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Hyun Cheol Chung
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Journal Articles

Abstract 4915: Identification and validation of novel prognostic genetic markers in HER2-negative advanced gastric cancer (AGC) by artificial intelligence (AI) deep learning and machine learning algorithm

Free
Sejung Park, Seok-Jae Heo, Choong-Kun Lee, Yaeji Lee, Woo Sun Kwon, Jingmin Che, Minseok Kim, Hyun Cheol Chung, Sun Young Rha
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4915.
https://doi.org/10.1158/1538-7445.AM2024-4915
Published: 22 March 2024
View articletitled, Abstract 4915: Identification and validation of novel prognostic genetic markers in HER2-negative advanced gastric cancer (AGC) by artificial intelligence (AI) deep learning and machine learning algorithm
Journal Articles

Abstract 229: Molecular-genomic characterization of metastatic gastric cancer organoids and establishment of organoid-immune cell co-culture model

Free
Han Byeol Mun, juin Park, Jinsoo Jang, Jingmin Che, Tae Soo Kim, Woo Sun Kwon, Hyun Cheol Chung, Sun Young Rha
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 229.
https://doi.org/10.1158/1538-7445.AM2024-229
Published: 22 March 2024
View articletitled, Abstract 229: Molecular-genomic characterization of metastatic gastric cancer organoids and establishment of organoid-immune cell co-culture model
Journal Articles

Abstract 1567: Anti-cancer effect of Mps1 inhibitor in gastric cancer

Free
Kim Eun Seo, Woo Sun Kwon, Kim Tae Soo, Juin Park, Sang Woo Cho, Sunghwan Kim, Hyun Cheol Chung, Sun Young Rha
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1567.
https://doi.org/10.1158/1538-7445.AM2023-1567
Published: 04 April 2023
View articletitled, Abstract 1567: Anti-cancer effect of Mps1 inhibitor in gastric cancer
Journal Articles

Abstract 4604: Effect of CDK 4/6 inhibition on anti-angiogenesis effect in gastric cancer

Free
Sang Woo Cho, Woo Sun Kwon, Tae Soo Kim, Juin Park, Eun Seo Kim, Hyun Cheol Chung, Sun Young Rha
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4604.
https://doi.org/10.1158/1538-7445.AM2023-4604
Published: 04 April 2023
View articletitled, Abstract 4604: Effect of CDK 4/6 inhibition on anti-angiogenesis effect in gastric cancer
Journal Articles

Abstract 2685: Synergistic antitumor effect of oncolytic virus and cytotoxic chemotherapy in gastric cancer

Free
Jee Hung Kim, YeLin Kim, Youkeun Shin, Dagyo Oh, Woo Sun Kwon, Tae Soo Kim, Namhee Lee, Keunhee Oh, Hyun Cheol Chung, Hei-Cheul Jeung, Sun Young Rha
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2685.
https://doi.org/10.1158/1538-7445.AM2023-2685
Published: 04 April 2023
View articletitled, Abstract 2685: Synergistic antitumor effect of oncolytic virus and cytotoxic chemotherapy in gastric cancer
Journal Articles

Abstract 1399: Genomic profiling of gastric cancer with peritoneal metastasis identifies molecular subtypes and a potential molecular-guided therapeutic strategy for intractable gastric cancer

Free
Juin Park, Woo Sun Kwon, Jingmin Che, Tae Soo Kim, Sang Woo Cho, Eun Seo Kim, Hyun Cheol Chung, Sun Young Rha
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1399.
https://doi.org/10.1158/1538-7445.AM2023-1399
Published: 04 April 2023
View articletitled, Abstract 1399: Genomic profiling of gastric cancer with peritoneal metastasis identifies molecular subtypes and a potential molecular-guided therapeutic strategy for intractable gastric cancer
Journal Articles

Abstract 5700: Increasing efficacy of iBET-151, a small molecule inhibitor of BET protein in combination with paclitaxel in gastric cancer

Free
Sun Kyoung Kang, Sang Woo Cho, Woo Sun Kwon, Tae Soo Kim, Hyun Cheol Chung, Sun Young Rha
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5700.
https://doi.org/10.1158/1538-7445.AM2022-5700
Published: 15 June 2022
View articletitled, Abstract 5700: Increasing efficacy of iBET-151, a small molecule inhibitor of BET protein in combination with paclitaxel in gastric cancer
Journal Articles

Abstract 5445: New discovery and development of transglutaminase 2 inhibitor

Free
Eun Yi Cho, Hyeon Joo Kim, Byeonghak Moon, Yerin Jo, Jinsu Bae, Ga Ram Kim, Yong-Chul Kim, Sun Kyoung Kang, Woo Sun Kwon, Tae Soo Kim, Sun Young Rha, Hyun Cheol Chung
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5445.
https://doi.org/10.1158/1538-7445.AM2022-5445
Published: 15 June 2022
View articletitled, Abstract 5445: New discovery and development of transglutaminase 2 inhibitor
Journal Articles

Abstract 5079: Comparative proteome analysis for predicting the prognosis of trastuzumab-based therapy

Free
Juin Park, Woo Sun Kwon, Sun Kyoung Kang, Tae Soo Kim, Jihyun Hwang, Sang Woo Cho, Kyunggon Kim, Hyun Cheol Chung, Sun Young Rha
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5079.
https://doi.org/10.1158/1538-7445.AM2022-5079
Published: 15 June 2022
View articletitled, Abstract 5079: Comparative proteome analysis for predicting the prognosis of trastuzumab-based therapy
Journal Articles

Abstract 5761: Validation of TMB (tumor mutational burden) quantification using putative driver mutations in customized targeted sequencing platform

Free
Woo Sun Kwon, Jingmin Che, Sun Young Rha, Hyun Cheol Chung
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5761.
https://doi.org/10.1158/1538-7445.AM2022-5761
Published: 15 June 2022
View articletitled, Abstract 5761: Validation of TMB (tumor mutational burden) quantification using putative driver mutations in customized targeted sequencing platform
Journal Articles

Abstract 1090: Overcoming trastuzumab resistance using trastuzumab deruxtecan (T-DXd), a HER2 targeting antibody drug conjugate, in HER2 amplified gastric cancer

Free
Juin Park, Inhye Jeong, Sun Kyoung Kang, Seo Young Yu, Woo Sun Kwon, Tae Soo Kim, Jihyun Hwang, Hyun Cheol Chung, Sun Young Rha
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1090.
https://doi.org/10.1158/1538-7445.AM2021-1090
Published: 01 July 2021
View articletitled, Abstract 1090: Overcoming trastuzumab resistance using trastuzumab deruxtecan (T-DXd), a HER2 targeting antibody drug conjugate, in HER2 amplified gastric cancer
Journal Articles

Abstract 945: Trastuzumab deruxtecan (T-DXd) sensitivity in various levels of HER2 expressing gastric cancer cells

Free
Seo Young Yu, Juin Park, Woo Sun Kwon, Inhye Jeong, Sun Kyoung Kang, Hyun Joo Bae, Tae Soo Kim, Hyun Cheol Chung, Sun Young Rha
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 945.
https://doi.org/10.1158/1538-7445.AM2021-945
Published: 01 July 2021
View articletitled, Abstract 945: Trastuzumab deruxtecan (T-DXd) sensitivity in various levels of HER2 expressing gastric cancer cells
Journal Articles

Abstract CT151: Phase 2 study of TAS-117 in advanced solid tumors harboringphosphatidylinositol 3-kinase/v-akt murine thymoma viral oncogene homolog gene aberrations

Free
Jii Bum Lee, Minkyu Jung, Seung Hoon Beom, Gun Min Kim, Hye Ryun Kim, Joo Hyuk Sohn, Joong Bae Ahn, Sun Young Rha, Hyun Cheol Chung
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT151.
https://doi.org/10.1158/1538-7445.AM2021-CT151
Published: 01 July 2021
View articletitled, Abstract CT151: Phase 2 study of TAS-117 in advanced solid tumors harboringphosphatidylinositol 3-kinase/v-akt murine thymoma viral oncogene homolog gene aberrations
Journal Articles

Abstract CT159: Open label, single-arm, multi-center phase Ib/II study to evaluate the safety and efficacy of nivolumab in combination with paclitaxel in Epstein-Barr virus (EBV)-related, or microsatellite instability-high (MSI-H), or programmed cell death ligand 1 (PD-L1) positive advanced gastric cancer (AGC)

Free
Rha Sun Young, Jii Bum Lee, Hyo Song Kim, Minkyu Jung, Choong-kun Lee, Sook Ryun Park, Dong-Hoe Koo, Hyun Woo Lee, Woo Kyun Bae, Hei Cheul Jeung, Hyun Cheol Chung
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT159.
https://doi.org/10.1158/1538-7445.AM2021-CT159
Published: 01 July 2021
View articletitled, Abstract CT159: Open label, single-arm, multi-center phase Ib/II study to evaluate the safety and efficacy of nivolumab in combination with paclitaxel in Epstein-Barr virus (EBV)-related, or microsatellite instability-high (MSI-H), or programmed cell death ligand 1 (PD-L1) positive advanced gastric cancer (AGC)
Journal Articles

Abstract 2973: Establishment of organoids and patient derived cancer cell lines from gastric cancer body fluids as preclinical models for personalized therapy

Free
Sun Kyoung Kang, Hyun Joo Bae, Woo Sun Kwon, Tae Soo Kim, Sujin Lee, Sang Woo Cho, Hyun Cheol Chung, Sun Young Rha
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2973.
https://doi.org/10.1158/1538-7445.AM2021-2973
Published: 01 July 2021
View articletitled, Abstract 2973: Establishment of organoids and patient derived cancer cell lines from gastric cancer body fluids as preclinical models for personalized therapy
Journal Articles

Abstract 2055: Evaluation of DNA damage repair gene alterations, microsatellite instability status, and tumor mutational burden as predictive biomarkers of olaparib sensitivity in gastric cancer

Free
Jihyun Hwang, Woo sun Kwon, Juin Park, Hyun Joo Bae, Inhye Jeong, Sun Kyoung Kang, Tae Soo Kim, Jingmin Che, Hyun Cheol Chung, Sun Young Rha
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2055.
https://doi.org/10.1158/1538-7445.AM2021-2055
Published: 01 July 2021
View articletitled, Abstract 2055: Evaluation of DNA damage repair gene alterations, microsatellite instability status, and tumor mutational burden as predictive biomarkers of olaparib sensitivity in gastric cancer
Journal Articles

Abstract PS12-07: Lenvatinib plus pembrolizumab for previously treated, advanced triple-negative breast cancer: Early results from the multicohort phase 2 LEAP-005 study

Free
Hyun Cheol Chung, Esma Saada-Bouzid, Federico Longo Muñoz, Eduardo Yanez, Seock-Ah Im, Eduardo Castanon, Donna M. Graham, Javier Garcia-Corbacho, Juanita Lopez, Razi Ghori, Corina Dutcus, Alan Smith, Kevin Norwood, Carlos Gomez-Roca
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS12-07.
https://doi.org/10.1158/1538-7445.SABCS20-PS12-07
Published: 15 February 2021
View articletitled, Abstract PS12-07: Lenvatinib plus pembrolizumab for previously treated, advanced triple-negative breast cancer: Early results from the multicohort phase 2 LEAP-005 study
Journal Articles

Abstract P3-08-43: Comprehensive analysis of lymphopenia in large-scaled early and metastatic breast cancer database cohort

Free
Jee Hung Kim, Min Hwan Kim, Gun Min Kim, Byeong-Woo Park, Young Up Cho, Seung Il Kim, Seho Park, Hyung Seok Park, Ji Ye Kim, Hyun Cheol Chung, Soonmyung Paik, Joohyuk Sohn
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-08-43.
https://doi.org/10.1158/1538-7445.SABCS19-P3-08-43
Published: 15 February 2020
View articletitled, Abstract P3-08-43: Comprehensive analysis of lymphopenia in large-scaled early and metastatic breast cancer database cohort
Journal Articles

Abstract CT073: Pembrolizumab after two or more lines of prior therapy in patients with advanced small-cell lung cancer (SCLC): Results from the KEYNOTE-028 and KEYNOTE-158 studies

Free
Hyun Cheol Chung, Sarina A. Piha-Paul, Jose Lopez-Martin, Jan H.M. Schellens, Steven Kao, Wilson H. Miller, Jr., Jean-Pierre Delord, Bo Gao, David Planchard, Maya Gottfried, Alona Zer, Shadia I. Jalal, Nicolas Penel, Janice M. Mehnert, Ignacio Matos, Jaafar Bennouna, Dong-Wan Kim, Lei Xu, Suba Krishnan, Kevin Norwood, Patrick A. Ott
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT073.
https://doi.org/10.1158/1538-7445.AM2019-CT073
Published: 01 July 2019
View articletitled, Abstract CT073: Pembrolizumab after two or more lines of prior therapy in patients with advanced small-cell lung cancer (SCLC): Results from the KEYNOTE-028 and KEYNOTE-158 studies
Journal Articles

Abstract CT229: Olaparib in patients (pts) with previously treated, homologous recombination repair mutation (HRRm) or homologous recombination deficiency (HRD)-positive advanced cancer: Phase II LYNK-002 study

Free
David Hyman, Andrew Hendifar, Hyun Cheol Chung, Michele Maio, Alexandra Leary, Iben Spanggaard, Joon Rhee, Matt Marton, Menghui Chen, Suba Krishnan, Ronnie Shapira
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT229.
https://doi.org/10.1158/1538-7445.AM2019-CT229
Published: 01 July 2019
View articletitled, Abstract CT229: Olaparib in patients (pts) with previously treated, homologous recombination repair mutation (HRRm) or homologous recombination deficiency (HRD)-positive advanced cancer: Phase II LYNK-002 study