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Journal Articles

Abstract CT052: A highly selective, brain-penetrant and overcoming G2032R resistance ROS1 inhibitor JYP0322 in NSCLC patients with ROS1 fusion

Hongyun Zhao, Yanqiu Zhao, Yuxiang Ma, Yan Zhang, Zhangzhou Huang, Ying Cheng, Zhengbo Song, Yongzhong Luo, Juan Li, Wei Wei, Yaling Qi, Binyan Xia, Yuexia Zeng, Jing Lv, Li Zhang

Cancer Res (2025) 85 (8_Supplement_2): CT052.

https://doi.org/10.1158/1538-7445.AM2025-CT052

Published: 25 April 2025

View articletitled, Abstract CT052: A highly selective, brain-penetrant and overcoming G2032R resistance ROS1 inhibitor JYP0322 in NSCLC patients with ROS1 fusion

Journal Articles

Abstract LB027: In vivo delivery of novel CD89 fusion receptor to myeloid cells by mRNA activates anti-tumor immunity

Thomas E. Prod'homme, Shannon Argueta, Hongyun Zhao, Michael Gorgievski, Neha Diwangi, Edward Cochran, Bruce McCreedy, Yuxiao Wang, Daniel Getts

Cancer Res (2023) 83 (8_Supplement): LB027.

https://doi.org/10.1158/1538-7445.AM2023-LB027

Published: 14 April 2023

View articletitled, Abstract LB027: In vivo delivery of novel CD89 fusion receptor to myeloid cells by mRNA activates anti-tumor immunity

Journal Articles

Sustained Aurora Kinase B Expression Confers Resistance to PI3K Inhibition in Head and Neck Squamous Cell Carcinoma

Pooja A. Shah, Vaishnavi Sambandam, Anne M. Fernandez, Hongyun Zhao, Tuhina Mazumdar, Li Shen, Qi Wang, Kazi M. Ahmed, Soma Ghosh, Mitchell J. Frederick, Jing Wang, Faye M. Johnson

Cancer Res (2022) 82 (23): 4444–4456.

https://doi.org/10.1158/0008-5472.CAN-22-1175

Published: 02 December 2022

View articletitled, Sustained Aurora Kinase B Expression Confers Resistance to PI3K Inhibition in Head and Neck Squamous Cell Carcinoma

Includes: Supplementary data

Journal Articles

Abstract LB006: In vivo programming of myeloid cells by mRNA mediated delivery of novel Fc alpha fusion receptor activates anti-tumor immunity

Hongyun Zhao, Inna Shcherbakova, Thomas Prod’homme, Bruce McCreedy, Yuxiao Wang, Daniel Getts

Cancer Res (2022) 82 (12_Supplement): LB006.

https://doi.org/10.1158/1538-7445.AM2022-LB006

Published: 15 June 2022

View articletitled, Abstract LB006: In vivo programming of myeloid cells by mRNA mediated delivery of novel Fc alpha fusion receptor activates anti-tumor immunity

Journal Articles

Abstract CT520: The safety summary of the phase 1a/b trial of QL1706, a novel dual immune checkpoint blockade containing a mixture of anti-PD1 IgG4 and anti-CTLA4 IgG1 antibodies, for advanced malignant tumors

Li Zhang, Hongyun Zhao, Yan Huang, Wenfeng Fang, Yuxiang Ma, Yang Zhang, Xiaoli Wei, Yanhua Yang, Wei Yang, Furong Liu, Zuan Lin, Jianing Li, Qianwen Liu, Benyan Zou, Kunlun Liao, qun Liu

Cancer Res (2022) 82 (12_Supplement): CT520.

https://doi.org/10.1158/1538-7445.AM2022-CT520

Published: 15 June 2022

View articletitled, Abstract CT520: The safety summary of the phase 1a/b trial of QL1706, a novel dual immune checkpoint blockade containing a mixture of anti-PD1 IgG4 and anti-CTLA4 IgG1 antibodies, for advanced malignant tumors

Journal Articles

Abstract 3251: Aurora kinase B expression shields HNSCC from PI3K inhibition-induced apoptosis through downstream mediators AKT and PDK1

Pooja A. Shah, Anne M. Fernandez, Vaishnavi Sambandam, Hongyun Zhao, Tuhina Mazumdar, Li Shen, Jing Wang, Faye M. Johnson

Cancer Res (2022) 82 (12_Supplement): 3251.

https://doi.org/10.1158/1538-7445.AM2022-3251

Published: 15 June 2022

View articletitled, Abstract 3251: Aurora kinase B expression shields HNSCC from PI3K inhibition-induced apoptosis through downstream mediators AKT and PDK1

Journal Articles

Abstract CT119: Development and preliminary clinical activity of QL1706 (PSB205), a combination of anti-PD1 and anti-CTLA-4 antibodies manufactured together as a single product

Li Zhang, Hongyun Zhao, Yuxiang Ma, Yan Huang, Yang Zhang, Xiaoli Wei, Yanhua Yang, Wei Yang, Furong Liu, Zhuan Lin, Jianing Li, Wenfeng Fang, Qianwen Liu, Benyan Zou, Kunlun Liao, Liuqun Liu

Cancer Res (2021) 81 (13_Supplement): CT119.

https://doi.org/10.1158/1538-7445.AM2021-CT119

Published: 01 July 2021

View articletitled, Abstract CT119: Development and preliminary clinical activity of QL1706 (PSB205), a combination of anti-PD1 and anti-CTLA-4 antibodies manufactured together as a single product

Journal Articles

Abstract 707: Combinatorial assessment of ctDNA release and mutational burden predicts clinical outcome from anti-PD-(L)1 therapies in non-small-cell lung cancer

Wenfeng Fang, Yuxiang Ma, Jiani C. Yin, Huaqiang Zhou, Fufeng Wang, Hua Bao, Ao Wang, Xue Wu, Shaodong Hong, Yunpeng Yang, Yan Huang, Hongyun Zhao, Yang W. Shao, Li Zhang

Cancer Res (2020) 80 (16_Supplement): 707.

https://doi.org/10.1158/1538-7445.AM2020-707

Published: 15 August 2020

View articletitled, Abstract 707: Combinatorial assessment of ctDNA release and mutational burden predicts clinical outcome from anti-PD-(L)1 therapies in non-small-cell lung cancer

Journal Articles

Abstract 579: Ensartinib (X-396), a novel ALK TKI, in Chinese ALK-positive non-small cell lung cancer: A phase I, dose-escalation and expansion study

Hongyun Zhao, Yuxiang Ma, Yang Zhang, Shaodong Hong, Wenfeng Fang, Yunpeng Yang, Jianjin Huang, Jing Zhao, Yan Huang, Lieming Ding, Li Mao, Giovanni Selvaggi, Li Zhang

Cancer Res (2020) 80 (16_Supplement): 579.

https://doi.org/10.1158/1538-7445.AM2020-579

Published: 15 August 2020

View articletitled, Abstract 579: Ensartinib (X-396), a novel ALK TKI, in Chinese ALK-positive non-small cell lung cancer: A phase I, dose-escalation and expansion study

Journal Articles

Abstract 439: Metabolic flux analysis reveals targets to sensitize chemoresistance in acute myeloid leukemia induced by mesenchymal stromal cell-derived exosomes

Abhinav Achreja, Hongyun Zhao, Ziwen Zhu, Jonathan Gerszberg, Marina Y. Konopleva, Michael Andreeff, Deepak Nagrath

Cancer Res (2017) 77 (13_Supplement): 439.

https://doi.org/10.1158/1538-7445.AM2017-439

Published: 01 July 2017

View articletitled, Abstract 439: Metabolic flux analysis reveals targets to sensitize chemoresistance in acute myeloid leukemia induced by mesenchymal stromal cell-derived exosomes

Journal Articles

Abstract 4323: Metabolic reprogramming in acute myeloid leukemia cells by mesenchymal stromal cell-derived exosomes induces chemoresistance

Hongyun Zhao, Abhinav Achreja, Ziwen Zhu, Ahmed N. Rawi, Marina Konopleva, Michael Andreeff, Deepak Nagrath

Cancer Res (2017) 77 (13_Supplement): 4323.

https://doi.org/10.1158/1538-7445.AM2017-4323

Published: 01 July 2017

View articletitled, Abstract 4323: Metabolic reprogramming in acute myeloid leukemia cells by mesenchymal stromal cell-derived exosomes induces chemoresistance

Journal Articles

Abstract 5911: Omentin drives metabolic shift in ovarian cancer cells in the omental tumor microenvironment

Chi Lam Au Yeung, Abhinav Achreja, Hongyun Zhao, Tsz-Lun Yeung, Rosemarie Schmandt, Daniel K. Yip, Karen H. Lu, Deepak Nagrath, Samuel C. Mok

Cancer Res (2017) 77 (13_Supplement): 5911.

https://doi.org/10.1158/1538-7445.AM2017-5911

Published: 01 July 2017

View articletitled, Abstract 5911: Omentin drives metabolic shift in ovarian cancer cells in the omental tumor microenvironment

Journal Articles

Abstract 3372: Constraints-based metabolic flux analysis approach links tumor stage to metabolic adaptations and survival in cancer cells

Abhinav Achreja, Lifeng Yang, Hongyun Zhao, Juan Marini, Deepak Nagrath

Cancer Res (2014) 74 (19_Supplement): 3372.

https://doi.org/10.1158/1538-7445.AM2014-3372

Published: 01 October 2014

View articletitled, Abstract 3372: Constraints-based metabolic flux analysis approach links tumor stage to metabolic adaptations and survival in cancer cells

Journal Articles

Abstract 3594: Tumor microenvironment derived exosomes regulate prostate cancer metabolism

Hongyun Zhao, Lifeng Yang, Abhinav Achreja, Juan Marini, Donna Peehl, Deepak Nagrath

Cancer Res (2014) 74 (19_Supplement): 3594.

https://doi.org/10.1158/1538-7445.AM2014-3594

Published: 01 October 2014

View articletitled, Abstract 3594: Tumor microenvironment derived exosomes regulate prostate cancer metabolism

Journal Articles

Abstract 1892: Integrated energetics and flux analysis reveals differential metabolic reprogramming in highly and less invasive cancer cells.

Abhinav Achreja, Lifeng Yang, Hongyun Zhao, Juan C. Marini, Deepak Nagrath

Cancer Res (2013) 73 (8_Supplement): 1892.

https://doi.org/10.1158/1538-7445.AM2013-1892

Published: 15 April 2013

View articletitled, Abstract 1892: Integrated energetics and flux analysis reveals differential metabolic reprogramming in highly and less invasive cancer cells.

Journal Articles

Abstract 5413: Role of NANOG in modulating cancer cell metabolism.

Lifeng Yang, Hongyun Zhao, Juan C. Marini, Collene Jeter, Dean Tang, Deepak Nagrath

Cancer Res (2013) 73 (8_Supplement): 5413.

https://doi.org/10.1158/1538-7445.AM2013-5413

Published: 15 April 2013

View articletitled, Abstract 5413: Role of NANOG in modulating cancer cell metabolism.

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Abstract CT052: A highly selective, brain-penetrant and overcoming G2032R resistance ROS1 inhibitor JYP0322 in NSCLC patients with ROS1 fusion

Abstract LB027: In vivo delivery of novel CD89 fusion receptor to myeloid cells by mRNA activates anti-tumor immunity

Sustained Aurora Kinase B Expression Confers Resistance to PI3K Inhibition in Head and Neck Squamous Cell Carcinoma

Abstract LB006: In vivo programming of myeloid cells by mRNA mediated delivery of novel Fc alpha fusion receptor activates anti-tumor immunity

Abstract CT520: The safety summary of the phase 1a/b trial of QL1706, a novel dual immune checkpoint blockade containing a mixture of anti-PD1 IgG4 and anti-CTLA4 IgG1 antibodies, for advanced malignant tumors

Abstract 3251: Aurora kinase B expression shields HNSCC from PI3K inhibition-induced apoptosis through downstream mediators AKT and PDK1

Abstract CT119: Development and preliminary clinical activity of QL1706 (PSB205), a combination of anti-PD1 and anti-CTLA-4 antibodies manufactured together as a single product

Abstract 707: Combinatorial assessment of ctDNA release and mutational burden predicts clinical outcome from anti-PD-(L)1 therapies in non-small-cell lung cancer

Abstract 579: Ensartinib (X-396), a novel ALK TKI, in Chinese ALK-positive non-small cell lung cancer: A phase I, dose-escalation and expansion study

Abstract 439: Metabolic flux analysis reveals targets to sensitize chemoresistance in acute myeloid leukemia induced by mesenchymal stromal cell-derived exosomes

Abstract 4323: Metabolic reprogramming in acute myeloid leukemia cells by mesenchymal stromal cell-derived exosomes induces chemoresistance

Abstract 5911: Omentin drives metabolic shift in ovarian cancer cells in the omental tumor microenvironment

Abstract 3372: Constraints-based metabolic flux analysis approach links tumor stage to metabolic adaptations and survival in cancer cells

Abstract 3594: Tumor microenvironment derived exosomes regulate prostate cancer metabolism

Abstract 1892: Integrated energetics and flux analysis reveals differential metabolic reprogramming in highly and less invasive cancer cells.

Abstract 5413: Role of NANOG in modulating cancer cell metabolism.

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