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Abstract 6248: Inhibiting β-catenin in AML by targeting DDX5

WEI NI, Swati Garg, Fen Zhu, Ellen L. Weisberg, Basudev Chowdhury, Martin Sattler, Amulya Jakkani, Suiyang Liu, Dana M. Sanchez, Lizi Wu, Richard M. Stone, Matthew S. Davids, James D. Griffin

Cancer Res (2023) 83 (7_Supplement): 6248.

https://doi.org/10.1158/1538-7445.AM2023-6248

Published: 04 April 2023

View articletitled, Abstract 6248: Inhibiting β-catenin in AML by targeting DDX5

Journal Articles

Abstract 3972: MicroRNAs as potential therapeutic agents for AML: Targeting the AML1-ETO Oncogene by pre-miR-520 and -373

Patricia A. Toniolo, Patrick M. Pilarski, Christian Bach, James D. Griffin, Sophia Adamia

Cancer Res (2015) 75 (15_Supplement): 3972.

https://doi.org/10.1158/1538-7445.AM2015-3972

Published: 01 August 2015

View articletitled, Abstract 3972: MicroRNAs as potential therapeutic agents for AML: Targeting the AML1-ETO Oncogene by pre-miR-520 and -373

Journal Articles

Abstract 3026: Targeting aberrantly activated AREG-EGFR signaling in CRTC1-MAML2-positive mucoepidermoid carcinoma.

Zirong Chen, Yumei Gu, Chengbin Hu, Jian-Liang Li, Shuibin Lin, Huangxuan Shen, Chunxia Cao, Jie Chen, Jiancheng Li, Patick K. Ha, Federic J. Kaye, James D. Griffin, Lizi Wu

Cancer Res (2013) 73 (8_Supplement): 3026.

https://doi.org/10.1158/1538-7445.AM2013-3026

Published: 15 April 2013

View articletitled, Abstract 3026: Targeting aberrantly activated AREG-EGFR signaling in CRTC1-MAML2-positive mucoepidermoid carcinoma.

Journal Articles

Abstract #3395: Phosphoproteomics analysis reveals distinct tyrosine phosphorylation patterns between the ITD and D835Y mutant FLT3 tyrosine kinase receptors

Jingrui Jiang, Yi Zhang, Manor Askenazi, Jarrod A. Marto, James D. Griffin

Cancer Res (2009) 69 (9_Supplement): 3395.

Published: 01 May 2009

View articletitled, Abstract #3395: Phosphoproteomics analysis reveals distinct tyrosine phosphorylation patterns between the ITD and D835Y mutant FLT3 tyrosine kinase receptors

Journal Articles

Y572 is a functionally important amino acid for autoinhibition of the FLT3 receptor tyrosine kinase

Jingrui Jiang, James D. Griffin

Cancer Res (2006) 66 (8_Supplement): 344.

Published: 15 April 2006

View articletitled, Y572 is a functionally important amino acid for autoinhibition of the FLT3 receptor tyrosine kinase

Journal Articles

Epidermal Growth Factor–Independent Transformation of Ba/F3 Cells with Cancer-Derived Epidermal Growth Factor Receptor Mutants Induces Gefitinib-Sensitive Cell Cycle Progression

Jingrui Jiang, Heidi Greulich, Pasi A. Jänne, William R. Sellers, Matthew Meyerson, James D. Griffin

Cancer Res (2005) 65 (19): 8968–8974.

https://doi.org/10.1158/0008-5472.CAN-05-1829

Published: 03 October 2005

View articletitled, Epidermal Growth Factor–Independent Transformation of Ba/F3 Cells with Cancer-Derived Epidermal Growth Factor Receptor Mutants Induces Gefitinib-Sensitive Cell Cycle Progression

Journal Articles

Transforming activity of the MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation

Lizi Wu, Jingxuan Liu, Ping Gao, Makoto Nakamura, James D. Griffin

Cancer Res (2005) 65 (9_Supplement): 610.

Published: 01 May 2005

View articletitled, Transforming activity of the MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation

Journal Articles

Identification and characterization of a novel activating mutation in the extracellular domain of the FLT3 tyrosine kinase in ALL

Jingrui Jiang, J. Guillermo Paez, Jeffrey C. Lee, Sabina Chiaretti, Robin Foa, Jerome Ritz, Gary Gilliland, William R. Sellers, Matthew Meyerson, James D. Griffin

Cancer Res (2005) 65 (9_Supplement): 1059.

Published: 01 May 2005

View articletitled, Identification and characterization of a novel activating mutation in the extracellular domain of the FLT3 tyrosine kinase in ALL

Journal Articles

Pharmacological profile of the FLT3-Tyrosine Kinase Inhibitor AST487

Johannes L. Roesel, Guido Bold, Josef Brueggen, Doriano Fabbro, Andreas Floersheimer, Michael Jensen-Rugaard, Stefan Ruetz, Ellen Weisberg, James D. Griffin, Florian Heidel, Thomas Fischer

Cancer Res (2005) 65 (9_Supplement): 1409.

Published: 01 May 2005

View articletitled, Pharmacological profile of the FLT3-Tyrosine Kinase Inhibitor AST487

Journal Articles

AMN107: Inhibitory profile against non-mutated and mutated forms of the Bcr-Abl tyrosine kinase

Paul W. Manley, Jürgen Mestan, Sandra Cowan-Jacob, Markus Wartmann, Ellen Weisberg, Doriano Fabbro, D. Gary Gilliland, James D. Griffin

Cancer Res (2005) 65 (9_Supplement): 1408.

Published: 01 May 2005

View articletitled, AMN107: Inhibitory profile against non-mutated and mutated forms of the Bcr-Abl tyrosine kinase

Journal Articles

Prediction of Resistance to Small Molecule FLT3 Inhibitors: Implications for Molecularly Targeted Therapy of Acute Leukemia

Jan Cools, Nicole Mentens, Pascal Furet, Doriano Fabbro, Jennifer J. Clark, James D. Griffin, Peter Marynen, D. Gary Gilliland

Cancer Res (2004) 64 (18): 6385–6389.

https://doi.org/10.1158/0008-5472.CAN-04-2148

Published: 16 September 2004

View articletitled, Prediction of Resistance to Small Molecule FLT3 Inhibitors: Implications for Molecularly Targeted Therapy of Acute Leukemia

Journal Articles

E6 oncoproteins interact with mastermind-like transcriptional co-activators and alter Notch signaling

Lizi Wu, Ping Gao, Jingxuan Liu, James D. Griffin

Cancer Res (2004) 64 (7_Supplement): 1276.

Published: 01 April 2004

View articletitled, E6 oncoproteins interact with mastermind-like transcriptional co-activators and alter Notch signaling

Journal Articles

c-MET Mutational Analysis in Small Cell Lung Cancer: Novel Juxtamembrane Domain Mutations Regulating Cytoskeletal Functions

Patrick C. Ma, Takashi Kijima, Gautam Maulik, Edward A. Fox, Martin Sattler, James D. Griffin, Bruce E. Johnson, Ravi Salgia

Cancer Res (2003) 63 (19): 6272–6281.

Published: 14 October 2003

View articletitled, c-MET Mutational Analysis in Small Cell Lung Cancer: Novel Juxtamembrane Domain Mutations Regulating Cytoskeletal Functions

Journal Articles

The Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor PTK787/ZK222584 Inhibits Growth and Migration of Multiple Myeloma Cells in the Bone Marrow Microenvironment

Boris Lin, Klaus Podar, Deepak Gupta, Yu-Tzu Tai, Sigui Li, Edie Weller, Teru Hideshima, Suzanne Lentzsch, Faith Davies, Cheng Li, Ellen Weisberg, Robert L. Schlossman, Paul G. Richardson, James D. Griffin, Jeanette Wood, Nikhil C. Munshi, Kenneth C. Anderson

Cancer Res (2002) 62 (17): 5019–5026.

Published: 01 September 2002

View articletitled, The Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor PTK787/ZK222584 Inhibits Growth and Migration of Multiple Myeloma Cells in the Bone Marrow Microenvironment

Journal Articles

Surface Immunoglobulin-mediated Signal Transduction Involves Rapid Phosphorylation and Activation of the Protooncogene Product Raf-1 in Human B-Cells

Toshiharu Tamaki, Yuzuru Kanakura, Akira Kuriu, Hirokazu Ikeda, Hideki Mitsui, Hirosuke Yagura, Itaru Matsumura, Brian Druker, James D. Griffin, Yoshio Kanayama, Takeshi Yonezawa

Cancer Res (1992) 52 (3): 566–570.

Published: 01 February 1992

View articletitled, Surface Immunoglobulin-mediated Signal Transduction Involves Rapid Phosphorylation and Activation of the Protooncogene Product Raf-1 in Human B-Cells

Journal Articles

Selective Cytotoxicity of the SM1 Monoclonal Antibody towards Small Cell Carcinoma of the Lung

Samuel D. Bernal, Mack Mabry, Rolf A. Stahel, James D. Griffin, Jonathan A. Speak

Cancer Res (1985) 45 (3): 1026–1032.

Published: 01 March 1985

View articletitled, Selective Cytotoxicity of the SM1 Monoclonal Antibody towards Small Cell Carcinoma of the Lung

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Abstract 6248: Inhibiting β-catenin in AML by targeting DDX5

Abstract 3972: MicroRNAs as potential therapeutic agents for AML: Targeting the AML1-ETO Oncogene by pre-miR-520 and -373

Abstract 3026: Targeting aberrantly activated AREG-EGFR signaling in CRTC1-MAML2-positive mucoepidermoid carcinoma.

Abstract #3395: Phosphoproteomics analysis reveals distinct tyrosine phosphorylation patterns between the ITD and D835Y mutant FLT3 tyrosine kinase receptors

Y572 is a functionally important amino acid for autoinhibition of the FLT3 receptor tyrosine kinase

Epidermal Growth Factor–Independent Transformation of Ba/F3 Cells with Cancer-Derived Epidermal Growth Factor Receptor Mutants Induces Gefitinib-Sensitive Cell Cycle Progression

Transforming activity of the MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation

Identification and characterization of a novel activating mutation in the extracellular domain of the FLT3 tyrosine kinase in ALL

Pharmacological profile of the FLT3-Tyrosine Kinase Inhibitor AST487

AMN107: Inhibitory profile against non-mutated and mutated forms of the Bcr-Abl tyrosine kinase

Prediction of Resistance to Small Molecule FLT3 Inhibitors: Implications for Molecularly Targeted Therapy of Acute Leukemia

E6 oncoproteins interact with mastermind-like transcriptional co-activators and alter Notch signaling

c-MET Mutational Analysis in Small Cell Lung Cancer: Novel Juxtamembrane Domain Mutations Regulating Cytoskeletal Functions

The Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor PTK787/ZK222584 Inhibits Growth and Migration of Multiple Myeloma Cells in the Bone Marrow Microenvironment

Surface Immunoglobulin-mediated Signal Transduction Involves Rapid Phosphorylation and Activation of the Protooncogene Product Raf-1 in Human B-Cells

Selective Cytotoxicity of the SM1 Monoclonal Antibody towards Small Cell Carcinoma of the Lung

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