members in cell cycle gene regulation during the induction of the senescent like phenotype in doxorubicin treated MCF-7 cells

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James G. Jackson, Olivia Pereira-Smith
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 581.
Published: 15 April 2006
View articletitled, Primary and compensatory roles of the RB family members in cell cycle gene regulation during the induction of the senescent like phenotype in doxorubicin treated MCF-7 cells
Journal Articles

Blockade of Epidermal Growth Factor- or Heregulin-Dependent ErbB2 Activation with the Anti-ErbB2 Monoclonal Antibody 2C4 Has Divergent Downstream Signaling and Growth Effects

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James G. Jackson, Patricia St. Clair, Mark X. Sliwkowski, Michael G. Brattain
Journal: Cancer Research
Cancer Res (2004) 64 (7): 2601–2609.
https://doi.org/10.1158/0008-5472.CAN-03-3106
Published: 01 April 2004
View articletitled, Blockade of Epidermal Growth Factor- or Heregulin-Dependent ErbB2 Activation with the Anti-ErbB2 Monoclonal Antibody 2C4 Has Divergent Downstream Signaling and Growth Effects
Open the PDF for Blockade of Epidermal Growth Factor- or Heregulin-Dependent ErbB2 Activation with the Anti-ErbB2 Monoclonal Antibody 2C4 Has Divergent Downstream Signaling and Growth Effects in another window