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Journal Articles

Cell Death Identification in Anticancer Therapy—Letter

J. Martin Brown, Bradly G. Wouters, David G. Kirsch

Cancer Res (2015) 75 (17): 3681.

https://doi.org/10.1158/0008-5472.CAN-15-0908

Published: 31 August 2015

View article titled, Cell Death Identification in Anticancer Therapy—Letter

Journal Articles

Abstract 3348: Tumor irradiation induced a phenotype change of monocytes to facilitate vascular regrowth

Lei Deng, Jason Stafford, Sophia Chernikova, Shie-chau Liu, Jianguo Sun, J. Martin Brown

Cancer Res (2015) 75 (15_Supplement): 3348.

https://doi.org/10.1158/1538-7445.AM2015-3348

Published: 01 August 2015

View article titled, Abstract 3348: Tumor irradiation induced a phenotype change of monocytes to facilitate vascular regrowth

Journal Articles

Abstract B71: Inhibiting the CSF-1 receptor on tumor-infiltrating monocytes may enhance the efficacy of radiotherapy for glioblastoma multiforme

Jason H. Stafford, Sophia Chernikova, Brian L. West, J. Martin Brown

Cancer Res (2015) 75 (1_Supplement): B71.

https://doi.org/10.1158/1538-7445.CHTME14-B71

Published: 12 January 2015

View article titled, Abstract B71: Inhibiting the CSF-1 receptor on tumor-infiltrating monocytes may enhance the efficacy of radiotherapy for glioblastoma multiforme

Journal Articles

Abstract A13: Hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis by regulating VEGF and S100A8 production

G-One Ahn, Young-Eun Kim, Beom-Ju Hong, Seoyeon Bok, Chan-Ju Lee, Hak Jae Kim, Il Han Kim, Jun Seita, Irving Weissman, J Martin Brown

Cancer Res (2015) 75 (1_Supplement): A13.

https://doi.org/10.1158/1538-7445.CHTME14-A13

Published: 12 January 2015

View article titled, Abstract A13: Hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis by regulating VEGF and S100A8 production

Journal Articles

Abstract 386: Inhibiting the CSF-1 receptor on tumor-infiltrating monocytes may enhance the efficacy of radiotherapy for glioblastoma multiforme.

Jason H. Stafford, Sophia Chernikova, Brian West, J. Martin Brown

Cancer Res (2013) 73 (8_Supplement): 386.

https://doi.org/10.1158/1538-7445.AM2013-386

Published: 15 April 2013

View article titled, Abstract 386: Inhibiting the CSF-1 receptor on tumor-infiltrating monocytes may enhance the efficacy of radiotherapy for glioblastoma multiforme.

Journal Articles

Abstract 385: Inhibition of recurrences of experimental brain tumors after irradiation by blocking the activity of SDF-1 (CXCL12) using the Spiegelmer® NOX-A12.

Shie-Chau Liu, Reem Alomran, Jason Stafford, Milton Merchant, Taichang Jang, Stefan Zollner, Anna Kruschinski, Laurence Recht, J. Martin Brown

Cancer Res (2013) 73 (8_Supplement): 385.

https://doi.org/10.1158/1538-7445.AM2013-385

Published: 15 April 2013

View article titled, Abstract 385: Inhibition of recurrences of experimental brain tumors after irradiation by blocking the activity of SDF-1 (CXCL12) using the Spiegelmer® NOX-A12.

Journal Articles

Abstract 383: Investigation of endothelial progenitor cells as mediators of radiation resistance.

Jeffery S. Russell, J. Martin Brown

Cancer Res (2013) 73 (8_Supplement): 383.

https://doi.org/10.1158/1538-7445.AM2013-383

Published: 15 April 2013

View article titled, Abstract 383: Investigation of endothelial progenitor cells as mediators of radiation resistance.

Journal Articles

Deficiency in Mammalian Histone H2B Ubiquitin Ligase Bre1 (Rnf20/Rnf40) Leads to Replication Stress and Chromosomal Instability

Sophia B. Chernikova, Olga V. Razorenova, John P. Higgins, Brock J. Sishc, Monica Nicolau, Jennifer A. Dorth, Diana A. Chernikova, Shirley Kwok, James D. Brooks, Susan M. Bailey, John C. Game, J. Martin Brown

Cancer Res (2012) 72 (8): 2111–2119.

https://doi.org/10.1158/0008-5472.CAN-11-2209

Published: 16 April 2012

View article titled, Deficiency in Mammalian Histone H2B Ubiquitin Ligase Bre1 (Rnf20/Rnf40) Leads to Replication Stress and Chromosomal Instability

Includes: Supplementary data

Journal Articles

Overcoming Hypoxia-Induced Apoptotic Resistance through Combinatorial Inhibition of GSK-3β and CDK1

Patrick A. Mayes, Nathan G. Dolloff, Colin J. Daniel, J. Judy Liu, Lori S. Hart, Kageaki Kuribayashi, Joshua E. Allen, David I.H. Jee, Jay F. Dorsey, Yingqiu Y. Liu, David T. Dicker, J. Martin Brown, Emma E. Furth, Peter S. Klein, Rosalie C. Sears, Wafik S. El-Deiry

Cancer Res (2011) 71 (15): 5265–5275.

https://doi.org/10.1158/0008-5472.CAN-11-1383

Published: 28 July 2011

View article titled, Overcoming Hypoxia-Induced Apoptotic Resistance through Combinatorial Inhibition of GSK-3β and CDK1

Includes: Supplementary data

Journal Articles

Abstract #1294: Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A

Gu Yongchuan, Adam Patterson, Graham Atwell, Sophia Chernikova, J. Martin Brown, Larry Thompson, William Wilson

Cancer Res (2009) 69 (9_Supplement): 1294.

Published: 01 May 2009

View article titled, Abstract #1294: Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A

Journal Articles

DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity

Rachelle S. Singleton, Christopher P. Guise, Dianne M. Ferry, Susan M. Pullen, Mary J. Dorie, J. Martin Brown, Adam V. Patterson, William R. Wilson

Cancer Res (2009) 69 (9): 3884–3891.

https://doi.org/10.1158/0008-5472.CAN-08-4023

Published: 30 April 2009

View article titled, DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity

Includes: Supplementary data

Journal Articles

Optimized Clostridium-Directed Enzyme Prodrug Therapy Improves the Antitumor Activity of the Novel DNA Cross-Linking Agent PR-104

Shie-Chau Liu, G-One Ahn, Mitomu Kioi, Mary-Jo Dorie, Adam V. Patterson, J. Martin Brown

Cancer Res (2008) 68 (19): 7995–8003.

https://doi.org/10.1158/0008-5472.CAN-08-1698

Published: 30 September 2008

View article titled, Optimized <em>Clostridium</em>-Directed Enzyme Prodrug Therapy Improves the Antitumor Activity of the Novel DNA Cross-Linking Agent PR-104

Includes: Supplementary data

Journal Articles

Role of MMP-9 expressing bone marrow-derived myelomonocytic cells in tumor vasculogenesis.

G-One Ahn, J. Martin Brown

Cancer Res (2008) 68 (9_Supplement): 1133.

Published: 01 May 2008

View article titled, Role of MMP-9 expressing bone marrow-derived myelomonocytic cells in tumor vasculogenesis.

Journal Articles

Homologous Recombination Is the Principal Pathway for the Repair of DNA Damage Induced by Tirapazamine in Mammalian Cells

James W. Evans, Sophia B. Chernikova, Lisa A. Kachnic, Judit P. Banath, Olivier Sordet, Yvette M. Delahoussaye, Alejandro Treszezamsky, Brian H. Chon, Zhihui Feng, Yongchuan Gu, William R. Wilson, Yves Pommier, Peggy L. Olive, Simon N. Powell, J. Martin Brown

Cancer Res (2008) 68 (1): 257–265.

https://doi.org/10.1158/0008-5472.CAN-06-4497

Published: 02 January 2008

View article titled, Homologous Recombination Is the Principal Pathway for the Repair of DNA Damage Induced by Tirapazamine in Mammalian Cells

Journal Articles

Yeast Bre1 and Dot1 histone modification enzymes are necessary for efficient homologous recombination repair

Kelly McCann, Tatiana Spicakova, Marsha Williamson, John Game, J. Martin Brown

Cancer Res (2007) 67 (9_Supplement): LB-234.

Published: 01 May 2007

View article titled, Yeast Bre1 and Dot1 histone modification enzymes are necessary for efficient homologous recombination repair

Journal Articles

A Noninvasive Approach for Assessing Tumor Hypoxia in Xenografts: Developing a Urinary Marker for Hypoxia

Daniel W. Nelson, Hongbin Cao, Yonghua Zhu, Bulbin Sunar-Reeder, Clara Y.H. Choi, James D. Faix, J. Martin Brown, Albert C. Koong, Amato J. Giaccia, Quynh-Thu Le

Cancer Res (2005) 65 (14): 6151–6158.

https://doi.org/10.1158/0008-5472.CAN-04-2602

Published: 15 July 2005

View article titled, A Noninvasive Approach for Assessing Tumor Hypoxia in Xenografts: Developing a Urinary Marker for Hypoxia

Journal Articles

Genome-Wide Identification of Genes Conferring Resistance to the Anticancer Agents Cisplatin, Oxaliplatin, and Mitomycin C

H. Irene Wu, James A. Brown, Mary J. Dorie, Laura Lazzeroni, J. Martin Brown

Cancer Res (2004) 64 (11): 3940–3948.

https://doi.org/10.1158/0008-5472.CAN-03-3113

Published: 01 June 2004

View article titled, Genome-Wide Identification of Genes Conferring Resistance to the Anticancer Agents Cisplatin, Oxaliplatin, and Mitomycin C

Journal Articles

Proceedings of the Oxygen Homeostasis/Hypoxia Meeting

Cancer Res (2004) 64 (9): 3350–3356.

https://doi.org/10.1158/0008-5472.CAN-03-2611

Published: 03 May 2004

View article titled, Proceedings of the Oxygen Homeostasis/Hypoxia Meeting

Journal Articles

Hierarchical clustering of sensitivity profiles for yeast killing by DNA-damaging agents clusters agents by mechanism and genes by function

James A. Brown, H. Irene Wu, George Deng, Alicia Berger, J. Martin Brown

Cancer Res (2004) 64 (7_Supplement): 908.

Published: 01 April 2004

View article titled, Hierarchical clustering of sensitivity profiles for yeast killing by DNA-damaging agents clusters agents by mechanism and genes by function

Journal Articles

Selective Potentiation of the Hypoxic Cytotoxicity of Tirapazamine by Its 1- N -Oxide Metabolite SR 4317

Bronwyn G. Siim, Frederik B. Pruijn, Joanna R. Sturman, Alison Hogg, Michael P. Hay, J. Martin Brown, William R. Wilson

Cancer Res (2004) 64 (2): 736–742.

https://doi.org/10.1158/0008-5472.CAN-03-2488

Published: 26 January 2004

View article titled, Selective Potentiation of the Hypoxic Cytotoxicity of Tirapazamine by Its 1- <em>N</em> -Oxide Metabolite SR 4317

NARROW

Cell Death Identification in Anticancer Therapy—Letter

Abstract 3348: Tumor irradiation induced a phenotype change of monocytes to facilitate vascular regrowth

Abstract B71: Inhibiting the CSF-1 receptor on tumor-infiltrating monocytes may enhance the efficacy of radiotherapy for glioblastoma multiforme

Abstract A13: Hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis by regulating VEGF and S100A8 production

Abstract 386: Inhibiting the CSF-1 receptor on tumor-infiltrating monocytes may enhance the efficacy of radiotherapy for glioblastoma multiforme.

Abstract 385: Inhibition of recurrences of experimental brain tumors after irradiation by blocking the activity of SDF-1 (CXCL12) using the Spiegelmer® NOX-A12.

Abstract 383: Investigation of endothelial progenitor cells as mediators of radiation resistance.

Deficiency in Mammalian Histone H2B Ubiquitin Ligase Bre1 (Rnf20/Rnf40) Leads to Replication Stress and Chromosomal Instability

Overcoming Hypoxia-Induced Apoptotic Resistance through Combinatorial Inhibition of GSK-3β and CDK1

Abstract #1294: Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A

DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity

Optimized Clostridium-Directed Enzyme Prodrug Therapy Improves the Antitumor Activity of the Novel DNA Cross-Linking Agent PR-104

Role of MMP-9 expressing bone marrow-derived myelomonocytic cells in tumor vasculogenesis.

Homologous Recombination Is the Principal Pathway for the Repair of DNA Damage Induced by Tirapazamine in Mammalian Cells

Yeast Bre1 and Dot1 histone modification enzymes are necessary for efficient homologous recombination repair

A Noninvasive Approach for Assessing Tumor Hypoxia in Xenografts: Developing a Urinary Marker for Hypoxia

Genome-Wide Identification of Genes Conferring Resistance to the Anticancer Agents Cisplatin, Oxaliplatin, and Mitomycin C

Proceedings of the Oxygen Homeostasis/Hypoxia Meeting

Hierarchical clustering of sensitivity profiles for yeast killing by DNA-damaging agents clusters agents by mechanism and genes by function

Selective Potentiation of the Hypoxic Cytotoxicity of Tirapazamine by Its 1- N -Oxide Metabolite SR 4317

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