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Hualiang Jiang
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Journal Articles

Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR–ABL–Positive Leukemia

Ziwei Luo, Chencen Lin, Chuwei Yu, Changxian Yuan, Wenyong Wu, Xiaowei Xu, Renhong Sun, Yan Jia, Yafang Wang, Jie Shen, Dingyan Wang, Sinan Wang, Hualiang Jiang, Biao Jiang, Xiaobao Yang, Chengying Xie
Journal: Cancer Research
Cancer Res (2025) 85 (1): 101–117.
https://doi.org/10.1158/0008-5472.CAN-24-1093
Published: 02 January 2025
View article titled, Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR–ABL–Positive Leukemia
Open the PDF for Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR–ABL–Positive Leukemia in another window
Includes: Supplementary data
Journal Articles

PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells

Jiangmei Li, Zhen Gao, Dan Zhao, Lunfeng Zhang, Xinhua Qiao, Yingying Zhao, Hong Ding, Panpan Zhang, Junyan Lu, Jia Liu, Hualiang Jiang, Cheng Luo, Chang Chen
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (22): 6253–6266.
https://doi.org/10.1158/0008-5472.CAN-17-0484
Published: 14 November 2017
View article titled, PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells
Open the PDF for PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification

Wenyi Sun, Zuoquan Xie, Yifu Liu, Dan Zhao, Zhixiang Wu, Dadong Zhang, Hao Lv, Shuai Tang, Nan Jin, Hualiang Jiang, Minjia Tan, Jian Ding, Cheng Luo, Jian Li, Min Huang, Meiyu Geng
Journal: Cancer Research
Cancer Res (2015) 75 (22): 4923–4936.
https://doi.org/10.1158/0008-5472.CAN-15-1023
Published: 15 November 2015
View article titled, JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification
Open the PDF for JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification in another window
Includes: Multimedia, Supplementary data
Journal Articles

[6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A4 Hydrolase

Chul-Ho Jeong, Ann M. Bode, Angelo Pugliese, Yong-Yeon Cho, Hong-Gyum Kim, Jung-Hyun Shim, Young-Jin Jeon, Honglin Li, Hualiang Jiang, Zigang Dong
Journal: Cancer Research
Cancer Res (2009) 69 (13): 5584–5591.
https://doi.org/10.1158/0008-5472.CAN-09-0491
Published: 01 July 2009
View article titled, [6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A<sub>4</sub> Hydrolase
Open the PDF for [6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A<sub>4</sub> Hydrolase in another window
Includes: Supplementary data
Journal Articles

Naturally occurring homoisoflavonoids function as potent protein tyrosine kinases inhibitors by c-Src-based high-throughput screening

Hua Xie, Ligen Lin, Honglin Li, Linjiang Tong, Chunping Tang, Changqiang Ke, Liping Lin, Meiyu Geng, Hualiang Jiang, Weimin Zhao, Yang Ye, Jian Ding
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4861.
Published: 01 May 2008
View article titled, Naturally occurring homoisoflavonoids function as potent protein tyrosine kinases inhibitors by c-Src-based high-throughput screening