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Journal Articles

Abstract 3542: Oncolytic adenovirus encoding transgenes for IFN-beta and recombinant CD40 ligand promotes conventional dendritic cell activation and trafficking with enhanced tumor infiltrating lymphocytes for effective cancer immunotherapy

Hong Zheng, Scott Antonia, Mark J. Cantwell, Xiaoqing Yu, Amer A. Beg
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3542.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3542
Published: 15 June 2022
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Abstract 2953: Subtype-specific and structure variation induced 3D genome alteration in acute myeloid leukemia

Jie Xu, Fan Song, Baozhen Zhang, Huijue Lyu, Mikoto Kobayashi, Ziyu Zhao, Ye Hou, Xiaotao Wang, Yu Luan, Bei Jia, Lena Stasiak, Qixuan Wang, Qi Jin, Qiushi Jin, Yihao Fu, Ross C. Hardison, Sinisa Dovat, Leonidas C. Platanias, Yue Yang, Tomoko Yamada, Aaron D. Viny, Ross L. Levine, David F. Claxton, James R. Broach, Hong Zheng, Feng Yue
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2953.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2953
Published: 15 June 2022
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Journal Articles

Abstract GS4-09: Quality of life results from OlympiA: A phase III, multicenter, randomized, placebo-controlled trial of adjuvant olaparib after (neo)-adjuvant chemotherapy in patients with germline BRCA1/2 mutations and high-risk HER-2 negative early breast cancer

Patricia A Ganz, Hanna Bandos, Tanja Spanic, Sue Friedman, Volkmar Müller, Sherko Kümmel, Suzette Delaloge, Etienne Brain, Masakazu Toi, Hideko Yamauchi, Eduardo-Martínez de Dueñas, Anne Armstrong, Seock-Ah Im, Chuangui Song, Hong Zheng, Tomasz Sarosiek, Priyanka Sharma, Giovanna Rossi, Priya Rastogi, Anitra Fielding, Richard D Gelber, Christine Campbell, Judy E Garber, Charles E Geyer, Jr, Andrew NJ Tutt, On behalf of the OlympiA Trial Steering Committeeand Investigators
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): GS4-09.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-GS4-09
Published: 15 February 2022
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Journal Articles

Abstract 697: Defining anti-tumor immune stimulatory mechanisms of MEM-288, a CD40 ligand and IFN-beta dual-transgene armed oncolytic adenovirus

Hong Zheng, Chase D. Powell, Scott Antonia, Mark J. Cantwell, Bradford A. Perez, Amer A. Beg
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 697.
DOI: https://doi.org/10.1158/1538-7445.AM2021-697
Published: 01 July 2021
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Journal Articles

Abstract 4578: Development of MEM-288, a dual-transgene armed and conditionally replication-enhanced oncolytic adenovirus with potent systemic antitumor immunity

Hong Zheng, Wenjie Dai, Scott Antonia, Mark J. Cantwell, Amer A. Beg
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4578.
DOI: https://doi.org/10.1158/1538-7445.AM2020-4578
Published: 15 August 2020
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Journal Articles

Abstract 874: Adoptive transfer of cytotoxic lymphocytes generated by engineered human dendritic cells for AML treatment

Chenchen Zhao, Bei Jia, Yixing Jiang, Hiroko Shike, David F. Claxton, W Christopher Ehmann, Todd D. Schell, Hua Cheng, Bei Liu, Hong Zheng
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 874.
DOI: https://doi.org/10.1158/1538-7445.AM2020-874
Published: 15 August 2020
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Journal Articles

MEK Inhibition Modulates Cytokine Response to Mediate Therapeutic Efficacy in Lung Cancer

Mengyu Xie, Hong Zheng, Ranjna Madan-Lala, Wenjie Dai, Nicholas T. Gimbrone, Zhihua Chen, Fumi Kinose, Sarah A. Blackstone, Keiran S.M. Smalley, W. Douglas Cress, Eric B. Haura, Uwe Rix, Amer A. Beg
Journal: Cancer Research
Cancer Res (2019) 79 (22): 5812–5825.
DOI: https://doi.org/10.1158/0008-5472.CAN-19-0698
Published: 15 November 2019
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Includes: Supplementary data
Journal Articles

Abstract 3558: Interrogation of onco-microRNA 125b reveals androgen receptor as a key upstream transcriptional factor that is targetable in female gastric cancer

Ben Liu, Meng Zhou, Da Yang, Qinghua Wang, Qiang Zhang, Xiangchun Li, Meng Yang, Qiong Wang, Lian Li, Luyang Liu, Hongji Dai, Fengju Song, Hong Zheng, Wei Zhang, Kexin Chen
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3558.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3558
Published: 01 July 2019
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Journal Articles

Eomes+T-betlow CD8+ T Cells Are Functionally Impaired and Are Associated with Poor Clinical Outcome in Patients with Acute Myeloid Leukemia

Bei Jia, Chenchen Zhao, Kevin L. Rakszawski, David F. Claxton, W. Christopher Ehmann, Witold B. Rybka, Shin Mineishi, Ming Wang, Hiroko Shike, Michael G. Bayerl, Jeffrey M. Sivik, Todd D. Schell, Joseph J. Drabick, Raymond J. Hohl, Hong Zheng
Journal: Cancer Research
Cancer Res (2019) 79 (7): 1635–1645.
DOI: https://doi.org/10.1158/0008-5472.CAN-18-3107
Published: 01 April 2019
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Includes: Supplementary data
Journal Articles

Abstract 3405: A mutational signature associated with alcohol consumption and prognostically mutated driver genes in esophageal squamous cell carcinoma

Xiangchun Li, Mengyao Wang, Meng Yang, Hongji Dai, Baifeng Zhang, Wei Wang, Xinlei Chu, Xin Wang, Hong Zheng, Ruifang Niu, Wei Zhang, Kexin Chen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3405.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3405
Published: 01 July 2018
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Journal Articles

Abstract 439: Elucidation of genetic susceptibility in nasopharyngeal carcinoma (NPC) by next-generation sequencing

Wei Dai, Josephine Mun Yee Ko, Bianca Hoi Yan Ng, Hong Zheng, Maria Li Lung
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 439.
DOI: https://doi.org/10.1158/1538-7445.AM2018-439
Published: 01 July 2018
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Journal Articles

Abstract 2472: Benchmark of lncRNA quantification in RNA-Seq of cancer samples

Hong Zheng, Mikel Hernaez, Kevin Brennan, Olivier Gevaert
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2472.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2472
Published: 01 July 2018
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Journal Articles

Abstract 4412: Elevated miR-193a attenuates 5-fluorouricil metabolism enzyme CMPK1, resulting in therapeutic resistance and poor survival in gastric cancer

Hao Chen, Wei Wang, Ben Liu, Lu Han, Xinlei Chu, Hong Zheng, Yanrui Zhao, Xiangchun Li, Lian li, Fengju Song, Wei Zhang, Kexin Chen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4412.
DOI: https://doi.org/10.1158/1538-7445.AM2018-4412
Published: 01 July 2018
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Journal Articles

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220

Panpan Hou, Chao Wu, Yuchen Wang, Rui Qi, Dheeraj Bhavanasi, Zhixiang Zuo, Cedric Dos Santos, Shuliang Chen, Yu Chen, Hong Zheng, Hong Wang, Alexander Perl, Deyin Guo, Jian Huang
Journal: Cancer Research
Cancer Res (2017) 77 (16): 4402–4413.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-1627
Published: 14 August 2017
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Includes: Supplementary data
Journal Articles

Abstract 1709: Targeting immune checkpoint therapy to the lung tumor microenvironment

Allison S. Cohen, Michael L. Doligalski, Hong Zheng, Narges K. Tafreshi, Veronica Estrella, Nella Delva, Jonathan Nguyen, Amer Beg, Mark L. McLaughlin, David L. Morse
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1709.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1709
Published: 01 July 2017
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Journal Articles

Abstract 5407: Integrated analysis of genome-wide microRNA and mRNA profiling reveals unregulated miR-125b associated with poor prognosis by reducing cell apoptosis in gastric cancer

Ben Liu, Da Yang, Fengju Song, Xining Zhang, Yan Guo, Yanrui Zhao, Hong Zheng, Wei Zhang, Kexin Chen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5407.
DOI: https://doi.org/10.1158/1538-7445.AM2017-5407
Published: 01 July 2017
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Journal Articles

Abstract 5662: MEK inhibitors potentiate tumor immune surveillance by enhancing cancer cell response of IFNγ

Mengyu Xie, Hong Zheng, Amer Beg
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5662.
DOI: https://doi.org/10.1158/1538-7445.AM2017-5662
Published: 01 July 2017
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Abstract 125: Whole-exome sequencing identifies NF-kappaB pathway regulators frequently mutated in nasopharyngeal carcinoma

Hong Zheng, Wei Dai, Arthur KL Cheung, Josephine MY Ko, Rebecca Kan, Bonnie WY Wong, Merrin ML Leong, Maria L. Lung
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 125.
DOI: https://doi.org/10.1158/1538-7445.AM2016-125
Published: 15 July 2016
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Abstract 154: Defective calcium signaling pathway highlights the mutational landscapes of liver metastasis from colorectal and breast cancer

Fangfang Song, Xiangchun Li, Yuexin Liu, Hong Zheng, Haixin Li, Jun Wang, Wei Zhang, Kexin Chen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 154.
DOI: https://doi.org/10.1158/1538-7445.AM2016-154
Published: 15 July 2016
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Abstract 4045: Urban-rural disparity of overweight/obesity distribution and its potential association with breast cancer among Chinese females

Ying Gao, Yubei Huang, Hongji Dai, Peishan Wang, Haixin Li, Fengju Song, Hong Zheng, Henglei Dong, Jiali Han, Yaogang Wang, Kexin Chen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4045.
DOI: https://doi.org/10.1158/1538-7445.AM2016-4045
Published: 15 July 2016
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