1-20 of 121
Ignacio Wistuba
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract CT112: AI-powered and manual assessment of PD-L1 are comparable in predicting response to neoadjuvant atezolizumab in patients (pts) with resectable non-squamous, non-small cell lung cancer (NSCLC)

John Abel, Christopher Rivard, Filip Kos, Guillaume Chhor, Yi Liu, Jennifer Giltnane, Sara Hoffman, Murray Resnick, Cyrus Hedvat, Amaro Taylor-Weiner, Farah Khalil, Alan Nicholas, Gregory A. Fishbein, Lynette M. Sholl, Natasha Rekhtman, Stephanie Hennek, Ilan Wapinski, Ann Johnson, Michael Montalto, Katja Schulze, Bruce E. Johnson, David P. Carbone, Konstantin Shilo, Andrew H. Beck, Sanja Dacic, William D. Travis, Ignacio Wistuba
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT112.
DOI: https://doi.org/10.1158/1538-7445.AM2022-CT112
Published: 15 June 2022
View article
Journal Articles

Abstract 4077: Immune suppressive phenotypes and pre-existing bystander T cell repertoire in early-stage lung adenocarcinoma revealed by integrative single-cell profiling

Guangchun Han, Ansam Sinjab, Dapeng Hao, Lorena Gomez Bolanos, Enyu Dai, Luisa Maren Solis, Edwin Parra, Stephen Swisher, Tina Cascone, Boris Sepesi, Junya Fujimoto, Steven Dubinett, Ignacio Wistuba, Christopher Stevenson, Avrum Spira, Humam Kadara, Linghua Wang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4077.
DOI: https://doi.org/10.1158/1538-7445.AM2022-4077
Published: 15 June 2022
View article
Journal Articles

Abstract 6148: Immunogenomic landscape of tumor-infiltrating B and plasma cells in early-stage lung adenocarcinoma

Dapeng Hao, Guangchun Han, Ansam Sinjab, Lorena Gomez Bolanos, Rossana Lazcano Segura, Enyu Dai, Luisa Maren Solis Soto, Edwin Parra, Jennifer Wargo, Stephen Swisher, Tina Cascone, Boris Sepesi, Junya Fujimoto, Steven Dubinett, Ignacio Wistuba, Christopher Stevenson, Avrum Spira, Humam Kadara, Linghua Wang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6148.
DOI: https://doi.org/10.1158/1538-7445.AM2022-6148
Published: 15 June 2022
View article
Journal Articles

Abstract 2113: Suppression of macrophage migration inhibitory factor (MIF) impairs tumor growth and overcomes immunotherapy resistance in KEAP1-deficient NSCLC tumors

Ana Galan-Cobo, Yu Qian, Fuduan Peng, Daniel James McGrail, Sonia Patel, Fahao Zhang, Xiang Zhang, Ferdinandos Skoulidis, Edwin Parra, Minghao Dang, Saxon Rodriguez, Alexandre Reuben, Ignacio Wistuba, Linghua Wang, John Victor Heymach
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2113.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2113
Published: 15 June 2022
View article
Journal Articles

Abstract 2160: MCT4 blockade reverses lactate-mediated immunosuppression in LKB1-deficient NSCLC

Yu Qian, Irene Guijarro, Ana Galan-Cobo, Minghao Dang, Alissa Poteete, Fahao Zhang, Qi Wang, Jing Wang, Edwin Parra, Ferdinandos Skoulidis, Ignacio Wistuba, Svena Verma, Taha Merghoub, Linghua Wang, Jedd Wolchok, Alexandre Reuben, John Heymach
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2160.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2160
Published: 15 June 2022
View article
Journal Articles

Abstract 1974: Immune gene expression signatures associated clinical benefit from nivolumab and ipilimumab for previously treated patients with stage IV squamous cell lung cancer: An immune biomarker analysis of phase III SWOG LungMAP S1400I trial

Dzifa Y. Duose, Jiexin Zhang, Mary Redman, Baili Zhang, Ethan Cerami, James Lindsay, Joyce Yu, Roshni Biswas, Stephen Van Nostrand, Radim Moravec, Rajyalakshmi Luthra, Gheath Al-Atrash, Karen Kelly, Roy Herbst, Ignacio Wistuba, Scott Gettinger, Lyudmila Bazhenova, J. Jack Lee, Jianjun Zhang, Cara Haymaker
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1974.
DOI: https://doi.org/10.1158/1538-7445.AM2022-1974
Published: 15 June 2022
View article
Journal Articles

Abstract 2758: Multiplex immunofluorescence (mIF) reveals differences in tumor immune microenvironment between molecularly-defined subsets of small cell lung cancer

Pedro Rocha, C. Allison Stewart, Edwin Parra, Luisa M. Solis, Carl M. Gay, Robert J. Cardnell, Naohiro Uraoka, Alejandro Francisco-Cruz, Hitoshi Dejima, Yuanxin Xi, Lixia Diao, Jing Wang, Marcelo V. Negrao, Jianjun Zhang, Ignacio Wistuba, Don L. Gibbons, Lauren A. Byers
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2758.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2758
Published: 01 July 2021
View article
Journal Articles

Abstract 560: High levels of baseline ctDNA constitute a poor prognostic factor in progression-free survival in patients receiving neo-adjuvant chemo-immunotherapy: Results from NADIM clinical trial

Mariano Provencio, Roberto Serna-Blasco, Ernest Nadal, Amelia Insa, M. Rosario Garcia-Campelo, Diego Pereiro Corbacho, Manuel Domine, Margarita Majem, Delvys Rodriguez-Abreu, Alex Martinez-Marti, Javier de Castro, Manuel Cobo, Guillermo Lopez-Vivanco, Edel del Barco, Reyes Bernabe, Nuria Viñolas, Isidoro Barneto, Santiago Viteri, Eva Pereira, Ana Royuela, Marta Casarrubios, Clara Salas, Edwin R Parra, Ignacio Wistuba, Virginia Calvo, Raquel Laza-Briviesca, Bartomeu Massuti, Alberto Cruz-Vermudez, Atocha Romero
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 560.
DOI: https://doi.org/10.1158/1538-7445.AM2021-560
Published: 01 July 2021
View article
Journal Articles

Abstract 2679: Immuno-oncology panel optimization for imaging mass cytometry and digital image analysis of tumor tissues

Pedro Rocha, Luisa Solis, Edwin Parra, Ou Shi, Barbara Mino, Vidya C. Sinha, Amanda Rinkenbaugh, Auriole Tamegnon, Mak Duncan, Wei Lu, Mei Jiang, Lakshimi Kakarala, Jared K. Burks, Helen Piwnica-Worms, Cara Haymacker, Michael Teztlaff, Ignacio Wistuba, Alejandro Francisco-Cruz
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2679.
DOI: https://doi.org/10.1158/1538-7445.AM2020-2679
Published: 15 August 2020
View article
Journal Articles

Abstract 1496: Paired, single-cell profiling of circulating tumor cell-derived xenograft models of small cell lung cancer reveals intratumoral heterogeneity and emergence of new cell clusters following treatment relapse

C. Allison Stewart, Carl M. Gay, Yuanxin Xi, Santhosh Sivajothi, Junya Fujimoto, Patrice M. Hartsfield, Hai Tran, Stephen G. Swisher, Jack A. Roth, Jianjun Zhang, Bonnie Glisson, John V. Heymach, Ignacio Wistuba, Paul Robson, Jing Wang, Lauren A. Byers
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1496.
DOI: https://doi.org/10.1158/1538-7445.AM2020-1496
Published: 15 August 2020
View article
Journal Articles

Abstract LB-318: Multi-institutional TSA-amplified Multiplexed Immunofluorescence Reproducibility Evaluation (MITRE study): Reproducibility assessment of an automated multiplexed immunofluorescence slide staining, imaging, and analysis workflow

Clifford Hoyt, Kristin Roman, Liz Engle, Chichung Wang, Carmen Ballesteros-Merino, Shawn M. Jensen, John McGuire, Yi Zheng, Carla Coltharp, Mei Jiang, Justin Lucas, Edwin Parra, Ignacio Wistuba, Darren Locke, Bernard A. Fox, David L. Rimm, Janis Marie Taube
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-318.
DOI: https://doi.org/10.1158/1538-7445.AM2019-LB-318
Published: 01 July 2019
View article
Journal Articles

Abstract 3099: Characterization of bone marrow tumor associated macrophages in patients with chronic lymphocytic leukemia treated with Ibrutinib

Paolo Strati, Ellen Schlette, Luisa Solis Soto, Daniela Duenas, Ignacio Wistuba, Jan Burger
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3099.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3099
Published: 01 July 2019
View article
Journal Articles

Abstract 5028: Characterization of the tumor immune microenvironment in treatment-naïve EGFR-mutant NSCLC uncovers a low IFN-gamma suppressive immune phenotype

Xiuning Le, Marcelo V. Negrao, Alexandre Reuben, Won-Chul Lee, Edwin Parra, Jun Li, Tatiana Karpinets, Carmen Behrens, Boris Sepesi, Ara Vaporiciyan, Jack Roth, Cara Haymaker, Emily Roarty, Jianhua Zhang, Chantale Bernatchez, Jianjun Zhang, Ignacio Wistuba, Don Gibbons, John Heymach
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5028.
DOI: https://doi.org/10.1158/1538-7445.AM2019-5028
Published: 01 July 2019
View article
Journal Articles

Abstract 1948: Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers

Masanori Kawakami, Lisa Maria Mustachio, Lin Zheng, Yulong Chen, Jaime Rodriguez-Canales, Barbara Mino, Jonathan M. Kurie, Jason Roszik, Pamela Andrea Villalobos, Kelsie L. Thu, David W. Cescon, Jennifer Silvester, Ignacio Wistuba, Tak W. Mak, Xi Liu, Ethan Dmitrovsky
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1948.
DOI: https://doi.org/10.1158/1538-7445.AM2018-1948
Published: 01 July 2018
View article
Journal Articles

Abstract 3633: Immunofluorescence profiling of co-expression of multiple immune checkpoints in malignant and tumor infiltrated lymphocytes in non-small cell lung carcinomas using image analysis system

Edwin Roger Parra, Mei Jiang, Jiexin Zhang, Carmen Behrens, Jack Lee, John Victor Heymach, Marie-Andrée Forget, Cara Haymaker, Chantale Bernatchez, Cesar Moran, Jianjun Zhang, Don Gibbons, Ignacio Wistuba
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3633.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3633
Published: 01 July 2018
View article
Journal Articles

Abstract 213: Exome sequencing of paired primary and relapsed small cell lung cancers reveals increased copy number aberration complexity to be associated with disease relapse

Marcelo V. Negrao, Ming Tang, Ying Jin, Yamei Chen, Xiao Hu, Huarong Tang, Haimiao Xu, Kelly Quek, Jianhua Zhang, Xizeng Mao, Xingzhi Song, John V. Heymach, Ignacio Wistuba, Lauren A. Byers, Bonnie S. Glisson, Andrew Futreal, Ming Chen, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 213.
DOI: https://doi.org/10.1158/1538-7445.AM2018-213
Published: 01 July 2018
View article
Journal Articles

Abstract 5172: A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis

Emily Powell, Jiansu Shao, Hector Picon, Christopher Bristow, Zhongqi Ge, Caitlin Grzeskowiak, Michael Peoples, Frederick Robinson, Sabrina Jeter-Jones, Christopher Schlosberg, Fei Yang, Yun Wu, Ignacio Wistuba, Stacy Moulder, Fraser Symmans, Kenneth Scott, John Edwards, Han Liang, Timothy Heffernan, Helen Piwnica-Worms
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5172.
DOI: https://doi.org/10.1158/1538-7445.AM2018-5172
Published: 01 July 2018
View article
Journal Articles

Abstract 4686: T cell repertoire evolution from the normal lung to invasive lung adenocarcinoma

Runzhe Chen, Junya Fujimoto, Alexandre Reuben, Lisha Ying, Xin Hu, Chi-Wan Chow, Jaime Rodriguez Canales, Wenyong Sun, Jinlin Hu, Edwin R. Parra Cuentas, Carmen Behrens, Chang-Jiun Wu, Latasha Little, Curtis Gumbs, Diana Wiesnoski, Guangchun Han, Won-Chul Lee, Paul Scheet, Humam Kadara, Mara Antonoff, Ara A. Vaporciyan, Stephen Swisher, Jianhua Zhang, John Heymach, Waun Ki Hong, Ignacio Wistuba, Andrew Futreal, Dan Su, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4686.
DOI: https://doi.org/10.1158/1538-7445.AM2018-4686
Published: 01 July 2018
View article
Journal Articles

Abstract 2934: Neoadjuvant chemotherapy influence changes of the immune response in non-small cell lung carcinomas immune response in non-small cell lung carcinomas

Edwin Roger Cuentas, Carmen Behrens, Jaime Rodriguez-Canales, Mei Jiang, Apar Pataer, Arelene Correa, Stephen Swisher, Boris Sepesi, Annikka Weissferdt, Neda Kalhor, Jiexin Zhang, Jack Lee, John Heymach, Cesar Moran, Jianjun Zhang, Don Gibbons, Ignacio Wistuba
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2934.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2934
Published: 01 July 2017
View article
Journal Articles

Abstract 627: NLRC5 co-mutations are associated with impaired antigen presentation and immune exclusion in KRAS-mutant lung adenocarcinoma

Ferdinandos Skoulidis, Taghreed Hirz, Xiang Dong Lee, Jaime Rodriguez Canales, Edwin R. Parra, Pan Tong, Carmen Behrens, Vassiliki A. Papadimitrakopoulou, Jing Wang, Ignacio Wistuba, John V. Heymach
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 627.
DOI: https://doi.org/10.1158/1538-7445.AM2017-627
Published: 01 July 2017
View article