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Abstract 5757: Study of human mammary tumor virus (HMTV) in human breast cancer by NanoString nCounter and FISH analysis

Stella M. Melana, Joseph Tripodi, Digna Nosike, Jaffer Shabnam, Polly Etkind, Beatriz GT Pogo, James F. Holland

Cancer Res (2017) 77 (13_Supplement): 5757.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5757

Published: 01 July 2017

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Journal Articles

Abstract 4062: Human mammary tumor virus (HMTV) is a breast cancer pathogen

James F. Holland, Stella Melana, Teiko Nartey, Joseph Tripodi, Shabnam Jaffer, Anupna Nayak, Beatriz GT Pogo

Cancer Res (2016) 76 (14_Supplement): 4062.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4062

Published: 15 July 2016

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Journal Articles

Abstract 694: Structure-function analysis of RPL18A, a putative binding target of rigosertib

Irina A. Oussenko, Yogesh K. Gupta, Rodrigo Vasquez-Del Carpio, M.V. Ramana-Reddy, Aneel K. Aggarwal, E. Premkumar Reddy, James F. Holland, Takao Ohnuma

Cancer Res (2015) 75 (15_Supplement): 694.

DOI: https://doi.org/10.1158/1538-7445.AM2015-694

Published: 01 August 2015

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Journal Articles

Abstract 821: Human mammary tumor virus(HMTV) is deeply involved in breast cancer and metastasis

James F. Holland, Stella Melana, Shabnam Jaffer, Polly Etkind, Teiko Nartey, Tina Lee, Beatriz G.T. Pogo

Cancer Res (2015) 75 (15_Supplement): 821.

DOI: https://doi.org/10.1158/1538-7445.AM2015-821

Published: 01 August 2015

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Journal Articles

Abstract 4595: RPL18A as putative target of rigosertib

Irina Oussenko, Saikrishna Divakar, M. V. Ramana Reddy, James F. Holland, E. Premkumar Reddy, Takao Ohnuma

Cancer Res (2014) 74 (19_Supplement): 4595.

DOI: https://doi.org/10.1158/1538-7445.AM2014-4595

Published: 01 October 2014

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Journal Articles

Abstract 1595: Human mammary tumor virus (HMTV) detection in surgical specimens and metastases of human breast cancer by the Nanostring nCounter system and FISH analysis

Stella M. Melana, Polly Etkind, Teiko Nartey, Yetunde Agbaje, James F. Holland, Beatriz G-T Pogo

Cancer Res (2014) 74 (19_Supplement): 1595.

DOI: https://doi.org/10.1158/1538-7445.AM2014-1595

Published: 01 October 2014

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Journal Articles

Abstract 3797: Hyperphosphorylation and desumoylation of RanGAP1·SUMO1

Irina Oussenko, James F. Holland, E. Premkumar Reddy, Takao Ohnuma

Cancer Res (2012) 72 (8_Supplement): 3797.

DOI: https://doi.org/10.1158/1538-7445.AM2012-3797

Published: 15 April 2012

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Journal Articles

Abstract 2675: CXCL12 (SDF-1) and its truncation products in patients with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) receiving ON 01910.Na (Rigosertib) in phase I trials

Sool Y. Cho, Shyamala C. Navada, Lewis R. Silverman, James F. Holland, John Roboz

Cancer Res (2012) 72 (8_Supplement): 2675.

DOI: https://doi.org/10.1158/1538-7445.AM2012-2675

Published: 15 April 2012

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Journal Articles

Abstract 5751: Detection of HMTV in breast and endometrium carcinomas

Stella M. Melana, Tania Marin, Teiko Nartey, Shabnam Jaffer, Liane Deligdisch, James F. Holland, Beatriz GT Pogo

Cancer Res (2012) 72 (8_Supplement): 5751.

DOI: https://doi.org/10.1158/1538-7445.AM2012-5751

Published: 15 April 2012

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Journal Articles

Effect of ON 01910.Na, an Anticancer Mitotic Inhibitor, on Cell-Cycle Progression Correlates with RanGAP1 Hyperphosphorylation

Irina A. Oussenko, James F. Holland, E. Premkumar Reddy, Takao Ohnuma

Cancer Res (2011) 71 (14): 4968–4976.

DOI: https://doi.org/10.1158/0008-5472.CAN-10-1603

Published: 14 July 2011

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Journal Articles

Abstract 2723: Host response to HMTV

Stella M. Melana, Mariana Fernandez-Cobo, Tania Marin, Teiko Nartey, Ana Lee, Herberth Moran, James F. Holland, Beatriz GT Pogo

Cancer Res (2011) 71 (8_Supplement): 2723.

DOI: https://doi.org/10.1158/1538-7445.AM2011-2723

Published: 15 April 2011

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Journal Articles

Abstract 2639: RanGAP1·SUMO1 hyperphosphorylation (RGSH) and mitotic arrest by ON 01910.Na, okadaic acid or tubulin agents

Irina Oussenko, James F. Holland, E. Premkumar Reddy, Takao Ohnuma

Cancer Res (2011) 71 (8_Supplement): 2639.

DOI: https://doi.org/10.1158/1538-7445.AM2011-2639

Published: 15 April 2011

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Journal Articles

Abstract 2302: Detection of HMTV env sequences in hormonally dependent tissues

Beatriz GT Pogo, Heberth Moran, Tania Marin, Anna Lee, Liane Deligdisch, Kathleen Ancaro, Douglas Anderton, Stella Melana, James F. Holland

Cancer Res (2011) 71 (8_Supplement): 2302.

DOI: https://doi.org/10.1158/1538-7445.AM2011-2302

Published: 15 April 2011

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Journal Articles

Abstract 2500: ON 01910. Na, a clinical stage anticancer mitotic inhibitor, produces prolonged hyperphosphorylation of RanGAP1•SUMO1 as a potential mechanism of G2/M arrest and apoptosis

Irina Oussenko, James F. Holland, E. Premkumar Reddy, Takao Ohnuma

Cancer Res (2010) 70 (8_Supplement): 2500.

DOI: https://doi.org/10.1158/1538-7445.AM10-2500

Published: 15 April 2010

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Journal Articles

Abstract 2766: Multicenter pharmacokinetic evaluation of ON 01910. Na, a novel broad-spectrum anticancer agent, in Phase I single agent clinical trials in patients with solid tumors

Manoj Maniar, Sridhar Mani, Mohammed H. Ghalib, John Roboz, Takao Ohnuma, Suresh Advani, Raghunadh Rao, D Doval, Manmohan Acharya, Edward O'Rourke, Francois Wilhelm, James F. Holland, David Taft

Cancer Res (2010) 70 (8_Supplement): 2766.

DOI: https://doi.org/10.1158/1538-7445.AM10-2766

Published: 15 April 2010

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Journal Articles

Abstract #3866: Modulation of Chk1, Chk2, p-Chk2 dimer and p-ATM in cancer cells treated with ON 01910.Na, a clinical stage mitotic inhibitor

Irina Oussenko, James F. Holland, E. Premkumar Reddy, Takao Ohnuma

Cancer Res (2009) 69 (9_Supplement): 3866.

Published: 01 May 2009

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Journal Articles

Combination of ON 01910.Na and Oxaliplatin against DU-145 human prostate carcinoma and Bel7404 hepatoma cells in vitro

Irina Oussenko, Takao Ohnuma, Jian-Dong Jiang, E. Premkumar Reddy, James F. Holland

Cancer Res (2008) 68 (9_Supplement): 654.

Published: 01 May 2008

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Journal Articles

Characterization of Viral Particles Isolated from Primary Cultures of Human Breast Cancer Cells

Stella M. Melana, Irene Nepomnaschy, Michael Sakalian, Andrea Abbott, Jennifer Hasa, James F. Holland, Beatriz G.T. Pogo

Cancer Res (2007) 67 (18): 8960–8965.

DOI: https://doi.org/10.1158/0008-5472.CAN-06-3892

Published: 17 September 2007

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Includes: Supplementary data

Journal Articles

Toxicology of a novel small molecule ON1910Na on human bone marrow and leukemic cells in vitro

Igor Skidan, Svetlana Zinzar, James F. Holland, Ramana Reddy, E. P. Reddy, Lewis R. Silverman

Cancer Res (2006) 66 (8_Supplement): 309.

Published: 15 April 2006

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Journal Articles

PAR, a putative chromosomal passenger protein involved in cell cycle

Desmond N. Jackson, Alin Ionescu, Elena Ivan, James F. Holland, Micsumica Platica, Ovidiu Platica

Cancer Res (2006) 66 (8_Supplement): 1153–1154.

Published: 15 April 2006

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2 3 4 5

NARROW

Abstract 5757: Study of human mammary tumor virus (HMTV) in human breast cancer by NanoString nCounter and FISH analysis

Abstract 4062: Human mammary tumor virus (HMTV) is a breast cancer pathogen

Abstract 694: Structure-function analysis of RPL18A, a putative binding target of rigosertib

Abstract 821: Human mammary tumor virus(HMTV) is deeply involved in breast cancer and metastasis

Abstract 4595: RPL18A as putative target of rigosertib

Abstract 1595: Human mammary tumor virus (HMTV) detection in surgical specimens and metastases of human breast cancer by the Nanostring nCounter system and FISH analysis

Abstract 3797: Hyperphosphorylation and desumoylation of RanGAP1·SUMO1

Abstract 2675: CXCL12 (SDF-1) and its truncation products in patients with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) receiving ON 01910.Na (Rigosertib) in phase I trials

Abstract 5751: Detection of HMTV in breast and endometrium carcinomas

Effect of ON 01910.Na, an Anticancer Mitotic Inhibitor, on Cell-Cycle Progression Correlates with RanGAP1 Hyperphosphorylation

Abstract 2723: Host response to HMTV

Abstract 2639: RanGAP1·SUMO1 hyperphosphorylation (RGSH) and mitotic arrest by ON 01910.Na, okadaic acid or tubulin agents

Abstract 2302: Detection of HMTV env sequences in hormonally dependent tissues

Abstract 2500: ON 01910. Na, a clinical stage anticancer mitotic inhibitor, produces prolonged hyperphosphorylation of RanGAP1•SUMO1 as a potential mechanism of G2/M arrest and apoptosis

Abstract 2766: Multicenter pharmacokinetic evaluation of ON 01910. Na, a novel broad-spectrum anticancer agent, in Phase I single agent clinical trials in patients with solid tumors

Abstract #3866: Modulation of Chk1, Chk2, p-Chk2 dimer and p-ATM in cancer cells treated with ON 01910.Na, a clinical stage mitotic inhibitor

Combination of ON 01910.Na and Oxaliplatin against DU-145 human prostate carcinoma and Bel7404 hepatoma cells in vitro

Characterization of Viral Particles Isolated from Primary Cultures of Human Breast Cancer Cells

Toxicology of a novel small molecule ON1910Na on human bone marrow and leukemic cells in vitro

PAR, a putative chromosomal passenger protein involved in cell cycle

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