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Jaime F. Modiano
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Journal Articles

Abstract A038 Plasma exosome concentrations in healthy canines and dogs with osteosarcoma

Jaron M. Magstadt, Courtney H. Labé, Meagan Wojtysiak, Kyle DuVal, Ali Khammanivong, Lauren J. Mills, Amber Winter, Caitlin Feiock, Kelly Reid, Mitzi Lewellen, Logan G. Spector, Brenda J. Weigel, Jaime F. Modiano, Kelly M. Makielski
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): A038.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-A038
Published: 05 September 2024
View article titled, Abstract A038 Plasma exosome concentrations in healthy canines and dogs with osteosarcoma
Journal Articles

Abstract LB407: Propranolol may enhance long term survivorship in a subset of dogs with hemangiosarcoma when combined with doxorubicin chemotherapy

Erin B. Dickerson, Jeremy Chacón, Brian D. Husbands, Michael S. Henson, Jaime F. Modiano, Kathleen M. Stuebner, Amber Winter, Sara Pracht, Andrea Chehadeh, Kelly Bergsrud, Caitlin Feiock, Julia Medland, Heather Scavello, Pascale C. Salah, Jennifer Mahoney, Michael O. Childress, David R. Brown, Antonella Borgatti
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB407.
https://doi.org/10.1158/1538-7445.AM2024-LB407
Published: 05 April 2024
View article titled, Abstract LB407: Propranolol may enhance long term survivorship in a subset of dogs with hemangiosarcoma when combined with doxorubicin chemotherapy
Journal Articles

Abstract 7313: Risk assessment, early detection, and strategic prevention of naturally occurring cancers in companion dogs

Jaime F. Modiano, Ashley J. Schulte, Rose Dicovitsky, Taylor A. DePauw, Ali Khammanivong, Mitzi Lewellen, Lauren E. Burt, Daniel A. Vallera, Gary R. Cutter, Amber L. Winter, Kathleen M. Stuebner, Andrea Chehadeh, Sara Pracht, Antonella Borgatti, Michael S. Henson, Erin B. Dickerson, Christopher Ober, Kari L. Anderson, Esther Nell, Aaron L. Sarver
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7313.
https://doi.org/10.1158/1538-7445.AM2024-7313
Published: 22 March 2024
View article titled, Abstract 7313: Risk assessment, early detection, and strategic prevention of naturally occurring cancers in companion dogs
Journal Articles

Abstract A004: Identification and characterization of the cancer permissive environment in companion dogs

Jaime F. Modiano, Ashley J. Schulte, Taylor A. DaPauw, Ali Khammanivong, Jong H. Kim, Aaron L. Sarver, Gary R. Cutter, Eric Lindquist, Kelly M. Makielski
Journal: Cancer Research
Cancer Res (2023) 83 (2_Supplement_1): A004.
https://doi.org/10.1158/1538-7445.AGCA22-A004
Published: 15 January 2023
View article titled, Abstract A004: Identification and characterization of the cancer permissive environment in companion dogs
Journal Articles

Abstract PR008: Identification and characterization of the cancer permissive environment in companion dogs

Jaime F. Modiano, Ashley J. Schulte, Taylor A. DaPauw, Ali Khammanivong, Jong H. Kim, Aaron L. Sarver, Gary R. Cutter, Eric Lindquist, Kelly M. Makielski
Journal: Cancer Research
Cancer Res (2023) 83 (2_Supplement_1): PR008.
https://doi.org/10.1158/1538-7445.AGCA22-PR008
Published: 15 January 2023
View article titled, Abstract PR008: Identification and characterization of the cancer permissive environment in companion dogs
Journal Articles

Abstract 671: Development of an exosomal biomarker signature to detect minimal residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning

Kelly M. Makielski, Alicia J. Donnelly, Ali Khammanivong, Milcah C. Scott, Hirotaka Tomiyasu, John Garbe, Lauren J. Mills, Gary R. Cutter, Andrea Ortiz, Dana C. Galvan, Kristi Ward, Alexa N. Montoya, Brad A. Bryan, Joelle M. Fenger, William C. Kisseberth, Subbaya Subramanian, Jaime F. Modiano
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 671.
https://doi.org/10.1158/1538-7445.AM2021-671
Published: 01 July 2021
View article titled, Abstract 671: Development of an exosomal biomarker signature to detect minimal residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning
Journal Articles

Abstract 1747: Oncolytic Vesicular Stomatitis Virus expressing a species relevant interferon-beta is safe and provides a survival benefit when added as neoadjuvant to the standard of care for dogs with naturally occurring bone cancer

Kelly M. Makielski, Aaron L. Sarver, Aishwarya Sathyanarayan, Michael S. Henson, Kathleen M. Stuebner, Alexandru-Flaviu Tabaran, Ingrid Cornax, Gerard O'Sullivan, Andrea Chehadeh, Donna Groschen, Kelly Bergsrud, Lauren J. Mills, Amber L. Winter, Sara Pracht, Milcah C. Scott, Michael A. Farrar, Gary R. Cutter, Joseph S. Koopmeiners, Stephen J. Russell, Shruthi Naik, Jaime F. Modiano
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1747.
https://doi.org/10.1158/1538-7445.AM2021-1747
Published: 01 July 2021
View article titled, Abstract 1747: Oncolytic Vesicular Stomatitis Virus expressing a species relevant interferon-beta is safe and provides a survival benefit when added as neoadjuvant to the standard of care for dogs with naturally occurring bone cancer
Journal Articles

Abstract PO007: Role of PI3K pathway in reprogramming the tumor niche of angiosarcoma

Sophia Wenthe, Ashley J. Schulte, Mathew G. Angelos, Dan S. Kaufman, Jaime F. Modiano, Jong Hyuk Kim
Journal: Cancer Research
Cancer Res (2021) 81 (5_Supplement): PO007.
https://doi.org/10.1158/1538-7445.TME21-PO007
Published: 01 March 2021
View article titled, Abstract PO007: Role of PI3K pathway in reprogramming the tumor niche of angiosarcoma
Journal Articles

Abstract 195: Molecular mechanisms that activate convergent oncogenic pathway in genomically complex angiosarcoma

Jong Hyuk Kim, Kate Megquier, Aaron L. Sarver, Rachael Thomas, Ashley J. Schulte, Chao Wang, Ingegerd Elvers, Elinor Karlsson, Matthew Breen, Kerstin Lindblad-Toh, Jaime F. Modiano
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 195.
https://doi.org/10.1158/1538-7445.AM2020-195
Published: 15 August 2020
View article titled, Abstract 195: Molecular mechanisms that activate convergent oncogenic pathway in genomically complex angiosarcoma
Journal Articles

Abstract 4592: Early detection for strategic prevention of a terminal canine cancer: A model to reduce the impact of cancer in our society

Jaime F. Modiano, Taylor A. DePauw, Ali Khammanivong, Ashley J. Schulte, Amber L. Winter, Jong Kim, Kathleen Stuebner, Andrea Fahrenkrug, Daniel A. Vallera, Antonella Borgatti, Erin B. Dickerson, Michael S. Henson
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4592.
https://doi.org/10.1158/1538-7445.AM2020-4592
Published: 15 August 2020
View article titled, Abstract 4592: Early detection for strategic prevention of a terminal canine cancer: A model to reduce the impact of cancer in our society
Journal Articles

Abstract 1341: Magnetic isolation and identification of exosomes using Fe/Au nanowires

Zohreh Nemati, Thomas Gage, Mohammad Reza Zamani Kouhpanji, Joseph Um, Alicia Donnelly, Daniel Shore, Kelly Makielski, Yali Zhang, Rhonda Franklin, Jaime F. Modiano, Bethanie J. Stadler
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1341.
https://doi.org/10.1158/1538-7445.AM2019-1341
Published: 01 July 2019
View article titled, Abstract 1341: Magnetic isolation and identification of exosomes using Fe/Au nanowires
Journal Articles

Abstract 3715: Cancer as a consequence of breaking through evolutionary constraints on longevity

Jaime F. Modiano, Aaron L. Sarver
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3715.
https://doi.org/10.1158/1538-7445.AM2019-3715
Published: 01 July 2019
View article titled, Abstract 3715: Cancer as a consequence of breaking through evolutionary constraints on longevity
Journal Articles

Abstract 2264: RNA sequencing based analysis of transposon-induced tumors reveals novel insights into cancer pathogenesis and progression

Emily T. Camilleri, Pauli J. Beckmann, Jon D. Larson, Morito Kurata, Jingmin Shu, Emily Pope, Wendy A. Hudson, Nuri A. Temiz, Susan K. Rathe, Rebecca S. LaRue, Anne E. Sarver, Milcah C. Scott, Jyotika Varshney, Jaime F. Modiano, Branden S. Moriarity, Aaron L. Sarver, Somasekar Seshagiri, David A. Largaespada
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2264.
https://doi.org/10.1158/1538-7445.AM2018-2264
Published: 01 July 2018
View article titled, Abstract 2264: RNA sequencing based analysis of transposon-induced tumors reveals novel insights into cancer pathogenesis and progression
Journal Articles

Abstract 824: Targeting epidermal growth factor receptors and urokinase-type plasminogen activator receptors for sarcoma therapy

Ashley J. Graef, Jong-Hyuk Kim, Daniel A. Vallera, Jaime F. Modiano
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 824.
https://doi.org/10.1158/1538-7445.AM2018-824
Published: 01 July 2018
View article titled, Abstract 824: Targeting epidermal growth factor receptors and urokinase-type plasminogen activator receptors for sarcoma therapy
Journal Articles

SETD2 Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma

Sharadha Sakthikumar, Ingegerd Elvers, Jaegil Kim, Maja L. Arendt, Rachael Thomas, Jason Turner-Maier, Ross Swofford, Jeremy Johnson, Steven E. Schumacher, Jessica Alföldi, Erik Axelsson, C. Guillermo Couto, William C. Kisseberth, Mats E. Pettersson, Gad Getz, Jennifer R.S. Meadows, Jaime F. Modiano, Matthew Breen, Marcin Kierczak, Karin Forsberg-Nilsson, Voichita D. Marinescu, Kerstin Lindblad-Toh
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (13): 3421–3431.
https://doi.org/10.1158/0008-5472.CAN-17-3558
Published: 01 July 2018
View article titled, <em>SETD2</em> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma
Open the PDF for <em>SETD2</em> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma in another window
Includes: Supplementary data
Journal Articles

Abstract 5357: Mutational and transcriptomic profiling identify distinct angiogenic and inflammatory subtypes of angiosarcoma

Jong Hyuk Kim, Kate Megquier, Aaron L. Sarver, Rachael Thomas, Chao Wang, Ingegerd Elvers, Elinor Karlsson, Matthew Breen, Kerstin Lindblad-Toh, Jaime F. Modiano
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5357.
https://doi.org/10.1158/1538-7445.AM2018-5357
Published: 01 July 2018
View article titled, Abstract 5357: Mutational and transcriptomic profiling identify distinct angiogenic and inflammatory subtypes of angiosarcoma
Journal Articles

Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma

Milcah C. Scott, Nuri A. Temiz, Anne E. Sarver, Rebecca S. LaRue, Susan K. Rathe, Jyotika Varshney, Natalie K. Wolf, Branden S. Moriarity, Timothy D. O'Brien, Logan G. Spector, David A. Largaespada, Jaime F. Modiano, Subbaya Subramanian, Aaron L. Sarver
Journal: Cancer Research
Cancer Res (2018) 78 (2): 326–337.
https://doi.org/10.1158/0008-5472.CAN-17-0576
Published: 15 January 2018
View article titled, Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma
Open the PDF for Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma in another window
Includes: Supplementary data
Journal Articles

Abstract 817: Unbiased discovery of exosome-associated biomarkers using xenograft models

Milcah C. Scott, John R. Garbe, Hirotaka Tomiyasu, Alicia Donnelly, Brad A. Bryan, Subbaya Subramanian, Jaime F. Modiano
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 817.
https://doi.org/10.1158/1538-7445.AM2017-817
Published: 01 July 2017
View article titled, Abstract 817: Unbiased discovery of exosome-associated biomarkers using xenograft models
Journal Articles

Abstract 1694: Preclinical evaluation of a novel bispecific targeted toxin for the treatment of sarcomas

Antonella Borgatti, Amber Winter, Kathleen Stuebner, Joseph Koopmeiners, Jaime F. Modiano, Daniel Vallera
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1694.
https://doi.org/10.1158/1538-7445.AM2015-1694
Published: 01 August 2015
View article titled, Abstract 1694: Preclinical evaluation of a novel bispecific targeted toxin for the treatment of sarcomas
Journal Articles

Abstract 4082: CD47 blockade to enhance adaptive anti-tumor immune responses

Katie L. Anderson, Daisuke Ito, Debra C. Lins, Julie M. Curtsinger, Matthew F. Mescher, Jaime F. Modiano
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4082.
https://doi.org/10.1158/1538-7445.AM2014-4082
Published: 01 October 2014
View article titled, Abstract 4082: CD47 blockade to enhance adaptive anti-tumor immune responses