1-20 of 69
James B. Mitchell
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract 2837: Conservation of JAK-STAT signaling in canine lymphocytes responding to human IL-6, IL-7, and IL-1 alpha

King Leung Fung, Melissa L. Breiner, James B. Mitchell, Ralph E. Parchment
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2837.
https://doi.org/10.1158/1538-7445.AM2024-2837
Published: 22 March 2024
View article titled, Abstract 2837: Conservation of JAK-STAT signaling in canine lymphocytes responding to human IL-6, IL-7, and IL-1 alpha
Journal Articles

Multimodal Molecular Imaging Detects Early Responses to Immune Checkpoint Blockade

Yu Saida, Jeffrey R. Brender, Kazutoshi Yamamoto, James B. Mitchell, Murali C. Krishna, Shun Kishimoto
Journal: Cancer Research
Cancer Res (2021) 81 (13): 3693–3705.
https://doi.org/10.1158/0008-5472.CAN-20-3182
Published: 01 July 2021
View article titled, Multimodal Molecular Imaging Detects Early Responses to Immune Checkpoint Blockade
Open the PDF for Multimodal Molecular Imaging Detects Early Responses to Immune Checkpoint Blockade in another window
Includes: Supplementary data
Journal Articles

Molecular Imaging of the Tumor Microenvironment Reveals the Relationship between Tumor Oxygenation, Glucose Uptake, and Glycolysis in Pancreatic Ductal Adenocarcinoma

Kazutoshi Yamamoto, Jeffrey R. Brender, Tomohiro Seki, Shun Kishimoto, Nobu Oshima, Rajani Choudhuri, Stephen S. Adler, Elaine M. Jagoda, Keita Saito, Nallathamby Devasahayam, Peter L. Choyke, James B. Mitchell, Murali C. Krishna
Journal: Cancer Research
Cancer Res (2020) 80 (11): 2087–2093.
https://doi.org/10.1158/0008-5472.CAN-19-0928
Published: 02 June 2020
View article titled, Molecular Imaging of the Tumor Microenvironment Reveals the Relationship between Tumor Oxygenation, Glucose Uptake, and Glycolysis in Pancreatic Ductal Adenocarcinoma
Open the PDF for Molecular Imaging of the Tumor Microenvironment Reveals the Relationship between Tumor Oxygenation, Glucose Uptake, and Glycolysis in Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 3587: Targeting cancer metabolism: A novel approach for improved radiotherapy

Suchet Taori, Sarwat Naz, Janet Gamson, Askale Mathias, John Cook, James B. Mitchell
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3587.
https://doi.org/10.1158/1538-7445.AM2019-3587
Published: 01 July 2019
View article titled, Abstract 3587: Targeting cancer metabolism: A novel approach for improved radiotherapy
Journal Articles

A Multimodal Molecular Imaging Study Evaluates Pharmacological Alteration of the Tumor Microenvironment to Improve Radiation Response

Yoichi Takakusagi, Sarwat Naz, Kaori Takakusagi, Masahiro Ishima, Hiroshi Murata, Keisuke Ohta, Masahiko Miura, Fumio Sugawara, Kengo Sakaguchi, Shun Kishimoto, Jeeva P. Munasinghe, James B. Mitchell, Murali C. Krishna
Journal: Cancer Research
Cancer Res (2018) 78 (24): 6828–6837.
https://doi.org/10.1158/0008-5472.CAN-18-1654
Published: 13 December 2018
View article titled, A Multimodal Molecular Imaging Study Evaluates Pharmacological Alteration of the Tumor Microenvironment to Improve Radiation Response
Open the PDF for A Multimodal Molecular Imaging Study Evaluates Pharmacological Alteration of the Tumor Microenvironment to Improve Radiation Response in another window
Journal Articles

Metabolic and Physiologic Imaging Biomarkers of the Tumor Microenvironment Predict Treatment Outcome with Radiation or a Hypoxia-Activated Prodrug in Mice

Shingo Matsumoto, Shun Kishimoto, Keita Saito, Yoichi Takakusagi, Jeeva P. Munasinghe, Nallathamby Devasahayam, Charles P. Hart, Robert J. Gillies, James B. Mitchell, Murali C. Krishna
Journal: Cancer Research
Cancer Res (2018) 78 (14): 3783–3792.
https://doi.org/10.1158/0008-5472.CAN-18-0491
Published: 15 July 2018
View article titled, Metabolic and Physiologic Imaging Biomarkers of the Tumor Microenvironment Predict Treatment Outcome with Radiation or a Hypoxia-Activated Prodrug in Mice
Open the PDF for Metabolic and Physiologic Imaging Biomarkers of the Tumor Microenvironment Predict Treatment Outcome with Radiation or a Hypoxia-Activated Prodrug in Mice in another window
Includes: Supplementary data
Journal Articles

Abstract 4104: Evaluation of a novel LDH inhibitor efficacy in vivo in a glycolytic cancer model using hyperpolarized 13C magnetic resonance imaging

Nobu Oshima, Shun Kishimoto, Kristin Beebe, Dan Crooks, Michael Moses, Kazutoshi Yamamoto, Jeffry R. Brender, Anastasia Sowers, Ganesha Rai, Daniel Urban, Goria Benavides, Giuseppe Squadrito, Victor Darley-Usmar, Matthew Hall, James B. Mitchell, Murali C. Krishna, Leonard M. Neckers
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4104.
https://doi.org/10.1158/1538-7445.AM2018-4104
Published: 01 July 2018
View article titled, Abstract 4104: Evaluation of a novel LDH inhibitor efficacy in vivo in a glycolytic cancer model using hyperpolarized <sup>13</sup>C magnetic resonance imaging
Journal Articles

Abstract 4106: Hyperpolarized [1-13C]-pyruvate/lactate magnetic resonance spectroscopic imaging of prostate cancer in vivo predicts response to lactate dehydrogenase inhibition

Bradley T. Scroggins, Masayuki Matsuo, Ayla O. White, Keita Saito, Jeeva P. Munasinghe, Carole Sourbier, Kazutoshi Yamamoto, Vivian Diaz, James B. Mitchell, Murali C. Krishna, Deborah E. Citrin
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4106.
https://doi.org/10.1158/1538-7445.AM2018-4106
Published: 01 July 2018
View article titled, Abstract 4106: Hyperpolarized [1-<sup>13</sup>C]-pyruvate/lactate magnetic resonance spectroscopic imaging of prostate cancer in vivo predicts response to lactate dehydrogenase inhibition
Journal Articles

Abstract 5861: Enhanced radiosenistivity of EGFR-TKI sensitive and resistant NSCLC cells by abemaciclib is mediated by altered DNA repair and metabolic pathways

Sarwat Naz, William DeGraff, Anastasia Sowers, Rajani Choudhuri, Maria Wissler, Janet Gamson, John Cook, James B. Mitchell
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5861.
https://doi.org/10.1158/1538-7445.AM2017-5861
Published: 01 July 2017
View article titled, Abstract 5861: Enhanced radiosenistivity of EGFR-TKI sensitive and resistant NSCLC cells by abemaciclib is mediated by altered DNA repair and metabolic pathways
Journal Articles

Abstract 833: Alginate hydrogels for three-dimensional culture and real-time monitoring of cancer cell metabolism and radiation response

Aparna H. Kesarwala, Jenna L. Carter, Graham H. Read, Natsuko Miura, Kazutoshi Yamamoto, James B. Mitchell, Murali C. Krishna
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 833.
https://doi.org/10.1158/1538-7445.AM2017-833
Published: 01 July 2017
View article titled, Abstract 833: Alginate hydrogels for three-dimensional culture and real-time monitoring of cancer cell metabolism and radiation response
Journal Articles

Abstract 1696: High-dose versus low-dose fractionated ionizing radiation to enhance antigen-specific antitumor immunity

Megan V. Morisada, Ellen C. Moore, Jay A. Friedman, James W. Hodge, James B. Mitchell, Clint T. Allen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1696.
https://doi.org/10.1158/1538-7445.AM2017-1696
Published: 01 July 2017
View article titled, Abstract 1696: High-dose versus low-dose fractionated ionizing radiation to enhance antigen-specific antitumor immunity
Journal Articles

Abstract 2852: Monitoring the impact on metabolic flux in vivo of a newly developed LDH inhibitor using hyperpolarized 13C magnetic resonance spectroscopic imaging

Nobu Oshima, Shun Kishimoto, Kristin Beebe, Keita Saito, Kazutoshi Yamamoto, Jeffery Brender, Anastasia Sowers, Ganesha Rai, Bryan T. Mott, David J. Maloney, James B. Mitchell, Murali K. Cherukuri, Leonard M. Neckers
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2852.
https://doi.org/10.1158/1538-7445.AM2017-2852
Published: 01 July 2017
View article titled, Abstract 2852: Monitoring the impact on metabolic flux <em>in vivo</em> of a newly developed LDH inhibitor using hyperpolarized 13C magnetic resonance spectroscopic imaging
Journal Articles

SMAC Mimetic Birinapant plus Radiation Eradicates Human Head and Neck Cancers with Genomic Amplifications of Cell Death Genes FADD and BIRC2

Danielle F. Eytan, Grace E. Snow, Sophie Carlson, Adeeb Derakhshan, Anthony Saleh, Stephen Schiltz, Hui Cheng, Suresh Mohan, Shaleeka Cornelius, Jamie Coupar, Anastasia L. Sowers, Lidia Hernandez, James B. Mitchell, Christina M. Annunziata, Zhong Chen, Carter Van Waes
Journal: Cancer Research
Cancer Res (2016) 76 (18): 5442–5454.
https://doi.org/10.1158/0008-5472.CAN-15-3317
Published: 15 September 2016
View article titled, SMAC Mimetic Birinapant plus Radiation Eradicates Human Head and Neck Cancers with Genomic Amplifications of Cell Death Genes <em>FADD</em> and <em>BIRC2</em>
Open the PDF for SMAC Mimetic Birinapant plus Radiation Eradicates Human Head and Neck Cancers with Genomic Amplifications of Cell Death Genes <em>FADD</em> and <em>BIRC2</em> in another window
Includes: Supplementary data
Journal Articles

Abstract LB-184: Hyperpolarized 13C-pyruvate magnetic resonance spectroscopic imaging of prostate cancer tumor xenografts

Bradley T. Scroggins, Masayuki Matsuo, Jeeva P. Munasinghe, Ayla O. White, Carole Sourbier, Shingo Matsumoto, W. Marston Linehan, James B. Mitchell, Murali C. Krishna, Deborah E. Citrin
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-184.
https://doi.org/10.1158/1538-7445.AM2016-LB-184
Published: 15 July 2016
View article titled, Abstract LB-184: Hyperpolarized <sup>13</sup>C-pyruvate magnetic resonance spectroscopic imaging of prostate cancer tumor xenografts
Journal Articles

Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer

John A. Cook, Gadisetti V.R. Chandramouli, Miriam R. Anver, Anastasia L. Sowers, Angela Thetford, Kristopher W. Krausz, Frank J. Gonzalez, James B. Mitchell, Andrew D. Patterson
Journal: Cancer Research
Cancer Res (2016) 76 (6): 1569–1577.
https://doi.org/10.1158/0008-5472.CAN-15-2416
Published: 14 March 2016
View article titled, Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer
Open the PDF for Mass Spectrometry–Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer in another window
Includes: Supplementary data
Journal Articles

NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay

Lisa A. Ridnour, Robert Y.S. Cheng, Jonathan M. Weiss, Sukhbir Kaur, David R. Soto-Pantoja, Debashree Basudhar, Julie L. Heinecke, C. Andrew Stewart, William DeGraff, Anastasia L. Sowers, Angela Thetford, Aparna H. Kesarwala, David D. Roberts, Howard A. Young, James B. Mitchell, Giorgio Trinchieri, Robert H. Wiltrout, David A. Wink
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (14): 2788–2799.
https://doi.org/10.1158/0008-5472.CAN-14-3011
Published: 14 July 2015
View article titled, NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay
Open the PDF for NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay in another window
Includes: Supplementary data
Journal Articles

Abstract 2258: Tempol diet provides chemoprotection against UV-induced skin cancer in mice with epidermal Smad4 deletion

Doyel Mitra, Bian Li, Qinghong Zhang, James B. Mitchell, Xiao-Jing Wang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2258.
https://doi.org/10.1158/1538-7445.AM2014-2258
Published: 01 October 2014
View article titled, Abstract 2258: Tempol diet provides chemoprotection against UV-induced skin cancer in mice with epidermal Smad4 deletion
Journal Articles

Abstract CT343: Phase II study of low-dose rate thoracic radiotherapy for treatment of intrathoracic relapsed or progressive small cell lung cancer

Guy C. Jones, James B. Mitchell, Bruce E. Johnson, Kevin Camphausen, Eli Glatstein, Charles B. Simone
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): CT343.
https://doi.org/10.1158/1538-7445.AM2014-CT343
Published: 01 October 2014
View article titled, Abstract CT343: Phase II study of low-dose rate thoracic radiotherapy for treatment of intrathoracic relapsed or progressive small cell lung cancer
Journal Articles

Abstract 1593: Cellular effects of the mitochondrially-directed antioxidant Tempol.

Aparna H. Kesarwala, William DeGraff, Janet Gamson, Rajani Choudhuri, John A. Cook, Murali C. Krishna, James B. Mitchell
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1593.
https://doi.org/10.1158/1538-7445.AM2013-1593
Published: 15 April 2013
View article titled, Abstract 1593: Cellular effects of the mitochondrially-directed antioxidant Tempol.
Journal Articles

The Antioxidant Tempol Reduces Carcinogenesis and Enhances Survival in Mice When Administered after Nonlethal Total Body Radiation

James B. Mitchell, Miriam R. Anver, Anastasia L. Sowers, Philip S. Rosenberg, Maria Figueroa, Angela Thetford, Murali C. Krishna, Paul S. Albert, John A. Cook
Journal: Cancer Research
Cancer Res (2012) 72 (18): 4846–4855.
https://doi.org/10.1158/0008-5472.CAN-12-1879
Published: 16 September 2012
View article titled, The Antioxidant Tempol Reduces Carcinogenesis and Enhances Survival in Mice When Administered after Nonlethal Total Body Radiation
Open the PDF for The Antioxidant Tempol Reduces Carcinogenesis and Enhances Survival in Mice When Administered after Nonlethal Total Body Radiation in another window
Includes: Supplementary data