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James Abbruzzese
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Journal Articles

Abstract B021: Development of an ultrasensitive sequencing platform for blood-based mutation profiling of pancreas cancer patients

Free
Ryne Ramaker, James Abbruzzese, Chris Counter
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): B021.
https://doi.org/10.1158/1538-7445.PANCREATIC24-B021
Published: 15 September 2024
View articletitled, Abstract B021: Development of an ultrasensitive sequencing platform for blood-based mutation profiling of pancreas cancer patients
Journal Articles

Abstract CT145: Olaparib +/- atezolizumab in patients with BRCA-mutated (BRCAmt) locally advanced unresectable or metastatic (advanced) breast cancer: an open-label, multicenter, randomized phase II trial

Free
Kristina A. Fanucci, Mary Jo Pilat, Derek Shyr, Yu Shyr, Scott A. Boerner, Diane Durecki, Anne Noonan, Vandana Abramson, Cesar Santa-Maria, Hyo Han, Rita Nanda, Elizabeth Claire Dees, Haeseong Park, Saundra Buys, Namrata Peswani, Helen Chew, Hadeel Assad, Gerburg Wulf, Angelique Richardson, Meghna S. Trivedi, Adam Brufsky, James Abbruzzese, Anosheh Afghahi, Elad Sharon, Kurt Schalper, Patricia LoRusso
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT145.
https://doi.org/10.1158/1538-7445.AM2023-CT145
Published: 14 April 2023
View articletitled, Abstract CT145: Olaparib +/- atezolizumab in patients with BRCA-mutated (BRCAmt) locally advanced unresectable or metastatic (advanced) breast cancer: an open-label, multicenter, randomized phase II trial
Journal Articles

Abstract 1449: ApoStream™, a new dielectrophoretic device for antibody-independent isolation and recovery of circulating tumor cells from blood of patients with metastatic pancreatic adenocarcinoma.

Free
Gauri Varadhachary, James Abbruzzese, Rachna Shroff, Vladislava Melnikova, Vishal Gupta, Chris Neal, Miguel Garza, David K. Hasegawa, Kenna L. Anderes, Darren Davis, Robert A. Wolff
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1449.
https://doi.org/10.1158/1538-7445.AM2013-1449
Published: 15 April 2013
View articletitled, Abstract 1449: ApoStream™, a new dielectrophoretic device for antibody-independent isolation and recovery of circulating tumor cells from blood of patients with metastatic pancreatic adenocarcinoma.
Journal Articles

Abstract #2718: Molecular profiling of carcinoma of unknown primary and correlation with clinical evaluation

Free
Dmitri Talantov, Gauri Varadhachary, Martin Raber, Timothy Jatkoe, Christina Meng, Kenneth Hess, Renato Lenzi, David Spigel, Anthony Greco, James Abbruzzese, Yixin Wang, John Hainsworth
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2718.
Published: 01 May 2009
View articletitled, Abstract #2718: Molecular profiling of carcinoma of unknown primary and correlation with clinical evaluation
Journal Articles

Abstract #3165: Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of notch signaling pathway

Free
Zhiwei Wang, Yiwei Li, Dejuan Kong, Sanjeev Banerjee, Aamir Ahmad, Asfar Azmi, Shadan Ali, James Abbruzzese, Gary Gallick, Fazlul Sarkar
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3165.
Published: 01 May 2009
View articletitled, Abstract #3165: Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of notch signaling pathway
Journal Articles

Abstract #LB-148: Mast cells in the tumor microenvironment are essential for the tumorigenesis of pancreatic ductal adenocarcinoma (PDAC)

Free
Ying Ma, Baoan Ji, Huamin Wang, Yan Liu, Defeng Deng, Jennifer McQuade, Willem Overwijk, Gregory Lizée, James Abbruzzese, Yong-Jun Liu, Patrick Hwu, Craig Logsdon, Stephen Ullrich, David Chang
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-148.
Published: 01 May 2009
View articletitled, Abstract #LB-148: Mast cells in the tumor microenvironment are essential for the tumorigenesis of pancreatic ductal adenocarcinoma (PDAC)
Journal Articles

Abstract #2139: The association between diabetes mellitus and hepatocellular carcinoma

Free
Manal Hassan, Ahmed Kaseb, Donghui Li, Dalia Moghazy, Jean-Nicolas Vauthey, Steven Curley, Eddie Abdalla, James Abbruzzese
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2139.
Published: 01 May 2009
View articletitled, Abstract #2139: The association between diabetes mellitus and hepatocellular carcinoma
Journal Articles

Abstract #2759: Thymoquinone-induced E2F-1 downregulation and induction of apoptosis enhances gemcitabine effects in pancreatic cancer

Free
Ahmed Kaseb, KB Harikumar, AB Kunnumakkara, A Deorukhkar, James Abbruzzese, Sunil Krishnan, Bharat Aggarwal, Sushovan Guha
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2759.
Published: 01 May 2009
View articletitled, Abstract #2759: Thymoquinone-induced E2F-1 downregulation and induction of apoptosis enhances gemcitabine effects in pancreatic cancer
Journal Articles

Abstract #1613: Overexpression of Axl in pancreatic ductal carcinoma is associated with tumor invasion, metastasis and poor prognosis

Free
Hua Wang, Xianzhou Song, Craig Logsdon, James Abbruzzese, Douglas Evans, Huamin Wang
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1613.
Published: 01 May 2009
View articletitled, Abstract #1613: Overexpression of Axl in pancreatic ductal carcinoma is associated with tumor invasion, metastasis and poor prognosis
Journal Articles

Abstract #4363: Inhibition of mammalian target of rapamycin (mTOR) in advanced pancreatic cancer - the results of two prospective phase II studies.

Free
Milind Javle, Shrikanth Reddy, Darren Davis, Henry Xiong, Gauri Varadhachary, David Fogelman, Ahmed Kaseb, Robert Wolff, James Abbruzzese
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4363.
Published: 01 May 2009
View articletitled, Abstract #4363: Inhibition of mammalian target of rapamycin (mTOR) in advanced pancreatic cancer - the results of two prospective phase II studies.
Journal Articles

Abstract #84: Association of Body Mass Index with Risk, Age of Onset and Survival of Pancreatic Cancer

Free
Donghui Li, jeffrey morris, Jun Liu, Manal Hassan, Rena Day, Melissa Bondy, Douglas Evans, James Abbruzzese
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 84.
Published: 01 May 2009
View articletitled, Abstract #84: Association of Body Mass Index with Risk, Age of Onset and Survival of Pancreatic Cancer
Journal Articles

Abstract #2783: TGF-\#946;- activated kinase 1 (TAK1) is a drugable target for pancreatic cancer (PC) chemosensitization

Free
Davide Melisi, Qianghua Xia, James Abbruzzese, Paul Chiao
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2783.
Published: 01 May 2009
View articletitled, Abstract #2783: TGF-\#946;- activated kinase 1 (TAK1) is a drugable target for pancreatic cancer (PC) chemosensitization
Journal Articles

Abstract #1168: Characterization of evolving inflammatory status in microenvionment in a transgenic spontaneous PDAC model and correlation with clinical outcomes in human PDAC patients

Free
Ying Ma, Baoan Ji, Huamin Wang, Yan Liu, Defeng Deng, James Abbruzzese, Stephen Ullrich, Yong-Jun Liu, Patrick Hwu, Craig Logsdon, David Chang
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1168.
Published: 01 May 2009
View articletitled, Abstract #1168: Characterization of evolving inflammatory status in microenvionment in a transgenic spontaneous PDAC model and correlation with clinical outcomes in human PDAC patients
Journal Articles

Abstract #2111: Effect of IGF gene polymorphisms alone or in interaction with diabetes on the risk of pancreatic cancer

Free
Suzuki Hideo, Yanan Li, Xiaoqun Dong, Manal Hassan, Ichinosuke Hyodo, James Abbruzzese, Donghui Li
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2111.
Published: 01 May 2009
View articletitled, Abstract #2111: Effect of IGF gene polymorphisms alone or in interaction with diabetes on the risk of pancreatic cancer
Journal Articles

Abstract #2425: Gene expression profiling implicates EMT in global drug resistance in pancreatic cancer

Free
Woonyoung choi, Thiru Arumugam, Keith Fournier, Vijaya Ramachandran, James Abbruzzese, Gary Gallick, Craig Logsdon, David McConkey
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2425.
Published: 01 May 2009
View articletitled, Abstract #2425: Gene expression profiling implicates EMT in global drug resistance in pancreatic cancer
Journal Articles

Old NSAID but new anticancer agent: Tolfenamic acid inhibits pancreatic cancer growth and sensetizes tumor to radiotherapy through downregulation of Sp proteins

Free
Santhi Konduri, Jimmie Colon, Stephen Safe, James Abbruzzese, Cheryl Baker, Maen Abdelrahim
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2312.
Published: 01 May 2008
View articletitled, Old NSAID but new anticancer agent: Tolfenamic acid inhibits pancreatic cancer growth and sensetizes tumor to radiotherapy through downregulation of Sp proteins
Journal Articles

Phase IB study of Src inhibition with dasatinib in combination with 5-fluorouracil, leucovorin, oxaliplatin (FOLFOX) and cetuximab in metastatic colorectal cancer

Free
Scott Kopetz, Robert Wolff, Cathy Eng, Laura Henry, Katrina Glover, David Chang, Michael Overman, Gary Gallick, James Abbruzzese
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-69.
Published: 01 May 2008
View articletitled, Phase IB study of Src inhibition with dasatinib in combination with 5-fluorouracil, leucovorin, oxaliplatin (FOLFOX) and cetuximab in metastatic colorectal cancer
Journal Articles

Phase II study of the novel oral Src-kinase inhibitor, AZD0530, in previously treated advanced colorectal cancer patients

Free
Cathy Eng, Scott Kopetz, Jeffrey Morris, Zulfiqar Malik, David Stewart, Hsiu-yin Chang, Aki Ohinata, James Abbruzzese, Gary Gallick
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-76.
Published: 01 May 2008
View articletitled, Phase II study of the novel oral Src-kinase inhibitor, AZD0530, in previously treated advanced colorectal cancer patients
Journal Articles

Interaction of the SULT1A1 and NAT gene polymorphisms with dietary mutagen intake in modification of the risk of pancreatic cancer

Free
Hideo Suzuki, Yanan Li, Manal Hassan, Melissa Bondy, James Abbruzzese, Donghui Li, Li Jiao, Mark Doll, David Hein, Rena Day
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4737.
Published: 01 May 2008
View articletitled, Interaction of the SULT1A1 and NAT gene polymorphisms with dietary mutagen intake in modification of the risk of pancreatic cancer
Journal Articles

Insulin-like growth factor gene polymorphisms and risk of pancreatic cancer

Free
Donghui Li, Hideo Suzuki, Xiaoqun Dong, Taro Okazaki, Manal Hassan, James Abbruzzese
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4681.
Published: 01 May 2008
View articletitled, Insulin-like growth factor gene polymorphisms and risk of pancreatic cancer