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James Barsoum
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Journal Articles

Abstract 1282: Phase I evaluation of STA-1474, a pro-drug of the novel HSP90 inhibitor STA-9090, in dogs with spontaneous cancer

Cheryl A. London, Misty D. Bear, Jennifer McCleese, Kevin P. Foley, Reji Paalangara, Takayo Inoue, Weiwen Ying, James Barsoum
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1282.
https://doi.org/10.1158/1538-7445.AM2011-1282
Published: 15 April 2011
View article titled, Abstract 1282: Phase I evaluation of STA-1474, a pro-drug of the novel HSP90 inhibitor STA-9090, in dogs with spontaneous cancer
Journal Articles

Abstract #4679: The novel Hsp90 inhibitor STA-9090 has potent anticancer activity in in vitro and in vivo models of lung cancer

Takeshi Shimamura, Christa Borgman, Liang Chen, Danan Li, Kevin Foley, Jim Sang, Matthew Meyerson, Weiwen Ying, James Barsoum, Kwok-Kin Wong, Geoffrey Shapiro
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4679.
Published: 01 May 2009
View article titled, Abstract #4679: The novel Hsp90 inhibitor STA-9090 has potent anticancer activity in <em>in vitro</em> and <em>in vivo</em> models of lung cancer
Journal Articles

Abstract #4579: Elesclomol and chemotherapy agents synergistically induce apoptosis in breast cancer cells

Ying Qu, Jinhua Wang, Bingya Liu, Armando Giuliano, James Barsoum, Xiaojiang Cui
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4579.
Published: 01 May 2009
View article titled, Abstract #4579: Elesclomol and chemotherapy agents synergistically induce apoptosis in breast cancer cells
Journal Articles

Elesclomol (formerly STA-4783) induces oxidative stress selectively in cancer cells and inhibits tumor growth independent of immune status

John Bertin, Irma Allen, Vish Balasubramanyam, Kwan Chan, Zhenjian Du, Suqin He, Amy Hutchings, Takayo Inoue, Jane Kepros, Jessica Kirshner, Timothy Korbut, Robert Mihalek, Patricia Rao, Jim Sang, Don Smith, Noriaki Tatsuta, Chin-Yu Yang, Chaohua Zhang, Haili Zhang, Mei Zhang, Dan Zhou, James Barsoum, Kevin Foley
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3300.
Published: 01 May 2008
View article titled, Elesclomol (formerly STA-4783) induces oxidative stress selectively in cancer cells and inhibits tumor growth independent of immune status
Journal Articles

Vascular disrupting agent STA-9584 selectively targets microvasculature at both the center and periphery of tumors

Kevin Foley, Christopher Borella, Kwan Chan, Zhenjian Du, Todd Goodrich, Takayo Inoue, Eita Kitayama, Timothy Korbut, Robert Mihalek, Jim Sang, Don Smith, Andrew Sonderfan, Wenping Song, Yaming Wu, Chin-Yu Yang, Josephine Ye, Chaohua Zhang, Haili Zhang, Mei Zhang, Xuemei Zhang, Dan Zhou, James Barsoum
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1444.
Published: 01 May 2008
View article titled, Vascular disrupting agent STA-9584 selectively targets microvasculature at both the center and periphery of tumors
Journal Articles

Pre-clinical toxicology evaluation of STA-4783 alone or in combination with paclitaxel in rats, mice, and dogs.

Dan Zhou, Marie E. McKeon, Thomas A. Dahl, Eita Kitayama, Noriaki Tastuta, Lijun Sun, Mitsunori Ono, Long Li, James Barsoum, Shelley Mendenhall, Keizo Koya
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 486.
Published: 01 April 2004
View article titled, Pre-clinical toxicology evaluation of STA-4783 alone or in combination with paclitaxel in rats, mice, and dogs.
Journal Articles

STA-4783, a novel HSP70 inducer, enhances the anti-cancer activity of Paclitaxel without increasing toxicity in preclinical studies

Keizo Koya, Lijun Sun, Shoujun Chen, Noriaki Tatsuta, Timothy Korbut, Dan Zhou, Guiqing Liang, Yaming Wu, Zhenjian Du, Zhi-Qiang Xia, Thomas A. Dahl, James Barsoum, Mitsunori Ono, Lan Bo Chen
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 346.
Published: 01 April 2004
View article titled, STA-4783, a novel HSP70 inducer, enhances the anti-cancer activity of Paclitaxel without increasing toxicity in preclinical studies
Journal Articles

STA-5312, a novel tubulin inhibitor, demonstrates the anti-cancer activity against chemotherapy-resistant cancers

Keizo Koya, Lijun Sun, Hao Li, David James, Noriaki Tatsuta, Timothy Korbut, Dan Zhou, Guiqing Liang, Yaming Wu, Zhenjian Du, Shoujun Chen, James Barsoum, Thomas A. Dahl, Mitsunori Ono, Lan Bo Chen
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1250.
Published: 01 April 2004
View article titled, STA-5312, a novel tubulin inhibitor, demonstrates the anti-cancer activity against chemotherapy-resistant cancers
Journal Articles

Stat1-dependent Induction of Tumor Necrosis Factor-related Apoptosis-inducing Ligand and the Cell-Surface Death Signaling Pathway by Interferon β in Human Cancer Cells

Eugene A. Choi, Hanqin Lei, David J. Maron, James M. Wilson, James Barsoum, Douglas L. Fraker, Wafik S. El-Deiry, Francis R. Spitz
Journal: Cancer Research
Cancer Res (2003) 63 (17): 5299–5307.
Published: 18 September 2003
View article titled, Stat1-dependent Induction of Tumor Necrosis Factor-related Apoptosis-inducing Ligand and the Cell-Surface Death Signaling Pathway by Interferon β in Human Cancer Cells
Open the PDF for Stat1-dependent Induction of Tumor Necrosis Factor-related Apoptosis-inducing Ligand and the Cell-Surface Death Signaling Pathway by Interferon β in Human Cancer Cells in another window
Journal Articles

Eradication of Intraperitoneal and Distant Tumor by Adenovirus-mediated Interferon-β Gene Therapy Is Attributable to Induction of Systemic Immunity

Makoto Odaka, Daniel H. Sterman, Rainer Wiewrodt, Yi Zhang, Michael Kiefer, Kunjlata M. Amin, Guan-Ping Gao, James M. Wilson, James Barsoum, Larry R. Kaiser, Steven M. Albelda
Journal: Cancer Research
Cancer Res (2001) 61 (16): 6201–6212.
Published: 01 August 2001
View article titled, Eradication of Intraperitoneal and Distant Tumor by Adenovirus-mediated Interferon-β Gene Therapy Is Attributable to Induction of Systemic Immunity
Open the PDF for Eradication of Intraperitoneal and Distant Tumor by Adenovirus-mediated Interferon-β Gene Therapy Is Attributable to Induction of Systemic Immunity in another window