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Isabelle Treilleux
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Journal Articles

Breast Cancer Targeting through Inhibition of the Endoplasmic Reticulum-Based Apoptosis Regulator Nrh/BCL2L10

Adrien Nougarede, Nikolay Popgeorgiev, Loay Kassem, Soleilmane Omarjee, Stephane Borel, Ivan Mikaelian, Jonathan Lopez, Rudy Gadet, Olivier Marcillat, Isabelle Treilleux, Bruno O. Villoutreix, Ruth Rimokh, Germain Gillet
Journal: Cancer Research
Cancer Res (2018) 78 (6): 1404–1417.
https://doi.org/10.1158/0008-5472.CAN-17-0846
Published: 14 March 2018
View article titled, Breast Cancer Targeting through Inhibition of the Endoplasmic Reticulum-Based Apoptosis Regulator Nrh/BCL2L10
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Includes: Multimedia, Supplementary data
Journal Articles

Abstract 5015: Innovative and predictive models against breast cancer

Olivier Duchamp, Severine Tabone-Eglinger, Caroline Mignard, Isabelle Goddard, Alain Bruno, Maia Chanrion, Loreley Calvet, Olivier Degoul, Kevin Dhondt, Liliane Goetsch, Julie Miralves, Christophe Lautrette, Cindy Pensec, Françoise Le Vacon, Isabelle Treilleux, Laurent Arnould, Philippe Vaglio, Grégoire Prevost, Olivier Tredan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5015.
https://doi.org/10.1158/1538-7445.AM2017-5015
Published: 01 July 2017
View article titled, Abstract 5015: Innovative and predictive models against breast cancer
Journal Articles

Abstract P3-06-07: Alterations of intratumoral signalling in breast cancer patients receiving pre-operative trastuzumab alone or combined with everolimus

Jean-Louis Merlin, Maeva Lion, Jennifer Wong, Thomas Bachelot, Fabrice Andre, Isabelle Treilleux, Delphine Loussouarn, Jacques Bonneterre, Maria Rios, Véronique Dieras, Marta Jimenez, Agnès Leroux, Mario Campone
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P3-06-07.
https://doi.org/10.1158/1538-7445.SABCS14-P3-06-07
Published: 01 May 2015
View article titled, Abstract P3-06-07: Alterations of intratumoral signalling in breast cancer patients receiving pre-operative trastuzumab alone or combined with everolimus
Journal Articles

Abstract P4-11-23: Membranous ERα-36 expression is an independent predictor of poor prognosis in operable breast cancer

Loay Kassem, Soleilmane Omarjee, Sylvie Chabaud, Emilie Lavergne, Christelle Faure, Frédéric Beurrier, Olivier Tredan, Laura Corbo, Isabelle Treilleux, Muriel Le Romancer
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P4-11-23.
https://doi.org/10.1158/1538-7445.SABCS14-P4-11-23
Published: 01 May 2015
View article titled, Abstract P4-11-23: Membranous ERα-36 expression is an independent predictor of poor prognosis in operable breast cancer
Journal Articles

Abstract P4-11-24: TIF1[gamma] interacts with the TGFβ1/SMAD4 signaling leading to poorer outcome in operable breast cancer

Loay Kassem, Laurent Fattet, Jonathan Lopez, Goulvent Thibault, Emilie Lavergne, Sylvie Chabaud, Nicolas Carrabin, Nicolas Chopin, Thomas Bachelot, Germain Gillet, Isabelle Treilleux, Ruth Rimohk
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P4-11-24.
https://doi.org/10.1158/1538-7445.SABCS14-P4-11-24
Published: 01 May 2015
View article titled, Abstract P4-11-24: TIF1[gamma] interacts with the TGFβ1/SMAD4 signaling leading to poorer outcome in operable breast cancer
Journal Articles

Abstract 1109: The antimicrobial peptide LL37 activates plasmacytoid dendritic cells in breast cancer

Nelly Vey, Elena Blanc, Vanja Sisirak, Sandra Thys, Céline Le Beux, Nadège Goutagny, Isabelle Treilleux, Aurélien Marabelle, Jean-Yves Blay, Christophe Caux, Nathalie Bendriss-Vermare
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1109.
https://doi.org/10.1158/1538-7445.AM2014-1109
Published: 01 October 2014
View article titled, Abstract 1109: The antimicrobial peptide LL37 activates plasmacytoid dendritic cells in breast cancer
Journal Articles

Abstract 2780: Tyro3 and Axl receptors tyrosine kinase as potential therapeutic targets in leiomyosarcoma

Carmela Dantas-Barbosa, François Le Loarer, Marta Mendiola, Isabelle Treilleux, Frederic Chibon, Hyba E. Sayadi, Jean Michel Coindre, Laurent Alberti, Jean-Yves Blay
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2780.
https://doi.org/10.1158/1538-7445.AM2014-2780
Published: 01 October 2014
View article titled, Abstract 2780: Tyro3 and Axl receptors tyrosine kinase as potential therapeutic targets in leiomyosarcoma
Journal Articles

Abstract LB-253: A comprehensive evaluation of immune checkpoints ligands (ICPLs) in more than 1,000 cancer cell lines (CCLs) identifies specific expression patterns

Aurélie Swalduz, Jean-Philippe Foy, Xiaojun Jiang, Roberto Incitti, Sylvie Chabaud, David Pérol, Jean-Yves Blay, Olivier Trédan, Isabelle Treilleux, Aurélien Marabelle, Maurice Pérol, Christophe Caux, Pierre Saintigny
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-253.
https://doi.org/10.1158/1538-7445.AM2014-LB-253
Published: 01 October 2014
View article titled, Abstract LB-253: A comprehensive evaluation of immune checkpoints ligands (ICPLs) in more than 1,000 cancer cell lines (CCLs) identifies specific expression patterns
Journal Articles

Tumor Promotion by Intratumoral Plasmacytoid Dendritic Cells Is Reversed by TLR7 Ligand Treatment

Isabelle Le Mercier, Dominique Poujol, Amélien Sanlaville, Vanja Sisirak, Michael Gobert, Isabelle Durand, Bertrand Dubois, Isabelle Treilleux, Jacqueline Marvel, Jaromir Vlach, Jean-Yves Blay, Nathalie Bendriss-Vermare, Christophe Caux, Isabelle Puisieux, Nadège Goutagny
Journal: Cancer Research
Cancer Res (2013) 73 (15): 4629–4640.
https://doi.org/10.1158/0008-5472.CAN-12-3058
Published: 31 July 2013
View article titled, Tumor Promotion by Intratumoral Plasmacytoid Dendritic Cells Is Reversed by TLR7 Ligand Treatment
Open the PDF for Tumor Promotion by Intratumoral Plasmacytoid Dendritic Cells Is Reversed by TLR7 Ligand Treatment in another window
Includes: Supplementary data
Journal Articles

Abstract 3480: Impact of a second opinion for sex cord stromal tumors through expression and molecular analysis of FOXL2: a study of the GINECO group and TMRO network.

Thibaut Goulvent, Denis Maillet, Ruth Rimokh, Philippe Cassier, Marie-Cecile Vacher-Lavenu, Pierre Meeus, Patricia Pautier, Pierre Duvillard, Jerome Alexandre, Eric Pujade-Laurraine, Mojgan Devouassoux-Shisheboran, Isabelle Treilleux, Isabelle Ray-coquard
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3480.
https://doi.org/10.1158/1538-7445.AM2013-3480
Published: 15 April 2013
View article titled, Abstract 3480: Impact of a second opinion for sex cord stromal tumors through expression and molecular analysis of FOXL2: a study of the GINECO group and TMRO network.
Journal Articles

ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells

Julien Faget, Nathalie Bendriss-Vermare, Michael Gobert, Isabelle Durand, Daniel Olive, Cathy Biota, Thomas Bachelot, Isabelle Treilleux, Sophie Goddard-Leon, Emilie Lavergne, Sylvie Chabaud, Jean Yves Blay, Christophe Caux, Christine Ménétrier-Caux
Journal: Cancer Research
Cancer Res (2012) 72 (23): 6130–6141.
https://doi.org/10.1158/0008-5472.CAN-12-2409
Published: 29 November 2012
View article titled, ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4<sup>+</sup> T Cells
Open the PDF for ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4<sup>+</sup> T Cells in another window
Includes: Supplementary data
Journal Articles

Impaired IFN-α Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression

Vanja Sisirak, Julien Faget, Michael Gobert, Nadège Goutagny, Nelly Vey, Isabelle Treilleux, Sarah Renaudineau, Gaelle Poyet, Sana Intidhar Labidi-Galy, Sophie Goddard-Leon, Isabelle Durand, Isabelle Le Mercier, Agathe Bajard, Thomas Bachelot, Alain Puisieux, Isabelle Puisieux, Jean-Yves Blay, Christine Ménétrier-Caux, Christophe Caux, Nathalie Bendriss-Vermare
Journal: Cancer Research
Cancer Res (2012) 72 (20): 5188–5197.
https://doi.org/10.1158/0008-5472.CAN-11-3468
Published: 14 October 2012
View article titled, Impaired IFN-α Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression
Open the PDF for Impaired IFN-α Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression in another window
Includes: Supplementary data
Journal Articles

ZNF217 Is a Marker of Poor Prognosis in Breast Cancer That Drives Epithelial–Mesenchymal Transition and Invasion

Julie A. Vendrell, Aurélie Thollet, Nhan T. Nguyen, Sandra E. Ghayad, Stéphanie Vinot, Ivan Bièche, Evelyne Grisard, Véronique Josserand, Jean-Luc Coll, Pierre Roux, Laura Corbo, Isabelle Treilleux, Ruth Rimokh, Pascale A. Cohen
Journal: Cancer Research
Cancer Res (2012) 72 (14): 3593–3606.
https://doi.org/10.1158/0008-5472.CAN-11-3095
Published: 15 July 2012
View article titled, ZNF217 Is a Marker of Poor Prognosis in Breast Cancer That Drives Epithelial–Mesenchymal Transition and Invasion
Open the PDF for ZNF217 Is a Marker of Poor Prognosis in Breast Cancer That Drives Epithelial–Mesenchymal Transition and Invasion in another window
Includes: Supplementary data
Journal Articles

Abstract 5402: Functionally altered plasmacytoid DC in breast tumor environment play a central role in Treg and Tr1-like expansion through ICOS engagement

Julien Faget, Nathalie Bendriss-Vermare, Thomas Bachelot, Vanja Sisirak, Mickael Gobert, Isabelle Durand, Catherine Biota, Isabelle Treilleux, Sophie Goddard-Léon, Jean-Yves Blay, Daniel Olive, Christophe Caux, Christine Ménétrier-Caux
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5402.
https://doi.org/10.1158/1538-7445.AM2012-5402
Published: 15 April 2012
View article titled, Abstract 5402: Functionally altered plasmacytoid DC in breast tumor environment play a central role in Treg and Tr1-like expansion through ICOS engagement
Journal Articles

Early Detection of Tumor Cells by Innate Immune Cells Leads to Treg Recruitment through CCL22 Production by Tumor Cells

Julien Faget, Cathy Biota, Thomas Bachelot, Michael Gobert, Isabelle Treilleux, Nadège Goutagny, Isabelle Durand, Sophie Léon-Goddard, Jean Yves Blay, Christophe Caux, Christine Ménétrier-Caux
Journal: Cancer Research
Cancer Res (2011) 71 (19): 6143–6152.
https://doi.org/10.1158/0008-5472.CAN-11-0573
Published: 29 September 2011
View article titled, Early Detection of Tumor Cells by Innate Immune Cells Leads to T<sub>reg</sub> Recruitment through CCL22 Production by Tumor Cells
Open the PDF for Early Detection of Tumor Cells by Innate Immune Cells Leads to T<sub>reg</sub> Recruitment through CCL22 Production by Tumor Cells in another window
Includes: Supplementary data
Journal Articles

Quantitative and Functional Alterations of Plasmacytoid Dendritic Cells Contribute to Immune Tolerance in Ovarian Cancer

Sana Intidhar Labidi-Galy, Vanja Sisirak, Pierre Meeus, Michael Gobert, Isabelle Treilleux, Agathe Bajard, Jean-Damien Combes, Julien Faget, François Mithieux, Alexandre Cassignol, Olivier Tredan, Isabelle Durand, Christine Ménétrier-Caux, Christophe Caux, Jean-Yves Blay, Isabelle Ray-Coquard, Nathalie Bendriss-Vermare
Journal: Cancer Research
Cancer Res (2011) 71 (16): 5423–5434.
https://doi.org/10.1158/0008-5472.CAN-11-0367
Published: 11 August 2011
View article titled, Quantitative and Functional Alterations of Plasmacytoid Dendritic Cells Contribute to Immune Tolerance in Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Abstract 1442: Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype

Caroline Moyret-Lalle, Gael Grelier, Christine Lasset, Nicolas Voirin, Sylvie Chabaud, Isabelle Treilleux, Alain Puisieux
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1442.
https://doi.org/10.1158/1538-7445.AM10-1442
Published: 15 April 2010
View article titled, Abstract 1442: Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype
Journal Articles

Abstract 1341: Early detection of tumor cells by innate immune cells leads to Treg recruitment through CCL22 production by tumor cells

Julien Faget, Cathy Biota, Thomas Bachelot, Michael Gobert, Colette Dezutter-Dambuyant, Isabelle Treilleux, Sophie Goddard-Leon, Jean Yves Blay, Christophe Caux, Christine Menetrier-Caux
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1341.
https://doi.org/10.1158/1538-7445.AM10-1341
Published: 15 April 2010
View article titled, Abstract 1341: Early detection of tumor cells by innate immune cells leads to Treg recruitment through CCL22 production by tumor cells
Journal Articles

Abstract 1910: Infiltration of ovarian carcinoma by altered plasmacytoid dendritic cells could contribute to local immune tolerance

Sana Intidhar Labidi-Galy, Isabelle Ray-Coquard, Vanja Sisirak, Isabelle Treilleux, Pierre Meeus, François Mithieux, Alexandre Cassignol, François Bouchard, Philippe Gabelle, Jean-Paul Guastalla, Christine Ménetrier-Caux, Christophe Caux, Nathalie Bendriss-Vermare
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1910.
https://doi.org/10.1158/1538-7445.AM10-1910
Published: 15 April 2010
View article titled, Abstract 1910: Infiltration of ovarian carcinoma by altered plasmacytoid dendritic cells could contribute to local immune tolerance
Journal Articles

Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

Michael Gobert, Isabelle Treilleux, Nathalie Bendriss-Vermare, Thomas Bachelot, Sophie Goddard-Leon, Vanessa Arfi, Cathy Biota, Anne Claire Doffin, Isabelle Durand, Daniel Olive, Solène Perez, Nicolas Pasqual, Christelle Faure, Isabelle Ray-Coquard, Alain Puisieux, Christophe Caux, Jean-Yves Blay, Christine Ménétrier-Caux
Journal: Cancer Research
Cancer Res (2009) 69 (5): 2000–2009.
https://doi.org/10.1158/0008-5472.CAN-08-2360
Published: 02 March 2009
View article titled, Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome
Open the PDF for Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome in another window
Includes: Supplementary data