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Isabella Manni
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Journal Articles

Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism

Rosanna Dattilo, Carla Mottini, Emanuela Camera, Alessia Lamolinara, Noam Auslander, Ginevra Doglioni, Michela Muscolini, Wei Tang, Melanie Planque, Cristiana Ercolani, Simonetta Buglioni, Isabella Manni, Daniela Trisciuoglio, Alessandra Boe, Sveva Grande, Anna Maria Luciani, Manuela Iezzi, Gennaro Ciliberto, Stefan Ambs, Ruggero De Maria, Sarah-Maria Fendt, Eytan Ruppin, Luca Cardone
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (19): 4087–4102.
https://doi.org/10.1158/0008-5472.CAN-19-1184
Published: 02 October 2020
View articletitled, Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism
Open the PDF for Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism in another window
Includes: Supplementary data
Journal Articles

Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma

Carla Mottini, Hideo Tomihara, Diego Carrella, Alessia Lamolinara, Manuela Iezzi, Justin K. Huang, Carla A. Amoreo, Simonetta Buglioni, Isabella Manni, Frederick S. Robinson, Rosalba Minelli, Ya'an Kang, Jason B. Fleming, Michael P. Kim, Christopher A. Bristow, Daniela Trisciuoglio, Antonella Iuliano, Donatella Del Bufalo, Diego Di Bernardo, Davide Melisi, Giulio F. Draetta, Gennaro Ciliberto, Alessandro Carugo, Luca Cardone
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (21): 5612–5625.
https://doi.org/10.1158/0008-5472.CAN-19-0187
Published: 01 November 2019
View articletitled, Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma
Open the PDF for Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Targeting the MDM2/MDM4 Interaction Interface as a Promising Approach for p53 Reactivation Therapy

Marsha Pellegrino, Francesca Mancini, Rossella Lucà, Alice Coletti, Nicola Giacchè, Isabella Manni, Ivan Arisi, Fulvio Florenzano, Emanuela Teveroni, Marianna Buttarelli, Laura Fici, Rossella Brandi, Tiziana Bruno, Maurizio Fanciulli, Mara D'Onofrio, Giulia Piaggio, Roberto Pellicciari, Alfredo Pontecorvi, Jean Christophe Marine, Antonio Macchiarulo, Fabiola Moretti
Journal: Cancer Research
Cancer Res (2015) 75 (21): 4560–4572.
https://doi.org/10.1158/0008-5472.CAN-15-0439
Published: 01 November 2015
View articletitled, Targeting the MDM2/MDM4 Interaction Interface as a Promising Approach for p53 Reactivation Therapy
Open the PDF for Targeting the MDM2/MDM4 Interaction Interface as a Promising Approach for p53 Reactivation Therapy in another window
Includes: Supplementary data
Journal Articles

Abstract 4416: A reporter mouse to measure drug myelotoxicity in time.

Nicoletta Rizzi, Isabella Manni, Laura Mancini, Chiara Roncoroni, Electra Brunialti, Paolo Oliva, Maria Pia Gentileschi, Stefano Di Giovine, Enrico A. Pesenti, Giulia Piaggio, Adriana Maggi, Paolo Ciana
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4416.
https://doi.org/10.1158/1538-7445.AM2013-4416
Published: 15 April 2013
View articletitled, Abstract 4416: A reporter mouse to measure drug myelotoxicity in time.
Journal Articles

Transcription Factor NF-Y Induces Apoptosis in Cells Expressing Wild-Type p53 through E2F1 Upregulation and p53 Activation

Aymone Gurtner, Paola Fuschi, Fabio Martelli, Isabella Manni, Simona Artuso, Giacoma Simonte, Valeria Ambrosino, Annalisa Antonini, Valentina Folgiero, Rita Falcioni, Ada Sacchi, Giulia Piaggio
Journal: Cancer Research
Cancer Res (2010) 70 (23): 9711–9720.
https://doi.org/10.1158/0008-5472.CAN-10-0721
Published: 06 December 2010
View articletitled, Transcription Factor NF-Y Induces Apoptosis in Cells Expressing Wild-Type p53 through E2F1 Upregulation and p53 Activation
Open the PDF for Transcription Factor NF-Y Induces Apoptosis in Cells Expressing Wild-Type p53 through E2F1 Upregulation and p53 Activation in another window
Includes: Supplementary data