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Journal Articles

Extracellular Vesicle-Packaged ACSL4 Induces Hepatocyte Senescence to Promote Hepatocellular Carcinoma Progression

Pei-pei Hou, Chong-ming Zheng, Si-hong Wu, Xi-xiao Liu, Guang-xin Xiang, Wei-yang Cai, Gang Chen, Yong-liang Lou
Journal: Cancer Research
Cancer Res (2024)
https://doi.org/10.1158/0008-5472.CAN-24-0832
Published: 03 September 2024
View article titled, Extracellular Vesicle-Packaged ACSL4 Induces Hepatocyte Senescence to Promote Hepatocellular Carcinoma Progression
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Includes: Supplementary data
Journal Articles

Intratumoral Microbiota Composition Regulates Chemoimmunotherapy Response in Esophageal Squamous Cell Carcinoma

Hong Wu, Xuefeng Leng, Qianshi Liu, Tianqin Mao, Tao Jiang, Yiqiang Liu, Feifei Li, Chenhui Cao, Jun Fan, Liang Chen, Yaqi Chen, Quan Yao, Shun Lu, Renchuan Liang, Lanlin Hu, Mingxin Liu, Yejian Wan, Zhaoshen Li, Jun Peng, Qiyu Luo, Hang Zhou, Jun Yin, Ke Xu, Mei Lan, Xinhao Peng, Haitao Lan, Gang Li, Yongtao Han, Xia Zhang, Zhi-Xiong Jim Xiao, Jinyi Lang, Guihua Wang, Chuan Xu
Journal: Cancer Research
Cancer Res (2023) 83 (18): 3131–3144.
https://doi.org/10.1158/0008-5472.CAN-22-2593
Published: 15 September 2023
View article titled, Intratumoral Microbiota Composition Regulates Chemoimmunotherapy Response in Esophageal Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Abstract 4918: Natural compounds ursolic acid and digoxin exhibit anti-cancer effects through nuclear receptor RORγ-dependent and -independent mechanisms

Hongye Zou, Yatian Yang, Demin Cai, Hong-Wu Chen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4918.
https://doi.org/10.1158/1538-7445.AM2023-4918
Published: 04 April 2023
View article titled, Abstract 4918: Natural compounds ursolic acid and digoxin exhibit anti-cancer effects through nuclear receptor RORγ-dependent and -independent mechanisms
Journal Articles

Abstract 3862: IGFBP3 promotes resistance to olaparib via modulating EGFR signaling in advanced prostate cancer

Amy R. Leslie, Shu Ning, Leandro S. D'Abronzo, Cameron Armstrong, Masuda Sharifi, Zachary A. Schaaf, Wei Lou, Christopher P. Evans, Hong-Wu Chen, Alan Lombard, Allen C. Gao
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3862.
https://doi.org/10.1158/1538-7445.AM2023-3862
Published: 04 April 2023
View article titled, Abstract 3862: IGFBP3 promotes resistance to olaparib via modulating EGFR signaling in advanced prostate cancer
Journal Articles

Abstract 721: Epigenetic intervention in the prevention of Lynch Syndrome Colorectal Cancer

Laura Reyes Uribe, Charles M Bowen, Kyera Evans, Hong Wu, Fahriye Duzagac, Krishna Sinha, Eduardo Vilar
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 721.
https://doi.org/10.1158/1538-7445.AM2022-721
Published: 15 June 2022
View article titled, Abstract 721: Epigenetic intervention in the prevention of Lynch Syndrome Colorectal Cancer
Journal Articles

Abstract 2882: Coronin 1B overexpression promotes invasion of HPV- HNSCC

Jessica L. Allen, Elyse L. Walk, Kristen L. Rhodes, Steven M. Markwell, Brenen W. Papenberg, Hong Wu, Marileila Garcia, James E. Bear, Scott A. Weed
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2882.
https://doi.org/10.1158/1538-7445.AM2021-2882
Published: 01 July 2021
View article titled, Abstract 2882: Coronin 1B overexpression promotes invasion of HPV- HNSCC
Journal Articles

The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells

Prashant V. Bommi, Charles M. Bowen, Laura Reyes-Uribe, Wenhui Wu, Hiroyuki Katayama, Pedro Rocha, Edwin R. Parra, Alejandro Francisco-Cruz, Zuhal Ozcan, Elena Tosti, Jason A. Willis, Hong Wu, Melissa W. Taggart, Jared K. Burks, Patrick M. Lynch, Winfried Edelmann, Paul A. Scheet, Ignacio I. Wistuba, Krishna M. Sinha, Samir M. Hanash, Eduardo Vilar
Journal: Cancer Research
Cancer Res (2021) 81 (10): 2760–2773.
https://doi.org/10.1158/0008-5472.CAN-20-2896
Published: 15 May 2021
View article titled, The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells
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Includes: Supplementary data
Journal Articles

Abstract 2932: CD59 facilitates tumor progression through activating TGF-β/Smad signaling pathway in hepatocellular carcinoma

Tian Lan, Hong Wu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2932.
https://doi.org/10.1158/1538-7445.AM2020-2932
Published: 15 August 2020
View article titled, Abstract 2932: CD59 facilitates tumor progression through activating TGF-β/Smad signaling pathway in hepatocellular carcinoma
Journal Articles

Abstract P5-03-11: Germline and somatic variants in patients with inflammatory breast cancer (IBC) detected using cell-free DNA

Jennifer S. Winn, Zachary Hasse, Jianming Pei, Michael Slifker, Sebastian M. Arisi-Fernandez, Jacqueline N. Talarchek, Elias Obeid, Karthik Devarajan, Hong Wu, Yulan Gong, Massimo Cristofanilli, R.Katherine Alpaugh, Sandra Viviana Fernandez
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-03-11.
https://doi.org/10.1158/1538-7445.SABCS19-P5-03-11
Published: 15 February 2020
View article titled, Abstract P5-03-11: Germline and somatic variants in patients with inflammatory breast cancer (IBC) detected using cell-free DNA
Journal Articles

LncRNA SNHG10 Facilitates Hepatocarcinogenesis and Metastasis by Modulating Its Homolog SCARNA13 via a Positive Feedback Loop

Tian Lan, Kefei Yuan, Xiaokai Yan, Lin Xu, Haotian Liao, Xiangyong Hao, Jinju Wang, Hong Liu, Xiangzheng Chen, Kunlin Xie, Jiaxin Li, Mingheng Liao, Jiwei Huang, Yong Zeng, Hong Wu
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (13): 3220–3234.
https://doi.org/10.1158/0008-5472.CAN-18-4044
Published: 01 July 2019
View article titled, LncRNA SNHG10 Facilitates Hepatocarcinogenesis and Metastasis by Modulating Its Homolog SCARNA13 via a Positive Feedback Loop
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Includes: Supplementary data
Journal Articles

Abstract 334: Proteostasis by HSP70/STUB1 complex regulates androgen receptor variants expression and confers resistance to enzalutamide and abiraterone

Chengfei Liu, Wei Lou, Joy C. Yang, Liangren Liu, Cameron M. Armstrong, Alan P. Lombard, Ruining Zhao, Onika DV Noel, Clifford G. Tepper, Hong-Wu Chen, Marc Dall’Era, Marc Dall’Era, Christopher P. Evans, Allen C. Gao
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 334.
https://doi.org/10.1158/1538-7445.AM2019-334
Published: 01 July 2019
View article titled, Abstract 334: Proteostasis by HSP70/STUB1 complex regulates androgen receptor variants expression and confers resistance to enzalutamide and abiraterone
Journal Articles

ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma

Abibatou Ndoye, Anna Budina-Kolomets, Curtis H. Kugel, III, Marie R. Webster, Amanpreet Kaur, Reeti Behera, Vito W. Rebecca, Ling Li, Patricia A. Brafford, Qin Liu, Y.N. Vashisht Gopal, Michael A. Davies, Gordon B. Mills, Xiaowei Xu, Hong Wu, Meenhard Herlyn, Michael C. Nicastri, Jeffrey D. Winkler, Maria S. Soengas, Ravi K. Amaravadi, Maureen E. Murphy, Ashani T. Weeraratna
Journal: Cancer Research
Cancer Res (2017) 77 (21): 5873–5885.
https://doi.org/10.1158/0008-5472.CAN-17-0907
Published: 31 October 2017
View article titled, ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma
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Includes: Supplementary data
Journal Articles

Abstract LB-226: Dual inhibition of CD47 and HER2 to radiosensitize breast cancer cells

Demet Candas, Lu Zhang, Cheikh Menaa, Ming Fan, Yanhong Zhang, Lin Liu, Weibing Zhou, Soheila Azghadi, Colleen Sweeney, Rulong Shen, Tzu-yin Lin, Chong-xian Pan, Andrew T. Vaughan, Ji Ming Wang, Hong-Wu Chen, Kit Lam, Lun-Quan Sun, Arta M. Monjazeb, William J. Murphy, Jian Jian Li
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-226.
https://doi.org/10.1158/1538-7445.AM2017-LB-226
Published: 01 July 2017
View article titled, Abstract LB-226: Dual inhibition of CD47 and HER2 to radiosensitize breast cancer cells
Journal Articles

Abstract B08: ER chaperone GRP78 increases chemoresistance in pancreatic ductal adenocarcinoma

Jenifer B. Gifford, Wei Huang, Ann E. Zeleniak, Antreas Hindoyan, Hong Wu, Timothy R. Donahue, Reginald Hill
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B08.
https://doi.org/10.1158/1538-7445.PANCA16-B08
Published: 14 December 2016
View article titled, Abstract B08: ER chaperone GRP78 increases chemoresistance in pancreatic ductal adenocarcinoma
Journal Articles

Abstract B36: Preclinical development of a multikinase targeting molecule with activity against the cancer stem cell phenotype in pancreatic adenocarcinoma

Taylor Aiken, Yansong Bian, Yaroslav Teper, Lesley Mathews Griner, Rajarshi Guha, Paul Shinn, Hong-Wu Xin, Holger Pflicke, Jian-kang Jiang, Paresma Patel, Steven Rogers, Jeffery Aube, Marc Ferrer, Craig J. Thomas, Udo Rudloff
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B36.
https://doi.org/10.1158/1538-7445.PANCA16-B36
Published: 14 December 2016
View article titled, Abstract B36: Preclinical development of a multikinase targeting molecule with activity against the cancer stem cell phenotype in pancreatic adenocarcinoma
Journal Articles

Abstract 3062: Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy

Junjian Wang, Haibin Wang, Lingyu Wang, Demin Cai, Zhijian Duan, Peng Chen, June X Zou, Jianzhen Xu, Xinbin Chen, Hsing-Jien Kung, Hong-wu Chen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3062.
https://doi.org/10.1158/1538-7445.AM2016-3062
Published: 15 July 2016
View article titled, Abstract 3062: Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy
Journal Articles

Abstract 5064: CORO1B amplification and expression status identifies an aggressive subset of chromosome 11q13 amplified HNSCC

Jessica L. Allen, Elyse L. Walk, Kristen L. Rhodes, Colleen J. Beatty, Steven M. Markwell, Brenen W. Papenberg, Erik T. Interval, Hong Wu, Marileila Varella Garcia, James E. Bear, Scott A. Weed
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5064.
https://doi.org/10.1158/1538-7445.AM2016-5064
Published: 15 July 2016
View article titled, Abstract 5064: CORO1B amplification and expression status identifies an aggressive subset of chromosome 11q13 amplified HNSCC
Journal Articles

HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors

Anna Budina-Kolomets, Marie R. Webster, Julia I-Ju Leu, Matthew Jennis, Clemens Krepler, Anastasia Guerrini, Andrew V. Kossenkov, Wei Xu, Giorgos Karakousis, Lynn Schuchter, Ravi K. Amaravadi, Hong Wu, Xiangfan Yin, Qin Liu, Yiling Lu, Gordon B. Mills, Xiaowei Xu, Donna L. George, Ashani T. Weeraratna, Maureen E. Murphy
Journal: Cancer Research
Cancer Res (2016) 76 (9): 2720–2730.
https://doi.org/10.1158/0008-5472.CAN-15-2137
Published: 01 May 2016
View article titled, HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors
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Includes: Supplementary data
Journal Articles

Abstract 4806: Characterizing the genomic landscape of premalignant colorectal polyps using next-generation sequencing

Ester Borras, Anthony San Lucas, Kyle Chang, Gita Bhatia, Hong Wu, Jerry Fowler, Y. Nancy You, Patrick M. Lynch, Melissa W. Taggart, Ernest T. Hawk, Gabriel Capella, Paul Scheet, Eduardo Vilar
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4806.
https://doi.org/10.1158/1538-7445.AM2015-4806
Published: 01 August 2015
View article titled, Abstract 4806: Characterizing the genomic landscape of premalignant colorectal polyps using next-generation sequencing
Journal Articles

Tracking and Functional Characterization of Epithelial–Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis

Marcus Ruscetti, Bill Quach, Eman L. Dadashian, David J. Mulholland, Hong Wu
Journal: Cancer Research
Cancer Res (2015) 75 (13): 2749–2759.
https://doi.org/10.1158/0008-5472.CAN-14-3476
Published: 30 June 2015
View article titled, Tracking and Functional Characterization of Epithelial–Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis
Open the PDF for Tracking and Functional Characterization of Epithelial–Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis in another window
Includes: Supplementary data