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James C. Cusack
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Journal Articles

Abstract 1914: Potent anticancer activity against both BRAF-mutant and BRAF wild-type melanoma cell lines using a novel CRM1 nuclear export inhibitor

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Roberto A. Salas Fragomeni, Hye-Won Chung, Sharon Shacham, Michael Kauffman, James C. Cusack
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1914.
https://doi.org/10.1158/1538-7445.AM2012-1914
Published: 15 April 2012
View articletitled, Abstract 1914: Potent anticancer activity against both BRAF-mutant and BRAF wild-type melanoma cell lines using a novel CRM1 nuclear export inhibitor
Journal Articles

Abstract 2129: HB-EGF expression in gastric cancer promotes chemotherapy resistance and represents a promising target for molecular therapy and a novel biomarker of 5-FU resistance

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Juan A. Santamaria-Barria, Callum M. Sloss, James C. Cusack
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2129.
https://doi.org/10.1158/1538-7445.AM2011-2129
Published: 15 April 2011
View articletitled, Abstract 2129: HB-EGF expression in gastric cancer promotes chemotherapy resistance and represents a promising target for molecular therapy and a novel biomarker of 5-FU resistance
Journal Articles

Abstract 2210: Activation of PI3K in Merkel cell carcinoma

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Valentina Nardi, Young Chul Song, Arjola K. Cosper, Quynh Lam, Juan Antonio Santamaria Barria, Genevieve Marie Boland, Beow Yeap, Kristin Bergethon, Vanessa L. Scialabba, Jeffrey Settleman, David P. Ryan, Darrell R. Borger, Mai P. Hoang, Atul K. Bhan, Anthony J. Iafrate, James C. Cusack, Jeffrey A. Engelman, Dora Dias-Santagata
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2210.
https://doi.org/10.1158/1538-7445.AM2011-2210
Published: 15 April 2011
View articletitled, Abstract 2210: Activation of PI3K in Merkel cell carcinoma
Journal Articles

Membrane-Bound Heparin-Binding Epidermal Growth Factor–Like Growth Factor Regulates E-Cadherin Expression in Pancreatic Carcinoma Cells

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Fang Wang, Callum Sloss, Xiaobo Zhang, Sam W. Lee, James C. Cusack
Journal: Cancer Research
Cancer Res (2007) 67 (18): 8486–8493.
https://doi.org/10.1158/0008-5472.CAN-07-0498
Published: 17 September 2007
View articletitled, Membrane-Bound Heparin-Binding Epidermal Growth Factor–Like Growth Factor Regulates E-Cadherin Expression in Pancreatic Carcinoma Cells
Open the PDF for Membrane-Bound Heparin-Binding Epidermal Growth Factor–Like Growth Factor Regulates E-Cadherin Expression in Pancreatic Carcinoma Cells in another window
Journal Articles

Modulation of EGFR and MAPK pathways by HB-EGF in response to chemotherapy is induced by NF-κB activation

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Fang Wang, Rong Liu, Sam W. Lee, Jennifer Jennifer Couget, James C. Cusack, Jr
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 300.
Published: 15 April 2006
View articletitled, Modulation of EGFR and MAPK pathways by HB-EGF in response to chemotherapy is induced by NF-κB activation
Journal Articles

Oral proteasome inhibitor (NPI-0052) enhances sensitivity to combination Gemcitabine and Erbitux in a pancreatic cancer xenograft model

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James C. Cusack, Jr, Rong Liu, Lijun Xia, David Ljungman, Rena Bahjat, Michael A. Palladino, Jr
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1167.
Published: 01 May 2005
View articletitled, Oral proteasome inhibitor (NPI-0052) enhances sensitivity to combination Gemcitabine and Erbitux in a pancreatic cancer xenograft model
Journal Articles

Drug resistance in a sarcoma xenograft model is overcome by schedule-dependent proteasome inhibition using Velcade™ (Bortezomib, formerly PS-341).

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David Ljungman, John Flannery, Rong Liu, Lijun Xia, Julian Adams, Peter Elliott, Margaret Read, Oscar Kashala, James C. Cusack
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 491.
Published: 01 April 2004
View articletitled, Drug resistance in a sarcoma xenograft model is overcome by schedule-dependent proteasome inhibition using Velcade™ (Bortezomib, formerly PS-341).
Journal Articles

Enhanced Chemosensitivity to CPT-11 with Proteasome Inhibitor PS-341:: Implications for Systemic Nuclear Factor-κB Inhibition

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James C. Cusack, Jr., Rong Liu, Michael Houston, Karin Abendroth, Peter J. Elliott, Julian Adams, Albert S. Baldwin, Jr.
Journal: Cancer Research
Cancer Res (2001) 61 (9): 3535–3540.
Published: 01 May 2001
View articletitled, Enhanced Chemosensitivity to CPT-11 with Proteasome Inhibitor PS-341:: Implications for Systemic Nuclear Factor-κB Inhibition
Open the PDF for Enhanced Chemosensitivity to CPT-11 with Proteasome Inhibitor PS-341:: Implications for Systemic Nuclear Factor-κB Inhibition in another window
Journal Articles

Inducible Chemoresistance to 7-Ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) in Colorectal Cancer Cells and a Xenograft Model Is Overcome by Inhibition of Nuclear Factor-κB Activation

Free
James C. Cusack, Jr., Rong Liu, Albert S. Baldwin, Jr.
Journal: Cancer Research
Cancer Res (2000) 60 (9): 2323–2330.
Published: 01 May 2000
View articletitled, Inducible Chemoresistance to 7-Ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) in Colorectal Cancer Cells and a Xenograft Model Is Overcome by Inhibition of Nuclear Factor-κB Activation
Open the PDF for Inducible Chemoresistance to 7-Ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) in Colorectal Cancer Cells and a Xenograft Model Is Overcome by Inhibition of Nuclear Factor-κB Activation in another window
Journal Articles

Expression of Human α(1,3)Fucosyltransferase Antisense Sequences Inhibits Selectin-mediated Adhesion and Liver Metastasis of Colon Carcinoma Cells

Free
Brent W. Weston, Kara M. Hiller, John P. Mayben, George A. Manousos, Katharine M. Bendt, Rong Liu, James C. Cusack, Jr.
Journal: Cancer Research
Cancer Res (1999) 59 (9): 2127–2135.
Published: 01 May 1999
View articletitled, Expression of Human α(1,3)Fucosyltransferase Antisense Sequences Inhibits Selectin-mediated Adhesion and Liver Metastasis of Colon Carcinoma Cells
Open the PDF for Expression of Human α(1,3)Fucosyltransferase Antisense Sequences Inhibits Selectin-mediated Adhesion and Liver Metastasis of Colon Carcinoma Cells in another window