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Journal Articles

Abstract PO5-04-07: Characteristics of patients with metastatic HR+/HER2+ breast cancer in a Kaiser Permanente observational multi-site cohort

Sheila Weinmann, Debra Ritzwoller, Marilyn Kwan, Reina Haque, Stella Stergiopoulos, Ashley Cha, Eric Gauthier, Daniel Sapp, John Dickerson, Kathryn Richert-Boe, Weiming Hu, Nikki Carroll, Lie Hong Chen, Valerie Lee, Ravi Zalavadia, Maureen O'Keeffe-Rosetti
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-04-07.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-04-07
Published: 02 May 2024
View article titled, Abstract PO5-04-07: Characteristics of patients with metastatic HR+/HER2+ breast cancer in a Kaiser Permanente observational multi-site cohort
Journal Articles

Abstract 3761: A modified SELEX enables the efficient identification of DNA aptamers with potential for specific cancer targeting

Yang Lin, Cho-Yi Chen, Zhi-Qian Lin, Bing-Hong Chen, Yi-Chen Sun, Kai-Feng Hung
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3761.
https://doi.org/10.1158/1538-7445.AM2024-3761
Published: 22 March 2024
View article titled, Abstract 3761: A modified SELEX enables the efficient identification of DNA aptamers with potential for specific cancer targeting
Journal Articles

Abstract 2194: Association of metabolic syndrome conditions with risk of second primary cancer of any organ in breast cancer survivors

Amrita Mukherjee, Zheng Gu, Lie Hong Chen, Arnold L. Potosky, Reina Haque
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2194.
https://doi.org/10.1158/1538-7445.AM2024-2194
Published: 22 March 2024
View article titled, Abstract 2194: Association of metabolic syndrome conditions with risk of second primary cancer of any organ in breast cancer survivors
Journal Articles

Abstract 4835: Demographic factors and risk of persistent opioid use in a diverse cohort of breast cancer survivors

Lie Hong Chen, Rulin C. Hechter, Jiaxiao Shi, Zheng Gu, Moira Brady-Rogers, Rowan T. Chlebowski, Reina Haque
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4835.
https://doi.org/10.1158/1538-7445.AM2024-4835
Published: 22 March 2024
View article titled, Abstract 4835: Demographic factors and risk of persistent opioid use in a diverse cohort of breast cancer survivors
Journal Articles

Abstract 3387: Spatial analysis revealed distinct molecular and immune landscape in genetic versus carcinogen-induced lung adenocarcinoma precancer mouse models

Bo Zhu, Pingjun Chen, Jian-Rong Li, Muhammad Aminu, Chenyang Li, Hong Chen, Yanhua Tian, Frank R. Rojas, Parra Cuentas Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Shawna M. Hubert, Khaja B. Khan, Wei Lu, Xingzhi Song, Jianhua Zhang, Don L. Gibbons, Luisa M. Solis Soto, Ignacio I. Wistuba, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3387.
https://doi.org/10.1158/1538-7445.AM2024-3387
Published: 22 March 2024
View article titled, Abstract 3387: Spatial analysis revealed distinct molecular and immune landscape in genetic versus carcinogen-induced lung adenocarcinoma precancer mouse models
Journal Articles

Abstract 3379: Single-cell profiling reveals dynamic epithelial and immune cell interactions in the progression of lung adenocarcinoma

Hong Chen, Bo Zhu, Junya Fujimoto, Yanhua Tian, Jian-Rong Li, Chenyang Li, Pingjun Chen, Alexandre Reuben, Monique Nilsson, Xiuning Le, Alissa Poteete, Shawna M. Hubert, Don L. Gibbons, Ignacio I. Wistuba, Jia Wu, Chao Cheng, John V. Heymach, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3379.
https://doi.org/10.1158/1538-7445.AM2024-3379
Published: 22 March 2024
View article titled, Abstract 3379: Single-cell profiling reveals dynamic epithelial and immune cell interactions in the progression of lung adenocarcinoma
Journal Articles

Abstract 1502: Deciphering the spatial and temporal dynamics of premetastatic niche in lung mediated by Treg and myeloid cell interactions

Yanhua Tian, Jian-Rong Li, Bo Zhu, Jared Fradette, Hong Chen, Chenyang Li, Leticia Rodriguez, Daniel Kraushaar, Luisa Solis, Alexandre Reuben, Ignacio Wistuba, Don L. Gibbons, Chao Cheng, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1502.
https://doi.org/10.1158/1538-7445.AM2024-1502
Published: 22 March 2024
View article titled, Abstract 1502: Deciphering the spatial and temporal dynamics of premetastatic niche in lung mediated by Treg and myeloid cell interactions
Journal Articles

Abstract 6098: Spatial single-cell immune microenvironment analysis reveals the transition from innate to adaptive immune response during early lung adenocarcinoma carcinogenesis

Bo Zhu, Pingjun Chen, Muhammad Aminu, Junya Fujimoto, Lingzhi Hong, Andre L. Moreira, Jian-Rong Li, Yanhua Tian, Luisa M. Solis Soto, Parra Cuentas Edwin Roger, Ou Shi, Hong Chen, Frank R. Rojas, Eduardo Vilar, Anirban Maitra, Ken Chen, Nicolas Navin, Cara L. Haymacker, Vamsidhar Velcheti, Daniel H. Sterman, P Andrew Futreal, Don L. Gibbons, Ignacio I. Wistuba, John V. Heymach, Chao Cheng, Harvey I. Pass, Jia Wu, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6098.
https://doi.org/10.1158/1538-7445.AM2024-6098
Published: 22 March 2024
View article titled, Abstract 6098: Spatial single-cell immune microenvironment analysis reveals the transition from innate to adaptive immune response during early lung adenocarcinoma carcinogenesis
Journal Articles

Osimertinib Covalently Binds to CD34 and Eliminates Myeloid Leukemia Stem/Progenitor Cells

Li Xia, Jie-Yang Liu, Meng-Ying Yang, Xue-Hong Zhang, Yue Jiang, Qian-Qian Yin, Chen-Hui Luo, Hong-Chen Liu, Zhi-Jie Kang, Cheng-Tao Zhang, Bei-Bei Gao, Ai-Wu Zhou, Hai-Yan Cai, Edmund K. Waller, Jin-Song Yan, Ying Lu
Journal: Cancer Research
Cancer Res (2024) 84 (3): 479–492.
https://doi.org/10.1158/0008-5472.CAN-23-1632
Published: 01 February 2024
View article titled, Osimertinib Covalently Binds to CD34 and Eliminates Myeloid Leukemia Stem/Progenitor Cells
Open the PDF for Osimertinib Covalently Binds to CD34 and Eliminates Myeloid Leukemia Stem/Progenitor Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 495: Discovery of BPI-221351, a potent, selective, orally available, and brain penetrating dual inhibitor of mutant IDH1/2

Hongling Shen, Xiaofeng Xu, Yabin Li, Xizhen Song, Jie Chen, Yunting Bi, Jing Guo, Tong Xu, Huijuan Zhang, Lijia Liu, Zhengyao Zou, Jialin Ren, Jun Tong, Xiaoyun Liu, Hongfei Rong, Teng Ma, Chao Wang, Xiangyong Liu, Hong Chen, Jiayu Zhao, Xuepeng Ju, Haibo Chen, Haidi Shen, Hong Lan, Lieming Ding, Jiabing Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 495.
https://doi.org/10.1158/1538-7445.AM2023-495
Published: 04 April 2023
View article titled, Abstract 495: Discovery of BPI-221351, a potent, selective, orally available, and brain penetrating dual inhibitor of mutant IDH1/2
Journal Articles

Abstract 6513: Single cell and spatial profiling reveal molecular and immune evolution from precancers to invasive lung adenocarcinomas in genetic and carcinogen-induced mouse models

Bo Zhu, Jian-Rong Li, Hong Chen, Pingjun Chen, Junya Fujimoto, Yanhua Tian, Muhammad Aminu, Chenyang Li, Lingzhi Hong, Alexandre Reuben, Edwin Roger Parra Cuentas, Ou Shi, Monique Nilsson, Alissa Poteete, Shawna Hubert, Khaja Khan, Wei Lu, Daniel Kraushaar, Xingzhi Song, Jianhua Zhang, Don Gibbons, Luisa Solis Soto, Ignacio Wistuba, Jia Wu, John Heymach, Chao Cheng, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6513.
https://doi.org/10.1158/1538-7445.AM2023-6513
Published: 04 April 2023
View article titled, Abstract 6513: Single cell and spatial profiling reveal molecular and immune evolution from precancers to invasive lung adenocarcinomas in genetic and carcinogen-induced mouse models
Journal Articles

Abstract 501: Discovery of BPI-460372, a potent and selective inhibitor of TEAD for the treatment of solid tumors harboring Hippo pathway aberrations

Hongling Shen, Xiaofeng Xu, Hongfei Rong, Xizhen Song, Jinheng Gao, Jie Chen, Di Zhu, Xiangdong Zhao, Jun Tong, Zhengyao Zou, Xiaoyun Liu, Jin Guo, Yan Xu, Yabin Li, Xiangyong Liu, Hong Chen, Jiayu Zhao, Yanju Liu, Xuepeng Ju, Haibo Chen, Hong Lan, Lieming Ding, Jiabing Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 501.
https://doi.org/10.1158/1538-7445.AM2023-501
Published: 04 April 2023
View article titled, Abstract 501: Discovery of BPI-460372, a potent and selective inhibitor of TEAD for the treatment of solid tumors harboring Hippo pathway aberrations
Journal Articles

Abstract 3753: miR-567 modulates the progression of melanoma cells and functions of macrophages

Mai-Huong Thi Nguyen, Chen-Huan Lin, Yu-Chi Huang, Mu-Shiun Tsai, Ming-Hong Chen, Azusa Miyashita, Satoshi Fukushima, Nianhan Ma
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3753.
https://doi.org/10.1158/1538-7445.AM2023-3753
Published: 04 April 2023
View article titled, Abstract 3753: miR-567 modulates the progression of melanoma cells and functions of macrophages
Journal Articles

Abstract 1300: Single-cell and spatial transcriptomic profiling reveal the cascade of immune events during progression and metastasis of non-small cell lung cancer

Yanhua Tian, Jian-Rong Li, Bo Zhu, Jared Fradette, Hong Chen, Chenyang Li, Sijia Cui, Daniel Kraushaar, Junya Fujimoto, Leticia Rodriguez, Luisa Maren Solis Soto, Alexandre Reuben, Ignacio Wistuba, Don Gibbons, Cheng Chao, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1300.
https://doi.org/10.1158/1538-7445.AM2023-1300
Published: 04 April 2023
View article titled, Abstract 1300: Single-cell and spatial transcriptomic profiling reveal the cascade of immune events during progression and metastasis of non-small cell lung cancer
Journal Articles

Abstract 6524: Single-cell transcriptomic analysis reveals immune landscape in the malignant transformation of normal lung to lung adenocarcinoma in genetic murine models

Hong Chen, Bo Zhu, Junya Fujimoto, Yanhua Tian, Jian-Rong Li, Pingjun Chen, Alexandre Reuben, Monique B. Nilsson, Xiuning Le, Alissa Poteete, Shawna M. Hubert, Don L. Gibbons, Ignacio I. Wistuba, Jia Wu, Chao Cheng, John V. Heymach, Jianjun Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6524.
https://doi.org/10.1158/1538-7445.AM2023-6524
Published: 04 April 2023
View article titled, Abstract 6524: Single-cell transcriptomic analysis reveals immune landscape in the malignant transformation of normal lung to lung adenocarcinoma in genetic murine models
Journal Articles

Abstract P3-03-15: Physical Activity and Risk of Death in Breast Cancer Survivors: A Prospective Study

Lie Hong Chen, Michael R. Irwin, Richard Olmstead, Reina Haque
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P3-03-15.
https://doi.org/10.1158/1538-7445.SABCS22-P3-03-15
Published: 01 March 2023
View article titled, Abstract P3-03-15: Physical Activity and Risk of Death in Breast Cancer Survivors: A Prospective Study
Journal Articles

Abstract 2580: Infiltration and spatial distribution of immune cells are associated clinical benefit from Nivolumab and Ipilimumab for previously treated patients with stage IV squamous cell lung cancer: an immune biomarker analysis of Phase III SWOG LungMAP S1400I trial

Edwin Roger Parra, Jiexin Zhang, Mary Redman, Rossana Lazcano, Piubelli Mario, Caddie Laberiano Fernandez, Renganayaki K. Krishna, Shanyu Zhang, Hong Chen, Ganiraju Manyam, Radim Moravec, Ethan Cerami, James Lindsay, Joyce Yu, Roshni Biswas, Stephen Van Nostrand, Dzifa Y. Duose, Jianjun Zhang, Roy Herbst, Gheath Al-Atrash, Kasthuri Kannan, Ignacio I. Wistuba, Scott Gettinger, Lyudmila Bazhenova, Jack Lee, Jianhua Zhang, Cara Haymaker
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2580.
https://doi.org/10.1158/1538-7445.AM2022-2580
Published: 15 June 2022
View article titled, Abstract 2580: Infiltration and spatial distribution of immune cells are associated clinical benefit from Nivolumab and Ipilimumab for previously treated patients with stage IV squamous cell lung cancer: an immune biomarker analysis of Phase III SWOG LungMAP S1400I trial
Journal Articles

Abstract 5444: BPI-371153, an orally bioavailable small molecule PD-L1 inhibitor

Yiqian Wang, Xiangyan Jing, Hong Chen, Huijuan Zhang, Tianyi Ma, Yao Zhang, Chunhui Zhang, Guangzhi Zhang, Xiangyong Liu, Dan Yan, Jing Guo, Hong Lan, Jiabing Wang, Lieming Ding
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5444.
https://doi.org/10.1158/1538-7445.AM2022-5444
Published: 15 June 2022
View article titled, Abstract 5444: BPI-371153, an orally bioavailable small molecule PD-L1 inhibitor
Journal Articles

Abstract 1994: Pre-existence of poly-resistant cancer stem cells in high-grade ovarian cancer

Wa Xian, Frank McKeon, Christopher Crum, Jingzhong Xie, Bailiang Wang, Yusuke Yamamoto, Suzy Torti, Molly Brewer, Matthew Anderson, Amir Jazaeri, Giulio Draetta, Shan Wang, Rajasekaran Mahalingam, Hong Chen, Marcin Duleba, Wei Rao
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1994.
https://doi.org/10.1158/1538-7445.AM2018-1994
Published: 01 July 2018
View article titled, Abstract 1994: Pre-existence of poly-resistant cancer stem cells in high-grade ovarian cancer
Journal Articles

Abstract 5775: Identification of SAR439859, an orally bioavailable selective estrogen receptor degrader (SERD) that has strong anti-tumor activity in wild-type and mutant ER+ breast cancer models

Maysoun Shomali, Youssef El-Ahmad, Frank Halley, Jane Cheng, Michael Weinstein, Muchun Wang, Fangxian Sun, Natalia Malkova, Mikhail Levit, Malvika Koundinya, Zhuyan Gou, Andrew Hebert, Jessica McManus, Dietmar Hoffman, Hui Cao, Joonil Jung, Jack Pollard, Sylvie Vincent, Timothy Ackerson, Francisco Adrian, Chris Winter, Victoria Richon, Hong Chen, Karl Hsu, Joanne Lager, Albane Courjaud, Rosalia Arrebola, Laurent Besret, Pierre-Yves Abecassis, Laurent Schio, Gary McCort, Michel Tabart, Victor Certal, Fabienne Thompson, Bruno Filoche-Rommé, Laurent Debussche, Patrick Cohen, Carlos Garcia-Echeverria, Monsif Bouaboula
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5775.
https://doi.org/10.1158/1538-7445.AM2018-5775
Published: 01 July 2018
View article titled, Abstract 5775: Identification of SAR439859, an orally bioavailable selective estrogen receptor degrader (SERD) that has strong anti-tumor activity in wild-type and mutant ER+ breast cancer models