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Ian R. Judson
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Journal Articles

Histone Deacetylase Inhibition Increases Levels of Choline Kinase α and Phosphocholine Facilitating Noninvasive Imaging in Human Cancers

Mounia Beloueche-Babari, Vaitha Arunan, Helen Troy, Robert H. te Poele, Anne-Christine Wong Te Fong, L. Elizabeth Jackson, Geoffrey S. Payne, John R. Griffiths, Ian R. Judson, Paul Workman, Martin O. Leach, Yuen-Li Chung
Journal: Cancer Research
Cancer Res (2012) 72 (4): 990–1000.
https://doi.org/10.1158/0008-5472.CAN-11-2688
Published: 14 February 2012
View article titled, Histone Deacetylase Inhibition Increases Levels of Choline Kinase α and Phosphocholine Facilitating Noninvasive Imaging in Human Cancers
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Includes: Supplementary data
Journal Articles

Abstract 3788: Autophagy induced by DCA, PI3K inhibition or starvation results in reduced lactate production measured in real-time by DNP 13C MRS

Yuen-Li Chung, Gigin Lin, Helen Troy, Anne-Christine Wong Te Fong, L Elizabeth Jackson, Deborah K. Hill, Matthew Orton, Dow-Mu Koh, Simon P. Robinson, Ian R. Judson, John R. Griffiths, Martin O. Leach, Thomas R. Eykyn
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3788.
https://doi.org/10.1158/1538-7445.AM2011-3788
Published: 15 April 2011
View article titled, Abstract 3788: Autophagy induced by DCA, PI3K inhibition or starvation results in reduced lactate production measured in real-time by DNP 13C MRS
Journal Articles

Phase I study of SR4554 as a non-invasive probe of tumor hypoxia detected by magnetic resonance spectroscopy

Chooi P. Lee, Geoffrey S. Payne, Alain Oregioni, Ruth R. Ruddle, Florence I. Raynaud, David A. Eaton, Kathryn Cross, Michael Tracy, James P. McNamara, Martin O. Leach, Ian R. Judson, Paul Workman
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 232.
Published: 15 April 2006
View article titled, Phase I study of SR4554 as a non-invasive probe of tumor hypoxia detected by magnetic resonance spectroscopy
Journal Articles

Noninvasive Magnetic Resonance Spectroscopic Pharmacodynamic Markers of the Choline Kinase Inhibitor MN58b in Human Carcinoma Models

Nada M.S. Al-Saffar, Helen Troy, Ana Ramírez de Molina, Laura E. Jackson, Basetti Madhu, John R. Griffiths, Martin O. Leach, Paul Workman, Juan C. Lacal, Ian R. Judson, Yuen-Li Chung
Journal: Cancer Research
Cancer Res (2006) 66 (1): 427–434.
https://doi.org/10.1158/0008-5472.CAN-05-1338
Published: 05 January 2006
View article titled, Noninvasive Magnetic Resonance Spectroscopic Pharmacodynamic Markers of the Choline Kinase Inhibitor MN58b in Human Carcinoma Models
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Journal Articles

SR4554 as a non-invasive probe of tumor hypoxia detected by Magnetic Resonance Spectroscopy: Update of a Phase I Trial

Chooi P. Lee, Geoffrey S. Payne, Ruth R. Ruddle, Florence I. Raynaud, Siew K. Tan, Maeli J. Campbell, Michael Tracy, James P. McNamara, Martin O. Leach, Ian R. Judson, Paul Workman
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 897.
Published: 01 May 2005
View article titled, SR4554 as a non-invasive probe of tumor hypoxia detected by Magnetic Resonance Spectroscopy: Update of a Phase I Trial
Journal Articles

Metabolites of 2′-Fluoro-2′-deoxy-d-glucose Detected by 19F Magnetic Resonance Spectroscopy in Vivo Predict Response of Murine RIF-1 Tumors to 5-Fluorouracil1

Paul M. J. McSheehy, Martin O. Leach, Ian R. Judson, John R. Griffiths
Journal: Cancer Research
Cancer Res (2000) 60 (8): 2122–2127.
Published: 01 April 2000
View article titled, Metabolites of 2′-Fluoro-2′-deoxy-<sc>d</sc>-glucose Detected by <sup>19</sup>F Magnetic Resonance Spectroscopy <em>in Vivo</em> Predict Response of Murine RIF-1 Tumors to 5-Fluorouracil1
Open the PDF for Metabolites of 2′-Fluoro-2′-deoxy-<sc>d</sc>-glucose Detected by <sup>19</sup>F Magnetic Resonance Spectroscopy <em>in Vivo</em> Predict Response of Murine RIF-1 Tumors to 5-Fluorouracil1 in another window
Journal Articles

Carbogen Breathing Increases 5-Fluorouracil Uptake and Cytotoxicity in Hypoxic Murine RIF-1 Tumors: A Magnetic Resonance Study in Vivo

Paul M. J. McSheehy, Simon P. Robinson, Agatha S. E. Ojugo, Eric O. Aboagye, Mark B. Cannell, Martin O. Leach, Ian R. Judson, John R. Griffiths
Journal: Cancer Research
Cancer Res (1998) 58 (6): 1185–1194.
Published: 01 March 1998
View article titled, Carbogen Breathing Increases 5-Fluorouracil Uptake and Cytotoxicity in Hypoxic Murine RIF-1 Tumors: A Magnetic Resonance Study <em>in Vivo</em>
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Journal Articles

Idoxifene: Report of a Phase I Study in Patients with Metastatic Breast Cancer

R. Charles Coombes, Ben P. Haynes, Mitchell Dowsett, Mary Quigley, Jacqueline English, Ian R. Judson, Lesley J. Griggs, Gerry A. Potter, Ray McCague, Michael Jarman
Journal: Cancer Research
Cancer Res (1995) 55 (5): 1070–1074.
Published: 01 March 1995
View article titled, Idoxifene: Report of a Phase I Study in Patients with Metastatic Breast Cancer
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Journal Articles

ICI D1694, a Quinazoline Antifolate Thymidylate Synthase Inhibitor That Is a Potent Inhibitor of L1210 Tumor Cell Growth in Vitro and in Vivo: A New Agent for Clinical Study

Ann L. Jackman, Gordon A. Taylor, William Gibson, Rosemary Kimbell, Melody Brown, A. Hilary Calvert, Ian R. Judson, Leslie R. Hughes
Journal: Cancer Research
Cancer Res (1991) 51 (20): 5579–5586.
Published: 01 October 1991
View article titled, ICI D1694, a Quinazoline Antifolate Thymidylate Synthase Inhibitor That Is a Potent Inhibitor of L1210 Tumor Cell Growth <em>in Vitro</em> and <em>in Vivo</em>: A New Agent for Clinical Study
Open the PDF for ICI D1694, a Quinazoline Antifolate Thymidylate Synthase Inhibitor That Is a Potent Inhibitor of L1210 Tumor Cell Growth <em>in Vitro</em> and <em>in Vivo</em>: A New Agent for Clinical Study in another window
Journal Articles

Phase I Trial and Pharmacokinetics of Trimelamol (N2,N4,N6-Trihydroxymethyl-N2,N4,N6-trimethylmelamine)

Ian R. Judson, A. Hilary Calvert, Christine J. Rutty, George Abel, Lindsey A. Gumbrell, Martin A. Graham, Barrie D. Evans, Derry E. V. Wilman, Susan E. Ashley, Fiona Cairnduff
Journal: Cancer Research
Cancer Res (1989) 49 (19): 5475–5479.
Published: 01 October 1989
View article titled, Phase I Trial and Pharmacokinetics of Trimelamol (<em>N</em><sup>2</sup>,<em>N</em><sup>4</sup>,<em>N</em><sup>6</sup>-Trihydroxymethyl-<em>N</em><sup>2</sup>,<em>N</em><sup>4</sup>,<em>N</em><sup>6</sup>-trimethylmelamine)
Open the PDF for Phase I Trial and Pharmacokinetics of Trimelamol (<em>N</em><sup>2</sup>,<em>N</em><sup>4</sup>,<em>N</em><sup>6</sup>-Trihydroxymethyl-<em>N</em><sup>2</sup>,<em>N</em><sup>4</sup>,<em>N</em><sup>6</sup>-trimethylmelamine) in another window