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Jack Pollard
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Journal Articles

Abstract 3367: Tumor-derived Extracellular Vesicles as a potential PD biomarker for TEAD central pocket binder activity in liquid biopsy

Free
Manoel Nunes, Emmanuel Spanakis, Wilson Dos-Santos-Bele, Emilia Rabia, Stephane Soubigou, Gaelle Muzard, Odette Dos-Santos, Jack Pollard, Angela Hadjipanayis, Fabien Delahaye, Olivier Venier, Laurent Debussche, Don Jackson, Colette Dib, Iris Valtingojer, Matteo Cesaroni
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3367.
https://doi.org/10.1158/1538-7445.AM2023-3367
Published: 04 April 2023
View articletitled, Abstract 3367: Tumor-derived Extracellular Vesicles as a potential PD biomarker for TEAD central pocket binder activity in liquid biopsy
Journal Articles

Meta-Analysis of Human Cancer Single-Cell RNA-Seq Datasets Using the IMMUcan Database

Open Access
Jordi Camps, Floriane Noël, Robin Liechti, Lucile Massenet-Regad, Sidwell Rigade, Lou Götz, Caroline Hoffmann, Elise Amblard, Melissa Saichi, Mahmoud M. Ibrahim, Jack Pollard, Jasna Medvedovic, Helge G. Roider, Vassili Soumelis
Journal: Cancer Research
Cancer Res (2023) 83 (3): 363–373.
https://doi.org/10.1158/0008-5472.CAN-22-0074
Published: 03 February 2023
View articletitled, Meta-Analysis of Human Cancer Single-Cell RNA-Seq Datasets Using the IMMUcan Database
Open the PDF for Meta-Analysis of Human Cancer Single-Cell RNA-Seq Datasets Using the IMMUcan Database in another window
Includes: Supplementary data
Journal Articles

Abstract 5590: Inhibition of the autophagy protein Vps34 induces tumor cell secretion of proinflammatory chemokines

Free
Marie Bernardo, Yu-an Zhang, Martin Graf, Jane Cheng, Fangxian Sun, Virna Cortez-Retamozo, Sukhvinder Sidhu, Eladio Marquez, Donald Jackson, Jack Pollard, Timothy R. Wagenaar, Donald Shaffer
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5590.
https://doi.org/10.1158/1538-7445.AM2022-5590
Published: 15 June 2022
View articletitled, Abstract 5590: Inhibition of the autophagy protein Vps34 induces tumor cell secretion of proinflammatory chemokines
Journal Articles

Abstract 5011: Meta-analysis of human cancer single cell RNAseq datasets using the fully integrated IMMUcan database

Free
Jordi Camps, Floriane Noel, Robin Liechti, Lou Goetz, Caroline Hoffmann, Lucile Massenet-Regad, Elise Amblard, Melissa Saichi, Mahmoud M. Ibrahim, Jack Pollard, Jasna Medvedovic, Helge G. Roider, Vassili Soumelis
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5011.
https://doi.org/10.1158/1538-7445.AM2022-5011
Published: 15 June 2022
View articletitled, Abstract 5011: Meta-analysis of human cancer single cell RNAseq datasets using the fully integrated IMMUcan database
Journal Articles

Abstract 762: Practical guidelines for the design of single cell sequencing studies

Free
Amir Bayegan, Julien Tessier, Emma Wang, Adalis Maisonet, Shu Yan, Shannon McGrath, Donald G. Jackson, Jack Pollard
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 762.
https://doi.org/10.1158/1538-7445.AM2022-762
Published: 15 June 2022
View articletitled, Abstract 762: Practical guidelines for the design of single cell sequencing studies
Journal Articles

Abstract P4-02-08: Amcenestrant in combination with CDK4/6 inhibitor palbociclib demonstrates synergistic anti-tumor activity in ER+ endocrine-resistant breast cancer xenograft models

Free
Maysoun Shomali, Zhuyan Guo, Jane Cheng, Amy Sullivan, Youssef El-Ahmad, Fangxian Sun, Sukhvinder Sidhu, Joon Sang Lee, Hui Cai, Jack Pollard, Laurent Debussche, Chris Soria, Monsif Bouaboula
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P4-02-08.
https://doi.org/10.1158/1538-7445.SABCS21-P4-02-08
Published: 15 February 2022
View articletitled, Abstract P4-02-08: Amcenestrant in combination with CDK4/6 inhibitor palbociclib demonstrates synergistic anti-tumor activity in ER+ endocrine-resistant breast cancer xenograft models
Journal Articles

Abstract 1590: An experimental tumor model resistant to anti-PD-1 is sensitive to local mRNA immunotherapy

Free
Marie Bernardo, Tatiana Tolstykh, Yu-an Zhang, Dinesh S. Bangari, Hui Cao, Kerstin A. Heyl, Joon Sang Lee, Natalia Malkova, Jack Pollard, Hui Qu, Fangxian Sun, Dmitri Wiederschain, Timothy R. Wagenaar
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1590.
https://doi.org/10.1158/1538-7445.AM2021-1590
Published: 01 July 2021
View articletitled, Abstract 1590: An experimental tumor model resistant to anti-PD-1 is sensitive to local mRNA immunotherapy
Journal Articles

Abstract 1909: Pan-TGF-β inhibition with PD-1 blockade as a combination treatment strategy to augment anti-tumor immune response in hepatocellular carcinoma

Free
Natalia Malkova, Joachim Theilhaber, Mikhail Levit, Tatiana Tolstykh, Andrew Hebert, Kevin Atchison, Adalis Maisonet, Sara Sara Sinicropi-Yao, Alexei Protopopov, Jack Pollard, Sukhvinder Sidhu, Tun Tun Lin, Lily Pao, Dmitri Wiederschain, Sharad K. Sharma
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1909.
https://doi.org/10.1158/1538-7445.AM2021-1909
Published: 01 July 2021
View articletitled, Abstract 1909: Pan-TGF-β inhibition with PD-1 blockade as a combination treatment strategy to augment anti-tumor immune response in hepatocellular carcinoma
Journal Articles

Abstract 2161: A transcriptomic signature for measuring YAP1 activity in patient samples and tumor models

Free
Emmanuel Spanakis, Loreley Calvet, Odette Dos Santos, Colette Dib, Sukhvinder Sidhu, Jurgen Moll, Laurent Debussche, Jack Pollard, Iris Valtingojer
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2161.
https://doi.org/10.1158/1538-7445.AM2021-2161
Published: 01 July 2021
View articletitled, Abstract 2161: A transcriptomic signature for measuring YAP1 activity in patient samples and tumor models
Journal Articles

Abstract 2280: A comprehensive sample tracking and data processing workflow for next generation sequencing

Free
Chandra Sekhar Pedamallu, Joon Sang Lee, Shu Yan, Adalis Maisonet, Aleksandr Sidoruk, Tengui Chen, Yulia Kamyshova, Mariia Zueva, Mark Magid, Quan Wan, Jeffrey Thompson, Valerie Zebrouck, Immanuel Gadaczek, Mikhail Alperovich, Brian McNatt, Alexei Protopopov, Donald Jackson, Jack Pollard
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2280.
https://doi.org/10.1158/1538-7445.AM2021-2280
Published: 01 July 2021
View articletitled, Abstract 2280: A comprehensive sample tracking and data processing workflow for next generation sequencing
Journal Articles

Abstract 739: Preclinical and clinical activity of SAR439859, Amcenestrant, a next generation SERD

Free
Maysoun Shomali, Fangxian Sun, Laurent Besret, Anne Caron, Joon Sang Lee, Youssef El-Ahmed, Laurent Schio, Jack Pollard, Vasiliki Pelekanou, Patrick Cohen, Marina Celanovic, Christina Herold, Chris Soria, Laurent Debussche, Monsif Bouaboula
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 739.
https://doi.org/10.1158/1538-7445.AM2021-739
Published: 01 July 2021
View articletitled, Abstract 739: Preclinical and clinical activity of SAR439859, Amcenestrant, a next generation SERD
Journal Articles

Abstract 406: Development of a gene signature assessing ER modulation by SERMs and SERDs as a target engagement biomarker for endocrine therapy in breast cancer

Free
Joon Sang Lee, Maysoun Shomali, Monsif Bouaboula, Emma Wang, Wilson Dos-Santos-Bele, Colette Dib, Eric Boitier, Vasiliki Pelekanou, Nils Ternes, Alice Gosselin, Patrick Cohen, Marina Celanovic, Christopher Soria, Alexei Protopopov, Jack Pollard
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 406.
https://doi.org/10.1158/1538-7445.AM2021-406
Published: 01 July 2021
View articletitled, Abstract 406: Development of a gene signature assessing ER modulation by SERMs and SERDs as a target engagement biomarker for endocrine therapy in breast cancer
Journal Articles

Abstract 2279: Improving cell type and state classification in CITE-seq using probabilistic models and hierarchical cell ID matrix

Free
Lila Fakharzadeh, Julien Tessier, Shannon McGrath, Emma Wang, Angelique Biancotto, Alexei Protopopov, Jack Pollard, Joon Sang Lee
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2279.
https://doi.org/10.1158/1538-7445.AM2021-2279
Published: 01 July 2021
View articletitled, Abstract 2279: Improving cell type and state classification in CITE-seq using probabilistic models and hierarchical cell ID matrix
Journal Articles

Abstract PS17-16: Sar439859, a novel selective estrogen receptor degrader (serd), demonstrates effective and broad antitumor activity in wild-type and mutant er-positive breast cancer models

Free
Maysoun Shomali, Fangxian Sun, Mikhail Levit, Jack Pollard, Joon Sang Lee, Laurent Schio, Youssef El-Ahmad, Chris Soria, Patrick Cohen, Laurent Debussche, Monsif Bouaboula
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS17-16.
https://doi.org/10.1158/1538-7445.SABCS20-PS17-16
Published: 15 February 2021
View articletitled, Abstract PS17-16: Sar439859, a novel selective estrogen receptor degrader (serd), demonstrates effective and broad antitumor activity in wild-type and mutant er-positive breast cancer models
Journal Articles

Abstract 4858: Oncogenic HIPPO-YAP1: in vivo target validation of YAP1 in malignant mesothelioma

Free
Loreley Calvet, Odette Dos Santos, Véronique Jean-Baptiste, Emmanuel Spanakis, Yvette Ruffin, Isabelle Sanchez, Jessica Mestadier, Stéphane Soubigou, Sylvie Feteanu, Pascale Picard, Chagri Boumaya, Jack Pollard, Colette Dib, Sukhvinder Sidhu, Laurent Debussche, Iris Valtingojer
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4858.
https://doi.org/10.1158/1538-7445.AM2020-4858
Published: 15 August 2020
View articletitled, Abstract 4858: Oncogenic HIPPO-YAP1: in vivo target validation of YAP1 in malignant mesothelioma
Journal Articles

Abstract 832: Construction and optimization of gene expression signatures for prediction of survival in two-arm clinical trials

Free
Joachim Theilhaber, Marielle Chiron, Jennifer Dreymann, Donald Bergstrom, Jack Pollard
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 832.
https://doi.org/10.1158/1538-7445.AM2020-832
Published: 15 August 2020
View articletitled, Abstract 832: Construction and optimization of gene expression signatures for prediction of survival in two-arm clinical trials
Journal Articles

Abstract 773: Tumor-derived Extracellular Vesicles (EVs) expressing TGFb as potential biomarkers for anti-TGFb antibody activity and drug activity in liquid biopsy

Free
Manoel Nunes, Camille Bernard, Gaelle Muzard, Wilson Dos-Santos-Bele, Jack Pollard, Alexei Protopopov, Colette Dib
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 773.
https://doi.org/10.1158/1538-7445.AM2020-773
Published: 15 August 2020
View articletitled, Abstract 773: Tumor-derived Extracellular Vesicles (EVs) expressing TGFb as potential biomarkers for anti-TGFb antibody activity and drug activity in liquid biopsy
Journal Articles

Abstract 4451: Combination of local mRNA immunotherapy with systemic immune checkpoint blockade demonstrates anti-tumor activity across a diverse range of preclinical syngeneic tumor models

Free
Natalia V. Malkova, Tatiana Tolstykh, Mikhail Levit, Joachim Theilhaber, Andrew Hebert, Kevin Atchison, Adalis Maisonet, Christian Hotz, Ugur Sahin, Alexei Protopopov, Jack Pollard, Sukhvinder Sidhu, Dmitri Wiederschain, Timothy R. Wagenaar
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4451.
https://doi.org/10.1158/1538-7445.AM2020-4451
Published: 15 August 2020
View articletitled, Abstract 4451: Combination of local mRNA immunotherapy with systemic immune checkpoint blockade demonstrates anti-tumor activity across a diverse range of preclinical syngeneic tumor models
Journal Articles

Abstract 4321: Integrating multiplex immunohistochemistry (IHC) and transcriptomics for characterization of association between spatial heterogeneity of lymphocytic infiltration and TGFβ pathway activity in solid tumors

Free
Joachim Theilhaber, Jack Pollard, Robert Pomponio, Michele Sanicola-Nadel, Anne Caron, Souâd Naimi, Dmitri Wiederschain, Tun Tun Lin, Rui Wang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4321.
https://doi.org/10.1158/1538-7445.AM2020-4321
Published: 15 August 2020
View articletitled, Abstract 4321: Integrating multiplex immunohistochemistry (IHC) and transcriptomics for characterization of association between spatial heterogeneity of lymphocytic infiltration and TGFβ pathway activity in solid tumors
Journal Articles

Abstract 174: Genomic cytometry characterization of preclinical models for development of immune-oncology therapeutics

Free
Joon Sang Lee, Shannon McGrath, Emma Wang, Maximilian Rogers-Grazado, Yu-an Zhang, Natalia Malkova, Jack Pollard, Alexei Protopopov
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 174.
https://doi.org/10.1158/1538-7445.AM2020-174
Published: 15 August 2020
View articletitled, Abstract 174: Genomic cytometry characterization of preclinical models for development of immune-oncology therapeutics