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Hong-Gang Wang
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Journal Articles

Abstract LB033: Targeting autophagy in neuroblastoma: Inhibiting VPS34 to enhance anti-GD2 immunotherapy

Jiawen Zhang, Longgui Chen, Yoshinori Takahashi, Hong-Gang Wang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_2): LB033.
https://doi.org/10.1158/1538-7445.AM2025-LB033
Published: 25 April 2025
View articletitled, Abstract LB033: Targeting autophagy in neuroblastoma: Inhibiting VPS34 to enhance anti-GD2 immunotherapy
Journal Articles

Abstract 2623: Targeted therapy with DFMO and immunotherapy equalizes survival in MYCN-amplified neuroblastoma: insights from genomic and network analyses

Anderson O. Cox, Abhinav Nagulapally, Deha Ay, Qianqian Song, Liang Liu, Hong-Gang Wang, Abigail Moore, Valerie I. Brown, Wei Zhang, Giselle L. Saulnier Sholler
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2623.
https://doi.org/10.1158/1538-7445.AM2025-2623
Published: 21 April 2025
View articletitled, Abstract 2623: Targeted therapy with DFMO and immunotherapy equalizes survival in MYCN-amplified neuroblastoma: insights from genomic and network analyses
Journal Articles

Abstract 5994: Neutrophils internalized through LC3-associated phagocytosis trigger tumor ferroptotic cell death in glioblastoma

Tong Y. Lu, Patricia P. Yee, Stephen Y. Chih, Dawit G. Aregawi, Michael J. Glantz, Brad E. Zacharia, Hong-Gang Wang, Wei Li
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5994.
https://doi.org/10.1158/1538-7445.AM2024-5994
Published: 22 March 2024
View articletitled, Abstract 5994: Neutrophils internalized through LC3-associated phagocytosis trigger tumor ferroptotic cell death in glioblastoma
Journal Articles

Abstract 393: RAS and PI3K activation promote glioblastoma progression and ischemia-associated tumor cell death

Soo Yeon Kim, Miaolu Tang, Stephen Chih, Jessica Thorpe, Tong Lu, Hong-Gang Wang, Wei Li
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 393.
https://doi.org/10.1158/1538-7445.AM2024-393
Published: 22 March 2024
View articletitled, Abstract 393: RAS and PI3K activation promote glioblastoma progression and ischemia-associated tumor cell death
Journal Articles

Abstract 2430: The role of cellular iron and the homeostatic iron regulator (HFE) in high-grade brain tumor cell migration

Ganesh Shenoy, Katie Troike, Kondaiah Palsa, Madison Kuhn, Quinn Wade, Becky Slagle-Webb, Amanda Snyder, Chachrit Khunsriraksakul, Justin D. Lathia, Dhimant Desai, Hong-Gang Wang, Elizabeth Proctor, James R. Connor
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2430.
https://doi.org/10.1158/1538-7445.AM2022-2430
Published: 15 June 2022
View articletitled, Abstract 2430: The role of cellular iron and the homeostatic iron regulator (HFE) in high-grade brain tumor cell migration
Journal Articles

Abstract 4216: Tipifarnib inhibits the secretion of tumor-derived small extracellular vesicles and enhances the immunotherapeutic efficacy of dinutuximab in neuroblastoma

Xiaoming Liu, Carson A. Wills, Longgui Chen, Jiawen Zhang, Yuanjun Zhao, Mi Zhou, Jeffrey M. Sundstrom, Todd D. Schell, Vladimir S. Spiegelman, Megan M. Young, Hong-Gang Wang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4216.
https://doi.org/10.1158/1538-7445.AM2022-4216
Published: 15 June 2022
View articletitled, Abstract 4216: Tipifarnib inhibits the secretion of tumor-derived small extracellular vesicles and enhances the immunotherapeutic efficacy of dinutuximab in neuroblastoma
Journal Articles

Chemotherapy-Induced Upregulation of Small Extracellular Vesicle-Associated PTX3 Accelerates Breast Cancer Metastasis

Carson A. Wills, Xiaoming Liu, Longgui Chen, Yuanjun Zhao, Christopher M. Dower, Jeffrey Sundstrom, Hong-Gang Wang
Journal: Cancer Research
Cancer Res (2021) 81 (2): 452–463.
https://doi.org/10.1158/0008-5472.CAN-20-1976
Published: 15 January 2021
View articletitled, Chemotherapy-Induced Upregulation of Small Extracellular Vesicle-Associated PTX3 Accelerates Breast Cancer Metastasis
Open the PDF for Chemotherapy-Induced Upregulation of Small Extracellular Vesicle-Associated PTX3 Accelerates Breast Cancer Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 637: Glucocorticoids act synergistically with FLT3 inhibitors to enhance cell death in FLT3 mutant acute myeloid leukemia

Melat Tsegaye Gebru, Hong-Gang Wang, Jennifer Xavier
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 637.
https://doi.org/10.1158/1538-7445.AM2020-637
Published: 15 August 2020
View articletitled, Abstract 637: Glucocorticoids act synergistically with FLT3 inhibitors to enhance cell death in FLT3 mutant acute myeloid leukemia
Journal Articles

Abstract LB-210: Chemotherapy promotes metastasis through extracellular vesicle secretion

Carson A. Wills, Jeffrey Sundstrom, Hong-Gang Wang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-210.
https://doi.org/10.1158/1538-7445.AM2020-LB-210
Published: 15 August 2020
View articletitled, Abstract LB-210: Chemotherapy promotes metastasis through extracellular vesicle secretion
Journal Articles

Abstract A24: Development of a survivable thoracic neuroblastoma mouse model for the study of the extra-adrenal tumor microenvironment

Christa N. Grant, Lidan Sun, Zhenqiu Liu, Hong-Gang Wang
Journal: Cancer Research
Cancer Res (2020) 80 (11_Supplement): A24.
https://doi.org/10.1158/1538-7445.CAMODELS2020-A24
Published: 02 June 2020
View articletitled, Abstract A24: Development of a survivable thoracic neuroblastoma mouse model for the study of the extra-adrenal tumor microenvironment
Journal Articles

Abstract 1324: TRPM2 promotes leukemia proliferation and survival through modulation of ROS and autophagy

Shu-Jen Chen, Lei Bao, Kerry Keefer, Longgui Chen, JuFang Wang, Xue-Qian Zhang, Santhanam Shanmughapriya, Iwona Hirschler-Laszkiewicz, Muniswamy Madesh, Joseph Y. Cheung, Hong-Gang Wang, Barbara A. Miller
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1324.
https://doi.org/10.1158/1538-7445.AM2018-1324
Published: 01 July 2018
View articletitled, Abstract 1324: TRPM2 promotes leukemia proliferation and survival through modulation of ROS and autophagy
Journal Articles

Abstract 121: Identification and characterization of calcium channel blockers as inhibitors of YAP/TAZ and glioblastoma cells

Wei Li, Zhijun Liu, Jennifer Xavier, Hong-Gang Wang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 121.
https://doi.org/10.1158/1538-7445.AM2017-121
Published: 01 July 2017
View articletitled, Abstract 121: Identification and characterization of calcium channel blockers as inhibitors of YAP/TAZ and glioblastoma cells
Journal Articles

Selective Reversible Inhibition of Autophagy in Hypoxic Breast Cancer Cells Promotes Pulmonary Metastasis

Christopher M. Dower, Neema Bhat, Edward W. Wang, Hong-Gang Wang
Journal: Cancer Research
Cancer Res (2017) 77 (3): 646–657.
https://doi.org/10.1158/0008-5472.CAN-15-3458
Published: 31 January 2017
View articletitled, Selective Reversible Inhibition of Autophagy in Hypoxic Breast Cancer Cells Promotes Pulmonary Metastasis
Open the PDF for Selective Reversible Inhibition of Autophagy in Hypoxic Breast Cancer Cells Promotes Pulmonary Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 323: SKI-178, a single agent co-targeting sphingosine kinase 1 and microtubule dynamics, as a therapeutic strategy for treatment of acute myeloid leukemia

Taryn E. Dick, Jeremy A. Hengst, Laura M. Geffert, Robert F. Paulson, Hong-Gang Wang, David F. Claxton, Mark Kester, Thomas P. Loughran, Jong K. Yun
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 323.
https://doi.org/10.1158/1538-7445.AM2016-323
Published: 15 July 2016
View articletitled, Abstract 323: SKI-178, a single agent co-targeting sphingosine kinase 1 and microtubule dynamics, as a therapeutic strategy for treatment of acute myeloid leukemia
Journal Articles

Abstract 5110: The role of autophagy in the tumor microenvironment

Christopher M. Dower, Hong-Gang Wang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5110.
https://doi.org/10.1158/1538-7445.AM2016-5110
Published: 15 July 2016
View articletitled, Abstract 5110: The role of autophagy in the tumor microenvironment
Journal Articles

Abstract 3527: Inhibition of autophagosome closure promotes iDISC-mediated apoptosis in AML cells

Zhenyuan Tang, Yoshinori Takahashi, Hong-Gang Wang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3527.
https://doi.org/10.1158/1538-7445.AM2016-3527
Published: 15 July 2016
View articletitled, Abstract 3527: Inhibition of autophagosome closure promotes iDISC-mediated apoptosis in AML cells
Journal Articles

Abstract 3531: Autophagy facilitates leukemogenesis in a murine model of MLL-AF9-driven AML

Qiang Liu, Longgui Chen, Hong-Gang Wang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3531.
https://doi.org/10.1158/1538-7445.AM2016-3531
Published: 15 July 2016
View articletitled, Abstract 3531: Autophagy facilitates leukemogenesis in a murine model of MLL-AF9-driven AML
Journal Articles

Abstract 3486: Synergistic effect of quinacrine in combination with decitabine for the treatment of acute myeloid leukemia cells in vitro: implication for treatment of AML in the elderly

Wenge Wang, David T. Dicker, David F. Claxton, Hong-Gang Wang, Wafik S. El-Deiry
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3486.
https://doi.org/10.1158/1538-7445.AM2015-3486
Published: 01 August 2015
View articletitled, Abstract 3486: Synergistic effect of quinacrine in combination with decitabine for the treatment of acute myeloid leukemia cells in vitro: implication for treatment of AML in the elderly
Journal Articles

Abstract 761: Acid ceramidase promotes drug resistance in acute myeloid leukemia through P-gp upregulation mediated by NF- kB activation

Su-Fern Tan, Xin Liu, Kenichiro Doi, Hong-Gang Wang, Myles Cabot, David Feith, Thomas P. Loughran
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 761.
https://doi.org/10.1158/1538-7445.AM2014-761
Published: 01 October 2014
View articletitled, Abstract 761: Acid ceramidase promotes drug resistance in acute myeloid leukemia through P-gp upregulation mediated by NF- kB activation
Journal Articles

Abstract 1805: Characterization of pyoluteorin derivatives as Mcl-1 antagonists

Kenichiro Doi, Krishne Gowda, Qiang Liu, Shen-Shu Sung, Jyh Ming Lin, Shantu Amin, Thomas P. Loughran, Hong-Gang Wang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1805.
https://doi.org/10.1158/1538-7445.AM2014-1805
Published: 01 October 2014
View articletitled, Abstract 1805: Characterization of pyoluteorin derivatives as Mcl-1 antagonists