Page 1 | Search Results | Cancer Research | American Association for Cancer Research

1-20 of 33

Sort by

Sort Order Select

Journal Articles

Abstract 5018: PROTAC degraders of CDK8/CDK19 Mediator kinases potently suppress multiple myeloma proliferation

Li Zhang, Jing Li, Charles E. Dowling, Eugenia V. Broude, Igor B. Roninson, Campbell McInnes, Mengqian Chen

Cancer Res (2023) 83 (7_Supplement): 5018.

https://doi.org/10.1158/1538-7445.AM2023-5018

Published: 04 April 2023

View article titled, Abstract 5018: PROTAC degraders of CDK8/CDK19 Mediator kinases potently suppress multiple myeloma proliferation

Journal Articles

Abstract 2357: Inhibition of CDK8/19 mediator kinase suppresses primary and metastatic growth of castration-resistant prostate cancer

Jing Li, Thomas Hilimire, Chen Cheng, Eugenia V. Broude, Yueying Liu, Michael B. Lilly, Yusuke Shiozawa, George Wilding, Igor B. Roninson, Mengqian Chen

Cancer Res (2022) 82 (12_Supplement): 2357.

https://doi.org/10.1158/1538-7445.AM2022-2357

Published: 15 June 2022

View article titled, Abstract 2357: Inhibition of CDK8/19 mediator kinase suppresses primary and metastatic growth of castration-resistant prostate cancer

Journal Articles

Abstract 6003: Developing Mediator kinase deficient mouse models of CDK8/19 inhibitor therapy

Vladic Mogila, Alexandra A. Bruter, Ekaterina A. Varlamova, Diana S. Korshunova, Victor V. Tatarskiy, Aleksander A. Shtil, Igor B. Roninson

Cancer Res (2022) 82 (12_Supplement): 6003.

https://doi.org/10.1158/1538-7445.AM2022-6003

Published: 15 June 2022

View article titled, Abstract 6003: Developing Mediator kinase deficient mouse models of CDK8/19 inhibitor therapy

Journal Articles

CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases

Jiaxin Liang, Mengqian Chen, Daniel Hughes, Alexander A. Chumanevich, Serena Altilia, Vimala Kaza, Chang-Uk Lim, Hippokratis Kiaris, Karthikeyan Mythreye, Maria Marjorette Pena, Eugenia V. Broude, Igor B. Roninson

Cancer Res (2018) 78 (23): 6594–6606.

https://doi.org/10.1158/0008-5472.CAN-18-1583

Published: 03 December 2018

View article titled, CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases

Includes: Supplementary data

Journal Articles

Abstract 4896: Role of CDK8 in colon cancer hepatic metastasis

Jiaxin Liang, Mengqian Chen, Mythreye Karthikeyan, M. Marjorette Pena, Daniel Hughes, Vimala Kaza, Chang-Uk Lim, Eugenia Broude, Igor B. Roninson

Cancer Res (2017) 77 (13_Supplement): 4896.

https://doi.org/10.1158/1538-7445.AM2017-4896

Published: 01 July 2017

View article titled, Abstract 4896: Role of CDK8 in colon cancer hepatic metastasis

Journal Articles

Abstract P4-15-13: CDK8 inhibition potentiates anti-ER and anti-HER2 therapies in breast cancer

Martina S McDermott, Chang-uk Lim, Mengqian Chen, Alexander Chumanevich, James F Catroppo, Balazs Gyorffy, David Oliver, Igor B Roninson, Eugenia V Broude

Cancer Res (2015) 75 (9_Supplement): P4-15-13.

https://doi.org/10.1158/1538-7445.SABCS14-P4-15-13

Published: 01 May 2015

View article titled, Abstract P4-15-13: CDK8 inhibition potentiates anti-ER and anti-HER2 therapies in breast cancer

Journal Articles

Abstract PR08: Targeting tumor microenvironment with selective small-molecule inhibitors of CDK8/19

Donald C. Porter, Mengqian Chen, Jiaxin Liang, Vimala Kaza, Alexander Chumanevich, Serena Altilia, Elena Farmaki, Marj Pena, Gary P. Schools, Ioulia Chatzistamou, Lawrence T. Friedhoff, Mark P. Wentland, Eugenia V. Broude, Hippokratis Kiaris, Igor B. Roninson

Cancer Res (2015) 75 (1_Supplement): PR08.

https://doi.org/10.1158/1538-7445.CHTME14-PR08

Published: 12 January 2015

View article titled, Abstract PR08: Targeting tumor microenvironment with selective small-molecule inhibitors of CDK8/19

Journal Articles

Abstract 4883: CDK8: A new druggable mediator of NFκB activity

Mengqian Chen, Martina McDermott, Zhengguan Yang, Jiaxin Liang, Gary P. Schools, Chang-uk Lim, Tao Lu, Stark R. George, Deborah K. West, Donald C. Porter, Eugenia V. Broude, Igor B. Roninson

Cancer Res (2014) 74 (19_Supplement): 4883.

https://doi.org/10.1158/1538-7445.AM2014-4883

Published: 01 October 2014

View article titled, Abstract 4883: CDK8: A new druggable mediator of NFκB activity

Journal Articles

Abstract 4879: Targeting the seed and the soil of cancers with selective small-molecule inhibitors of CDK8/19: Chemopotentiating, chemopreventive, anti-invasive and anti-metastatic activities

Donald C. Porter, Jiaxin Liang, Vimala Kaza, Alexander A. Chumanevich, Serena Altilia, Elena Farmaki, Mengqian Chen, Gary P. Schools, Ioulia Chatzistamou, Marj M. Pena, Lawrence T. Friedhoff, Mark P. Wentland, Eugenia Broude, Hippokratis Kiaris, Igor B. Roninson

Cancer Res (2014) 74 (19_Supplement): 4879.

https://doi.org/10.1158/1538-7445.AM2014-4879

Published: 01 October 2014

View article titled, Abstract 4879: Targeting the seed and the soil of cancers with selective small-molecule inhibitors of CDK8/19: Chemopotentiating, chemopreventive, anti-invasive and anti-metastatic activities

Journal Articles

Abstract 5104: Identification of cancer-specific COPI inhibitors and their associated apoptotic cell death pathways

David J. Oliver, Anusha Chaparala, Emeka Okafor, Carlos J. Camacho, Alexander S. Doemling, Felix T. Wieland, Igor B. Roninson, Michael Shtutman

Cancer Res (2014) 74 (19_Supplement): 5104.

https://doi.org/10.1158/1538-7445.AM2014-5104

Published: 01 October 2014

View article titled, Abstract 5104: Identification of cancer-specific COPI inhibitors and their associated apoptotic cell death pathways

Journal Articles

Abstract 1820: CDK3: A novel tumor-selective drug target involved in AP1 activation and transcriptional damage response

Donald C. Porter, Christopher Danes, Bey-Dih Chang, Deborah West, Serena Altilia, Lawrence T. Friedhoff, Polo Lam, Maxim Totrov, Ruben Abagyan, Chang-uk Lim, Eugenia V. Broude, Igor B. Roninson

Cancer Res (2012) 72 (8_Supplement): 1820.

https://doi.org/10.1158/1538-7445.AM2012-1820

Published: 15 April 2012

View article titled, Abstract 1820: CDK3: A novel tumor-selective drug target involved in AP1 activation and transcriptional damage response

Journal Articles

Abstract LB-401: The chemosensitizing properties of iniparib in combination with DNA-damaging agents in the MDA-MB-468(−) triple-negative breast cancer (TNBC) cell line

Valeria Ossovskaya, Chang-Uk Lim, Gary Schools, Swathi Kalurupalle, Igor B. Roninson, Eugenia Broude

Cancer Res (2011) 71 (8_Supplement): LB-401.

https://doi.org/10.1158/1538-7445.AM2011-LB-401

Published: 15 April 2011

View article titled, Abstract LB-401: The chemosensitizing properties of iniparib in combination with DNA-damaging agents in the MDA-MB-468(−) triple-negative breast cancer (TNBC) cell line

Journal Articles

Abstract 3022: The identification of novel senescence-associated miRNAs

Rut W. Klinger, Darran P. O'Connor, William M. Gallagher, Igor B. Roninson

Cancer Res (2010) 70 (8_Supplement): 3022.

https://doi.org/10.1158/1538-7445.AM10-3022

Published: 15 April 2010

View article titled, Abstract 3022: The identification of novel senescence-associated miRNAs

Journal Articles

Cell Adhesion Molecule L1 Disrupts E-Cadherin-Containing Adherens Junctions and Increases Scattering and Motility of MCF7 Breast Carcinoma Cells

Michael Shtutman, Elina Levina, Patrice Ohouo, Mirza Baig, Igor B. Roninson

Cancer Res (2006) 66 (23): 11370–11380.

https://doi.org/10.1158/0008-5472.CAN-06-2106

Published: 04 December 2006

View article titled, Cell Adhesion Molecule L1 Disrupts E-Cadherin-Containing Adherens Junctions and Increases Scattering and Motility of MCF7 Breast Carcinoma Cells

Includes: Multimedia, Supplementary data

Journal Articles

Agonist and Antagonist of Retinoic Acid Receptors Cause Similar Changes in Gene Expression and Induce Senescence-like Growth Arrest in MCF-7 Breast Carcinoma Cells

Yuhong Chen, Milos Dokmanovic, Wilfred D. Stein, Robert J. Ardecky, Igor B. Roninson

Cancer Res (2006) 66 (17): 8749–8761.

https://doi.org/10.1158/0008-5472.CAN-06-0581

Published: 01 September 2006

View article titled, Agonist and Antagonist of Retinoic Acid Receptors Cause Similar Changes in Gene Expression and Induce Senescence-like Growth Arrest in MCF-7 Breast Carcinoma Cells

Journal Articles

Isolation and analysis of senescent tumor cells based on sustained activation of BTG1 promoter

Yuhong Chen, Brian M. Davis, Bey-Dih Chang, Igor B. Roninson

Cancer Res (2006) 66 (8_Supplement): 342.

Published: 15 April 2006

View article titled, Isolation and analysis of senescent tumor cells based on sustained activation of BTG1 promoter

Journal Articles

Mitotic spindle checkpoint complex protects tumor cells from undergoing mitotic catastrophe after release from G1 checkpoint arrest

Claire Vivo, Brian M. Davis, Igor B. Roninson, Eugenia V. Broude

Cancer Res (2006) 66 (8_Supplement): 1152–1153.

Published: 15 April 2006

View article titled, Mitotic spindle checkpoint complex protects tumor cells from undergoing mitotic catastrophe after release from G1 checkpoint arrest

Journal Articles

NFκB-responsive genes are differentially regulated in senescent and non-senescent fibroblast cells that are growth arrested by cyclin-dependent kinase inhibitors

Errin L. Lagow, Bey-Dih Chang, Igor B. Roninson

Cancer Res (2006) 66 (8_Supplement): 1173.

Published: 15 April 2006

View article titled, NFκB-responsive genes are differentially regulated in senescent and non-senescent fibroblast cells that are growth arrested by cyclin-dependent kinase inhibitors

Journal Articles

Src Inhibits Adriamycin-Induced Senescence and G₂ Checkpoint Arrest by Blocking the Induction of p21waf1

Arnaud Vigneron, Igor B. Roninson, Erick Gamelin, Olivier Coqueret

Cancer Res (2005) 65 (19): 8927–8935.

https://doi.org/10.1158/0008-5472.CAN-05-0461

Published: 03 October 2005

View article titled, Src Inhibits Adriamycin-Induced Senescence and G2 Checkpoint Arrest by Blocking the Induction of p21waf1

Journal Articles

New flow cytometric procedure for the analysis of drug effects on topoisomerase II-DNA binding

Ikuo Wada, James Mittler, Robert M. Snapka, Igor B. Roninson, Eugenia V. Broude

Cancer Res (2005) 65 (9_Supplement): 934.

Published: 01 May 2005

View article titled, New flow cytometric procedure for the analysis of drug effects on topoisomerase II-DNA binding

Update search

NARROW

Format

Subjects

Journal

Article Type

Issue Section

Date

Availability

Abstract 5018: PROTAC degraders of CDK8/CDK19 Mediator kinases potently suppress multiple myeloma proliferation

Abstract 2357: Inhibition of CDK8/19 mediator kinase suppresses primary and metastatic growth of castration-resistant prostate cancer

Abstract 6003: Developing Mediator kinase deficient mouse models of CDK8/19 inhibitor therapy

CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases

Abstract 4896: Role of CDK8 in colon cancer hepatic metastasis

Abstract P4-15-13: CDK8 inhibition potentiates anti-ER and anti-HER2 therapies in breast cancer

Abstract PR08: Targeting tumor microenvironment with selective small-molecule inhibitors of CDK8/19

Abstract 4883: CDK8: A new druggable mediator of NFκB activity

Abstract 4879: Targeting the seed and the soil of cancers with selective small-molecule inhibitors of CDK8/19: Chemopotentiating, chemopreventive, anti-invasive and anti-metastatic activities

Abstract 5104: Identification of cancer-specific COPI inhibitors and their associated apoptotic cell death pathways

Abstract 1820: CDK3: A novel tumor-selective drug target involved in AP1 activation and transcriptional damage response

Abstract LB-401: The chemosensitizing properties of iniparib in combination with DNA-damaging agents in the MDA-MB-468(−) triple-negative breast cancer (TNBC) cell line

Abstract 3022: The identification of novel senescence-associated miRNAs

Cell Adhesion Molecule L1 Disrupts E-Cadherin-Containing Adherens Junctions and Increases Scattering and Motility of MCF7 Breast Carcinoma Cells

Agonist and Antagonist of Retinoic Acid Receptors Cause Similar Changes in Gene Expression and Induce Senescence-like Growth Arrest in MCF-7 Breast Carcinoma Cells

Isolation and analysis of senescent tumor cells based on sustained activation of BTG1 promoter

Mitotic spindle checkpoint complex protects tumor cells from undergoing mitotic catastrophe after release from G1 checkpoint arrest

NFκB-responsive genes are differentially regulated in senescent and non-senescent fibroblast cells that are growth arrested by cyclin-dependent kinase inhibitors

Src Inhibits Adriamycin-Induced Senescence and G₂ Checkpoint Arrest by Blocking the Induction of p21waf1

New flow cytometric procedure for the analysis of drug effects on topoisomerase II-DNA binding

Email alerts

AACR Journals

Resources

AACR Journals
on Social Media

Update search

Email alerts

AACR Journals

Resources

AACR Journals on Social Media

This Feature Is Available To Subscribers Only

AACR Journals
on Social Media