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Journal Articles

Abstract 3803: CRISPR screening identifies methionine synthase as a potential therapeutic target in KRAS-driven NSCLC

Wenping Wang, Samuel Wang, Ioana Dobrescu, Hyungsin Kim, Kyle Nunn, Joel Lee, Joshua Martorelli, Fuqian Shi, Eduardo Lopes, Victoria Silva, Hua Zhong, Zhixian Hu, Daniel Herranz, Chang Chan, Eileen White, Jessie Yanxiang Guo
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3803.
https://doi.org/10.1158/1538-7445.AM2025-3803
Published: 21 April 2025
View articletitled, Abstract 3803: CRISPR screening identifies methionine synthase as a potential therapeutic target in KRAS-driven NSCLC
Journal Articles

Abstract 7390: Learning Llama Agents for medical record analysis and standardization

David Hein, Alana Christie, Hua Zhong, Ellen Araj, James Brugarolas, Lindsay Cowell, Payal Kapur, Andrew Jamieson
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7390.
https://doi.org/10.1158/1538-7445.AM2024-7390
Published: 22 March 2024
View articletitled, Abstract 7390: Learning Llama Agents for medical record analysis and standardization
Journal Articles

Abstract 6153: Proteome-wide association study and functional validation identify novel protein markers for pancreatic ductal adenocarcinoma

Jingjing Zhu, Ke Wu, Shuai Liu, Alexandra Masca, Hua Zhong, Tai Yang, Dalia H. Ghoneim, Praveen Surendran, Tanxin Liu, Qizhi Yao, Tao Liu, Sarah Fahle, Adam Butterworth, Md A. Alam, Jaydutt V. Vadgama, Youping Deng, Hong-Wen Deng, Chong Wu, Yong Wu, Lang Wu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6153.
https://doi.org/10.1158/1538-7445.AM2024-6153
Published: 22 March 2024
View articletitled, Abstract 6153: Proteome-wide association study and functional validation identify novel protein markers for pancreatic ductal adenocarcinoma
Journal Articles

Abstract 5352: SOX9-dependent immune microenvironment remodeling drives KRAS-induced lung adenocarcinoma progression

Dinoop Ravindran Menon, Hua Zhong, Shridar Ganesan, Hatim Sabaawy, Sharon Pine
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5352.
https://doi.org/10.1158/1538-7445.AM2024-5352
Published: 22 March 2024
View articletitled, Abstract 5352: SOX9-dependent immune microenvironment remodeling drives KRAS-induced lung adenocarcinoma progression
Journal Articles

Abstract 2600: BBOX1 is a novel tumor suppressor in kidney cancer

Chengheng Liao, Liwei Jia, Hua Zhong, Lianxin Hu, Payal Kapur, James Brugarolas, Qing Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2600.
https://doi.org/10.1158/1538-7445.AM2023-2600
Published: 04 April 2023
View articletitled, Abstract 2600: BBOX1 is a novel tumor suppressor in kidney cancer
Journal Articles

Inflammatory Breast Cancer Promotes Development of M2 Tumor-Associated Macrophages and Cancer Mesenchymal Cells through a Complex Chemokine Network

Amanda Valeta-Magara, Abhilash Gadi, Viviana Volta, Beth Walters, Rezina Arju, Shah Giashuddin, Hua Zhong, Robert J. Schneider
Journal: Cancer Research
Cancer Res (2019) 79 (13): 3360–3371.
https://doi.org/10.1158/0008-5472.CAN-17-2158
Published: 01 July 2019
View articletitled, Inflammatory Breast Cancer Promotes Development of M2 Tumor-Associated Macrophages and Cancer Mesenchymal Cells through a Complex Chemokine Network
Open the PDF for Inflammatory Breast Cancer Promotes Development of M2 Tumor-Associated Macrophages and Cancer Mesenchymal Cells through a Complex Chemokine Network in another window
Includes: Supplementary data
Journal Articles

Schwann Cells Augment Cell Spreading and Metastasis of Lung Cancer

Yan Zhou, Galina V. Shurin, Hua Zhong, Yuri L. Bunimovich, Baohui Han, Michael R. Shurin
Journal: Cancer Research
Cancer Res (2018) 78 (20): 5927–5939.
https://doi.org/10.1158/0008-5472.CAN-18-1702
Published: 15 October 2018
View articletitled, Schwann Cells Augment Cell Spreading and Metastasis of Lung Cancer
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Journal Articles

Abstract 4798: Genomic alterations in ERBB2 define a subset of pleomorphic invasive lobular breast cancer

Kim M. Hirshfield, Renee Sanders, Heather K. Feld, Nicola Barnard, Li Liang, Hua Zhong, Gyan Bhanot, Amrik S. Sahota, Andrew Brooks, Lorna Rodriguez-Rodriguez, Shridar Ganesan
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4798.
https://doi.org/10.1158/1538-7445.AM2015-4798
Published: 01 August 2015
View articletitled, Abstract 4798: Genomic alterations in ERBB2 define a subset of pleomorphic invasive lobular breast cancer
Journal Articles

Abstract 223: Generation of single cell-derived normal, benign and cancer mini-prostates from primary patient-derived tissues

Monica Bartucci, Michele Patrizii, Eric Huselid, Shamila Yussuf, Nitu Bansal, Kathleen Flaherty, Denis Tolkunov, Hua Zhong, Mark N. Stein, Joseph Bertino, Robert DiPaola, Isaac Kim, Hatem E. Sabaawy
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 223.
https://doi.org/10.1158/1538-7445.AM2015-223
Published: 01 August 2015
View articletitled, Abstract 223: Generation of single cell-derived normal, benign and cancer mini-prostates from primary patient-derived tissues
Journal Articles

Abstract 2835: MDM2 antagonist-based therapeutic response is discriminated by a 4-gene signature in acute myeloid leukemia patients

Hua Zhong, Gong Chen, Lori Jukofsky, David Geho, Sung Won Han, Fabian Birzele, Sabine Bader, Lucia Himmelein, James Cai, Zayed Albertyn, Mark Rothe, Laurent Essioux, Helmut Burtscher, Steven A. Middleton, Lin-Chi Chen, Markus Dangl, William E. Pierceall, Gwen Nichols
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2835.
https://doi.org/10.1158/1538-7445.AM2015-2835
Published: 01 August 2015
View articletitled, Abstract 2835: MDM2 antagonist-based therapeutic response is discriminated by a 4-gene signature in acute myeloid leukemia patients
Journal Articles

Abstract 2233: Rearrangement of ERG and CHD1 genes in prostate cancer as a marker of tumor heterogeneity

Irina V. Tereshchenko, Hua Zhong, Marina Chekmareva, Urmila Santanam, Whitney Petrosky, Noriko Kane-Goldsmith, Jay A. Tischfield, Robert DiPaola
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2233.
https://doi.org/10.1158/1538-7445.AM2014-2233
Published: 01 October 2014
View articletitled, Abstract 2233: Rearrangement of ERG and CHD1 genes in prostate cancer as a marker of tumor heterogeneity
Journal Articles

Abstract 2360: Gene expression profile induced by pregnancy in the breast of premenopausal women

Julia Santucci-Pereira, Anne Zeleniuch-Jacquotte, Yelena Afanasyeva, Hua Zhong, Eric A. Ross, Michael Slifker, Suraj Peri, Ricardo López de Cicco, Yubo Zhai, Irma H. Russo, Theresa Nguyen, Fathima Sheriff, Alan A. Arslan, Pal Bordas, Per Lenner, Janet Åhman, Anna-Stina L. Eriksson, Robert Johansson, Göran Hallmans, Paolo Toniolo, Jose Russo
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2360.
https://doi.org/10.1158/1538-7445.AM2014-2360
Published: 01 October 2014
View articletitled, Abstract 2360: Gene expression profile induced by pregnancy in the breast of premenopausal women
Journal Articles

Abstract LB-138: Autophagy regulator BECN1 acts as a context-dependent tumor suppressor opposing parity-associated and WNT1-driven mammary tumorigenesis

Michelle Cicchini, Rumela Chakrabarti, Sameera Kongara, Sandy Price, Ritu Nahar, Fred Lozy, Hua Zhong, Alexei Vazquez, Yibin Kang, Vassiliki Karantza
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-138.
https://doi.org/10.1158/1538-7445.AM2014-LB-138
Published: 01 October 2014
View articletitled, Abstract LB-138: Autophagy regulator BECN1 acts as a context-dependent tumor suppressor opposing parity-associated and WNT1-driven mammary tumorigenesis
Journal Articles

Abstract 4311: Identification of a subset of peripheral blood cells expressing ALDH1 with chromosomal abnormalities in lung cancer patients suggests these are putative cancer stem cells

Abha Khanna, Tanweer M. Zaidi, Weigong He, Ricardo Fernandez, Hua-Zhong Zhang, Nancy P. Caraway, Reza Mehran, Randa El-Zein, David P. Blowers, Feng Jiang, Ruth L. Katz
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4311.
https://doi.org/10.1158/1538-7445.AM10-4311
Published: 15 April 2010
View articletitled, Abstract 4311: Identification of a subset of peripheral blood cells expressing ALDH1 with chromosomal abnormalities in lung cancer patients suggests these are putative cancer stem cells
Journal Articles

Abstract #519: TRPS-1 gene expression in breast cancer

Jie Qing Chen, Jennifer Litton, Hua-Zhong Zhang, Yijun Wang, James L. Murray III, Carla L Warneke, Neil Berinstein, Ausegul A Sahin, Ruth L Katz, Laszlo Radvanyi
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 519.
Published: 01 May 2009
View articletitled, Abstract #519: TRPS-1 gene expression in breast cancer
Journal Articles

Studies of thioxanenone sulfoxides as hypoxia selective bioreductive prodrugs

Chul-Hoon Kwon, Hua-Zhong He, Sang-ki Park, Radhika Venkatraman
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 3967.
Published: 01 May 2007
View articletitled, Studies of thioxanenone sulfoxides as hypoxia selective bioreductive prodrugs
Journal Articles

HIF-1 alpha activated tumor specific expression of survivin gene is mediated by a novel transcriptional mechanism

Prasanthi Karna, Zehong Cao, Hua Zhong, William Wood, Fengzhi Li, Lily Yang
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4914.
Published: 01 May 2007
View articletitled, HIF-1 alpha activated tumor specific expression of survivin gene is mediated by a novel transcriptional mechanism
Journal Articles

Cross-talk between EGFR and HIF-1 alpha signaling pathways increases resistance to apoptosis under normoxic conditions by upregulating survivin in human breast cancer cells

Xianghong Peng, Prasanthi Karna, Zehong Cao, Hua Zhong, Bing Hua Jiang, William C. Wood, Lily Yang
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1038.
Published: 01 May 2005
View articletitled, Cross-talk between EGFR and HIF-1 alpha signaling pathways increases resistance to apoptosis under normoxic conditions by upregulating survivin in human breast cancer cells
Journal Articles

Interstitial pressure stress augments hypoxia induced hypoxia-inducible factor 1alpha: Results from an in vitro experimental model

Meredith Holley, Margaret Willard, Ruoxiang Wang, Jonathan W. Simons, Hua Zhong
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 262–263.
Published: 01 May 2005
View articletitled, Interstitial pressure stress augments hypoxia induced hypoxia-inducible factor 1alpha: Results from an in vitro experimental model
Journal Articles

Impact of Epidermal Growth Factor Receptor Expression on Survival and Pattern of Relapse in Patients with Advanced Head and Neck Carcinoma

K. Kian Ang, Brian A. Berkey, Xiaoyu Tu, Hua-Zhong Zhang, Ruth Katz, Elizabeth H. Hammond, Karen K. Fu, Luka Milas
Journal: Cancer Research
Cancer Res (2002) 62 (24): 7350–7356.
Published: 15 December 2002
View articletitled, Impact of Epidermal Growth Factor Receptor Expression on Survival and Pattern of Relapse in Patients with Advanced Head and Neck Carcinoma
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