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James G. Herman
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Journal Articles

Abstract 6510: REM-DREAMing: Low-cost digital microfluidic analysis of DNA methylation heterogeneity for enhanced, liquid biopsy-based detection of early-stage lung cancer

Yang Zhao, Christine M. O’Keefe, James G. Herman, Thomas R. Pisanic, Tza-Huei Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6510.
https://doi.org/10.1158/1538-7445.AM2023-6510
Published: 04 April 2023
View article titled, Abstract 6510: REM-DREAMing: Low-cost digital microfluidic analysis of DNA methylation heterogeneity for enhanced, liquid biopsy-based detection of early-stage lung cancer
Journal Articles

Abstract 3308: Urine epigenetic biomarkers for NSCLC diagnosis

Lane Lerner, Lily Zheng, Anastasia Kottorou, Chen Chen, Tomoaki Ito, Kristen Rodgers, Beverly Lee, Robert Winn, Enrico Benedetti, Tza- Huei Wang, Malcolm V. Brock, James G. Herman, Alicia Hulbert
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3308.
https://doi.org/10.1158/1538-7445.AM2018-3308
Published: 01 July 2018
View article titled, Abstract 3308: Urine epigenetic biomarkers for NSCLC diagnosis
Journal Articles

Abstract 3291: The human cancer DNA methylation marker atlas

Alexander Koch, Gerrit A. Meijer, James G. Herman, Wim Van Criekinge, Manon van Engeland
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3291.
https://doi.org/10.1158/1538-7445.AM2018-3291
Published: 01 July 2018
View article titled, Abstract 3291: The human cancer DNA methylation marker atlas
Journal Articles

Abstract 3365: Epigenetic inactivation of PTPRT and sensitivity to STAT3 inhibition in lung cancer

Malabika Sen, Audrey Kindsfather, James G. Herman
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3365.
https://doi.org/10.1158/1538-7445.AM2017-3365
Published: 01 July 2017
View article titled, Abstract 3365: Epigenetic inactivation of PTPRT and sensitivity to STAT3 inhibition in lung cancer
Journal Articles

Abstract 4450: Silencing NKD2 by promoter region hypermethylation promotes esophageal cancer progression by activating Wnt signaling

Mingzhou Guo, Baoping Cao, Weili Yang, Yongshuai Jin, Meiying Zhang, Tao He, Qimin Zhan, James G. Herman, Guanglin Zhong
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4450.
https://doi.org/10.1158/1538-7445.AM2016-4450
Published: 15 July 2016
View article titled, Abstract 4450: Silencing NKD2 by promoter region hypermethylation promotes esophageal cancer progression by activating Wnt signaling
Journal Articles

Abstract 1064: RASSF10 suppresses colorectal cancer growth by activating p53 signaling and sensitizes colorectal cancer cell to docetaxel

Jing Guo, Yage Yang, Yunsheng Yang, Enqiang Linghu, Qimin Zhan, Malcolm V. Brock, James G. Herman, Bingyong Zhang, Mingzhou Guo
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1064.
https://doi.org/10.1158/1538-7445.AM2015-1064
Published: 01 August 2015
View article titled, Abstract 1064: RASSF10 suppresses colorectal cancer growth by activating p53 signaling and sensitizes colorectal cancer cell to docetaxel
Journal Articles

The CpG Island Methylator Phenotype: What's in a Name?

Laura A.E. Hughes, Veerle Melotte, Joachim de Schrijver, Michiel de Maat, Vincent T.H.B.M. Smit, Judith V.M.G. Bovée, Pim J. French, Piet A. van den Brandt, Leo J. Schouten, Tim de Meyer, Wim van Criekinge, Nita Ahuja, James G. Herman, Matty P. Weijenberg, Manon van Engeland
Journal: Cancer Research
Cancer Res (2013) 73 (19): 5858–5868.
https://doi.org/10.1158/0008-5472.CAN-12-4306
Published: 01 October 2013
View article titled, The CpG Island Methylator Phenotype: What's in a Name?
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Journal Articles

Abstract 1155: Promoter CpG island hypermethylation of Decoy Receptor 1 (DCR1) is associated with poor response to irinotecan in colorectal cancer.

Linda JW Bosch, Geert Trooskens, Petur Snaebjornsson, Josien C. Haan, Lorraine Pelosof, Miriam Koopman, Jolien Tol, Joost Louwagie, Luc Dehaspe, Bauke Ylstra, Henk Verheul, Manon van Engeland, Iris D. Nagtegaal, James G. Herman, Cornelis JA Punt, Wim van Criekinge, Beatriz Carvalho, Gerrit A. Meijer
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1155.
https://doi.org/10.1158/1538-7445.AM2013-1155
Published: 15 April 2013
View article titled, Abstract 1155: Promoter CpG island hypermethylation of Decoy Receptor 1 (DCR1) is associated with poor response to irinotecan in colorectal cancer.
Journal Articles

Abstract 3536: BRCA1 promoter methylation and homologous recombination repair status in primary chronic myeloid neoplasms.

Weijie Poh, Robert L. Dilley, Alison R. Moliterno, Keith W. Pratz, Michael A. McDevitt, James G. Herman
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3536.
https://doi.org/10.1158/1538-7445.AM2013-3536
Published: 15 April 2013
View article titled, Abstract 3536: BRCA1 promoter methylation and homologous recombination repair status in primary chronic myeloid neoplasms.
Journal Articles

Abstract 94: Epigenetic silencing of CDO1 sustains viability of breast cancer cells via the reduction of cellular ROS

Jana Jeschke, Heather O'Hagan, Wei Zhang, Marilia F. Calmon, Mashaal Dhir, Leander van Neste, Ingrid Bijsmans, Edward Gabrielson, Kornel E. Schuebel, Stephen B. Baylin, Andreas Winterpacht, James G. Herman, Nita Ahuja
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 94.
https://doi.org/10.1158/1538-7445.AM2012-94
Published: 15 April 2012
View article titled, Abstract 94: Epigenetic silencing of CDO1 sustains viability of breast cancer cells via the reduction of cellular ROS
Journal Articles

Abstract 3142: Hypermethylation of the tissue inhibitor of metalloproteinases-2 gene in multiple myeloma

Stefan Wilop, Edgar Jost, Claudia Schubert, James G. Herman, Tim H. Brümmendorf, Oliver Galm
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3142.
https://doi.org/10.1158/1538-7445.AM2012-3142
Published: 15 April 2012
View article titled, Abstract 3142: Hypermethylation of the tissue inhibitor of metalloproteinases-2 gene in multiple myeloma
Journal Articles

Abstract 3993: MiRNA-141 and methylation regulation of WNT signal pathway by suppressing SOX17 in esophageal cancer

Mingzhou Guo, Yan Jia, Yunsheng Yang, Qimin Zhan, James G. Herman
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3993.
https://doi.org/10.1158/1538-7445.AM2012-3993
Published: 15 April 2012
View article titled, Abstract 3993: MiRNA-141 and methylation regulation of WNT signal pathway by suppressing <em>SOX17 i</em>n esophageal cancer
Journal Articles

Abstract 4025: Evaluation of homologous recombination (HR) genes in myeloproliferative neoplasms (MPNs) suggests BRCA1 as a potential biomarker for sensitivity to poly (ADP-ribose) polymerase (PARP) inhibition and disease progression

Weijie Poh, Robert Dilley, Keith W. Pratz, Michael A. McDevitt, James G. Herman
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4025.
https://doi.org/10.1158/1538-7445.AM2012-4025
Published: 15 April 2012
View article titled, Abstract 4025: Evaluation of homologous recombination (HR) genes in myeloproliferative neoplasms (MPNs) suggests BRCA1 as a potential biomarker for sensitivity to poly (ADP-ribose) polymerase (PARP) inhibition and disease progression
Journal Articles

Aberrant Silencing of Cancer-Related Genes by CpG Hypermethylation Occurs Independently of Their Spatial Organization in the Nucleus

Hariharan P. Easwaran, Leander Van Neste, Leslie Cope, Subhojit Sen, Helai P. Mohammad, Gayle J. Pageau, Jeanne B. Lawrence, James G. Herman, Kornel E. Schuebel, Stephen B. Baylin
Journal: Cancer Research
Cancer Res (2010) 70 (20): 8015–8024.
https://doi.org/10.1158/0008-5472.CAN-10-0765
Published: 13 October 2010
View article titled, Aberrant Silencing of Cancer-Related Genes by CpG Hypermethylation Occurs Independently of Their Spatial Organization in the Nucleus
Open the PDF for Aberrant Silencing of Cancer-Related Genes by CpG Hypermethylation Occurs Independently of Their Spatial Organization in the Nucleus in another window
Includes: Supplementary data
Journal Articles

Abstract 200: Methylation of GATA4 and GATA5 transcription factor genes in gastric cancers

Yoshimitsu Akiyama, Hiromi Nagasali, Ayako Kawamoto, James G. Herman, Stephen B. Baylin, Yasuhito Yuasa
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 200.
https://doi.org/10.1158/1538-7445.AM10-200
Published: 15 April 2010
View article titled, Abstract 200: Methylation of GATA4 and GATA5 transcription factor genes in gastric cancers
Journal Articles

Abstract LB-92: Loss of a single Hic1 allele accelerates polyp formation in Apc mice

Helai Mohammad, Wei Zhang, Helen Selonick, Benjamin Leadem, Minsi Zhang, Craig Hooker, David N. Watkins, Baktiar Karim, David Huso, James G. Herman, Stephen B. Baylin
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-92.
https://doi.org/10.1158/1538-7445.AM10-LB-92
Published: 15 April 2010
View article titled, Abstract LB-92: Loss of a single Hic1 allele accelerates polyp formation in Apc mice
Journal Articles

Progressive Chromatin Repression and Promoter Methylation of CTNNA1 Associated with Advanced Myeloid Malignancies

Ying Ye, Michael A. McDevitt, Mingzhou Guo, Wei Zhang, Oliver Galm, Steven D. Gore, Judith E. Karp, Jaroslaw P. Maciejewski, Jeanne Kowalski, Hua-Ling Tsai, Lukasz P. Gondek, Hsing-Chen Tsai, Xiaofei Wang, Craig Hooker, B. Douglas Smith, Hetty E. Carraway, James G. Herman
Journal: Cancer Research
Cancer Res (2009) 69 (21): 8482–8490.
https://doi.org/10.1158/0008-5472.CAN-09-1153
Published: 28 October 2009
View article titled, Progressive Chromatin Repression and Promoter Methylation of <em>CTNNA1</em> Associated with Advanced Myeloid Malignancies
Open the PDF for Progressive Chromatin Repression and Promoter Methylation of <em>CTNNA1</em> Associated with Advanced Myeloid Malignancies in another window
Includes: Supplementary data
Journal Articles

Methylation of TFPI2 in Stool DNA: A Potential Novel Biomarker for the Detection of Colorectal Cancer

Sabine C. Glöckner, Mashaal Dhir, Joo Mi Yi, Kelly E. McGarvey, Leander Van Neste, Joost Louwagie, Timothy A. Chan, Wolfram Kleeberger, Adriaan P. de Bruïne, Kim M. Smits, Carolina A.J. Khalid-de Bakker, Daisy M.A.E. Jonkers, Reinhold W. Stockbrügger, Gerrit A. Meijer, Frank A. Oort, Christine Iacobuzio-Donahue, Katja Bierau, James G. Herman, Stephen B. Baylin, Manon Van Engeland, Kornel E. Schuebel, Nita Ahuja
Journal: Cancer Research
Cancer Res (2009) 69 (11): 4691–4699.
https://doi.org/10.1158/0008-5472.CAN-08-0142
Published: 01 June 2009
View article titled, Methylation of <em>TFPI2</em> in Stool DNA: A Potential Novel Biomarker for the Detection of Colorectal Cancer
Open the PDF for Methylation of <em>TFPI2</em> in Stool DNA: A Potential Novel Biomarker for the Detection of Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract #4746: Relationship among gene methylation, azacitidine treatment, and survival in patients with higher-risk myelodysplastic syndromes (MDS): results from the AZA-001 trial

James G. Herman, Steven Gore, Ghulam Mufti, Pierre Fenaux, Valeria Santini, Lewis Silverman, John Seymour, Elizabeth Griffiths, Hetty Caraway, Kyle MacBeth, David McKenzie, Jay Backstrom, C. L. Beach
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4746.
Published: 01 May 2009
View article titled, Abstract #4746: Relationship among gene methylation, azacitidine treatment, and survival in patients with higher-risk myelodysplastic syndromes (MDS): results from the AZA-001 trial
Journal Articles

Abnormal DNA Methylation of CD133 in Colorectal and Glioblastoma Tumors

Joo Mi Yi, Hsing-Chen Tsai, Sabine C. Glöckner, Steven Lin, Joyce E. Ohm, Hari Easwaran, C. David James, Joseph F. Costello, Gregory Riggins, Charles G. Eberhart, John Laterra, Angelo L. Vescovi, Nita Ahuja, James G. Herman, Kornel E. Schuebel, Stephen B. Baylin
Journal: Cancer Research
Cancer Res (2008) 68 (19): 8094–8103.
https://doi.org/10.1158/0008-5472.CAN-07-6208
Published: 30 September 2008
View article titled, Abnormal DNA Methylation of <em>CD133</em> in Colorectal and Glioblastoma Tumors
Open the PDF for Abnormal DNA Methylation of <em>CD133</em> in Colorectal and Glioblastoma Tumors in another window
Includes: Supplementary data