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Journal Articles

Abstract 2297: Profound anti-tumor efficacy of dual CDK7 and PD1 blockade in novel syngeneic prostate cancer models

David Wise, Luiza Doro Pereira, Jiansheng Wu, Victor R. Adorno Febles, Jonathan Melamed, Fang-Ming Deng, Hua Zhang, Kwok-Kin Wong
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2297.
https://doi.org/10.1158/1538-7445.AM2022-2297
Published: 15 June 2022
View article titled, Abstract 2297: Profound anti-tumor efficacy of dual CDK7 and PD1 blockade in novel syngeneic prostate cancer models
Journal Articles

Abstract 759: Analytical performance of a novel next generation sequencing assay for myeloid MRD

Hua Zhang, Xinzhan Peng, Guobin Luo, Annie Kraltcheva, David Mandelman, Michelle Swimley, Eli Pazol, Jose Espinoza, Scott Mitchell, Bo Ding, Ratnesh Singh, Doug Fenger, Na Li, Andrew Hatch, Vadim Mozhayskiy, Steven Roman, Sophie Rozenzhak
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 759.
https://doi.org/10.1158/1538-7445.AM2022-759
Published: 15 June 2022
View article titled, Abstract 759: Analytical performance of a novel next generation sequencing assay for myeloid MRD
Journal Articles

Abstract P1-21-04: The real word study on clinical features and prognostic factors of Chinese breast cancer patients with brain metastasis

Tao Wang, Huiqiang Zhang, Feng Li, Xia Wu, Jinmei Zhou, Shao hua Zhang, Li Bian, Ze fei Jiang
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-21-04.
https://doi.org/10.1158/1538-7445.SABCS21-P1-21-04
Published: 15 February 2022
View article titled, Abstract P1-21-04: The real word study on clinical features and prognostic factors of Chinese breast cancer patients with brain metastasis
Journal Articles

Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

Han Han, Shuai Li, Ting Chen, Michael Fitzgerald, Shengwu Liu, Chengwei Peng, Kwan Ho Tang, Shougen Cao, Johara Chouitar, Jiansheng Wu, David Peng, Jiehui Deng, Zhendong Gao, Theresa E. Baker, Fei Li, Hua Zhang, Yuanwang Pan, Hailin Ding, Hai Hu, Val Pyon, Cassandra Thakurdin, Eleni Papadopoulos, Sittinon Tang, Francois Gonzalvez, Haiquan Chen, Victor M. Rivera, Rachael Brake, Sylvie Vincent, Kwok-Kin Wong
Journal: Cancer Research
Cancer Res (2021) 81 (20): 5311–5324.
https://doi.org/10.1158/0008-5472.CAN-21-1526
Published: 15 October 2021
View article titled, Targeting <em>HER2</em> Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib
Open the PDF for Targeting <em>HER2</em> Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib in another window
Includes: Supplementary data
Journal Articles

Alteration of MDM2 by the Small Molecule YF438 Exerts Antitumor Effects in Triple-Negative Breast Cancer

Peipei Shan, Feifei Yang, Hongzhao Qi, Yunjie Hu, Sujie Zhu, Zhenqing Sun, Zhe Zhang, Chuanxiao Wang, Caixia Hou, Jie Yu, Lirong Wang, Zhixia Zhou, Peifeng Li, Hua Zhang, Kun Wang
Journal: Cancer Research
Cancer Res (2021) 81 (15): 4027–4040.
https://doi.org/10.1158/0008-5472.CAN-20-0922
Published: 01 August 2021
View article titled, Alteration of MDM2 by the Small Molecule YF438 Exerts Antitumor Effects in Triple-Negative Breast Cancer
Open the PDF for Alteration of MDM2 by the Small Molecule YF438 Exerts Antitumor Effects in Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract PS13-14: A randomized, opened, phase II trial assessing the efficacy and safety of ATH-TH(doxorubicin/docetaxel/trastuzumab followed by docetaxel/trastuzumab) versus TCH(docetaxel/carboplatin/trastuzumab) as neoadjuvant treatment in HER2-positive breast cancer

Tao Wang, Jin-Mei Zhou, Xiao-Peng Hao, Hui-Qaing Zhang, Shao-Hua Zhang, Li Bian, Ze-Fei Jiang
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS13-14.
https://doi.org/10.1158/1538-7445.SABCS20-PS13-14
Published: 15 February 2021
View article titled, Abstract PS13-14: A randomized, opened, phase II trial assessing the efficacy and safety of ATH-TH(doxorubicin/docetaxel/trastuzumab followed by docetaxel/trastuzumab) versus TCH(docetaxel/carboplatin/trastuzumab) as neoadjuvant treatment in HER2-positive breast cancer
Journal Articles

Epigenetic CRISPR Screens Identify Npm1 as a Therapeutic Vulnerability in Non–Small Cell Lung Cancer

Fei Li, Wai-Lung Ng, Troy A. Luster, Hai Hu, Vladislav O. Sviderskiy, Catríona M. Dowling, Kate E.R. Hollinshead, Paula Zouitine, Hua Zhang, Qingyuan Huang, Michela Ranieri, Wei Wang, Zhaoyuan Fang, Ting Chen, Jiehui Deng, Kai Zhao, Hon-Cheong So, Alireza Khodadadi-Jamayran, Mousheng Xu, Angeliki Karatza, Val Pyon, Shuai Li, Yuanwang Pan, Kristen Labbe, Christina Almonte, John T. Poirier, George Miller, Richard Possemato, Jun Qi, Kwok-Kin Wong
Journal: Cancer Research
Cancer Res (2020) 80 (17): 3556–3567.
https://doi.org/10.1158/0008-5472.CAN-19-3782
Published: 02 September 2020
View article titled, Epigenetic CRISPR Screens Identify <em>Npm1</em> as a Therapeutic Vulnerability in Non–Small Cell Lung Cancer
Open the PDF for Epigenetic CRISPR Screens Identify <em>Npm1</em> as a Therapeutic Vulnerability in Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 4463: Tumor-derived cell-free DNA from bronchoalveolar lavage fluid (BALF): A potential liquid biopsy analysis in lung cancer patients

Yuhua Gong, Xinyu Zhang, Chun Li, Weiran Wang, Maosong Ye, Yancheng Zhao, Xin Yi, Yaping Xu, Qin Hu, Yanfang Guan, Ling Yang, Xuefeng Xia, Min Zhou, Jian'an Huang, Hua Zhang, Tao Ren, Qian Shen, Kai Wang, Yingyong Hou, Xin Zhang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4463.
https://doi.org/10.1158/1538-7445.AM2019-4463
Published: 01 July 2019
View article titled, Abstract 4463: Tumor-derived cell-free DNA from bronchoalveolar lavage fluid (BALF): A potential liquid biopsy analysis in lung cancer patients
Journal Articles

NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model

Yan Liu, Yuyang Li, Shengwu Liu, Dennis O. Adeegbe, Camilla L. Christensen, Max M. Quinn, Ruben Dries, Shiwei Han, Kevin Buczkowski, Xiaoen Wang, Ting Chen, Peng Gao, Hua Zhang, Fei Li, Peter S. Hammerman, James E. Bradner, Steven N. Quayle, Kwok-Kin Wong
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (13): 3709–3717.
https://doi.org/10.1158/0008-5472.CAN-18-0161
Published: 01 July 2018
View article titled, NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model
Open the PDF for NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model in another window
Includes: Supplementary data
Journal Articles

Abstract 14: Anticancer activities of terpenoid compounds isolated from the plant centipeda minma against nasopharyngeal carcinoma cells

Bei-bei Liu, Kui-yuan Zhu, Chi-on Chan, Ling-Hua Zhang, Daniel Kam-Wah Mok, Si-bao Chen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 14.
https://doi.org/10.1158/1538-7445.AM2017-14
Published: 01 July 2017
View article titled, Abstract 14: Anticancer activities of terpenoid compounds isolated from the plant <em>centipeda minma</em> against nasopharyngeal carcinoma cells
Journal Articles

Abstract 185: Role of phosphorylation in Lmtk3 activation and its contribution in breast cancer progression

Giulia Lucchiari, Hua Zhang, Joao Nunes, Yichen Xu, Arnhild Grothey, Justin Stebbing, Georgios Giamas
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 185.
https://doi.org/10.1158/1538-7445.AM2016-185
Published: 15 July 2016
View article titled, Abstract 185: Role of phosphorylation in Lmtk3 activation and its contribution in breast cancer progression
Journal Articles

Abstract 432: Macrophage promotes EMT in gastric cancer through activating CXCR2 signaling

Chang-Hua Zhang, Guangkai Xia
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 432.
https://doi.org/10.1158/1538-7445.AM2015-432
Published: 01 August 2015
View article titled, Abstract 432: Macrophage promotes EMT in gastric cancer through activating CXCR2 signaling
Journal Articles

Abstract 3308: Enhanced expression of galectin-3 isassociated with the alternative activation of macrophages and development oflung fibrosis following radiation

Weiling Zhao, Jing-Hua Zhang, Ingrid J. Lopes
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3308.
https://doi.org/10.1158/1538-7445.AM2015-3308
Published: 01 August 2015
View article titled, Abstract 3308: Enhanced expression of galectin-3 isassociated with the alternative activation of macrophages and development oflung fibrosis following radiation
Journal Articles

Abstract 4707: Genetically engineered NY-ESO-1-specific T cells in HLA-A2+ patients with synovial sarcoma

Melinda S. Merchant, Sandra P. D'Angelo, Hua Zhang, Donna Bernstein, Gwen Binder-Scholl, Tom Holdich, Luca Melchiori, Dan Williams, Marylene Fortin, Yoav Peretz, Jason Howe, Michael Mehler, Bruce A. Hug, Matthew Wright, Stephen Grupp, Paul A. Meyers, William Tap, Bent Jakobsen, Crystal L. Mackall
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4707.
https://doi.org/10.1158/1538-7445.AM2015-4707
Published: 01 August 2015
View article titled, Abstract 4707: Genetically engineered NY-ESO-1-specific T cells in HLA-A2+ patients with synovial sarcoma
Journal Articles

Abstract 1606: Global mapping of tyrosine kinase signalling in breast cancer by combined use of RNAi and SILAC quantitative proteomics

Hua Zhang, Justin Stebbing, Yichen Xu, Georgios Giamas
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1606.
https://doi.org/10.1158/1538-7445.AM2014-1606
Published: 01 October 2014
View article titled, Abstract 1606: Global mapping of tyrosine kinase signalling in breast cancer by combined use of RNAi and SILAC quantitative proteomics
Journal Articles

Abstract 3794: The role of LMTK3 in breast cancer cell growth and invasion.

Yichen Xu, Aleksandra Filipovic, Hua Zhang, Lei Cheng Lit, Ylenia Lombardo, Justin Stebbing, Georgios Giamas
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3794.
https://doi.org/10.1158/1538-7445.AM2013-3794
Published: 15 April 2013
View article titled, Abstract 3794: The role of LMTK3 in breast cancer cell growth and invasion.
Journal Articles

Abstract 466: Tumor-induced fibrocytes mediate immune suppression via Indoleamine Oxidase.

Hua Zhang, Crystal L. Mackall
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 466.
https://doi.org/10.1158/1538-7445.AM2013-466
Published: 15 April 2013
View article titled, Abstract 466: Tumor-induced fibrocytes mediate immune suppression via Indoleamine Oxidase.
Journal Articles

Abstract 4316: A dynamic interplay of KSR1, p53 and BRCA1 in breast cancer.

Hua Zhang, Justin Stebbing, Aleksandra Filipovic, Ian O. Ellis, Heinz-Josef Lenz, Georgios Giamas
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4316.
https://doi.org/10.1158/1538-7445.AM2013-4316
Published: 15 April 2013
View article titled, Abstract 4316: A dynamic interplay of KSR1, p53 and BRCA1 in breast cancer.
Journal Articles

Abstract 1291: Tumor growth inhibitory effect in EIF4B silenced in vitro and in vivo lung cancer models

Jung-Young Shin, Xiang-Hua Zhang, Jeong-Oh Kim, Ji-Eun Oh, Hiun Suk Chae, Young Ae Joe, Jin-Hyoung Kang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1291.
https://doi.org/10.1158/1538-7445.AM2012-1291
Published: 15 April 2012
View article titled, Abstract 1291: Tumor growth inhibitory effect in EIF4B silenced in vitro and in vivo lung cancer models
Journal Articles

Abstract 185: Alteration of microRNA expression profiles in HPV-associated squamous cell carcinoma of the head and neck (SCCHN)

Ji-Eun Oh, Jeong-Oh Kim, Jung-Young Shin, Xiang-Hua Zhang, Sang-Hoon Chun, Hye-Sung Won, Chan-Kwon Jung, Sook-Hee Hong, Myoung-Ah Lee, Jin-Hyoung Kang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 185.
https://doi.org/10.1158/1538-7445.AM2012-185
Published: 15 April 2012
View article titled, Abstract 185: Alteration of microRNA expression profiles in HPV-associated squamous cell carcinoma of the head and neck (SCCHN)