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Journal Articles

Abstract C024: Quantitative mass spectrometry-based multi-omic profiling to overcome drug resistance in pancreatic cancer post KRAS G12D inhibition

Free
Qijia Yu, Nicole Sindoni, Huan Zhang, Ziyue Li, Joao A. Paulo, Andrew J. Aguirre, Joseph D. Mancias
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): C024.
https://doi.org/10.1158/1538-7445.PANCREATIC24-C024
Published: 15 September 2024
View articletitled, Abstract C024: Quantitative mass spectrometry-based multi-omic profiling to overcome drug resistance in pancreatic cancer post KRAS G12D inhibition
Journal Articles

Abstract C018: Targeting KRAS inhibitor resistance by ferroptosis induction in PDAC

Free
Aparna Padhye, Qijia Yu, Nicole Sindoni, Huan Zhang, Julien Dilly, Hanrong Feng, Andrew Aguirre, Joseph Mancias
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): C018.
https://doi.org/10.1158/1538-7445.PANCREATIC24-C018
Published: 15 September 2024
View articletitled, Abstract C018: Targeting KRAS inhibitor resistance by ferroptosis induction in PDAC
Journal Articles

Abstract C032: De novo pyrimidine biosynthesis inhibition synergizes with BCL-XL targeting in pancreatic cancer

Free
huan zhang, Qijia yu, Naiara Santana-Codina, Clara Poupault, Claudia Campos, Xingping Qin, Aparna Padhye, Nicole Sindoni, Miljan Kuljanin, Junning Wang, Matthew J. Dorman, Andrew J. Aguirre, Stephanie K. Dougan, Kristopher A. Sarosiek, Joseph D. Mancias
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): C032.
https://doi.org/10.1158/1538-7445.PANCREATIC24-C032
Published: 15 September 2024
View articletitled, Abstract C032: De novo pyrimidine biosynthesis inhibition synergizes with BCL-XL targeting in pancreatic cancer
Journal Articles

ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma

Open Access
Yan Sun, Liang Zhu, Pian Liu, Huan Zhang, Feng Guo, Xin Jin
Journal: Cancer Research
Cancer Res (2023) 83 (12): 2034–2051.
https://doi.org/10.1158/0008-5472.CAN-22-3105
Published: 15 June 2023
View articletitled, ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma
Open the PDF for ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Pharmacological Targeting of Androgen Receptor Elicits Context-Specific Effects in Estrogen Receptor–Positive Breast Cancer

Open Access
Lixuan Wei, Huanyao Gao, Jia Yu, Huan Zhang, Thanh Thanh L. Nguyen, Yayun Gu, Marie R. Passow, Jodi M. Carter, Bo Qin, Judy C. Boughey, Matthew P. Goetz, Richard M. Weinshilboum, James N. Ingle, Liewei Wang
Journal: Cancer Research
Cancer Res (2023) 83 (3): 456–470.
https://doi.org/10.1158/0008-5472.CAN-22-1016
Published: 03 February 2023
View articletitled, Pharmacological Targeting of Androgen Receptor Elicits Context-Specific Effects in Estrogen Receptor–Positive Breast Cancer
Open the PDF for Pharmacological Targeting of Androgen Receptor Elicits Context-Specific Effects in Estrogen Receptor–Positive Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract A075: NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins

Free
Naiara Santana-Codina, Huan Zhang, Maria Quiles del Rey, Kevin S. Kapner, Ajami Gikandi, Callum Malcolm, Clara Poupault, Miljan Kuljanin, Kristen John, Douglas E. Biancur, Brandon Chen, Nupur Das, Kristen Lowder, Connor J. Hennessey, Wesley Huang, Annan Yang, Yatrik M. Shah, Jonathan A. Nowak, Andrew J. Aguirre, Joseph D. Mancias
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): A075.
https://doi.org/10.1158/1538-7445.PANCA22-A075
Published: 15 November 2022
View articletitled, Abstract A075: NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
Journal Articles

Abstract P5-01-07: Patient-derived xenografts (PDXs) generated from hormone receptor-positive breast cancer (BC) before and after cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) treatment: Initial findings from the PROMISE study

Free
Jia Yu, Vera J. Suman, Jun He, Jason P. Sinnwell, Ann M. Moyer, Bo Qin, Yayun Gu, Huan Zhang, Jodi M. Carter, Krishna R. Kalari, Brendan P. McMenomy, Minetta C. Liu, Tufia C. Haddad, Kathryn J. Ruddy, Fergus J. Couch, Alvaro Moreno-Aspitia, Donald W. Northfelt, Richard Weinshilboum, Ciara O'Sullivan, Matthew P. Goetz, Liewei Wang
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-01-07.
https://doi.org/10.1158/1538-7445.SABCS21-P5-01-07
Published: 15 February 2022
View articletitled, Abstract P5-01-07: Patient-derived xenografts (PDXs) generated from hormone receptor-positive breast cancer (BC) before and after cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) treatment: Initial findings from the PROMISE study
Journal Articles

Abstract PD1-03: Estrogen receptor is a target of enzalutamide in ER+ breast cancer

Free
Lixuan Wei, Jia Yu, Huanyao Gao, Huan Zhang, Thanh Nguyen, Yayun Gu, Richard M. Weinshilboum, James N. Ingle, Liewei Wang
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD1-03.
https://doi.org/10.1158/1538-7445.SABCS21-PD1-03
Published: 15 February 2022
View articletitled, Abstract PD1-03: Estrogen receptor is a target of enzalutamide in ER+ breast cancer
Journal Articles

Abstract PS5-36: Computational modeling of androgen receptor (AR) and estrogen receptor as predictive biomarkers of response to AR agonists and antagonists

Free
Lixuan Wei, Huanyao Gao, Jia Yu, Duan Liu, Huan Zhang, Thanh Nguyen, Marie R Passow, Jodi M Carter, Richard M Weinshilboum, James N Ingle, Liewei Wang
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS5-36.
https://doi.org/10.1158/1538-7445.SABCS20-PS5-36
Published: 15 February 2021
View articletitled, Abstract PS5-36: Computational modeling of androgen receptor (AR) and estrogen receptor as predictive biomarkers of response to AR agonists and antagonists
Journal Articles

ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia

Available to Purchase
Yi Shu, Yi Wang, Wen-Qiong Lv, Dan-Yi Peng, Juan Li, Hang Zhang, Guang-Jie Jiang, Bi-Jie Yang, Shan Liu, Jia Zhang, Yan-Hua Chen, Shi Tang, Ke-Xing Wan, Jun-Tao Yuan, Wei Guo, Guo Fu, Xin-Kun Qi, Zhi-Dai Liu, Hai-Yan Liu, Chao Yang, Ling-Huan Zhang, Fang-Jie Liu, Jie Yu, Peng-Hui Zhang, Bin Qu, Hui Zhao, Tong-Chuan He, Lin Zou
Journal: Cancer Research
Cancer Res (2020) 80 (5): 988–998.
https://doi.org/10.1158/0008-5472.CAN-19-1471
Published: 02 March 2020
View articletitled, ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia
Open the PDF for ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia in another window
Includes: Supplementary data
Journal Articles

LASP1 Is a HIF1α Target Gene Critical for Metastasis of Pancreatic Cancer

Free
Tiansuo Zhao, He Ren, Jing Li, Jing Chen, Huan Zhang, Wen Xin, Yan Sun, Lei Sun, Yongwei Yang, Junwei Sun, Xiuchao Wang, Song Gao, Chongbiao Huang, Huafeng Zhang, Shengyu Yang, Jihui Hao
Journal: Cancer Research
Cancer Res (2015) 75 (1): 111–119.
https://doi.org/10.1158/0008-5472.CAN-14-2040
Published: 04 January 2015
View articletitled, LASP1 Is a HIF1α Target Gene Critical for Metastasis of Pancreatic Cancer
Open the PDF for LASP1 Is a HIF1α Target Gene Critical for Metastasis of Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Hypoxia-Inducible Factor-1 Promotes Pancreatic Ductal Adenocarcinoma Invasion and Metastasis by Activating Transcription of the Actin-Bundling Protein Fascin

Free
Xiao Zhao, Song Gao, He Ren, Wei Sun, Huan Zhang, Jianwei Sun, Shengyu Yang, Jihui Hao
Journal: Cancer Research
Cancer Res (2014) 74 (9): 2455–2464.
https://doi.org/10.1158/0008-5472.CAN-13-3009
Published: 30 April 2014
View articletitled, Hypoxia-Inducible Factor-1 Promotes Pancreatic Ductal Adenocarcinoma Invasion and Metastasis by Activating Transcription of the Actin-Bundling Protein Fascin
Open the PDF for Hypoxia-Inducible Factor-1 Promotes Pancreatic Ductal Adenocarcinoma Invasion and Metastasis by Activating Transcription of the Actin-Bundling Protein Fascin in another window
Includes: Supplementary data