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Journal Articles

Combining Apatinib and Oxaliplatin Remodels the Immunosuppressive Tumor Microenvironment and Sensitizes Desert-Type Gastric Cancer to Immunotherapy

Open Access
Guang-Tan Lin, Cheng Yan, Lu-Jie Li, Xiao-Wen Qiu, Yu-Xuan Zhao, Ju-Li Lin, Yu-Jing Chen, Chuan Feng, Shao-Qiong Chen, Jian-Wei Xie, Chao-Hui Zheng, Sachiyo Nomura, Chang-Ming Huang, Ping Li, Long-Long Cao
Journal: Cancer Research
Cancer Res (2025) 85 (11): 2117–2133.
https://doi.org/10.1158/0008-5472.CAN-24-2697
Published: 02 June 2025
View article titled, Combining Apatinib and Oxaliplatin Remodels the Immunosuppressive Tumor Microenvironment and Sensitizes Desert-Type Gastric Cancer to Immunotherapy
Open the PDF for Combining Apatinib and Oxaliplatin Remodels the Immunosuppressive Tumor Microenvironment and Sensitizes Desert-Type Gastric Cancer to Immunotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract 1560: SCR-A0011, a novel bispecific ADC targeting cMET and B7H3, exhibits potent anti-tumor efficacy

Free
Yayuan Fu, Guangcun Cheng, Hui Zheng, Shuai Wang, Lei Jiang, Chunlei Xia, Huipeng Guo, Xiyuan Wang, Renhong Tang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1560.
https://doi.org/10.1158/1538-7445.AM2025-1560
Published: 21 April 2025
View article titled, Abstract 1560: SCR-A0011, a novel bispecific ADC targeting cMET and B7H3, exhibits potent anti-tumor efficacy
Journal Articles

Abstract 4328: Preclinical development of SCR-A008: A CDH17-targeted ADC for gastrointestinal cancer

Free
Guangcun Cheng, Hui Zheng, Zhiyong Yu, Chunlei Xia, Huipeng Guo, Xiyuan Wang, Yayuan Fu, Renhong Tang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4328.
https://doi.org/10.1158/1538-7445.AM2025-4328
Published: 21 April 2025
View article titled, Abstract 4328: Preclinical development of SCR-A008: A CDH17-targeted ADC for gastrointestinal cancer
Journal Articles

Abstract A001: An open label, phase II trial of ERK inhibition alone and in combination with autophagy inhibition in patients with metastatic cancreatic cancer

Free
Rishi Surana, Hui Zheng, Junning Wang, Micaela Morgado, Lauren K Brais, Kirsten L Bryant, Ashwin Somasundaram, Colin D Weekes, Bruno Bockorny, Mary Linton B Peters, Andrea J Bullock, Jessica A Zerillo, Ahmed A Rattani, Hanna K Sanoff, Jeffrey W Clark, Aparna R Parikh, Matthew B Yurgelun, Anuj Patel, Robert J Mayer, James M Cleary, Peter C Enzinger, Douglas A Rubinson, Nadine J McCleary, Andrea C Enzinger, Sarah E Slater, Kimmie Ng, Thomas A Abrams, Leah Biller, Srivatsan Raghavan, Joseph D Mancias, Jonathan O Nowak, Andrew J Aguirre, Channing J Der, Brian M Wolpin, Kimberley Perez
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): A001.
https://doi.org/10.1158/1538-7445.PANCREATIC24-A001
Published: 15 September 2024
View article titled, Abstract A001: An open label, phase II trial of ERK inhibition alone and in combination with autophagy inhibition in patients with metastatic cancreatic cancer
Journal Articles

Neurotransmitter Receptor HTR2B Regulates Lipid Metabolism to Inhibit Ferroptosis in Gastric Cancer

Available to Purchase
Ru-Hong Tu, Sheng-Ze Wu, Ze-Ning Huang, Qing Zhong, Yin-Hua Ye, Chao-Hui Zheng, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Qi-Yue Chen, Chang-Ming Huang, Mi Lin, Jun Lu, Long-Long Cao, Ping Li
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3868–3885.
https://doi.org/10.1158/0008-5472.CAN-23-1012
Published: 01 December 2023
View article titled, Neurotransmitter Receptor HTR2B Regulates Lipid Metabolism to Inhibit Ferroptosis in Gastric Cancer
Open the PDF for Neurotransmitter Receptor HTR2B Regulates Lipid Metabolism to Inhibit Ferroptosis in Gastric Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract CT155: Long term results and ctDNA correlatives for CAPOX BETR: A multi-center phase II trial of capecitabine, oxaliplatin, bevacizumab and trastuzumab for previously untreated HER2 positive metastatic gastroesophageal adenocarcinoma

Free
Harshabad Singh, Kristen E. Lowder, Kevin Kapner, Ronan J. Kelly, Hui Zheng, Nadine J. McCleary, Thomas A. Abrams, Jennifer A. Chan, Eileen M. Regan, Samuel J. Klempner, Alison M. Hannigan, Lauren K. Brais, Elizabeth A. Andrews, Matthew B. Yurgelun, James M. Cleary, Douglas A. Rubinson, Lauren L. Ritterhouse, Garrett E. Maron, Andrew J. Aguirre, Lu Tan, Pan Du, Jeffrey A. Meyerhardt, Emma Gardecki, Jochen K. Lennerz, Shidong Jia, Brian M. Wolpin, Peter C. Enzinger
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT155.
https://doi.org/10.1158/1538-7445.AM2023-CT155
Published: 14 April 2023
View article titled, Abstract CT155: Long term results and ctDNA correlatives for CAPOX BETR: A multi-center phase II trial of capecitabine, oxaliplatin, bevacizumab and trastuzumab for previously untreated HER2 positive metastatic gastroesophageal adenocarcinoma
Journal Articles

Interventional Optical Imaging Permits Instant Visualization of Pathological Zones of Ablated Tumor Periphery and Residual Tumor Detection

Available to Purchase
Xuefeng Kan, Guanhui Zhou, Feng Zhang, Hongxiu Ji, Hui Zheng, Jeffrey Forris Beecham Chick, Karim Valji, Chuansheng Zheng, Xiaoming Yang
Journal: Cancer Research
Cancer Res (2021) 81 (17): 4594–4602.
https://doi.org/10.1158/0008-5472.CAN-21-1040
Published: 01 September 2021
View article titled, Interventional Optical Imaging Permits Instant Visualization of Pathological Zones of Ablated Tumor Periphery and Residual Tumor Detection
Open the PDF for Interventional Optical Imaging Permits Instant Visualization of Pathological Zones of Ablated Tumor Periphery and Residual Tumor Detection in another window
Journal Articles

Abstract 1649: The E3 ubiquitin ligase EDD regulates platinum resistance and is a novel therapeutic target for epithelial ovarian cancer

Free
Amber T. Bradley, Hui Zheng, Angela Ziebarth, Wayne Sakati, Sande Eier, Gabriel Lopez-Berestein, Anil K. Sood, Charles Landen, Scott T. Eblen
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1649.
https://doi.org/10.1158/1538-7445.AM2011-1649
Published: 15 April 2011
View article titled, Abstract 1649: The E3 ubiquitin ligase EDD regulates platinum resistance and is a novel therapeutic target for epithelial ovarian cancer
Journal Articles

Abstract 3077: The SR protein kinase Clk1 phosphorylates SPF45 and regulates its localization, degradation and alternative splicing activity

Free
Yuying Liu, Adnan Al-Ayoubi, Hui Zheng, Jennifer Bethard, Scott T. Eblen
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3077.
https://doi.org/10.1158/1538-7445.AM2011-3077
Published: 15 April 2011
View article titled, Abstract 3077: The SR protein kinase Clk1 phosphorylates SPF45 and regulates its localization, degradation and alternative splicing activity
Journal Articles

Human epithelial cancer cells produce Ig alpha heavy chain to promote the access of S phase passing through mitosis and growth of cancer cells

Free
Hui Zheng, Ming Li, Wei Ren, Liang Zeng, Duo Sha Hu, Ming Tang, Ying Shi, Zigang Dong, Ya Cao
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 624.
Published: 15 April 2006
View article titled, Human epithelial cancer cells produce Ig alpha heavy chain to promote the access of S phase passing through mitosis and growth of cancer cells
Journal Articles

Expression and secretion of immunoglobulin alpha heavy chain by human epithelial cancer cells

Free
Hui Zheng, Wei Ren, Liang Zeng, Ying Shi, Lian Zhen Wang, Wei Luo, Haidan Liu, Ya Cao
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1156.
Published: 01 May 2005
View article titled, Expression and secretion of immunoglobulin alpha heavy chain by human epithelial cancer cells