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Journal Articles

Abstract 3240: Analytical validation of CancerDetect™ RUO assay: a minimal residual disease detection test that integrates tumor-informed and tumor-agnostic approaches with large-scale mutation monitoring

Free
Sunghoon Heo, Seon-Kyu Ham, Hayoon Lee, Hwang-Phill Kim, Duhee Bang, Sang-Hyun Song, Tae-You Kim
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3240.
https://doi.org/10.1158/1538-7445.AM2025-3240
Published: 21 April 2025
View article titled, Abstract 3240: Analytical validation of CancerDetect™ RUO assay: a minimal residual disease detection test that integrates tumor-informed and tumor-agnostic approaches with large-scale mutation monitoring
Journal Articles

Abstract 41: Generation and multiomic profiling of aAPC/TP53double knockout normal colon organoid

Free
Younghee Choi, Eunju Kim, Jihyun Park, Sang-Hyun Song, Tae-You Kim
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 41.
https://doi.org/10.1158/1538-7445.AM2025-41
Published: 21 April 2025
View article titled, Abstract 41: Generation and multiomic profiling of aAPC/TP53double knockout normal colon organoid
Journal Articles

Abstract 4572: Preliminary results of perioperative minimal residual disease monitoring using a tumor-informed ctDNA assay in stage II-III breast cancer

Free
Jongseong Ahn, Jiwoong Jung, Yongjun Cha, Sunghoon Heo, Eunhye Kang, Woosung Chung, Hwang-Phill Kim, Duhee Bang, Sang-Hyun Song, Han-Byeol Lee, Wonshik Han, Tae-You Kim
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4572.
https://doi.org/10.1158/1538-7445.AM2025-4572
Published: 21 April 2025
View article titled, Abstract 4572: Preliminary results of perioperative minimal residual disease monitoring using a tumor-informed ctDNA assay in stage II-III breast cancer
Journal Articles

Abstract 4556: Postoperative minimal residual disease detection using tumor-informed circulating tumor DNA analysis in stage II-III gastric cancer

Free
Bom Han, Hayoon Lee, Minkyu Jung, Bum Jun Kim, Yongjun Cha, Sunghoon Heo, Sun Young Rha, Hyung-Don Kim, Min-Hee Ryu, Dong-Hoe Koo, Jong Gwang Kim, Hye Sook Han, Sun Jin Sym, Jae-Joon Kim, Do-Youn Oh, Keun-Wook Lee, Hwang-Phill Kim, Duhee Bang, Sang-Hyun Song, Tae-You Kim, Dae Young Zang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4556.
https://doi.org/10.1158/1538-7445.AM2025-4556
Published: 21 April 2025
View article titled, Abstract 4556: Postoperative minimal residual disease detection using tumor-informed circulating tumor DNA analysis in stage II-III gastric cancer
Journal Articles

Abstract 3260: Perioperative tumor-informed ctDNA monitoring for minimal residual disease in triple-negative and HER2-positive breast cancer patients

Free
Yongjun Cha, Junghoon Shin, Jongseong Ahn, Sunghoon Heo, Hwang-Phill Kim, Duhee Bang, Sang-Hyun Song, Young-Hyuck Im, Ji-Yeon Kim, Tae-You Kim
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3260.
https://doi.org/10.1158/1538-7445.AM2025-3260
Published: 21 April 2025
View article titled, Abstract 3260: Perioperative tumor-informed ctDNA monitoring for minimal residual disease in triple-negative and HER2-positive breast cancer patients
Journal Articles

Abstract 6988: TP53RK regulates DNA replication by CDC7-mediated MCM helicase phosphorylation in colorectal cancer

Free
Younghee Choi, Ji-won Park, Jun-kyu Kang, Eun-ju Kim, Sang-Hyun Song, Eugene C. Yi, Tae-You Kim
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6988.
https://doi.org/10.1158/1538-7445.AM2024-6988
Published: 22 March 2024
View article titled, Abstract 6988: TP53RK regulates DNA replication by CDC7-mediated MCM helicase phosphorylation in colorectal cancer
Journal Articles

Abstract 1696: ACTL6A deficiency drives cell death through KLF4-involved chromatin accessibility changes in colorectal cancer

Free
Hye-Ju Yang, Eun-Ju Kim, Sang-Hyun Song, Tae-You Kim
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1696.
https://doi.org/10.1158/1538-7445.AM2024-1696
Published: 22 March 2024
View article titled, Abstract 1696: ACTL6A deficiency drives cell death through KLF4-involved chromatin accessibility changes in colorectal cancer
Journal Articles

Abstract 4784: Multiomic landscape of evolution of Warburg effect identifies drivers of breast cancer

Free
Rafael Renatino Canevarolo, Praneeth Reddy Sudalagunta, Joon-Hyun Song, Erez Persi, Mehdi Damaghi, Ariosto Siqueira Silva
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4784.
https://doi.org/10.1158/1538-7445.AM2023-4784
Published: 04 April 2023
View article titled, Abstract 4784: Multiomic landscape of evolution of Warburg effect identifies drivers of breast cancer
Journal Articles

Abstract 870: Glutamine metabolism drives some mechanisms of PARP inhibitor persistence in ovarian cancer

Free
Adriana Del Pino Herrera, Meghan Ferrall-Fairbanks, Mehdi Damaghi, Joon-Hyun Song, Snigdha Kanadibhotla
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 870.
https://doi.org/10.1158/1538-7445.AM2023-870
Published: 04 April 2023
View article titled, Abstract 870: Glutamine metabolism drives some mechanisms of PARP inhibitor persistence in ovarian cancer
Journal Articles

Abstract 4313: A novel gene regulatory network model identifies master regulators in cancer

Free
Praneeth Reddy Sudalagunta, Rafael Renatino Canevarolo, Mark Meads, Maria Coelho Silva, Xiaohong Zhao, Raghunandan Reddy Alugubelli, Joon-hyun Song, Erez Persi, Mehdi Damaghi, Kenneth H. Shain, Ariosto Silva
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4313.
https://doi.org/10.1158/1538-7445.AM2023-4313
Published: 04 April 2023
View article titled, Abstract 4313: A novel gene regulatory network model identifies master regulators in cancer
Journal Articles

Abstract 36: Application of patients derived organoids as co-clinical model

Free
Young-Won Cho, Hwang-Phill Kim, Dong Wook Min, Yoojoo Lim, Sang-Hyun Song, Sae-Won Han, Tae-You Kim
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 36.
https://doi.org/10.1158/1538-7445.AM2019-36
Published: 01 July 2019
View article titled, Abstract 36: Application of patients derived organoids as co-clinical model
Journal Articles

Abstract 419: Single cell-driven secreted proteins as a surrogate biomarker for Cetuximab therapy in colorectal cancer

Free
Ye-Lim Park, Hwang-Phill Kim, Jun Kyu Kang, Yoo Joo Lim, Sang-Hyun Song, Sae-Won Han, Tae-You Kim
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 419.
https://doi.org/10.1158/1538-7445.AM2019-419
Published: 01 July 2019
View article titled, Abstract 419: Single cell-driven secreted proteins as a surrogate biomarker for Cetuximab therapy in colorectal cancer
Journal Articles

Abstract 1175: The establishment of single colorectal cancer organoid clones derived from regional biopsies for studying tumor heterogeneity

Free
Myoung-Hyun Song, Ja-Lok Ku
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1175.
https://doi.org/10.1158/1538-7445.AM2018-1175
Published: 01 July 2018
View article titled, Abstract 1175: The establishment of single colorectal cancer organoid clones derived from regional biopsies for studying tumor heterogeneity
Journal Articles

Abstract 5214: Activation of WNT/b-catenin signaling results in resistance to PI3K/mTOR dual inhibitor in co-existing KRAS and PIK3CA mutant colorectal cancer cells

Free
Ye-Lim Park, Hwang-Phill Kim, Seul-Ki Cheon, Jun-Kyu Kang, Yoojoo Lim, Sang-Hyun Song, Sae-Won Han, Tae-you Kim
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5214.
https://doi.org/10.1158/1538-7445.AM2017-5214
Published: 01 July 2017
View article titled, Abstract 5214: Activation of WNT/b-catenin signaling results in resistance to PI3K/mTOR dual inhibitor in co-existing KRAS and PIK3CA mutant colorectal cancer cells
Journal Articles

Abstract 3141: Combined cetuximab and pemetrexed therapy enhances cytotoxicity against crizotinib-resistant non-small cell lung cancer cells by downregulating thymidylate synthase

Free
Hwang-Phill Kim, Sae-Won Han, Sang-Hyun Song, Tae-You Kim
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3141.
https://doi.org/10.1158/1538-7445.AM2017-3141
Published: 01 July 2017
View article titled, Abstract 3141: Combined cetuximab and pemetrexed therapy enhances cytotoxicity against crizotinib-resistant non-small cell lung cancer cells by downregulating thymidylate synthase
Journal Articles

Abstract 3167: MIF-induced stat3 activation promotes resistance to MEK blockade in KRAS mutant colorectal cancer cells

Free
Seul-Ki Cheon, Hwang-Phill Kim, Ye-Lim Park, Si Hyun Lee, Jun-Kyu Kang, Yoojoo Lim, Sang-Hyun Song, Sae-Won Han, Tae-You Kim
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3167.
https://doi.org/10.1158/1538-7445.AM2017-3167
Published: 01 July 2017
View article titled, Abstract 3167: MIF-induced stat3 activation promotes resistance to MEK blockade in KRAS mutant colorectal cancer cells
Journal Articles

Abstract 3599: Resistance mechanisms to HER2-targeting treatment in HER2-positive gastric cancer

Free
Kyo Hwa Kang, Ah-Rong Nam, Ji Eun Park, Ju-Hee Bang, Jin Ling, Mei Hua Jin, Tae Yong Kim, Sae-Won Han, Sang-Hyun Song, Seock-Ah Im, Tae-You Kim, Do-Youn Oh, Yung-Jue Bang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3599.
https://doi.org/10.1158/1538-7445.AM2015-3599
Published: 01 August 2015
View article titled, Abstract 3599: Resistance mechanisms to HER2-targeting treatment in HER2-positive gastric cancer
Journal Articles

Abstract 1714: The role and mechanism of JAB1 as a therapeutic target in biliary tract cancer

Free
Ah-Rong Nam, Kyo Hwa Kang, Ji Eun Park, Ju-Hee Bang, Ling Jin, Mei Hua Jin, Tae Yong Kim, Sae-Won Han, Sang-Hyun Song, Seock-Ah Im, Tae-You Kim, Do-Youn Oh, Yung-Jue Bang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1714.
https://doi.org/10.1158/1538-7445.AM2015-1714
Published: 01 August 2015
View article titled, Abstract 1714: The role and mechanism of JAB1 as a therapeutic target in biliary tract cancer
Journal Articles

Abstract 5484: FGFR2 amplification is predictive of sensitivity to regorafenib in gastric and colorectal cancers

Free
Yongjun Cha, Hwang-Phill Kim, Sae-won Han, Jiyeon Yun, Sang-Hyun Song, Tae-You Kim
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5484.
https://doi.org/10.1158/1538-7445.AM2015-5484
Published: 01 August 2015
View article titled, Abstract 5484: FGFR2 amplification is predictive of sensitivity to regorafenib in gastric and colorectal cancers
Journal Articles

Abstract 747: Evaluation of Src as a therapeutic target and development of biomarkers of Src inhibitor in cancer

Free
Ah-Rong Nam, Hyun-Jin Nam, Kyo Hwa Kang, Ji Eun Park, Tae Yong Kim, Sae-Won Han, Sang-Hyun Song, Seock-Ah Im, Tae-You Kim, Do-Youn Oh, Yung-Jue Bang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 747.
https://doi.org/10.1158/1538-7445.AM2014-747
Published: 01 October 2014
View article titled, Abstract 747: Evaluation of Src as a therapeutic target and development of biomarkers of Src inhibitor in cancer