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Journal Articles

Ralph A. Reisfeld, PhD: In Memoriam (1926–2020)

James P. Allison, Edward Barker, Jürgen C. Becker, Thomas F. Bumol, David Cheresh, Bill Church, Soldano Ferrone, Darrell R. Galloway, Martin Giedlin, Stephen Gillies, Rupert Handgretinger, John R. Harper, Kohzoh Imai, Barry Kahan, Ruth Ladenstein, Debbie Liao, Holger N. Lode, Hans Loibner, Yun-Ping Luo, Barbara M. Mueller, AhKau Ng, Andreas Niethammer, Michele Pellegrino, Ursula Pertl, Vito Quaranta, Carlo Russo, Helen Sabzevari, Martin Schrappe, Gregor Schulz, Paul Sondel, Andreas Stahl, Argyrios Theophilopoulos, Nissi Varki, Leslie Walker, Barry Wilson, Wolfgang Wrasidlo, Ursula Wargalla-Plate, Rong Xiang, Alice Yu, He Zhou
Journal: Cancer Research
Cancer Res (2021) 81 (6): 1429–1430.
https://doi.org/10.1158/0008-5472.CAN-21-0450
Published: 15 March 2021
View article titled, Ralph A. Reisfeld, PhD: In Memoriam (1926–2020)
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Journal Articles

Abstract 2808: GD2-specific genetically engineered NK cell therapy is effective in a drug-resistant neuroblastoma xenograft mouse model

Diana Seidel, Anastasia Shibina, C. Patrick Reynolds, Winfried S. Wels, Nicole Huebener, Holger N. Lode
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2808.
https://doi.org/10.1158/1538-7445.AM2014-2808
Published: 01 October 2014
View article titled, Abstract 2808: GD2-specific genetically engineered NK cell therapy is effective in a drug-resistant neuroblastoma xenograft mouse model
Journal Articles

Abstract A28: Generation and characterization of anti-idiotype antibody ganglidiomab as GD2 surrogate for immunotherapy of neuroblastoma.

Holger N. Lode, Manuela Schmidt, Diana Seidel, Nicole Huebener, Diana Brackrock, Matthias Bleeke, Daniel Reker, Sven Brandt, Hans-Peter Mueller, Christiane Helm, Nikolai Siebert
Journal: Cancer Research
Cancer Res (2013) 73 (1_Supplement): A28.
https://doi.org/10.1158/1538-7445.TUMIMM2012-A28
Published: 02 April 2014
View article titled, Abstract A28: Generation and characterization of anti-idiotype antibody ganglidiomab as GD2 surrogate for immunotherapy of neuroblastoma.
Journal Articles

Smac Mimetic LBW242 Sensitizes XIAP-Overexpressing Neuroblastoma Cells for TNF-α–Independent Apoptosis

Georg Eschenburg, Angelika Eggert, Alexander Schramm, Holger N. Lode, Patrick Hundsdoerfer
Journal: Cancer Research
Cancer Res (2012) 72 (10): 2645–2656.
https://doi.org/10.1158/0008-5472.CAN-11-4072
Published: 14 May 2012
View article titled, Smac Mimetic LBW242 Sensitizes XIAP-Overexpressing Neuroblastoma Cells for TNF-α–Independent Apoptosis
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Includes: Supplementary data
Journal Articles

Abstract 1808: Neuroblastoma cell lines established from progressive disease that exhibit partial or multi drug resistance are highly sensitive to chimeric receptor scFv(ch14.18)-zeta mediated NK cell killing

Diana Seidel, Anastasia Shibina, C. Patrick Reynolds, Winfried S. Wels, Holger N. Lode, Nicole Huebener
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1808.
https://doi.org/10.1158/1538-7445.AM2011-1808
Published: 15 April 2011
View article titled, Abstract 1808: Neuroblastoma cell lines established from progressive disease that exhibit partial or multi drug resistance are highly sensitive to chimeric receptor scFv(ch14.18)-zeta mediated NK cell killing
Journal Articles

Abstract 1800: 4-HPR (fenretinide) sensitizes human neuroblastoma cells for antibody-independent and ch14.18-mediated NK cell killing

Anastasia Shibina, Diana Seidel, Srinivas Somanchi, Holger N. Lode, Dean A. Lee, C.Patrick Reynolds, Nicole Huebener
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1800.
https://doi.org/10.1158/1538-7445.AM2011-1800
Published: 15 April 2011
View article titled, Abstract 1800: 4-HPR (fenretinide) sensitizes human neuroblastoma cells for antibody-independent and ch14.18-mediated NK cell killing
Journal Articles

Abstract LB-155: A new syngeneic MYCN-overexpressing neuroblastoma mouse model and MYCN-DNA vaccine

Alexander Stermann, Nicole Huebener, Holger N. Lode
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-155.
https://doi.org/10.1158/1538-7445.AM2011-LB-155
Published: 15 April 2011
View article titled, Abstract LB-155: A new syngeneic MYCN-overexpressing neuroblastoma mouse model and MYCN-DNA vaccine
Journal Articles

Abstract 5601: NK cells engineered to express the chimeric receptor scFv(ch14.18)-zeta specifically lyse GD2 expressing neuroectodermal tumors

Diana Seidel, Nicole Huebener, Tina Mueller, Dörthe Pferdmenges, Anastasia Shibina, Torsten Tonn, Ulrike Koehl, Ruth Esser, Winfried S. Wels, Holger N. Lode
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5601.
https://doi.org/10.1158/1538-7445.AM10-5601
Published: 15 April 2010
View article titled, Abstract 5601: NK cells engineered to express the chimeric receptor scFv(ch14.18)-zeta specifically lyse GD2 expressing neuroectodermal tumors
Journal Articles

Abstract 4758: A new syngeneic MYCN-overexpressing neuroblastoma mouse model and MYCN-DNA vaccine

Alexander Stermann, Nicole Huebener, Diana Seidel, Anastasia Shibina, Stefan Fest, Gerhard Gaedicke, Holger N. Lode
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4758.
https://doi.org/10.1158/1538-7445.AM10-4758
Published: 15 April 2010
View article titled, Abstract 4758: A new syngeneic MYCN-overexpressing neuroblastoma mouse model and MYCN-DNA vaccine
Journal Articles

Abstract 2407: Establishment of a clinically applicable human tyrosine hydroxylase DNA vaccine for anti-neuroblastoma immunotherapy

Anastasia Shibina, Nicole Nuebener, Diana Seidel, Alexander Stermann, Holger N. Lode, Gerhard Gaedicke
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2407.
https://doi.org/10.1158/1538-7445.AM10-2407
Published: 15 April 2010
View article titled, Abstract 2407: Establishment of a clinically applicable human tyrosine hydroxylase DNA vaccine for anti-neuroblastoma immunotherapy
Journal Articles

A novel legumain DNA vaccine effectively eradicates neuroblastoma and induces long-term survival in vivo

Anja Woehler, Nicole Huebener, Stefan Fest, Alexander Stermann, Gerhard Gaedicke, Holger N Lode
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2868.
Published: 01 May 2008
View article titled, A novel legumain DNA vaccine effectively eradicates neuroblastoma and induces long-term survival in vivo
Journal Articles

Fractalkine (CX3CL1)– and Interleukin-2–Enriched Neuroblastoma Microenvironment Induces Eradication of Metastases Mediated by T Cells and Natural Killer Cells

Yan Zeng, Nicole Huebener, Stefan Fest, Silke Weixler, Ulrike Schroeder, Gerhard Gaedicke, Rong Xiang, Alexander Schramm, Angelika Eggert, Ralph A. Reisfeld, Holger N. Lode
Journal: Cancer Research
Cancer Res (2007) 67 (5): 2331–2338.
https://doi.org/10.1158/0008-5472.CAN-06-3041
Published: 01 March 2007
View article titled, Fractalkine (CX3CL1)– and Interleukin-2–Enriched Neuroblastoma Microenvironment Induces Eradication of Metastases Mediated by T Cells and Natural Killer Cells
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Journal Articles

Characterization of GD2 Peptide Mimotope DNA Vaccines Effective against Spontaneous Neuroblastoma Metastases

Stefan Fest, Nicole Huebener, Silke Weixler, Matthias Bleeke, Yan Zeng, Anne Strandsby, Rudolf Volkmer-Engert, Christiane Landgraf, Gerhard Gaedicke, Angelika B. Riemer, Elke Michalsky, Ines S. Jaeger, Robert Preissner, Elisabeth Förster-Wald, Erika Jensen-Jarolim, Holger N. Lode
Journal: Cancer Research
Cancer Res (2006) 66 (21): 10567–10575.
https://doi.org/10.1158/0008-5472.CAN-06-1158
Published: 01 November 2006
View article titled, Characterization of GD2 Peptide Mimotope DNA Vaccines Effective against Spontaneous Neuroblastoma Metastases
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Journal Articles

Peptide mutation analysis results in potent GD2 mimotope peptides for DNA vaccination against neuroblastoma

Holger N. Lode, Mathias Bleeke, Stefan Fest, Nicole Huebener, Yan Zeng, Silke Weixler, Rudolf Volkmer, Elisabeth Förster-Waldl, Erika Jensen-Jarolim, Gerhard Gaedicke
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 332.
Published: 15 April 2006
View article titled, Peptide mutation analysis results in potent GD2 mimotope peptides for DNA vaccination against neuroblastoma
Journal Articles

Vaccination with epitope mimics induces IgG antibodies recognising GD2 in melanoma and neuroblastoma cell extracts

Kira H. Bramswig, Angelika B. Riemer, Elisabeth Förster-Waldl, Arnold Pollak, Christoph C. Zielinski, Hubert Pehamberger, Holger N. Lode, Otto Scheiner, Erika Jensen-Jarolim
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 333.
Published: 15 April 2006
View article titled, Vaccination with epitope mimics induces IgG antibodies recognising GD2 in melanoma and neuroblastoma cell extracts
Journal Articles

Structural and antigenic mimicry of peptides with the 14.18 epitope of neuroblastoma antigen GD2

Kira H. Brämswig, Angelika B. Riemer, Elisabeth Förster-Waldl, Anna Katherina Dehof, Dirk Neumann, Georg Boltz-Nitulescu, Hubert Pehamberger, Christoph Zielinski, Otto Scheiner, Holger N. Lode, Erika Jensen-Jarolim
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 130.
Published: 01 May 2005
View article titled, Structural and antigenic mimicry of peptides with the 14.18 epitope of neuroblastoma antigen GD2
Journal Articles

Targeted Interleukin 2 Therapy Enhances Protective Immunity Induced by an Autologous Oral DNA Vaccine against Murine Melanoma

Andreas G. Niethammer, Rong Xiang, J. Michael Ruehlmann, Holger N. Lode, Carrie S. Dolman, Stephen D. Gillies, Ralph A. Reisfeld
Journal: Cancer Research
Cancer Res (2001) 61 (16): 6178–6184.
Published: 01 August 2001
View article titled, Targeted Interleukin 2 Therapy Enhances Protective Immunity Induced by an Autologous Oral DNA Vaccine against Murine Melanoma
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Journal Articles

Induction of Persistent Tumor-protective Immunity in Mice Cured of Established Colon Carcinoma Metastases

Rong Xiang, Holger N. Lode, Torsten Dreier, Stephen D. Gillies, Ralph A. Reisfeld
Journal: Cancer Research
Cancer Res (1998) 58 (17): 3918–3925.
Published: 01 September 1998
View article titled, Induction of Persistent Tumor-protective Immunity in Mice Cured of Established Colon Carcinoma Metastases
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Journal Articles

Targeted Therapy with a Novel Enediyene Antibiotic Calicheamicin ϑI1 Effectively Suppresses Growth and Dissemination of Liver Metastases in a Syngeneic Model of Murine Neuroblastoma

Holger N. Lode, Ralph A. Reisfeld, Rupert Handgretinger, Kyriacos C. Nicolaou, Gerhard Gaedicke, Wolfgang Wrasidlo
Journal: Cancer Research
Cancer Res (1998) 58 (14): 2925–2928.
Published: 01 July 1998
View article titled, Targeted Therapy with a Novel Enediyene Antibiotic Calicheamicin ϑ<sup>I</sup><sub>1</sub> Effectively Suppresses Growth and Dissemination of Liver Metastases in a Syngeneic Model of Murine Neuroblastoma
Open the PDF for Targeted Therapy with a Novel Enediyene Antibiotic Calicheamicin ϑ<sup>I</sup><sub>1</sub> Effectively Suppresses Growth and Dissemination of Liver Metastases in a Syngeneic Model of Murine Neuroblastoma in another window
Journal Articles

Elimination of Established Murine Colon Carcinoma Metastases by Antibody- Interleukin 2 Fusion Protein Therapy

Rong Xiang, Holger N. Lode, Carrie S. Dolman, Torsten Dreier, Nissi M. Varki, Xiuqi Qian, Kin-Ming Lo, Yan Lan, Michael Super, Stephen D. Gillies, Ralph A. Reisfeld
Journal: Cancer Research
Cancer Res (1997) 57 (21): 4948–4955.
Published: 01 November 1997
View article titled, Elimination of Established Murine Colon Carcinoma Metastases by Antibody- Interleukin 2 Fusion Protein Therapy
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