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Journal Articles

Abstract 2883: HDAC6 mediates the radioresistance of NSCLC through LSD1, independent of its own deacetylation activity

Sojung Ha, Hyejin Kim, Hani Lee, Seokgyeong Choi, Ho-young Lee, Woo-Young Kim

Cancer Res (2024) 84 (6_Supplement): 2883.

https://doi.org/10.1158/1538-7445.AM2024-2883

Published: 22 March 2024

View articletitled, Abstract 2883: HDAC6 mediates the radioresistance of NSCLC through LSD1, independent of its own deacetylation activity

Journal Articles

Abstract 3083: Unveiling the role of chemotherapy-resistant, slow-cycling cancer cells in driving cancer cachexia

Jaebeom Cho, Ho-Young Lee

Cancer Res (2024) 84 (6_Supplement): 3083.

https://doi.org/10.1158/1538-7445.AM2024-3083

Published: 22 March 2024

View articletitled, Abstract 3083: Unveiling the role of chemotherapy-resistant, slow-cycling cancer cells in driving cancer cachexia

Journal Articles

Dual Impact of IGF2 on Alveolar Stem Cell Function during Tobacco-Induced Injury Repair and Development of Pulmonary Emphysema and Cancer

Hye-Jin Boo, Hye-Young Min, Choon-Sik Park, Jong-Sook Park, Ji Yun Jeong, Shin Yup Lee, Woo-Young Kim, Jae-Won Lee, Sei-Ryang Oh, Rang-Woon Park, Ho-Young Lee

Cancer Res (2023) 83 (11): 1782–1799.

https://doi.org/10.1158/0008-5472.CAN-22-3543

Published: 02 June 2023

View articletitled, Dual Impact of IGF2 on Alveolar Stem Cell Function during Tobacco-Induced Injury Repair and Development of Pulmonary Emphysema and Cancer

Includes: Supplementary data

Journal Articles

The Interplay between Slow-Cycling, Chemoresistant Cancer Cells and Fibroblasts Creates a Proinflammatory Niche for Tumor Progression

Jaebeom Cho, Hyo-Jong Lee, Su Jung Hwang, Hye-Young Min, Han Na Kang, A-Young Park, Seung Yeob Hyun, Jeong Yeon Sim, Ho Jin Lee, Hyun-Ji Jang, Young-Ah Suh, Sungyoul Hong, Young Kee Shin, Hye Ryun Kim, Ho-Young Lee

Cancer Res (2020) 80 (11): 2257–2272.

https://doi.org/10.1158/0008-5472.CAN-19-0631

Published: 02 June 2020

View articletitled, The Interplay between Slow-Cycling, Chemoresistant Cancer Cells and Fibroblasts Creates a Proinflammatory Niche for Tumor Progression

Includes: Supplementary data

Journal Articles

Abstract 4806: Development of a novel antitumor agent NCT compound for the treatment of non-small cell lung cancer

Seung Yeob Hyun, Huong Thuy Le, Young-Sik Yong, Hye-Young Min, Jeewoo Lee, Ho-Young Lee

Cancer Res (2019) 79 (13_Supplement): 4806.

https://doi.org/10.1158/1538-7445.AM2019-4806

Published: 01 July 2019

View articletitled, Abstract 4806: Development of a novel antitumor agent NCT compound for the treatment of non-small cell lung cancer

Journal Articles

Abstract 1862: Natural compound E targets both lung cancer stem and non-cancer stem cells by disrupting HSP70 function

Seung Yeob Hyun, Huong Thuy Le, HongLan Pei, Simin Chun, Hye-Young Min, Suckchang Hong, Ho-Young Lee

Cancer Res (2019) 79 (13_Supplement): 1862.

https://doi.org/10.1158/1538-7445.AM2019-1862

Published: 01 July 2019

View articletitled, Abstract 1862: Natural compound E targets both lung cancer stem and non-cancer stem cells by disrupting HSP70 function

Journal Articles

Abstract 2677: A natural product-derived Compound A effectively targets both cancer stem and non-stem cells in NSCLC

Seung Yeob Hyun, Huong T. Le, Jaebeom Cho, Hye-Young Min, Ho-Young Lee

Cancer Res (2018) 78 (13_Supplement): 2677.

https://doi.org/10.1158/1538-7445.AM2018-2677

Published: 01 July 2018

View articletitled, Abstract 2677: A natural product-derived Compound A effectively targets both cancer stem and non-stem cells in NSCLC

Journal Articles

Abstract 2950: Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity

Ho-Jin Lee, Hye-Young Min, Phuong Chi Pham, Byungyeob Baek, Byungjin Kim, Yunha Kim, Jeeyeon Lee, Ho-Young Lee

Cancer Res (2018) 78 (13_Supplement): 2950.

https://doi.org/10.1158/1538-7445.AM2018-2950

Published: 01 July 2018

View articletitled, Abstract 2950: Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity

Journal Articles

SPON2 Promotes M1-like Macrophage Recruitment and Inhibits Hepatocellular Carcinoma Metastasis by Distinct Integrin–Rho GTPase–Hippo Pathways

Yan-Li Zhang, Qing Li, Xiao-Mei Yang, Fang Fang, Jun Li, Ya-Hui Wang, Qin Yang, Lei Zhu, Hui-Zhen Nie, Xue-Li Zhang, Ming-Xuan Feng, Shu-Heng Jiang, Guang-Ang Tian, Li-Peng Hu, Ho-Young Lee, Su-Jae Lee, Qiang Xia, Zhi-Gang Zhang

Cancer Res (2018) 78 (9): 2305–2317.

https://doi.org/10.1158/0008-5472.CAN-17-2867

Published: 30 April 2018

View articletitled, SPON2 Promotes M1-like Macrophage Recruitment and Inhibits Hepatocellular Carcinoma Metastasis by Distinct Integrin–Rho GTPase–Hippo Pathways

Includes: Supplementary data

Journal Articles

Abstract 3188: ER-stress induced translational regulation by RGS2 leads to tumor-promoting microenvironment and chemoresistance

Hye-Young Min, Shin-Hyung Park, Ho Jin Lee, Jaebeom Cho, Myungkyung Noh, Seung Yeob Hyun, Ho-Young Lee

Cancer Res (2017) 77 (13_Supplement): 3188.

https://doi.org/10.1158/1538-7445.AM2017-3188

Published: 01 July 2017

View articletitled, Abstract 3188: ER-stress induced translational regulation by RGS2 leads to tumor-promoting microenvironment and chemoresistance

Journal Articles

Abstract 4780: Crucial role of S100A14 in blocking cancer stem cells and sensitizing to chemotherapy through STAT3 destabilization in human colorectal cancer

Jaebeom Cho, Hye-Young Min, Ji-Sun Lee, Ho-Young Lee

Cancer Res (2017) 77 (13_Supplement): 4780.

https://doi.org/10.1158/1538-7445.AM2017-4780

Published: 01 July 2017

View articletitled, Abstract 4780: Crucial role of S100A14 in blocking cancer stem cells and sensitizing to chemotherapy through STAT3 destabilization in human colorectal cancer

Journal Articles

Abstract 3553: Mutant KRas-mediated AKT2 activation supports lung cancer growth by activating complex II-driven mitochondrial metabolism

Kwan-Hee Park, Ho-Young Lee

Cancer Res (2017) 77 (13_Supplement): 3553.

https://doi.org/10.1158/1538-7445.AM2017-3553

Published: 01 July 2017

View articletitled, Abstract 3553: Mutant KRas-mediated AKT2 activation supports lung cancer growth by activating complex II-driven mitochondrial metabolism

Journal Articles

Chronic Stress Facilitates Lung Tumorigenesis by Promoting Exocytosis of IGF2 in Lung Epithelial Cells

Hyun-Ji Jang, Hye-Jin Boo, Ho Jin Lee, Hye-Young Min, Ho-Young Lee

Cancer Res (2016) 76 (22): 6607–6619.

https://doi.org/10.1158/0008-5472.CAN-16-0990

Published: 14 November 2016

View articletitled, Chronic Stress Facilitates Lung Tumorigenesis by Promoting Exocytosis of IGF2 in Lung Epithelial Cells

Includes: Supplementary data

Journal Articles

Abstract A36: Resistance to IGF-1R targeted therapy by insulin-like growth factor 2-mediated tumor microenvironment network

Ji-Sun Lee, Ho-Young Lee

Cancer Res (2016) 76 (15_Supplement): A36.

https://doi.org/10.1158/1538-7445.TME16-A36

Published: 28 July 2016

View articletitled, Abstract A36: Resistance to IGF-1R targeted therapy by insulin-like growth factor 2-mediated tumor microenvironment network

Journal Articles

Abstract 4931: Validation of Trastuzumab immunohistochemistry as a predictive and prognostic biomarker in gastric cancer patients

Jiwon Koh, Soo Kyung Nam, Younwoo Lee, Chan-Young Ock, Jin Won Kim, Keun-Wook Lee, Do-Youn Oh, Do Joong Park, Hyung-Ho Kim, Keon-Wook Kang, Woo Ho Kim, Ho-Young Lee, Hye Seung Lee

Cancer Res (2016) 76 (14_Supplement): 4931.

https://doi.org/10.1158/1538-7445.AM2016-4931

Published: 15 July 2016

View articletitled, Abstract 4931: Validation of Trastuzumab immunohistochemistry as a predictive and prognostic biomarker in gastric cancer patients

Journal Articles

Deguelin Analogue SH-1242 Inhibits Hsp90 Activity and Exerts Potent Anticancer Efficacy with Limited Neurotoxicity

Cancer Res (2016) 76 (3): 686–699.

https://doi.org/10.1158/0008-5472.CAN-15-1492

Published: 31 January 2016

View articletitled, Deguelin Analogue SH-1242 Inhibits Hsp90 Activity and Exerts Potent Anticancer Efficacy with Limited Neurotoxicity

Includes: Supplementary data

Journal Articles

Abstract 2711: Regulation of the IGF-1R signaling by angiotensin signaling pathway

Hye-Jin Boo, Hyun-Ji Jang, Yujin Jung, Hye-Young Min, Ho-Young Lee

Cancer Res (2015) 75 (15_Supplement): 2711.

https://doi.org/10.1158/1538-7445.AM2015-2711

Published: 01 August 2015

View articletitled, Abstract 2711: Regulation of the IGF-1R signaling by angiotensin signaling pathway

Journal Articles

Abstract 2729: Chronic stress promotes lung cancer development via IGF-1R pathway

Hyun-Ji Jang, Hye-Jin Boo, Yujin Jung, Hye-Young Min, Ho-Young Lee

Cancer Res (2015) 75 (15_Supplement): 2729.

https://doi.org/10.1158/1538-7445.AM2015-2729

Published: 01 August 2015

View articletitled, Abstract 2729: Chronic stress promotes lung cancer development via IGF-1R pathway

Journal Articles

Abstract 1716: Targeting the insulin-like growth factor receptor/Insulin receptor and Src signaling network for the treatment of non-small cell lung cancer

Hye-Young Min, Hye Jeong Yun, Hyo-Jong Lee, Jaebeom Cho, Hyun-Ji Jang, Kyung Min Kim, Woo-Young Kim, Seung-Hyun Oh, Diane Liu, J. Jack Lee, Waun K. Hong, Ignacio I. Wistuba, Ho-Young Lee

Cancer Res (2014) 74 (19_Supplement): 1716.

https://doi.org/10.1158/1538-7445.AM2014-1716

Published: 01 October 2014

View articletitled, Abstract 1716: Targeting the insulin-like growth factor receptor/Insulin receptor and Src signaling network for the treatment of non-small cell lung cancer

Journal Articles

Abstract 3196: Antitumor effect of a Compound A, a derivative of a naturally occurring rotenoid deguelin, by inhibition of ATP binding to heat shock protein 90

Su-Chan Lee, Ju-Sung Lee, Seung-Yeob Hyun, Hoon Choi, Hongchan An, Kyu-Won Kim, Young-Ger Suh, Ho-Young Lee

Cancer Res (2014) 74 (19_Supplement): 3196.

https://doi.org/10.1158/1538-7445.AM2014-3196

Published: 01 October 2014

View articletitled, Abstract 3196: Antitumor effect of a Compound A, a derivative of a naturally occurring rotenoid deguelin, by inhibition of ATP binding to heat shock protein 90

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Abstract 2883: HDAC6 mediates the radioresistance of NSCLC through LSD1, independent of its own deacetylation activity

Abstract 3083: Unveiling the role of chemotherapy-resistant, slow-cycling cancer cells in driving cancer cachexia

Dual Impact of IGF2 on Alveolar Stem Cell Function during Tobacco-Induced Injury Repair and Development of Pulmonary Emphysema and Cancer

The Interplay between Slow-Cycling, Chemoresistant Cancer Cells and Fibroblasts Creates a Proinflammatory Niche for Tumor Progression

Abstract 4806: Development of a novel antitumor agent NCT compound for the treatment of non-small cell lung cancer

Abstract 1862: Natural compound E targets both lung cancer stem and non-cancer stem cells by disrupting HSP70 function

Abstract 2677: A natural product-derived Compound A effectively targets both cancer stem and non-stem cells in NSCLC

Abstract 2950: Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity

SPON2 Promotes M1-like Macrophage Recruitment and Inhibits Hepatocellular Carcinoma Metastasis by Distinct Integrin–Rho GTPase–Hippo Pathways

Abstract 3188: ER-stress induced translational regulation by RGS2 leads to tumor-promoting microenvironment and chemoresistance

Abstract 4780: Crucial role of S100A14 in blocking cancer stem cells and sensitizing to chemotherapy through STAT3 destabilization in human colorectal cancer

Abstract 3553: Mutant KRas-mediated AKT2 activation supports lung cancer growth by activating complex II-driven mitochondrial metabolism

Chronic Stress Facilitates Lung Tumorigenesis by Promoting Exocytosis of IGF2 in Lung Epithelial Cells

Abstract A36: Resistance to IGF-1R targeted therapy by insulin-like growth factor 2-mediated tumor microenvironment network

Abstract 4931: Validation of Trastuzumab immunohistochemistry as a predictive and prognostic biomarker in gastric cancer patients

Deguelin Analogue SH-1242 Inhibits Hsp90 Activity and Exerts Potent Anticancer Efficacy with Limited Neurotoxicity

Abstract 2711: Regulation of the IGF-1R signaling by angiotensin signaling pathway

Abstract 2729: Chronic stress promotes lung cancer development via IGF-1R pathway

Abstract 1716: Targeting the insulin-like growth factor receptor/Insulin receptor and Src signaling network for the treatment of non-small cell lung cancer

Abstract 3196: Antitumor effect of a Compound A, a derivative of a naturally occurring rotenoid deguelin, by inhibition of ATP binding to heat shock protein 90

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