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Journal Articles

Abstract 2799: SNORD80-guided 2'-O-methylation stabilizes the lncRNA GAS5 to regulate cellular stress responses

Liang Xu, Xiao hong Zhao, Yuan yuan Zhang, Lei Jin, Xu Dong Zhang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2799.
https://doi.org/10.1158/1538-7445.AM2025-2799
Published: 21 April 2025
View articletitled, Abstract 2799: SNORD80-guided 2'-O-methylation stabilizes the lncRNA GAS5 to regulate cellular stress responses
Journal Articles

Abstract 3750: Spatial crosstalk modeling of the tumor microenvironment uncovers CCR5-mediated glia-to-glia signaling as a key regulator of brain metastases

Ju Young Ahn, Jianting Sheng, Xin Wang, Matthew Vasquez, Wenjuan Dong, Hong Zhao, Stephen Wong
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3750.
https://doi.org/10.1158/1538-7445.AM2025-3750
Published: 21 April 2025
View articletitled, Abstract 3750: Spatial crosstalk modeling of the tumor microenvironment uncovers CCR5-mediated glia-to-glia signaling as a key regulator of brain metastases
Journal Articles

Abstract 499: Spatial RNA sequencing supports programmed death ligand 2 (PD-L2) as a potential immunotherapy target in high grade serous ovarian carcinoma (HGSOC)

Elise Yates, Cailin O'Connell, Yin Zheng, Hong Zhao, Aparna Kamat, Biana Godin
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 499.
https://doi.org/10.1158/1538-7445.AM2025-499
Published: 21 April 2025
View articletitled, Abstract 499: Spatial RNA sequencing supports programmed death ligand 2 (PD-L2) as a potential immunotherapy target in high grade serous ovarian carcinoma (HGSOC)
Journal Articles

Abstract 4425: Quantum-inspired computing analysis of spatial omics uncovers immune pathways relevant to T-DXd resistance in metastatic breast cancer

Glori Das, Wenjuan Dong, Matthew Vasquez, Ji-hoon Lee, Yuan Gao, Jenny Chang, Xiaoxian Li, Hong Zhao, Stephen T. Wong
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4425.
https://doi.org/10.1158/1538-7445.AM2025-4425
Published: 21 April 2025
View articletitled, Abstract 4425: Quantum-inspired computing analysis of spatial omics uncovers immune pathways relevant to T-DXd resistance in metastatic breast cancer
Journal Articles

Abstract 6545: Targeting NOS2 and the tumor microenvironment in ovarian cancer: Switching the immune system from “cold” to “hot”

Gianmarco Melone, Ivonne Uzair, Mailin Li, Maria Chervo, Karina Ortega, Jenying Deng, Wei Qian, Jianying Zhou, Liliana Guzman, Kristina Zambo, Harika Nagandla, Hong Zhao, Christoforos Thomas, Fotis Nikolo, Keith Chan, Lewis Francis, Jenny Chang, Aireana Phillips, Xen Ping Hoi
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6545.
https://doi.org/10.1158/1538-7445.AM2025-6545
Published: 21 April 2025
View articletitled, Abstract 6545: Targeting NOS2 and the tumor microenvironment in ovarian cancer: Switching the immune system from “cold” to “hot”
Journal Articles

Abstract C001: Cytomegalovirus infection modulates distinct immune cell dynamics across tumor-immune microenvironments and systemic macroenvironment during metastasis

Wenjuan Dong, Jianting Sheng, Shan Xu, Matthew Vasquez, Hong Zhao, Stephen T.C Wong
Journal: Cancer Research
Cancer Res (2024) 84 (22_Supplement): C001.
https://doi.org/10.1158/1538-7445.TUMBODY-C001
Published: 17 November 2024
View articletitled, Abstract C001: Cytomegalovirus infection modulates distinct immune cell dynamics across tumor-immune microenvironments and systemic macroenvironment during metastasis
Journal Articles

MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer

Si Min Zheng, Yu Chen Feng, Qin Zhu, Ruo Qi Li, Qian Qian Yan, Liu Teng, Yi Meng Yue, Man Man Han, Kaihong Ye, Sheng Nan Zhang, Teng Fei Qi, Cai Xia Tang, Xiao Hong Zhao, Yuan Yuan Zhang, Liang Xu, Ran Xu, Jun Xing, Mark Baker, Tao Liu, Rick F. Thorne, Lei Jin, Thomas Preiss, Xu Dong Zhang, Shundong Cang, Jin Nan Gao
Journal: Cancer Research
Cancer Res (2024) 84 (9): 1460–1474.
https://doi.org/10.1158/0008-5472.CAN-23-3046
Published: 02 May 2024
View articletitled, MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
Open the PDF for MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract PO2-27-07: The Role of HCMV Infection in Facilitating Brain Metastasis through the Creation of a Suppressive Tumor Microenvironment in Breast Cancer Patients

Wenjuan Dong, Xin Wang, Kun Han, Akshjot Puri, Amna Irfan, Wei Qian, Liliana Guzman, Roberto Rosato, Jianting Sheng, Hong Zhao, Jenny Chang, Stephen Wong
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-27-07.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-27-07
Published: 02 May 2024
View articletitled, Abstract PO2-27-07: The Role of HCMV Infection in Facilitating Brain Metastasis through the Creation of a Suppressive Tumor Microenvironment in Breast Cancer Patients
Journal Articles

Abstract PO1-29-04: Spatial tumor microenvironment profiling identifies immune features that correlate with response to T-DXd treatment in patients with metastatic breast cancer

Hong Zhao, Matthew Vasquez, Jeffrey Zhang, Glori Das, Ji-Hoon Lee, Yuan Gao, Jilun Zhang, Xiaoxian Li, Jenny Chang, Stephen Wong
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-29-04.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-29-04
Published: 02 May 2024
View articletitled, Abstract PO1-29-04: Spatial tumor microenvironment profiling identifies immune features that correlate with response to T-DXd treatment in patients with metastatic breast cancer
Journal Articles

Abstract 7052: p53 underpins a dependence on oxidative phosphorylation in glycolysis-competent colorectal cancer

Xiao Hong Zhao, Man Man Han, Qian Qian Yan, Yi Meng Yue, Kai Hong Ye, Yuan Yuan Zhang, Liu Teng, Liang Xu, Xiao Jing Shi, Ting La, Yu Chen Feng, Ran Xu, Vinod K. Narayana, David P. De Souza, Tao Liu, Mark Baker, Rick F. Thorne, Xu Dong Zhang, Song Chen, Lei Jin
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7052.
https://doi.org/10.1158/1538-7445.AM2024-7052
Published: 22 March 2024
View articletitled, Abstract 7052: p53 underpins a dependence on oxidative phosphorylation in glycolysis-competent colorectal cancer
Journal Articles

Abstract 3913: Molecular mechanism of action and targets of glucocorticoids in lymphoma therapy

Jaewoo Choi, Michele Ceribelli, James D. Phelan, Björn Häupl, Da Wei Huang, George W. Wright, Tony Hsiao, Vivian Morris, Francesco Ciccarese, Boya Wang, Sean Corcoran, Sebastian Scheich, Xin Yu, Weihong Xu, Yandan Yang, Hong Zhao, Joyce Zhou, Grace Zhang, Jagan Muppidi, Giorgio Ga Inghirami, Thomas Oellerich, Craig J. Thomas, Wyndham H. Wilson, Louis M. Staudt
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3913.
https://doi.org/10.1158/1538-7445.AM2024-3913
Published: 22 March 2024
View articletitled, Abstract 3913: Molecular mechanism of action and targets of glucocorticoids in lymphoma therapy
Journal Articles

Abstract 6532: Blockade of CD24 sensitizes pancreatic cancer to Kras inhibitors

Yongkun Wei, Minghui Liu, Er-Yen Yen, Jun Yao, Phuoc T. Nguyen, Xiaofei Wang, Zecheng Yang, Abdelrahman Yousef, Dean Pan, Yanqing Jin, Madelaine S. Theady, Jangho Park, Yiming Cai, Mitsunobu Takeda, Matthew Vasquez, Yong Zhou, Hong Zhao, Andrea Viale, Huamin Wang, Dan Zhao, Ronald A. DePinho, Wantong Yao, Haoqiang Ying
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6532.
https://doi.org/10.1158/1538-7445.AM2024-6532
Published: 22 March 2024
View articletitled, Abstract 6532: Blockade of CD24 sensitizes pancreatic cancer to Kras inhibitors
Journal Articles

Abstract CT153: Pemigatinib in Chinese patients with advanced/metastatic or surgically unresectable cholangiocarcinoma Including FGFR2 fusion or rearrangement: Updated overall survival from an open-label, single-arm, multicenter Phase II study

Guoming Shi, Xiaoyong Huang, Tianfu Wen, Tianqiang Song, Ming Kuang, Haibo Mou, Lequn Bao, Haitao Zhao, Hong Zhao, Xielin Feng, Bixiang Zhang, Tao Peng, Yubao Zhang, Xiangcheng Li, Hongsheng Yu, Yu Cao, Yang Luo, Ye Chen, Mingxia Chen, Jia Fan, Jian Zhou
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT153.
https://doi.org/10.1158/1538-7445.AM2023-CT153
Published: 14 April 2023
View articletitled, Abstract CT153: Pemigatinib in Chinese patients with advanced/metastatic or surgically unresectable cholangiocarcinoma Including FGFR2 fusion or rearrangement: Updated overall survival from an open-label, single-arm, multicenter Phase II study
Journal Articles

Abstract 6620: Identification of crosstalk signaling between brain-tumor niche and reactive human cytomegalovirus in brain metastases

Xin Wang, Puri Akshjot, Kun Han, Amna Irfan, Liliana Guzman, Wei Qian, Roberto Rosato, Hong Zhao, Jenny Chang, Stephen Wong
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6620.
https://doi.org/10.1158/1538-7445.AM2023-6620
Published: 04 April 2023
View articletitled, Abstract 6620: Identification of crosstalk signaling between brain-tumor niche and reactive human cytomegalovirus in brain metastases
Journal Articles

Abstract 3798: lncRNA LIMp27 promotes p53-defective cancer pathogenesis

Ting La, Song Chen, Xiao Hong Zhao, Yuan Yuan Zhang, Yu Chen Feng, Xu Dong Zhang, Lei Jin
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3798.
https://doi.org/10.1158/1538-7445.AM2023-3798
Published: 04 April 2023
View articletitled, Abstract 3798: lncRNA LIMp27 promotes p53-defective cancer pathogenesis
Journal Articles

Abstract 3447: NOS inhibition reverses epithelial-to-mesenchymal transition and synergizes with alpelisib in metaplastic breast cancer

Tejaswini P. Reddy, Akshjot Puri, Liliana Guzman-Rojas, Christoforos Thomas, Wei Qian, Jianying Zhou, Hong Zhao, Xiaoxian Li, Bijan Mahboubi, Adrian Oo, Cho Young-Jae, Baek Kim, Jose Thaiparambil, Maria Florencia Chervo, Roberto Rosato, Camila Ayerbe, Noah Giese, Stacy Moulder, Helen Piwnica-Worms, Funda Meric-Bernstam, Jenny C. Chang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3447.
https://doi.org/10.1158/1538-7445.AM2023-3447
Published: 04 April 2023
View articletitled, Abstract 3447: NOS inhibition reverses epithelial-to-mesenchymal transition and synergizes with alpelisib in metaplastic breast cancer
Journal Articles

Abstract PD2-11: Human Cytomegalovirus Reactivation in Immunosuppressive Th2 Tumor Microenvironment Facilitates Brain Metastatic Outgrowth

Xin Wang, Akshjot Puri, Amna Irfan, Kun Han, Wei Qian, Liliana Guzman, Roberto Rosato, Hong Zhao, Jenny Chang, Stephen Wong
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): PD2-11.
https://doi.org/10.1158/1538-7445.SABCS22-PD2-11
Published: 01 March 2023
View articletitled, Abstract PD2-11: Human Cytomegalovirus Reactivation in Immunosuppressive Th2 Tumor Microenvironment Facilitates Brain Metastatic Outgrowth
Journal Articles

Abstract P4-08-05: NOS inhibition reverses epithelial-to-mesenchymal transition and synergizes with alpelisib in metaplastic breast cancer

Tejaswini Reddy, Akshjot Puri, Liliana Guzman, Wei Qian, Jianying Zhou, Roberto Rosato, Hong Zhao, Christoforos Thomas, Xiaoxian Li, Bijan Mahboubi, Adrian Oo, Young-Jae Cho, Baek Kim, Jose Thaiparambil, Camila Ayerbe, Noah Giese, Stacy Moulder, Helen Piwnica-Worms, Funda Meric-Bernstam, Jenny Chang
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P4-08-05.
https://doi.org/10.1158/1538-7445.SABCS22-P4-08-05
Published: 01 March 2023
View articletitled, Abstract P4-08-05: NOS inhibition reverses epithelial-to-mesenchymal transition and synergizes with alpelisib in metaplastic breast cancer
Journal Articles

Abstract P2-07-01: Hydroxytyrosol, a Component of Olive Oil for Breast Cancer Prevention in Women at High Risk

Akshjot Puri, Zheng Yin, Sergio Granados-Principal, Joe Ensor, Liliana Guzman, Roberto Rosato, Hong Zhao, Stephen Wong, Tejal Patel, Jenny Chang
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-07-01.
https://doi.org/10.1158/1538-7445.SABCS22-P2-07-01
Published: 01 March 2023
View articletitled, Abstract P2-07-01: Hydroxytyrosol, a Component of Olive Oil for Breast Cancer Prevention in Women at High Risk
Journal Articles

Abstract 633: Delineating tumor-neural communication in brain metastasis with spatiotemporal transcriptomic analysis and multi-cellular crosstalk modeling

Xin Wang, Ying Zhu, Jianting Sheng, Hong Zhao, Stephen Wong
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 633.
https://doi.org/10.1158/1538-7445.AM2022-633
Published: 15 June 2022
View articletitled, Abstract 633: Delineating tumor-neural communication in brain metastasis with spatiotemporal transcriptomic analysis and multi-cellular crosstalk modeling