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Ian P. Winters
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Journal Articles

Abstract 1172: Oncogenic context shapes the fitness landscape of tumor suppression

Free
Lily M. Blair, Joseph M. Juan, Lafia Sebastian, Vy B. Tran, Wensheng Nie, Gregory D. Wall, Mehmet Gerceker, Ian K. Lai, Edwin A. Apilado, Gabriel Grenot, David Amar, Giorgia Foggetti, Mariana Do Carmo, Zeynep Ugur, Debbie Deng, Alex Chenchik, Maria Paz Zafra, Lukas E. Dow, Katerina Politi, Jonathan J. MacQuitty, Dmitri A. Petrov, Monte M. Winslow, Michael J. Rosen, Ian P. Winters
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1172.
https://doi.org/10.1158/1538-7445.AM2023-1172
Published: 04 April 2023
View article titled, Abstract 1172: Oncogenic context shapes the fitness landscape of tumor suppression
Journal Articles

Abstract 11: Analysis of 30 million tumor time course reveals that inactivating tumor suppressors produces complex gene-specific, time-dependent growth dynamics

Free
Alissa L. Severson, Joseph Juan, Lafia Sebastian, Vy Tran, Wensheng Nie, Ian Lai, Gregory D. Wall, Monte M. Winslow, Dmitri A. Petrov, Ian P. Winters, Michael J. Rosen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 11.
https://doi.org/10.1158/1538-7445.AM2023-11
Published: 04 April 2023
View article titled, Abstract 11: Analysis of 30 million tumor time course reveals that inactivating tumor suppressors produces complex gene-specific, time-dependent growth dynamics
Journal Articles

Abstract 2789: Tumor suppressor genotype dramatically impacts lung cancer response to KRAS G12C inhibitors in vivo

Free
Paul J. McMurdie, Ian P. Winters, Lily M. Blair, Lafia Sebastian, Vy Tran, Gabriel Grenot, Edwin A. Apilado, Edwin A. Apilado, Ian K. Lai, Gregory D. Wall, Dmitri A. Petrov, Monte M. Winslow, Michael J. Rosen, Joseph Juan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2789.
https://doi.org/10.1158/1538-7445.AM2023-2789
Published: 04 April 2023
View article titled, Abstract 2789: Tumor suppressor genotype dramatically impacts lung cancer response to KRAS G12C inhibitors in vivo
Journal Articles

Abstract 5723: An in vivo pharmacogenomics platform replicates and extends biomarkers of therapy response identified via causal inference analysis of clinical data

Free
David Amar, Erick Scott, Ian P. Winters, Gregory D. Wall, Dmitri A. Petrov, Monte M. Winslow, Joseph Juan, Ian K. Lai, Lafia Sebastian, Edwin A. Apilado, Gabriel Grenot, Vy B. Tran, Charles Rudin, Michael J. Rosen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5723.
https://doi.org/10.1158/1538-7445.AM2023-5723
Published: 04 April 2023
View article titled, Abstract 5723: An in vivo pharmacogenomics platform replicates and extends biomarkers of therapy response identified via causal inference analysis of clinical data
Journal Articles

Quantitative In Vivo Analyses Reveal a Complex Pharmacogenomic Landscape in Lung Adenocarcinoma

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Chuan Li, Wen-Yang Lin, Hira Rizvi, Hongchen Cai, Christopher D. McFarland, Zoe N. Rogers, Maryam Yousefi, Ian P. Winters, Charles M. Rudin, Dmitri A. Petrov, Monte M. Winslow
Journal: Cancer Research
Cancer Res (2021) 81 (17): 4570–4580.
https://doi.org/10.1158/0008-5472.CAN-21-0716
Published: 01 September 2021
View article titled, Quantitative In Vivo Analyses Reveal a Complex Pharmacogenomic Landscape in Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Abstract IA26: Multiplexed functional cancer genomics

Free
Hongchen Cai, Chuan Li, Su Kit Chew, Maryam Yousefi, Giorgia Foggetti, Wen-Yang Lin, Zoë N. Rogers, Ian P. Winters, Christopher D. McFarland, Katherina Politi, Charlie Swanton, Dmitri A. Petrov, Monte M. Winslow
Journal: Cancer Research
Cancer Res (2020) 80 (11_Supplement): IA26.
https://doi.org/10.1158/1538-7445.CAMODELS2020-IA26
Published: 02 June 2020
View article titled, Abstract IA26: Multiplexed functional cancer genomics