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Igor Vivanco
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Journal Articles

Abstract 7196: Evaluation of nab-sirolimus in combination with fulvestrant or PI3K pathway inhibitors to overcome resistance in breast cancer cell lines

Khine Nyein Myint, Sean Wallace, Shihe Hou, Maria Zalath, Brian McMorran, Andrew Kwon, Igor Vivanco
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7196.
https://doi.org/10.1158/1538-7445.AM2024-7196
Published: 22 March 2024
View article titled, Abstract 7196: Evaluation of <em>nab</em>-sirolimus in combination with fulvestrant or PI3K pathway inhibitors to overcome resistance in breast cancer cell lines
Journal Articles

Abstract 632: AKT supports cancer cell survival through modulation of cholesterol homeostasis

Igor Vivanco, Khine N. Myint, Sean Wallace, Glorianne Lazaro, Eleftherios Kostaras, Nikolaos Palaskas
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 632.
https://doi.org/10.1158/1538-7445.AM2024-632
Published: 22 March 2024
View article titled, Abstract 632: AKT supports cancer cell survival through modulation of cholesterol homeostasis
Journal Articles

Abstract CT120: Results of the glioblastoma multiforme (GBM) cohort of phase 1 trial Ice-CAP (NCT03673787): Preliminary evidence of antitumour activity of Ipatasertib (Ipa) and Atezolizumab (A) in patients (pts) with PTEN loss

Crescens Tiu, Andrea Biondo, Liam C. Welsh, Timothy L. Jones, Anna Zachariou, Toby Prout, Alison J. Turner, Robert Daly, Igor Vivanco, Christina Yap, Ben Jenkins, Mateus Crespo, Ruth Riisnaes, Suzanne Carreira, Bora Gurel, Nina Tunariu, Anna Minchom, Udai Banerji, Johann S. de Bono, Juanita S. Lopez
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT120.
https://doi.org/10.1158/1538-7445.AM2021-CT120
Published: 01 July 2021
View article titled, Abstract CT120: Results of the glioblastoma multiforme (GBM) cohort of phase 1 trial Ice-CAP (NCT03673787): Preliminary evidence of antitumour activity of Ipatasertib (Ipa) and Atezolizumab (A) in patients (pts) with PTEN loss
Journal Articles

Abstract CT140: Proof-of-concept evidence of immune modulation by blockade of the phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway in the phase I dose escalation study of Ipatasertib (Ipa) in combination with atezolizumab (A) in patients (pts) with advanced solid tumors (Ice-CAP)

Juanita S. Lopez, Andrea Biondo, Crescens Tiu, Mariana Scaranti, Malaka Ameratunga, Anna Zachariou, Alison Turner, Nina Tunariu, Toby Prout, Mona Parmar, Hannah Badham, Karen Swales, Wei Yuan, Ricardo Morilla, Mateus Crespo, Rob Daly, Ines Figueiredo, Bora Gurel, Rita Pereira, Ruth Riisnaes, Igor Vivanco, Anna Minchom, Ben Jenkins, Christina Yap, Udai Banerji, Johann De Bono
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT140.
https://doi.org/10.1158/1538-7445.AM2020-CT140
Published: 15 August 2020
View article titled, Abstract CT140: Proof-of-concept evidence of immune modulation by blockade of the phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway in the phase I dose escalation study of Ipatasertib (Ipa) in combination with atezolizumab (A) in patients (pts) with advanced solid tumors (Ice-CAP)
Journal Articles

Abstract 1032: Identification of Ran binding protein 6 as a novel negative regulator of EGFR and candidate tumor suppressor in glioblastoma

Wan-Ying Hsieh, Barbara Oldrini, Hediye Erdjument-Bromage, Paolo Codega, Maria S. Carro, Igor Vivanco, Dan Rohle, Carl Campos, Craig Bielski, Barry Taylor, Paul Tempst, Massimo Squatrito, Ingo K. Mellinghoff
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1032.
https://doi.org/10.1158/1538-7445.AM2017-1032
Published: 01 July 2017
View article titled, Abstract 1032: Identification of Ran binding protein 6 as a novel negative regulator of EGFR and candidate tumor suppressor in glioblastoma
Journal Articles

Abstract #4217: EGFR T790M decreases growth potential of lung tumor cells with drug-sensitive EGFR mutant alleles in the absence of drug selection

Juliann Chmielecki, Jasmine Foo, Romel Somwar, Lucia Regales, Igor Vivanco, Ronglai Shen, Franziska Michor, William Pao
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4217.
Published: 01 May 2009
View article titled, Abstract #4217: EGFR T790M decreases growth potential of lung tumor cells with drug-sensitive <em>EGFR</em> mutant alleles in the absence of drug selection
Journal Articles

Murine Cell Lines Derived from Pten Null Prostate Cancer Show the Critical Role of PTEN in Hormone Refractory Prostate Cancer Development

Jing Jiao, Shunyou Wang, Rong Qiao, Igor Vivanco, Philip A. Watson, Charles L. Sawyers, Hong Wu
Journal: Cancer Research
Cancer Res (2007) 67 (13): 6083–6091.
https://doi.org/10.1158/0008-5472.CAN-06-4202
Published: 06 July 2007
View article titled, Murine Cell Lines Derived from <em>Pten</em> Null Prostate Cancer Show the Critical Role of PTEN in Hormone Refractory Prostate Cancer Development
Open the PDF for Murine Cell Lines Derived from <em>Pten</em> Null Prostate Cancer Show the Critical Role of PTEN in Hormone Refractory Prostate Cancer Development in another window
Includes: Supplementary data
Journal Articles

Novel murine prostate cancer cell lines provide insight into PTEN’s dosage effect on tumorigenesis and androgen responsiveness

Jing Jiao, shunyou wang, rong qiao, Igor Vivanco, Philip Watson, Charles Sawyers, Hong Wu
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 5257.
Published: 01 May 2007
View article titled, Novel murine prostate cancer cell lines provide insight into PTEN’s dosage effect on tumorigenesis and androgen responsiveness
Journal Articles

Mammalian Target of Rapamycin Inhibition Promotes Response to Epidermal Growth Factor Receptor Kinase Inhibitors in PTEN-Deficient and PTEN-Intact Glioblastoma Cells

Maria Y. Wang, Kan V. Lu, Shaojun Zhu, Ederlyn Q. Dia, Igor Vivanco, Gregory M. Shackleford, Webster K. Cavenee, Ingo K. Mellinghoff, Timothy F. Cloughesy, Charles L. Sawyers, Paul S. Mischel
Journal: Cancer Research
Cancer Res (2006) 66 (16): 7864–7869.
https://doi.org/10.1158/0008-5472.CAN-04-4392
Published: 15 August 2006
View article titled, Mammalian Target of Rapamycin Inhibition Promotes Response to Epidermal Growth Factor Receptor Kinase Inhibitors in PTEN-Deficient and PTEN-Intact Glioblastoma Cells
Open the PDF for Mammalian Target of Rapamycin Inhibition Promotes Response to Epidermal Growth Factor Receptor Kinase Inhibitors in PTEN-Deficient and PTEN-Intact Glioblastoma Cells in another window
Includes: Supplementary data
Journal Articles

Catalytic Cleavage of the Androgen-regulated TMPRSS2 Protease Results in Its Secretion by Prostate and Prostate Cancer Epithelia

Daniel E. H. Afar, Igor Vivanco, Rene S. Hubert, James Kuo, Emily Chen, Douglas C. Saffran, Arthur B. Raitano, Aya Jakobovits
Journal: Cancer Research
Cancer Res (2001) 61 (4): 1686–1692.
Published: 02 February 2001
View article titled, Catalytic Cleavage of the Androgen-regulated TMPRSS2 Protease Results in Its Secretion by Prostate and Prostate Cancer Epithelia
Open the PDF for Catalytic Cleavage of the Androgen-regulated TMPRSS2 Protease Results in Its Secretion by Prostate and Prostate Cancer Epithelia in another window