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Journal Articles

Abstract CT198: Immunomodulatory effects of the ATR inhibitor ceralasertib in a window of opportunity biomarker trial in patients with head and neck squamous cell carcinoma

Cancer Res (2023) 83 (8_Supplement): CT198.

https://doi.org/10.1158/1538-7445.AM2023-CT198

Published: 14 April 2023

View article titled, Abstract CT198: Immunomodulatory effects of the ATR inhibitor ceralasertib in a window of opportunity biomarker trial in patients with head and neck squamous cell carcinoma

Journal Articles

Abstract 5466: Functional status of tumor-associated macrophages impacts clinical outcome of durvalumab in patients with advanced NSCLC as revealed by proteomics mass spectrometry

Anna Margaret Hansen, Vivian Ying Wang, Andrew Chambers, David Chain, Jaime Rodriguez Canales, Jorge Blando, Steve Sweet, Zachary A. Cooper, Ashok Gupta, Carl Barrett, Yeoun Jin Kim, Ikbel Achour

Cancer Res (2023) 83 (7_Supplement): 5466.

https://doi.org/10.1158/1538-7445.AM2023-5466

Published: 04 April 2023

View article titled, Abstract 5466: Functional status of tumor-associated macrophages impacts clinical outcome of durvalumab in patients with advanced NSCLC as revealed by proteomics mass spectrometry

Journal Articles

Abstract P3-07-13: The next generation oral selective estrogen receptor degrader (SERD) camizestrant (AZD9833) is active against wild type and mutant estrogen receptor α

Cancer Res (2023) 83 (5_Supplement): P3-07-13.

https://doi.org/10.1158/1538-7445.SABCS22-P3-07-13

Published: 01 March 2023

View article titled, Abstract P3-07-13: The next generation oral selective estrogen receptor degrader (SERD) camizestrant (AZD9833) is active against wild type and mutant estrogen receptor α

Journal Articles

Abstract 1235: Presence of TLS and combined high densities of PD-L1+ macrophages & CD8+ T cells predict long-term overall survival for patients with advanced NSCLC treated with durvalumab

Lina Meinecke, Jorge Blando, Thomas Herz, Michael Surace, Thomas Padel, Monica Azqueta Gavaldon, Harald Hessel, Farzad Sekhavati, Megha Saraiya, Anmarie Boutrin, Karma Da Costa, Jaime Rodriguez Canales, Ashok Gupta, Carl Barrett, Zachary Aaron Cooper, Ikbel Achour

Cancer Res (2022) 82 (12_Supplement): 1235.

https://doi.org/10.1158/1538-7445.AM2022-1235

Published: 15 June 2022

View article titled, Abstract 1235: Presence of TLS and combined high densities of PD-L1+ macrophages & CD8+ T cells predict long-term overall survival for patients with advanced NSCLC treated with durvalumab

Journal Articles

Abstract 399: Tertiary lymphoid structures features associate with outcome in non-small cell lung carcinoma

Cancer Res (2020) 80 (16_Supplement): 399.

https://doi.org/10.1158/1538-7445.AM2020-399

Published: 15 August 2020

View article titled, Abstract 399: Tertiary lymphoid structures features associate with outcome in non-small cell lung carcinoma

Journal Articles

Abstract 4576: Study of the immune contexture in advanced pancreatic neuroendocrine tumors reveals tumor-associated macrophages as promoters of poor survival

Alejandro Francisco-Cruz, Naohiro Uraoka, Suyu Liu, Edwin R. Parra, Luisa M. Solis, Barbara Mino, Arvind Dasari, Jaime Rodriguez-Canales, Michael J. Overman, Jonathan M. Loree, James C. Yao, Ignacio I. Wistuba, Daniel M. Halperin, Jeannelyn S. Estrella

Cancer Res (2019) 79 (13_Supplement): 4576.

https://doi.org/10.1158/1538-7445.AM2019-4576

Published: 01 July 2019

View article titled, Abstract 4576: Study of the immune contexture in advanced pancreatic neuroendocrine tumors reveals tumor-associated macrophages as promoters of poor survival

Journal Articles

Abstract 1180: Impact of the spatial analysis of tumor-associated lymphocytes and tumor-associated macrophages on recurrence at early stage of non-small cell lung carcinoma

Cancer Res (2019) 79 (13_Supplement): 1180.

https://doi.org/10.1158/1538-7445.AM2019-1180

Published: 01 July 2019

View article titled, Abstract 1180: Impact of the spatial analysis of tumor-associated lymphocytes and tumor-associated macrophages on recurrence at early stage of non-small cell lung carcinoma

Journal Articles

Abstract 491: Tumor heterogeneity and its impact on immunoprofiling data: Whole tumor vs regions of interest (ROI) analysis of multiplex immunofluorescence in four carcinoma types

Jaime Rodriguez-Canales, Michael Surace, Jennifer Cann

Cancer Res (2019) 79 (13_Supplement): 491.

https://doi.org/10.1158/1538-7445.AM2019-491

Published: 01 July 2019

View article titled, Abstract 491: Tumor heterogeneity and its impact on immunoprofiling data: Whole tumor vs regions of interest (ROI) analysis of multiplex immunofluorescence in four carcinoma types

Journal Articles

Abstract 3761: Regulation of metastasis by CD8 T lymphocytes

Cancer Res (2019) 79 (13_Supplement): 3761.

https://doi.org/10.1158/1538-7445.AM2019-3761

Published: 01 July 2019

View article titled, Abstract 3761: Regulation of metastasis by CD8 T lymphocytes

Journal Articles

HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress

Brandt A. Nichols, Nathaniel W. Oswald, Elizabeth A. McMillan, Kathleen McGlynn, Jingsheng Yan, Min S. Kim, Janapriya Saha, Prema L. Mallipeddi, Sydnie A. LaDuke, Pamela A. Villalobos, Jaime Rodriguez-Canales, Ignacio I. Wistuba, Bruce A. Posner, Anthony J. Davis, John D. Minna, John B. MacMillan, Angelique W. Whitehurst

Cancer Res (2018) 78 (21): 6196–6208.

https://doi.org/10.1158/0008-5472.CAN-18-1377

Published: 01 November 2018

View article titled, HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress

Includes: Supplementary data

Journal Articles

Abstract 1948: Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers

Masanori Kawakami, Lisa Maria Mustachio, Lin Zheng, Yulong Chen, Jaime Rodriguez-Canales, Barbara Mino, Jonathan M. Kurie, Jason Roszik, Pamela Andrea Villalobos, Kelsie L. Thu, David W. Cescon, Jennifer Silvester, Ignacio Wistuba, Tak W. Mak, Xi Liu, Ethan Dmitrovsky

Cancer Res (2018) 78 (13_Supplement): 1948.

https://doi.org/10.1158/1538-7445.AM2018-1948

Published: 01 July 2018

View article titled, Abstract 1948: Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers

Journal Articles

Abstract 1447: Aberrant tryptophan catabolism marked by high kynureninase expression contributes to immunosuppression and poor outcome in lung adenocarcinoma

Edwin J. Ostrin, Johannes F. Fahrmann, Ichidai Tanaka, Muge Celiktas, Clemente Aguilar, Mitzi Aguilar, Jennifer B. Dennison, Eunice Murage, Satyendra C. Tripathi, Oliver Delgado, Hong Wang, Jaime Rodriguez-Canales, Carmen Behrens, Ignacio I. Wistuba, Ayumu Taguchi, Samir M. Hanash

Cancer Res (2018) 78 (13_Supplement): 1447.

https://doi.org/10.1158/1538-7445.AM2018-1447

Published: 01 July 2018

View article titled, Abstract 1447: Aberrant tryptophan catabolism marked by high kynureninase expression contributes to immunosuppression and poor outcome in lung adenocarcinoma

Journal Articles

Abstract 4686: T cell repertoire evolution from the normal lung to invasive lung adenocarcinoma

Cancer Res (2018) 78 (13_Supplement): 4686.

https://doi.org/10.1158/1538-7445.AM2018-4686

Published: 01 July 2018

View article titled, Abstract 4686: T cell repertoire evolution from the normal lung to invasive lung adenocarcinoma

Journal Articles

Abstract 5377: Tracking genomic and epigenomic evolution from preneoplastic lesions to lung adenocarcinoma by multiregion sequencing

Cancer Res (2018) 78 (13_Supplement): 5377.

https://doi.org/10.1158/1538-7445.AM2018-5377

Published: 01 July 2018

View article titled, Abstract 5377: Tracking genomic and epigenomic evolution from preneoplastic lesions to lung adenocarcinoma by multiregion sequencing

Journal Articles

Abstract 1174: Characterization of the immunologic intra-tumor heterogeneity in early stages of non-small cell lung carcinoma using multiplex immunofluorescence and image analysis approaches

Alejandro Francisco Cruz, Edwin R. Parra, Mei Jiang, Junya Fujimoto, Chi-Wan Chow, Jaime Rodriguez-Canales, Carmen Behrens, Neda Kalhor, Annikka Weissferdt, John Heymach, Stephen Swisher, Boris Sepesi, J. Jack Lee, Cesar Moran, P. Andrew Futreal, Jianjun Zhang, Ignacio I. Wistuba

Cancer Res (2018) 78 (13_Supplement): 1174.

https://doi.org/10.1158/1538-7445.AM2018-1174

Published: 01 July 2018

View article titled, Abstract 1174: Characterization of the immunologic intra-tumor heterogeneity in early stages of non-small cell lung carcinoma using multiplex immunofluorescence and image analysis approaches

Journal Articles

Osteoblast-Secreted Factors Mediate Dormancy of Metastatic Prostate Cancer in the Bone via Activation of the TGFβRIII–p38MAPK–pS249/T252RB Pathway

Li-Yuan Yu-Lee, Guoyu Yu, Yu-Chen Lee, Song-Chang Lin, Jing Pan, Tianhong Pan, Kai-Jie Yu, Bin Liu, Chad J. Creighton, Jaime Rodriguez-Canales, Pamela A. Villalobos, Ignacio I. Wistuba, Eulalia de Nadal, Francesc Posas, Gary E. Gallick, Sue-Hwa Lin

Cancer Res (2018) 78 (11): 2911–2924.

https://doi.org/10.1158/0008-5472.CAN-17-1051

Published: 31 May 2018

View article titled, Osteoblast-Secreted Factors Mediate Dormancy of Metastatic Prostate Cancer in the Bone via Activation of the TGFβRIII–p38MAPK–pS249/T252RB Pathway

Includes: Supplementary data

Journal Articles

Abstract 1111: The chromatin remodelers RUVBL1 and RUVBL2 are prognostic factors and therapeutic targets in non-small cell lung cancer due to their roles in DNA replication, repair, and radiosensitization

Paul Yenerall, Rahul Kollipara, Amit Das, Pamela Villalobos, Long Shan Li, Brenda Timmons, Luc Girard, Jaime Rodriguez-Canales, Ignacio Wistuba, John Minna, Ralf Kittler

Cancer Res (2017) 77 (13_Supplement): 1111.

https://doi.org/10.1158/1538-7445.AM2017-1111

Published: 01 July 2017

View article titled, Abstract 1111: The chromatin remodelers RUVBL1 and RUVBL2 are prognostic factors and therapeutic targets in non-small cell lung cancer due to their roles in DNA replication, repair, and radiosensitization

Journal Articles

Abstract 3328: Protochadherin 7 acts through SET and PP2A to potentiate MAPK signaling by EGFR and KRAS during lung tumorigenesis

Xiaorong Zhou, Barrett L. Updegraff, Yabin Guo, Michael Peyton, Luc Girard, Jill E. Larsen, Xian-Jin Xie, Yunyun Zhou, Tae Hyun Hwang, Yang Xie, Jaime Rodriguez-Canales, Pamela Villalobos, Carmen Behrens, Wistuba I. Ignacio, John D. Minna, Kathryn A. O'Donnell

Cancer Res (2017) 77 (13_Supplement): 3328.

https://doi.org/10.1158/1538-7445.AM2017-3328

Published: 01 July 2017

View article titled, Abstract 3328: Protochadherin 7 acts through SET and PP2A to potentiate MAPK signaling by EGFR and KRAS during lung tumorigenesis

Journal Articles

Abstract 2934: Neoadjuvant chemotherapy influence changes of the immune response in non-small cell lung carcinomas immune response in non-small cell lung carcinomas

Edwin Roger Cuentas, Carmen Behrens, Jaime Rodriguez-Canales, Mei Jiang, Apar Pataer, Arelene Correa, Stephen Swisher, Boris Sepesi, Annikka Weissferdt, Neda Kalhor, Jiexin Zhang, Jack Lee, John Heymach, Cesar Moran, Jianjun Zhang, Don Gibbons, Ignacio Wistuba

Cancer Res (2017) 77 (13_Supplement): 2934.

https://doi.org/10.1158/1538-7445.AM2017-2934

Published: 01 July 2017

View article titled, Abstract 2934: Neoadjuvant chemotherapy influence changes of the immune response in non-small cell lung carcinomas immune response in non-small cell lung carcinomas

Journal Articles

Abstract 861: Olfactomedin 4 downregulation is associated with enhancing epithelial-mesenchymal transition in human benign prostate cells and prostate cancer cells

Hongzhen Li, Wenli Liu, Jianqiong Zhu, Kay Chin, Jaime Rodriguez-Canales, Griffin P. Rodgers

Cancer Res (2017) 77 (13_Supplement): 861.

https://doi.org/10.1158/1538-7445.AM2017-861

Published: 01 July 2017

View article titled, Abstract 861: Olfactomedin 4 downregulation is associated with enhancing epithelial-mesenchymal transition in human benign prostate cells and prostate cancer cells

NARROW

Abstract CT198: Immunomodulatory effects of the ATR inhibitor ceralasertib in a window of opportunity biomarker trial in patients with head and neck squamous cell carcinoma

Abstract 5466: Functional status of tumor-associated macrophages impacts clinical outcome of durvalumab in patients with advanced NSCLC as revealed by proteomics mass spectrometry

Abstract P3-07-13: The next generation oral selective estrogen receptor degrader (SERD) camizestrant (AZD9833) is active against wild type and mutant estrogen receptor α

Abstract 1235: Presence of TLS and combined high densities of PD-L1+ macrophages & CD8+ T cells predict long-term overall survival for patients with advanced NSCLC treated with durvalumab

Abstract 399: Tertiary lymphoid structures features associate with outcome in non-small cell lung carcinoma

Abstract 4576: Study of the immune contexture in advanced pancreatic neuroendocrine tumors reveals tumor-associated macrophages as promoters of poor survival

Abstract 1180: Impact of the spatial analysis of tumor-associated lymphocytes and tumor-associated macrophages on recurrence at early stage of non-small cell lung carcinoma

Abstract 491: Tumor heterogeneity and its impact on immunoprofiling data: Whole tumor vs regions of interest (ROI) analysis of multiplex immunofluorescence in four carcinoma types

Abstract 3761: Regulation of metastasis by CD8 T lymphocytes

HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress

Abstract 1948: Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers

Abstract 1447: Aberrant tryptophan catabolism marked by high kynureninase expression contributes to immunosuppression and poor outcome in lung adenocarcinoma

Abstract 4686: T cell repertoire evolution from the normal lung to invasive lung adenocarcinoma

Abstract 5377: Tracking genomic and epigenomic evolution from preneoplastic lesions to lung adenocarcinoma by multiregion sequencing

Abstract 1174: Characterization of the immunologic intra-tumor heterogeneity in early stages of non-small cell lung carcinoma using multiplex immunofluorescence and image analysis approaches

Osteoblast-Secreted Factors Mediate Dormancy of Metastatic Prostate Cancer in the Bone via Activation of the TGFβRIII–p38MAPK–pS249/T252RB Pathway

Abstract 1111: The chromatin remodelers RUVBL1 and RUVBL2 are prognostic factors and therapeutic targets in non-small cell lung cancer due to their roles in DNA replication, repair, and radiosensitization

Abstract 3328: Protochadherin 7 acts through SET and PP2A to potentiate MAPK signaling by EGFR and KRAS during lung tumorigenesis

Abstract 2934: Neoadjuvant chemotherapy influence changes of the immune response in non-small cell lung carcinomas immune response in non-small cell lung carcinomas

Abstract 861: Olfactomedin 4 downregulation is associated with enhancing epithelial-mesenchymal transition in human benign prostate cells and prostate cancer cells

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