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Journal Articles

Abstract 2214: Inhibiting the mevalonate pathway with atorvastatin alters gut microbiota and has potential as an anti-cancer treatment for ovarian cancer

Juliane M. Liberto, Emily Ke, Daniel Labbe, Sabrene Mechergui, Kala Visvanathan, Ie-Ming Shih, Tian-Li Wang

Cancer Res (2025) 85 (8_Supplement_1): 2214.

https://doi.org/10.1158/1538-7445.AM2025-2214

Published: 21 April 2025

View articletitled, Abstract 2214: Inhibiting the mevalonate pathway with atorvastatin alters gut microbiota and has potential as an anti-cancer treatment for ovarian cancer

Journal Articles

Abstract C036: Pharmacological modulation of glutamine metabolism alters macrophage activity and tumor immune responses

Jiawei Fan, Sumeng Qi, Ie-Ming Shih, Tian-Li Wang

Cancer Res (2024) 84 (22_Supplement): C036.

https://doi.org/10.1158/1538-7445.TUMBODY-C036

Published: 17 November 2024

View articletitled, Abstract C036: Pharmacological modulation of glutamine metabolism alters macrophage activity and tumor immune responses

Journal Articles

Dual Inhibition of SYK and EGFR Overcomes Chemoresistance by Inhibiting CDC6 and Blocking DNA Replication

Jayaprakash Mandal, Tiffany Nicole Jones, Juliane Marie Liberto, Stephanie Gaillard, Tian-Li Wang, Ie-Ming Shih

Cancer Res (2024) 84 (22): 3881–3893.

https://doi.org/10.1158/0008-5472.CAN-24-0769

Published: 15 November 2024

View articletitled, Dual Inhibition of SYK and EGFR Overcomes Chemoresistance by Inhibiting CDC6 and Blocking DNA Replication

Includes: Supplementary data

Journal Articles

Abstract 7003: Microfluidic platform for DNA methylation profiling towards early detection of ovarian cancer

Chrissy O'Hersey, Yang Zhao, Thomas R. Pisanic, Tian-Li Wang, Ie-Ming Shih, Tza-Huei Jeff Wang

Cancer Res (2024) 84 (6_Supplement): 7003.

https://doi.org/10.1158/1538-7445.AM2024-7003

Published: 22 March 2024

View articletitled, Abstract 7003: Microfluidic platform for DNA methylation profiling towards early detection of ovarian cancer

Journal Articles

Temozolomide Sensitizes ARID1A-Mutated Cancers to PARP Inhibitors

Zheng-Cheng Yu, Tianhe Li, Ellen Tully, Peng Huang, Chih-Ning Chen, Philipp Oberdoerffer, Stephanie Gaillard, Ie-Ming Shih, Tian-Li Wang

Cancer Res (2023) 83 (16): 2750–2762.

https://doi.org/10.1158/0008-5472.CAN-22-3646

Published: 15 August 2023

View articletitled, Temozolomide Sensitizes ARID1A-Mutated Cancers to PARP Inhibitors

Includes: Supplementary data

Journal Articles

Spatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 during Pathogenesis

Yeh Wang, Peng Huang, Brant G. Wang, Tricia Murdock, Leslie Cope, Fang-Chi Hsu, Tian-Li Wang, Ie-Ming Shih

Cancer Res (2022) 82 (24): 4528–4541.

https://doi.org/10.1158/0008-5472.CAN-22-1620

Published: 16 December 2022

View articletitled, Spatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 during Pathogenesis

Includes: Supplementary data

Journal Articles

Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers

Cancer Res (2020) 80 (20): 4514–4526.

https://doi.org/10.1158/0008-5472.CAN-19-3971

Published: 15 October 2020

View articletitled, Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers

Includes: Supplementary data

Journal Articles

Abstract 2729: Development of a targeted liquid biopsy for early gynecologic cancer detection leads to discovery of a highly prevalent genomic landscape of cancer driver gene mutations in uterine tissue from women without cancer

Cancer Res (2019) 79 (13_Supplement): 2729.

https://doi.org/10.1158/1538-7445.AM2019-2729

Published: 01 July 2019

View articletitled, Abstract 2729: Development of a targeted liquid biopsy for early gynecologic cancer detection leads to discovery of a highly prevalent genomic landscape of cancer driver gene mutations in uterine tissue from women without cancer

Journal Articles

Abstract 2493: Inactivation of ARID1A-SWI/SNF complex alters chromatin compactness at enhancer regions and affects transcription of key tumor signaling circuitry

Yohan Suryo Rahmanto, Xu Shi, Wenjing Shen, Tsutomu Miyamoto, Yu Yu, Xi Chen, Meng-Horng Lee, Vivek Singh, Michele I. Vitolo, Denis Wirtz, Ronny Drapkin, Jianhua Xuan, Ie-Ming Shih, Tian-Li Wang

Cancer Res (2018) 78 (13_Supplement): 2493.

https://doi.org/10.1158/1538-7445.AM2018-2493

Published: 01 July 2018

View articletitled, Abstract 2493: Inactivation of ARID1A-SWI/SNF complex alters chromatin compactness at enhancer regions and affects transcription of key tumor signaling circuitry

Journal Articles

Abstract 1966: A novel small-molecule compound targeting PBX1-DNA interaction impedes cancer cell survival and carboplatin resistance

Yao-An Shen, Jin Jung, Yohan Suryo Rahmanto, Licia Selleri, Ie-Ming Shih, Chi-Mu Chuang, Tian-Li Wang

Cancer Res (2018) 78 (13_Supplement): 1966.

https://doi.org/10.1158/1538-7445.AM2018-1966

Published: 01 July 2018

View articletitled, Abstract 1966: A novel small-molecule compound targeting PBX1-DNA interaction impedes cancer cell survival and carboplatin resistance

Journal Articles

Abstract 3991: Profiling the immune tumor microenvironment in primary and recurrent epithelial ovarian cancer

Laureen S. Ojalvo, Elizabeth D. Thompson, Tian-Li Wang, Alan K. Meeker, Ie-Ming Shih, Amanda N. Fader, Ashley Cimino-Mathews, Leisha A. Emens

Cancer Res (2017) 77 (13_Supplement): 3991.

https://doi.org/10.1158/1538-7445.AM2017-3991

Published: 01 July 2017

View articletitled, Abstract 3991: Profiling the immune tumor microenvironment in primary and recurrent epithelial ovarian cancer

Journal Articles

Ovarian Cancer Chemoresistance Relies on the Stem Cell Reprogramming Factor PBX1

Jin-Gyoung Jung, Ie-Ming Shih, Joon Tae Park, Emily Gerry, Tae Hoen Kim, Ayse Ayhan, Karen Handschuh, Ben Davidson, Amanda N. Fader, Licia Selleri, Tian-Li Wang

Cancer Res (2016) 76 (21): 6351–6361.

https://doi.org/10.1158/0008-5472.CAN-16-0980

Published: 31 October 2016

View articletitled, Ovarian Cancer Chemoresistance Relies on the Stem Cell Reprogramming Factor PBX1

Includes: Supplementary data

Journal Articles

Abstract B30: Targeting EZH2 methyltransferase activity: A novel therapeutic approach to ARID1A-deficient cancer

Benjamin Bitler, Azat Garipov, Ie Ming Shih, Rugang Zhang

Cancer Res (2016) 76 (2_Supplement): B30.

https://doi.org/10.1158/1538-7445.CHROMEPI15-B30

Published: 14 January 2016

View articletitled, Abstract B30: Targeting EZH2 methyltransferase activity: A novel therapeutic approach to ARID1A-deficient cancer

Journal Articles

Abstract A63: Rsf-1, a chromatin remodeling protein, interacts with shelterin protein hRap1 and induces telomere shortening

Ren-Chin Wu, Bin Guan, Yusuke Kobayashi, Tian-Li Wang, Ie-Ming Shih

Cancer Res (2013) 73 (13_Supplement): A63.

https://doi.org/10.1158/1538-7445.CEC13-A63

Published: 13 May 2014

View articletitled, Abstract A63: Rsf-1, a chromatin remodeling protein, interacts with shelterin protein hRap1 and induces telomere shortening

Journal Articles

RSF1 Is a Positive Regulator of NF-κB–Induced Gene Expression Required for Ovarian Cancer Chemoresistance

Yeong-In Yang, Ji-Hye Ahn, Kyung-Tae Lee, Ie-Ming Shih, Jung-Hye Choi

Cancer Res (2014) 74 (8): 2258–2269.

https://doi.org/10.1158/0008-5472.CAN-13-2459

Published: 15 April 2014

View articletitled, RSF1 Is a Positive Regulator of NF-κB–Induced Gene Expression Required for Ovarian Cancer Chemoresistance

Includes: Supplementary data

Journal Articles

Abstract LB-259: Arid1a loss in collaboration with PI3K pathway activation leads to ovarian tumorigenesis in mouse.

Bin Guan, Tian-Li Wang, Ie-Ming Shih

Cancer Res (2013) 73 (8_Supplement): LB-259.

https://doi.org/10.1158/1538-7445.AM2013-LB-259

Published: 15 April 2013

View articletitled, Abstract LB-259: Arid1a loss in collaboration with PI3K pathway activation leads to ovarian tumorigenesis in mouse.

Journal Articles

Abstract 401: Gene expression signatures differentiate primary and metastatic uterine leiomyosarcoma.

Ben Davidson, Vera Maria Abeler, Mette Førsund, Arild Holth, Ie-Ming Shih, Gunnar B. Kristensen, Li Chen, Yanqin Yang, Tian-Li Wang

Cancer Res (2013) 73 (8_Supplement): 401.

https://doi.org/10.1158/1538-7445.AM2013-401

Published: 15 April 2013

View articletitled, Abstract 401: Gene expression signatures differentiate primary and metastatic uterine leiomyosarcoma.

Journal Articles

NAC1 Is an Actin-Binding Protein That Is Essential for Effective Cytokinesis in Cancer Cells

Kai Lee Yap, Stephanie I. Fraley, Michelle M. Thiaville, Natini Jinawath, Kentaro Nakayama, Jianlong Wang, Tian-Li Wang, Denis Wirtz, Ie-Ming Shih

Cancer Res (2012) 72 (16): 4085–4096.

https://doi.org/10.1158/0008-5472.CAN-12-0302

Published: 14 August 2012

View articletitled, NAC1 Is an Actin-Binding Protein That Is Essential for Effective Cytokinesis in Cancer Cells

Includes: Multimedia, Supplementary data

Journal Articles

Dysfunction of Nucleus Accumbens-1 Activates Cellular Senescence and Inhibits Tumor Cell Proliferation and Oncogenesis

Yi Zhang, Yan Cheng, Xingcong Ren, Tsukasa Hori, Kathryn J. Huber-Keener, Li Zhang, Kai Lee Yap, David Liu, Lisa Shantz, Zheng-Hong Qin, Suping Zhang, Jianrong Wang, Hong-Gang Wang, Ie-Ming Shih, Jin-Ming Yang

Cancer Res (2012) 72 (16): 4262–4275.

https://doi.org/10.1158/0008-5472.CAN-12-0139

Published: 14 August 2012

View articletitled, Dysfunction of Nucleus Accumbens-1 Activates Cellular Senescence and Inhibits Tumor Cell Proliferation and Oncogenesis

Includes: Supplementary data

Journal Articles

Defining NOTCH3 Target Genes in Ovarian Cancer

Xu Chen, Michelle M. Thiaville, Li Chen, Alexander Stoeck, Jianhua Xuan, Min Gao, Ie-Ming Shih, Tian-Li Wang

Cancer Res (2012) 72 (9): 2294–2303.

https://doi.org/10.1158/0008-5472.CAN-11-2181

Published: 30 April 2012

View articletitled, Defining NOTCH3 Target Genes in Ovarian Cancer

Includes: Supplementary data

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Abstract 2214: Inhibiting the mevalonate pathway with atorvastatin alters gut microbiota and has potential as an anti-cancer treatment for ovarian cancer

Abstract C036: Pharmacological modulation of glutamine metabolism alters macrophage activity and tumor immune responses

Dual Inhibition of SYK and EGFR Overcomes Chemoresistance by Inhibiting CDC6 and Blocking DNA Replication

Abstract 7003: Microfluidic platform for DNA methylation profiling towards early detection of ovarian cancer

Temozolomide Sensitizes ARID1A-Mutated Cancers to PARP Inhibitors

Spatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 during Pathogenesis

Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers

Abstract 2729: Development of a targeted liquid biopsy for early gynecologic cancer detection leads to discovery of a highly prevalent genomic landscape of cancer driver gene mutations in uterine tissue from women without cancer

Abstract 2493: Inactivation of ARID1A-SWI/SNF complex alters chromatin compactness at enhancer regions and affects transcription of key tumor signaling circuitry

Abstract 1966: A novel small-molecule compound targeting PBX1-DNA interaction impedes cancer cell survival and carboplatin resistance

Abstract 3991: Profiling the immune tumor microenvironment in primary and recurrent epithelial ovarian cancer

Ovarian Cancer Chemoresistance Relies on the Stem Cell Reprogramming Factor PBX1

Abstract B30: Targeting EZH2 methyltransferase activity: A novel therapeutic approach to ARID1A-deficient cancer

Abstract A63: Rsf-1, a chromatin remodeling protein, interacts with shelterin protein hRap1 and induces telomere shortening

RSF1 Is a Positive Regulator of NF-κB–Induced Gene Expression Required for Ovarian Cancer Chemoresistance

Abstract LB-259: Arid1a loss in collaboration with PI3K pathway activation leads to ovarian tumorigenesis in mouse.

Abstract 401: Gene expression signatures differentiate primary and metastatic uterine leiomyosarcoma.

NAC1 Is an Actin-Binding Protein That Is Essential for Effective Cytokinesis in Cancer Cells

Dysfunction of Nucleus Accumbens-1 Activates Cellular Senescence and Inhibits Tumor Cell Proliferation and Oncogenesis

Defining NOTCH3 Target Genes in Ovarian Cancer

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