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Abstract 2223: Understanding the pro- and anti-tumorigenic microenvironments in syngeneic mice

Fulya Alkan, Raziye Piranlioglu, Eunmi Lee, Maria Ouzounova, Catherine C Hedrick, Huidong Shi, Hasan Korkaya

Cancer Res (2022) 82 (12_Supplement): 2223.

DOI: https://doi.org/10.1158/1538-7445.AM2022-2223

Published: 15 June 2022

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Journal Articles

Autocrine IL6-Mediated Activation of the STAT3–DNMT Axis Silences the TNFα–RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells

Alyssa D. Smith, Chunwan Lu, Daniela Payne, Amy V. Paschall, John D. Klement, Priscilla S. Redd, Mohammed L. Ibrahim, Dafeng Yang, Qimei Han, Zhuoqi Liu, Huidong Shi, Thomas J. Hartney, Asha Nayak-Kapoor, Kebin Liu

Cancer Res (2020) 80 (15): 3145–3156.

DOI: https://doi.org/10.1158/0008-5472.CAN-19-3670

Published: 04 August 2020

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Includes: Supplementary data

Journal Articles

Abstract 4493: SF3B1 mutation promotes c-Myc protein stability through aberrant splicing and downregulation of PP2A B56α subunit in chronic lymphocytic leukemia

Qimei Han, Libin Deng, Shuo Tu, Lirong Pei, Jeong-Hyeon Choi, Victor Jin, Huidong Shi

Cancer Res (2019) 79 (13_Supplement): 4493.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4493

Published: 01 July 2019

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Journal Articles

Abstract 5230: Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia

Qimei Han, Jianbo Wang, Austin Y. Shull, Fang Shi, Libin Deng, Jeong-Hyeon Choi, Eun-Jeong Park, Shuo Tu, Lirong Pei, Farrukh T. Awan, Roni Bollag, Locke J. Bryan, Hong-bo Xin, Chandraiah Lagisetti, Thomas R. Webb, Victor Jin, Huidong Shi

Cancer Res (2019) 79 (13_Supplement): 5230.

DOI: https://doi.org/10.1158/1538-7445.AM2019-5230

Published: 01 July 2019

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Journal Articles

Abstract LB-282: Dynamic regulation of CD73 expression in cancer associated fibroblasts enforces immunosuppression via a feedforward adenosinergic pathway

Miao Yu, Gang Guo, Lei Huang, Libin Deng, Roni Bollag, Andrew Mellor, Huidong Shi, Yan Cui

Cancer Res (2018) 78 (13_Supplement): LB-282.

DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-282

Published: 01 July 2018

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Journal Articles

Abstract 1997: Inhibition of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia

Qimei Han, Austin Young Shull, Fang Shi, Chandraiah Lagisetti, Thomas Webb, Justin Choi, Huidong Shi

Cancer Res (2016) 76 (14_Supplement): 1997.

DOI: https://doi.org/10.1158/1538-7445.AM2016-1997

Published: 15 July 2016

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Journal Articles

Abstract 4697: The covalent CDK7 inhibitor THZ1 can counteract apoptotic resistance and suppress the transcription of genes attributed to chronic lymphocytic leukemia malignancy

Austin Young Shull, Jeong-Hyeon Choi, Jordan Bauer, Lirong Pei, Farrukh T. Awan, Huidong Shi

Cancer Res (2016) 76 (14_Supplement): 4697.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4697

Published: 15 July 2016

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Journal Articles

Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth

Rajneesh Pathania, Sabarish Ramachandran, Gurusamy Mariappan, Priyanka Thakur, Huidong Shi, Jeong-Hyeon Choi, Santhakumar Manicassamy, Ravindra Kolhe, Puttur D. Prasad, Suash Sharma, Bal L. Lokeshwar, Vadivel Ganapathy, Muthusamy Thangaraju

Cancer Res (2016) 76 (11): 3224–3235.

DOI: https://doi.org/10.1158/0008-5472.CAN-15-2249

Published: 31 May 2016

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Includes: Supplementary data

Journal Articles

Abstract 2191: Transcriptome analysis demonstrates the ability of the bromodomain inhibitor JQ1 to attenuate expression of common oncogenes heterogeneously expressed among chronic lymphocytic leukemia subsets

Austin Y. Shull, Jeong-Hyeon Choi, Brian Buckley, Lirong Pei, Farrukh T. Awan, Huidong Shi

Cancer Res (2015) 75 (15_Supplement): 2191.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2191

Published: 01 August 2015

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Journal Articles

Abstract 4060: Promoter methylation regulates interferon-γ induced indoleamine 2,3-dioxygenase expression in breast cancer

Satish Kumar Reddy Noonepalle, Eun Joon Lee, Maria Ouzounova, Jaejik Kim, Jeong-Hyeon Choi, Austin Shull, Lirong Pei, Ravindra Kolhe, Pei-Yin Hsu, Nagireddy Putluri, Tim Hui-Ming Huang, Arun Sreekumar, Hasan Korkaya, David Munn, Huidong Shi

Cancer Res (2015) 75 (15_Supplement): 4060.

DOI: https://doi.org/10.1158/1538-7445.AM2015-4060

Published: 01 August 2015

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Journal Articles

Abstract 1984: SOCS3 regulates IDO proteasomal degradation and inflammatory signaling in triple negative breast cancer

Maria Ouzounova, EunMi Lee, Ena Novakovic, Satish Kumar Noonepalle, Raziye Piranlioglu, Huidong Shi, Max Wicha, Hasan Korkaya

Cancer Res (2015) 75 (15_Supplement): 1984.

DOI: https://doi.org/10.1158/1538-7445.AM2015-1984

Published: 01 August 2015

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Journal Articles

Abstract 1379: Identification of global DNA methylation signatures in glioblastoma-derived cancer stem cells

Eun Joon Lee, Prakash Rath, Jimei Liu, Dungsheng Ryu, Alan Free, Lirong Pei, Douglas C Anthony, Suash Sharma, Mark D Kirk, John J. Laterra, Duck Hwan Ryu, Jeong-Hyeon Choi, Huidong Shi, Douglas C. Miller, N. Scott Litofsky, Qi Feng

Cancer Res (2014) 74 (19_Supplement): 1379.

DOI: https://doi.org/10.1158/1538-7445.AM2014-1379

Published: 01 October 2014

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Journal Articles

Abstract 405: Mbd3 localizes at promoters, gene bodies and enhancers of active genes

Takashi Shimbo, Ying Du, Sara A. Grimm, Archana Dhasarathy, Deepak Mav, Ruchir R. Shah, Huidong Shi, Paul A. Wade

Cancer Res (2014) 74 (19_Supplement): 405.

DOI: https://doi.org/10.1158/1538-7445.AM2014-405

Published: 01 October 2014

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Journal Articles

Abstract 4012: Large-scale characterization of DNA methylation changes in human gastric carcinomas with and without metastasis

Zhaojun Liu, Jun Zhang, Yanhong Gao, Lirong Pei, Naoko Hattori, Budong Zhu, Jiafu Ji, Yasuhito Yuasa, Wooho Kim, Toshikazu Ushijima, Huidong Shi, Dajun Deng

Cancer Res (2014) 74 (19_Supplement): 4012.

DOI: https://doi.org/10.1158/1538-7445.AM2014-4012

Published: 01 October 2014

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Journal Articles

Abstract 5182: Identifying differential gene expression and splicing events in chronic lymphocytic leukemia patients through whole transcriptome profiling

Austin Y. Shull, Junfeng Luo, Jeong-Hyeon Choi, Lirong Pei, Farrukh T. Awan, Eun-Joon Lee, Jimei Liu, Phillip J. Buckhaults, Xiao-Jie Yan, Nicholas Chiorazzi, Huidong Shi

Cancer Res (2014) 74 (19_Supplement): 5182.

DOI: https://doi.org/10.1158/1538-7445.AM2014-5182

Published: 01 October 2014

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Journal Articles

Abstract 5180: Profiling signaling pathways in chronic lymphocytic leukemia using reverse phase protein array

Satish Kumar R. Noonepalle, Austin Shull, Farrukh T. Awan, Leah Pei, Zhiyong Ding, Huidong Shi

Cancer Res (2014) 74 (19_Supplement): 5180.

DOI: https://doi.org/10.1158/1538-7445.AM2014-5180

Published: 01 October 2014

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Journal Articles

Abstract B63: MBD3 accumulates at promoters and enhancers of active genes

Takashi Shimbo, Ying Du, Sara Grimm, Archana Dhasarathy, Deepak Mav, Ruchir Shah, Huidong Shi, Paul A. Wade

Cancer Res (2013) 73 (13_Supplement): B63.

DOI: https://doi.org/10.1158/1538-7445.CEC13-B63

Published: 13 May 2014

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Journal Articles

Metabolomic Profiling Reveals Potential Markers and Bioprocesses Altered in Bladder Cancer Progression

Cancer Res (2011) 71 (24): 7376–7386.

DOI: https://doi.org/10.1158/0008-5472.CAN-11-1154

Published: 15 December 2011

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Includes: Supplementary data

Journal Articles

Abstract 3003: Targeted bisulfite sequencing of CpG island DNA by solution hybrid selection and next-generation sequencing

Eun Joon Lee, Lirong Pei, Gyan Srivastava, Garima Kushwaha, Joshi Trupti, Jeong-Hyeon Choi, Xinguo Wang, Dong Xu, Kun Zhang, Huidong Shi

Cancer Res (2011) 71 (8_Supplement): 3003.

DOI: https://doi.org/10.1158/1538-7445.AM2011-3003

Published: 15 April 2011

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Journal Articles

Abstract 4791: Genome-wide DNA methylation maps in chronic lymphocytic leukemia cells determined by next-generation sequencing

Lirong Pei, Jeong-Hyeon Choi, Jimei Liu, Gerald Arthur, Jennifer L. Schnabel, Kristen H. Taylor, Charles W. Caldwell, Xinguo Wang, Huidong Shi

Cancer Res (2011) 71 (8_Supplement): 4791.

DOI: https://doi.org/10.1158/1538-7445.AM2011-4791

Published: 15 April 2011

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NARROW

Abstract 2223: Understanding the pro- and anti-tumorigenic microenvironments in syngeneic mice

Autocrine IL6-Mediated Activation of the STAT3–DNMT Axis Silences the TNFα–RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells

Abstract 4493: SF3B1 mutation promotes c-Myc protein stability through aberrant splicing and downregulation of PP2A B56α subunit in chronic lymphocytic leukemia

Abstract 5230: Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia

Abstract LB-282: Dynamic regulation of CD73 expression in cancer associated fibroblasts enforces immunosuppression via a feedforward adenosinergic pathway

Abstract 1997: Inhibition of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia

Abstract 4697: The covalent CDK7 inhibitor THZ1 can counteract apoptotic resistance and suppress the transcription of genes attributed to chronic lymphocytic leukemia malignancy

Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth

Abstract 2191: Transcriptome analysis demonstrates the ability of the bromodomain inhibitor JQ1 to attenuate expression of common oncogenes heterogeneously expressed among chronic lymphocytic leukemia subsets

Abstract 4060: Promoter methylation regulates interferon-γ induced indoleamine 2,3-dioxygenase expression in breast cancer

Abstract 1984: SOCS3 regulates IDO proteasomal degradation and inflammatory signaling in triple negative breast cancer

Abstract 1379: Identification of global DNA methylation signatures in glioblastoma-derived cancer stem cells

Abstract 405: Mbd3 localizes at promoters, gene bodies and enhancers of active genes

Abstract 4012: Large-scale characterization of DNA methylation changes in human gastric carcinomas with and without metastasis

Abstract 5182: Identifying differential gene expression and splicing events in chronic lymphocytic leukemia patients through whole transcriptome profiling

Abstract 5180: Profiling signaling pathways in chronic lymphocytic leukemia using reverse phase protein array

Abstract B63: MBD3 accumulates at promoters and enhancers of active genes

Metabolomic Profiling Reveals Potential Markers and Bioprocesses Altered in Bladder Cancer Progression

Abstract 3003: Targeted bisulfite sequencing of CpG island DNA by solution hybrid selection and next-generation sequencing

Abstract 4791: Genome-wide DNA methylation maps in chronic lymphocytic leukemia cells determined by next-generation sequencing

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