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Journal Articles

Abstract 2936: Preclinical characterization of XB371, a novel anti-tissue factor antibody-drug conjugate

Kathleen Gogas, Brian A. Mendelsohn, Marlene Hennessy, Hui Zhao, Jeffrey Higaki, Maxine Bauzon, Fangjiu Zhang, Stepan Chuprakov, Robyn Barfield, Penelope Drake, Seema Kantak
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2936.
https://doi.org/10.1158/1538-7445.AM2025-2936
Published: 21 April 2025
View articletitled, Abstract 2936: Preclinical characterization of XB371, a novel anti-tissue factor antibody-drug conjugate
Journal Articles

Abstract 3775: Liquid biopsy for therapy planning in clinically N0 head and neck cancer (LiC0HN) - A personalized cell-free tumor DNA analysis for patients with HNSCC

Susanne Flach, Arif Surani, Ze Zhou, Hui Zhao, Paulius Mennea, Fazlur Talukdar, Grainne McAndrew, Celina Greger, Christoph Walz, Philipp Jurmeister, Axel Lechner, Christoph Reichel, Olivier Gires, Martin Canis, Philipp Baumeister, Nitzan Rosenfeld, Amit Roshan
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3775.
https://doi.org/10.1158/1538-7445.AM2025-3775
Published: 21 April 2025
View articletitled, Abstract 3775: Liquid biopsy for therapy planning in clinically N0 head and neck cancer (LiC0HN) - A personalized cell-free tumor DNA analysis for patients with HNSCC
Journal Articles

Abstract 4550: Dried blood sot sampling as a minimally invasive and accessible method for investigating circulating tumor DNA in diverse cancer settings

Amit Roshan, Fazlur R. Talukdar, Angela An, Emma-Jane Ditter, Ze Zhou, Paulius D. Mennea, Linfang Wu, Maria C. Neofytou, Anita Balakrishnan, Claire M. Connell, Gabriel Funingana, Giovanni Codacci-Pisanelli, Girma Mulisa, Tamrat Abebe, Constanza Linossi, Hui Zhao, Wendy N. Cooper, Huiqi Yang, Rajesh Jena, James D. Brenton, Pippa Corrie, Rebecca C. Fitzgerald, Simon Pacey, Richard Baird, Nitzan Rosenfeld
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4550.
https://doi.org/10.1158/1538-7445.AM2025-4550
Published: 21 April 2025
View articletitled, Abstract 4550: Dried blood sot sampling as a minimally invasive and accessible method for investigating circulating tumor DNA in diverse cancer settings
Journal Articles

Abstract 4631: Deciphering immunotherapy response variability and immune-related toxicities through longitudinal multimodal ctDNA analysis in advanced melanoma

Zhao Cheng, Sarah McDonald, Hannah Thomas, Ze Zhou, Paulius Mennea, Haichao wang, Dmitry Shcherbo, Christina Zhang, Grainne McAndrew, Fazlur Talukdar, Wendy N. Cooper, Hui Zhao, Nitzan Rosenfeld, Philippa G. Corrie, Amit Roshan
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4631.
https://doi.org/10.1158/1538-7445.AM2025-4631
Published: 21 April 2025
View articletitled, Abstract 4631: Deciphering immunotherapy response variability and immune-related toxicities through longitudinal multimodal ctDNA analysis in advanced melanoma
Journal Articles

Abstract 5679: A novel approach for antibody affinity maturation using AI-driven mutation prediction

Yiran Li, Hao Peng, Hui Zhao, Xiaoyi Han, Panpan Zhang, Jinying Ning, Feng Hao
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5679.
https://doi.org/10.1158/1538-7445.AM2025-5679
Published: 21 April 2025
View articletitled, Abstract 5679: A novel approach for antibody affinity maturation using AI-driven mutation prediction
Journal Articles

Abstract PR012: Ultra-sensitive detection of circulating tumour DNA enriches for patients with higher risk disease in clinically localised prostate cancer

Bernard J. Pope, Gahee Park, Edmund Lau, Jelena Belic, Radoslaw Lach, Anne George, Patrick McCoy, Anne Nguyen, Corrina Grima, Chol-hee Jung, Emma-Jane Ditter, Hui Zhao, David Wedge, Rosalind A Eeles, Daniel Brewer, Andy G. Lynch, Harveer Dev, Christopher M Hovens, Vincent J. Gnanpragasam, Nitzan Rosenfeld, Niall M. Corcoran, Charles E. Massie
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): PR012.
https://doi.org/10.1158/1538-7445.PRCA2023-PR012
Published: 02 June 2023
View articletitled, Abstract PR012: Ultra-sensitive detection of circulating tumour DNA enriches for patients with higher risk disease in clinically localised prostate cancer
Journal Articles

Abstract 1145: PH020-803: an MTA-cooperative and brain-penetrable PRMT5 inhibitor that selectively targets MTAP-deleted tumors

Feng Gao, Bin Liu, Liandong Jing, Yongyong Wu, Pengzhi Zhang, Shuai Yuan, Hui Zhao, Yu Gao, Zhizhong Li, Xiaofan Wang, Yongqi Guo
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1145.
https://doi.org/10.1158/1538-7445.AM2023-1145
Published: 04 April 2023
View articletitled, Abstract 1145: PH020-803: an MTA-cooperative and brain-penetrable PRMT5 inhibitor that selectively targets MTAP-deleted tumors
Journal Articles

Abstract 593: Bispecific antibody against TIGIT and PVRIG enhances antitumor immunity

Jiabei Liang, Xiao Gao, Cong Zhang, Hui Zhao, Hao Peng, Feng Hao, Jinying Ning, Guojin Wu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 593.
https://doi.org/10.1158/1538-7445.AM2023-593
Published: 04 April 2023
View articletitled, Abstract 593: Bispecific antibody against TIGIT and PVRIG enhances antitumor immunity
Journal Articles

Abstract 592: Therapeutical antibody against LILRB2 enhances antitumor immunity by reprogramming M2 macrophage

Chen Su, Yanping Feng, Hui Zhao, Meng Zhang, Longtan Luo, Feng Hao, Jinying Ning, Guojin Wu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 592.
https://doi.org/10.1158/1538-7445.AM2023-592
Published: 04 April 2023
View articletitled, Abstract 592: Therapeutical antibody against LILRB2 enhances antitumor immunity by reprogramming M2 macrophage
Journal Articles

Abstract 4005: PH009-1, a highly potent and selective fourth-generation EGFR-TKI overcoming EGFR common mutations and T790M/C797S-mediated resistance in NSCLC

Feng Gao, Bin Liu, YongYong Wu, Liandong Jing, Pengzhi Zhang, Jing Wang, Shuai Yuan, Hui Zhao, Yu Gao, Zhizhong Li, Xiaofan Wang, Yongqi Guo
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4005.
https://doi.org/10.1158/1538-7445.AM2023-4005
Published: 04 April 2023
View articletitled, Abstract 4005: PH009-1, a highly potent and selective fourth-generation EGFR-TKI overcoming EGFR common mutations and T790M/C797S-mediated resistance in NSCLC
Journal Articles

Abstract 574: Depletion of regulatory T cells without interruption of IL-2 signaling by antibody against CD25 for enhancing antitumor immunity

Yuxuan Gao, Feng He, Hao Peng, Kefei Wu, Hui Zhao, Yanpeng Feng, Feng Hao, Guojin Wu, Jinying Ning
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 574.
https://doi.org/10.1158/1538-7445.AM2023-574
Published: 04 April 2023
View articletitled, Abstract 574: Depletion of regulatory T cells without interruption of IL-2 signaling by antibody against CD25 for enhancing antitumor immunity
Journal Articles

Abstract CT543: 18F-FDG PET/CT detects potentially malignant bone metastases in patients with suspected lesions: A prospective clinical trial

Hui Zhao, Yujie Chang, Zhiyuan Jiang, Zhiyu Wang, Shunyi Ruan
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT543.
https://doi.org/10.1158/1538-7445.AM2022-CT543
Published: 15 June 2022
View articletitled, Abstract CT543: 18F-FDG PET/CT detects potentially malignant bone metastases in patients with suspected lesions: A prospective clinical trial
Journal Articles

Abstract 5665: LILRB2 mediates the immune escape of breast tumor cells by degrading HLA-A

Hui Zhao, zhiyuan jiang, zhiyu wang, yujie chang, shunyi ruan
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5665.
https://doi.org/10.1158/1538-7445.AM2022-5665
Published: 15 June 2022
View articletitled, Abstract 5665: LILRB2 mediates the immune escape of breast tumor cells by degrading HLA-A
Journal Articles

Abstract 5300: Therapeutical antibody against TIGIT disrupts inhibitory signaling and restores antitumor immunity

Hui Zhao, Meng Zhang, Zhengcheng Guo, Cong Zhang, Shuliang Li, Guojin Wu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5300.
https://doi.org/10.1158/1538-7445.AM2022-5300
Published: 15 June 2022
View articletitled, Abstract 5300: Therapeutical antibody against TIGIT disrupts inhibitory signaling and restores antitumor immunity
Journal Articles

Abstract CT170: D-0316 in patients with advanced T790M-positive EGFR-mutant non-small cell lung cancer who progressed on prior EGFR-TKI therapy: results from a phase II study (NCT03861156)

Shun Lu, Yiping Zhang, Guojun Zhang, Jianying Zhou, Shundong Cang, Ying Cheng, Gang Wu, Peiguo Cao, Dongqing Lv, Xiangming Jin, Hong Jian, Chengshui Chen, Guanming Jiang, Panwen Tian, Kai Wang, Hui Zhao, Gongyan Chen, Qun Chen, Cuimin Ding, Junquan Yang, Renhua Guo, Guoping Sun, Bin Wang, Liyan Jiang, Wu Zhuang, Zhe Liu, Jian Fang, Yunpeng Liu, Jian Zhang, Jun Chen, Yueyin Pan, Qitao Yu, Min Zhao, Jiuwei Cui, Dianming Li, Tienan Yi, Zhuang Yu, Yan Yang, Yan Zhang, Xiuyi Zhi, Yunchao Huang, Rong Wu, Liangan Chen, Aimin Zang, Lejie Cao, Qingshan Li, Xiaoling Li, Yong Song, Donglin Wang, Shucai Zhang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT170.
https://doi.org/10.1158/1538-7445.AM2021-CT170
Published: 01 July 2021
View articletitled, Abstract CT170: D-0316 in patients with advanced T790M-positive EGFR-mutant non-small cell lung cancer who progressed on prior EGFR-TKI therapy: results from a phase II study (NCT03861156)
Journal Articles

Abstract SS1-10: Impact of Medicaid expansion on racial disparities in time to adjuvant chemotherapy administration among breast cancer (BC) patients

Mariana Chavez-MacGregor, Xiudong Lei, Hui Zhao, Tina Shih, Sharon H Giordano
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): SS1-10.
https://doi.org/10.1158/1538-7445.SABCS20-SS1-10
Published: 15 February 2021
View articletitled, Abstract SS1-10: Impact of Medicaid expansion on racial disparities in time to adjuvant chemotherapy administration among breast cancer (BC) patients
Journal Articles

Abstract 2059: Exploiting machine learning in local treatment strategies in cancer patients with bone metastases: A real world clinical trial

Hui Zhao, zhiyu wang, jing Sun, yifeng Gu, mengdi Yang, guangyu Yao
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2059.
https://doi.org/10.1158/1538-7445.AM2020-2059
Published: 15 August 2020
View articletitled, Abstract 2059: Exploiting machine learning in local treatment strategies in cancer patients with bone metastases: A real world clinical trial
Journal Articles

Abstract 4257: Detection of bone marrow metastases: Comparison of functional magnetic resonance imaging with bone marrow biopsy and aspiration

Hui Zhao, Zhiyu Wang, Yue Hua Li
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4257.
https://doi.org/10.1158/1538-7445.AM2020-4257
Published: 15 August 2020
View articletitled, Abstract 4257: Detection of bone marrow metastases: Comparison of functional magnetic resonance imaging with bone marrow biopsy and aspiration
Journal Articles

Abstract 6011: Mesenchymal stem cells promote PD-L1 expression in lung cancer cells

Hui Zhao, Hui Yang, Jinqiu Sun, Guoqiang Liang, Qianqian Zhao, Xiufang Zhang, Shengxian Liang, Rui Guo, Li Zhong
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6011.
https://doi.org/10.1158/1538-7445.AM2020-6011
Published: 15 August 2020
View articletitled, Abstract 6011: Mesenchymal stem cells promote PD-L1 expression in lung cancer cells
Journal Articles

ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia

Yi Shu, Yi Wang, Wen-Qiong Lv, Dan-Yi Peng, Juan Li, Hang Zhang, Guang-Jie Jiang, Bi-Jie Yang, Shan Liu, Jia Zhang, Yan-Hua Chen, Shi Tang, Ke-Xing Wan, Jun-Tao Yuan, Wei Guo, Guo Fu, Xin-Kun Qi, Zhi-Dai Liu, Hai-Yan Liu, Chao Yang, Ling-Huan Zhang, Fang-Jie Liu, Jie Yu, Peng-Hui Zhang, Bin Qu, Hui Zhao, Tong-Chuan He, Lin Zou
Journal: Cancer Research
Cancer Res (2020) 80 (5): 988–998.
https://doi.org/10.1158/0008-5472.CAN-19-1471
Published: 02 March 2020
View articletitled, ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia
Open the PDF for ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia in another window
Includes: Supplementary data