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Jacek Zielonka
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Journal Articles

Abstract 3589: Targeting metabolic reprogramming and OXPHOS as a viable anti-melanoma strategy

Free
Gang Cheng, Jacek Zielonka, Micael Hardy, Michael B. Dwinell, Balaraman Kalyanaraman
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3589.
https://doi.org/10.1158/1538-7445.AM2019-3589
Published: 01 July 2019
View articletitled, Abstract 3589: Targeting metabolic reprogramming and OXPHOS as a viable anti-melanoma strategy
Journal Articles

Abstract 878: Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation

Free
Kathleen A. Boyle, Jonathan VanWickle, Jacek Zielonka, Gang Cheng, Balaraman Kalyanaraman, Michael B. Dwinell
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 878.
https://doi.org/10.1158/1538-7445.AM2018-878
Published: 01 July 2018
View articletitled, Abstract 878: Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation
Journal Articles

Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells

Free
Gang Cheng, Jacek Zielonka, Olivier Ouari, Marcos Lopez, Donna McAllister, Kathleen Boyle, Christy S. Barrios, James J. Weber, Bryon D. Johnson, Micael Hardy, Michael B. Dwinell, Balaraman Kalyanaraman
Journal: Cancer Research
Cancer Res (2016) 76 (13): 3904–3915.
https://doi.org/10.1158/0008-5472.CAN-15-2534
Published: 30 June 2016
View articletitled, Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells
Open the PDF for Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 498: Blunting the radical scavenging property of mitochondria-targeted, triphenylphosphonium-linked antioxidants failed to mitigate their anti-proliferative and antitumor effects

Free
Gang Cheng, Jacek Zielonka, Joy Joseph, Balaraman Kalyanaraman
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 498.
https://doi.org/10.1158/1538-7445.AM2014-498
Published: 01 October 2014
View articletitled, Abstract 498: Blunting the radical scavenging property of mitochondria-targeted, triphenylphosphonium-linked antioxidants failed to mitigate their anti-proliferative and antitumor effects
Journal Articles

Abstract 1705: Bioenergetic changes in glycolysis, Kreb's cycle, and glutaminolysis in pancreatic cells treated with mitochondria-targeted cationic drugs.

Free
Gang Cheng, Jacek Zielonka, Joy Joseph, Balaraman Kalyanaraman
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1705.
https://doi.org/10.1158/1538-7445.AM2013-1705
Published: 15 April 2013
View articletitled, Abstract 1705: Bioenergetic changes in glycolysis, Kreb's cycle, and glutaminolysis in pancreatic cells treated with mitochondria-targeted cationic drugs.
Journal Articles

Mitochondria-Targeted Drugs Synergize with 2-Deoxyglucose to Trigger Breast Cancer Cell Death

Free
Gang Cheng, Jacek Zielonka, Brian P. Dranka, Donna McAllister, A. Craig Mackinnon, Jr, Joy Joseph, Balaraman Kalyanaraman
Journal: Cancer Research
Cancer Res (2012) 72 (10): 2634–2644.
https://doi.org/10.1158/0008-5472.CAN-11-3928
Published: 14 May 2012
View articletitled, Mitochondria-Targeted Drugs Synergize with 2-Deoxyglucose to Trigger Breast Cancer Cell Death
Open the PDF for Mitochondria-Targeted Drugs Synergize with 2-Deoxyglucose to Trigger Breast Cancer Cell Death in another window
Includes: Supplementary data
Journal Articles

Abstract 1136: Synergistic inhibition of bioenergetic pathways in pancreatic cancer cells by mitochondria-targeted nitroxide and glycolytic inhibitors

Free
Gang Cheng, Jacek Zielonka, Joy Joseph, Balaraman Kalyanaraman
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1136.
https://doi.org/10.1158/1538-7445.AM2012-1136
Published: 15 April 2012
View articletitled, Abstract 1136: Synergistic inhibition of bioenergetic pathways in pancreatic cancer cells by mitochondria-targeted nitroxide and glycolytic inhibitors
Journal Articles

Abstract 4452: Induction of cell and autophagy by the anticancer redox agent mitoquinone is regulated by Nrf2

Free
V. Ashutosh Rao, Sarah Klein, Naoko Mizuno, Jacek Zielonka, Balarama Kalyanaraman, Emily Shacter
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4452.
https://doi.org/10.1158/1538-7445.AM10-4452
Published: 15 April 2010
View articletitled, Abstract 4452: Induction of cell and autophagy by the anticancer redox agent mitoquinone is regulated by Nrf2
Journal Articles

Cyclooxygenase 2 Rescues LNCaP Prostate Cancer Cells from Sanguinarine-Induced Apoptosis by a Mechanism Involving Inhibition of Nitric Oxide Synthase Activity

Free
Jacob Huh, Andrejs Liepins, Jacek Zielonka, Christopher Andrekopoulos, Balaraman Kalyanaraman, Andrey Sorokin
Journal: Cancer Research
Cancer Res (2006) 66 (7): 3726–3736.
https://doi.org/10.1158/0008-5472.CAN-05-4033
Published: 03 April 2006
View articletitled, Cyclooxygenase 2 Rescues LNCaP Prostate Cancer Cells from Sanguinarine-Induced Apoptosis by a Mechanism Involving Inhibition of Nitric Oxide Synthase Activity
Open the PDF for Cyclooxygenase 2 Rescues LNCaP Prostate Cancer Cells from Sanguinarine-Induced Apoptosis by a Mechanism Involving Inhibition of Nitric Oxide Synthase Activity in another window
Includes: Supplementary data