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Journal Articles

Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine Gliomas

Cancer Res (2019) 79 (16): 4026–4041.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-3521

Published: 15 August 2019

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Journal Articles

Abstract 3014: Gene signatures identify quinolate phosphoribosyltransferase as a key mediator of acquired resistance to Panobinostat and Bortezomib in glioma, and NAD+ biosynthesis as a targetable pathway to reverse treatment resistance

Esther P. Jane, Daniel R. Premkumar, Sameer Agnihotri, Max Myers, Ansuman Chattopadhyay, D. Lansing Taylor, Mark Schurdak, Andrew Stern, Ian F. Pollack

Cancer Res (2019) 79 (13_Supplement): 3014.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3014

Published: 01 July 2019

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Journal Articles

Abstract 3940: Transformation by ENO1 highlights the positive relationship between HIF1A's and VEGFA's RNA expression levels, putatively by counteracting heterogeneity in glioblastomas

Marie E. Beckner, Ian F. Pollack, Ronald L. Hamilton

Cancer Res (2017) 77 (13_Supplement): 3940.

DOI: https://doi.org/10.1158/1538-7445.AM2017-3940

Published: 01 July 2017

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Journal Articles

Abstract 3767: Identification of a novel and a shared H3.3K27M mutation derived neoantigen epitope and H3.3K27M specific TCR engineered T cell therapy for glioma

Zinal Chheda, Gary Kohanbash, John Sidney, Kaori Okada, Naznin Jahan, Diego Carrera, Payal Watchmaker, Kira Downey, Shuming Liu, Shruti Shrivastav, Sabine Mueller, Ian F. Pollack, Angel M. Carcaboso, Alessandro Sette, Yafei Hou, Hideho Okada

Cancer Res (2017) 77 (13_Supplement): 3767.

DOI: https://doi.org/10.1158/1538-7445.AM2017-3767

Published: 01 July 2017

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Journal Articles

Abstract 5510: ABT-737 synergizes with Vorinostat to induce apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines

Kimberly A. Foster, Daniel R. Premkumar, Esther P. Jane, Alejandro Morales, Ian F. Pollack

Cancer Res (2014) 74 (19_Supplement): 5510.

DOI: https://doi.org/10.1158/1538-7445.AM2014-5510

Published: 01 October 2014

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Journal Articles

Abstract LB-131: Peptide vaccine therapy for childhood gliomas: interim results of a pilot study

Ian F. Pollack, Regina I. Jakacki, Lisa H. Butterfield, Hideho Okada

Cancer Res (2012) 72 (8_Supplement): LB-131.

DOI: https://doi.org/10.1158/1538-7445.AM2012-LB-131

Published: 15 April 2012

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Journal Articles

Abstract 5558: Interplay between BRAF, p16, p53, and MIB1 in pediatric low grade gliomas

Craig Horbinski, Marina N. Nikiforova, Jill Hagenkord, Ronald L. Hamilton, Ian F. Pollack

Cancer Res (2012) 72 (8_Supplement): 5558.

DOI: https://doi.org/10.1158/1538-7445.AM2012-5558

Published: 15 April 2012

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Journal Articles

Abstract 5150: Oncogene amplification in glioblastomas associates specifically with the increased expression of multiple glycolytic mediators

Marie E. Beckner, Jeffrey A. Kant, Ian F. Pollack, Mary L. Nordberg, Ronald L. Hamilton

Cancer Res (2012) 72 (8_Supplement): 5150.

DOI: https://doi.org/10.1158/1538-7445.AM2012-5150

Published: 15 April 2012

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Journal Articles

Abstract 1951: Inhibition of aurora kinase using VX-680 enhances the radiation response in glioma cells

Esther P. Jane, Daniel R. Premkumar, Ian F. Pollack

Cancer Res (2011) 71 (8_Supplement): 1951.

DOI: https://doi.org/10.1158/1538-7445.AM2011-1951

Published: 15 April 2011

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Journal Articles

Abstract 1932: Bortezomib sensitizes malignant human glioma cells to histone deacetylase inhibitors depends on reactive oxygen species production, mitochondrial dysfunction, Noxa upregulation and Mcl-1 cleavage

Daniel R. Premkumar, Esther P. Jane, Naomi R. Agostino, Ian F. Pollack

Cancer Res (2011) 71 (8_Supplement): 1932.

DOI: https://doi.org/10.1158/1538-7445.AM2011-1932

Published: 15 April 2011

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Journal Articles

Abstract 4754: Type-1 dendritic cell vaccines in combination with poly-ICLC-association between positive tetramer response and 6-month progression-free survival in patients with recurrent malignant glioma

Hideho Okada, Frank S. Lieberman, Aki Hoji, Pawel Kalinski, Arlan H. Mintz, Johnathan A. Engh, Deric M. Park, David L. Bartlett, Herbert Zeh, Theresa L. Whiteside, Lisa H. Butterfield, Ronald L. Hamilton, Andres M. Salazar, Ian F. Pollack

Cancer Res (2010) 70 (8_Supplement): 4754.

DOI: https://doi.org/10.1158/1538-7445.AM10-4754

Published: 15 April 2010

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Abstract 5209: Abrogation of STAT3 activation by JSI-124 enhances dasatinib-induced cytotoxicity in malignant human glioma cell lines

Esther P. Jane, Daniel R. Premkumar, Naomi R. Agostino, Joseph L. Scialabba, Ian F. Pollack

Cancer Res (2010) 70 (8_Supplement): 5209.

DOI: https://doi.org/10.1158/1538-7445.AM10-5209

Published: 15 April 2010

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Journal Articles

Identification of Interleukin-13 Receptor α2 Peptide Analogues Capable of Inducing Improved Antiglioma CTL Responses

Junichi Eguchi, Manabu Hatano, Fumihiko Nishimura, Xinmei Zhu, Jill E. Dusak, Hidemitsu Sato, Ian F. Pollack, Walter J. Storkus, Hideho Okada

Cancer Res (2006) 66 (11): 5883–5891.

DOI: https://doi.org/10.1158/0008-5472.CAN-06-0363

Published: 01 June 2006

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Journal Articles

Adaptations mediated by Akt via ATP citrate lyase and glycogen synthase kinase-3 to enhance glycolysis in astrocytoma pseudopodia

Marie E. Beckner, Naomi R. Agostino, Zhe Zhang, Billy W. Day, Ian F. Pollack

Cancer Res (2006) 66 (8_Supplement): 428.

Published: 15 April 2006

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Journal Articles

Cells from a cavitronic ultrasonic aspirator (CUSA) astrocytoma specimen formed pseudopodia and exhibited neuroectodermal features.

Marie E. Beckner, Esther P. Jane, Daniel R. Premkumar, Brian Jankowitz, Naomi R. Agostino, Kevin A. Walter, Ronald L. Hamilton, Ian F. Pollack

Cancer Res (2006) 66 (8_Supplement): 1207.

Published: 15 April 2006

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Journal Articles

Reactivity for activated epidermal growth factor receptor is demonstrated in the pseudopodia of migratory glioma cells

Marie E. Beckner, Sadie A. Aznavoorian-Cheshire, Ian F. Pollack

Cancer Res (2005) 65 (9_Supplement): 1327.

Published: 01 May 2005

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Journal Articles

Synergistic augmentation of vincristine-induced cytotoxicity by phosphatidylinositol 3-kinase inhibitor in human malignant glioma cells: Evidence for the involvement of p38 and ERK signaling pathway.

Daniel Premkumar, John Mathas, Beth Arnold, Ian F. Pollack

Cancer Res (2005) 65 (9_Supplement): 106.

Published: 01 May 2005

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Journal Articles

A myristoylated peptide derived from key phosphorylation sites on GSK-3α/β suppressed migratory glioma cells shown to be glycolytic with proteomics.

Marie E. Beckner, Fatima Burovic, Ian F. Pollack

Cancer Res (2005) 65 (9_Supplement): 70.

Published: 01 May 2005

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Journal Articles

Delivery of Interferon-α Transfected Dendritic Cells into Central Nervous System Tumors Enhances the Antitumor Efficacy of Peripheral Peptide-Based Vaccines

Hideho Okada, Takahiko Tsugawa, Hidemitsu Sato, Naruo Kuwashima, Andrea Gambotto, Kaori Okada, Jill E. Dusak, Wendy K. Fellows-Mayle, Glenn D. Papworth, Simon C. Watkins, William H. Chambers, Douglas M. Potter, Walter J. Storkus, Ian F. Pollack

Cancer Res (2004) 64 (16): 5830–5838.

DOI: https://doi.org/10.1158/0008-5472.CAN-04-0130

Published: 16 August 2004

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Journal Articles

Co-amplification of TIIα and Her-2/neu in pediatric malignant non-brainstem gliomas.

Claudia Bredel, Silke Lassmann, Ian F. Pollack, Rolf Knoth, Ronald L. Hamilton, Irene Slavc, Benedikt Volk, Martin Werner, Josef Zentner, Markus Bredel

Cancer Res (2004) 64 (7_Supplement): 718.

Published: 01 April 2004

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NARROW

Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine Gliomas

Abstract 3014: Gene signatures identify quinolate phosphoribosyltransferase as a key mediator of acquired resistance to Panobinostat and Bortezomib in glioma, and NAD+ biosynthesis as a targetable pathway to reverse treatment resistance

Abstract 3940: Transformation by ENO1 highlights the positive relationship between HIF1A's and VEGFA's RNA expression levels, putatively by counteracting heterogeneity in glioblastomas

Abstract 3767: Identification of a novel and a shared H3.3K27M mutation derived neoantigen epitope and H3.3K27M specific TCR engineered T cell therapy for glioma

Abstract 5510: ABT-737 synergizes with Vorinostat to induce apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines

Abstract LB-131: Peptide vaccine therapy for childhood gliomas: interim results of a pilot study

Abstract 5558: Interplay between BRAF, p16, p53, and MIB1 in pediatric low grade gliomas

Abstract 5150: Oncogene amplification in glioblastomas associates specifically with the increased expression of multiple glycolytic mediators

Abstract 1951: Inhibition of aurora kinase using VX-680 enhances the radiation response in glioma cells

Abstract 1932: Bortezomib sensitizes malignant human glioma cells to histone deacetylase inhibitors depends on reactive oxygen species production, mitochondrial dysfunction, Noxa upregulation and Mcl-1 cleavage

Abstract 4754: Type-1 dendritic cell vaccines in combination with poly-ICLC-association between positive tetramer response and 6-month progression-free survival in patients with recurrent malignant glioma

Abstract 5209: Abrogation of STAT3 activation by JSI-124 enhances dasatinib-induced cytotoxicity in malignant human glioma cell lines

Identification of Interleukin-13 Receptor α2 Peptide Analogues Capable of Inducing Improved Antiglioma CTL Responses

Adaptations mediated by Akt via ATP citrate lyase and glycogen synthase kinase-3 to enhance glycolysis in astrocytoma pseudopodia

Cells from a cavitronic ultrasonic aspirator (CUSA) astrocytoma specimen formed pseudopodia and exhibited neuroectodermal features.

Reactivity for activated epidermal growth factor receptor is demonstrated in the pseudopodia of migratory glioma cells

Synergistic augmentation of vincristine-induced cytotoxicity by phosphatidylinositol 3-kinase inhibitor in human malignant glioma cells: Evidence for the involvement of p38 and ERK signaling pathway.

A myristoylated peptide derived from key phosphorylation sites on GSK-3α/β suppressed migratory glioma cells shown to be glycolytic with proteomics.

Delivery of Interferon-α Transfected Dendritic Cells into Central Nervous System Tumors Enhances the Antitumor Efficacy of Peripheral Peptide-Based Vaccines

Co-amplification of TIIα and Her-2/neu in pediatric malignant non-brainstem gliomas.

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