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Hisataka Kobayashi
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Journal Articles

Abstract 5971: F3 targeted near-infrared photoimmunotherapy: The ideal therapeutic approach for numerous malignancies

Seiichiro Takao, Aki Furusawa, Hiroshi Fukushima, Shuhei Okuyama, Makoto Kano, Hiroshi Yamamoto, Peter L. Choyke, Hisataka Kobayashi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5971.
https://doi.org/10.1158/1538-7445.AM2024-5971
Published: 22 March 2024
View article titled, Abstract 5971: F3 targeted near-infrared photoimmunotherapy: The ideal therapeutic approach for numerous malignancies
Journal Articles

Abstract 5110: Locally administered Interleukin-15 combined with cancer cell-targeted near-infrared photoimmunotherapy in a syngeneic mouse cancer model

Hiroshi Fukushima, Aki Furusawa, Takuya Kato, Seiichiro Takao, Shuhei Okuyama, Peter L. Choyke, Hisataka Kobayashi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5110.
https://doi.org/10.1158/1538-7445.AM2023-5110
Published: 04 April 2023
View article titled, Abstract 5110: Locally administered Interleukin-15 combined with cancer cell-targeted near-infrared photoimmunotherapy in a syngeneic mouse cancer model
Journal Articles

Abstract 696: Phototheranostics of epithelioid sarcoma by targeting CD44 or EGFR

Jiefu Jin, James Barnett, Yelena Mironchik, Hisataka Kobayashi, Adam Levin, Zaver M. Bhujwalla
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 696.
https://doi.org/10.1158/1538-7445.AM2021-696
Published: 01 July 2021
View article titled, Abstract 696: Phototheranostics of epithelioid sarcoma by targeting CD44 or EGFR
Journal Articles

Rapid Depletion of Intratumoral Regulatory T Cells Induces Synchronized CD8 T- and NK-cell Activation and IFNγ-Dependent Tumor Vessel Regression

Yutaka Kurebayashi, Colleen P. Olkowski, Kelly C. Lane, Olga V. Vasalatiy, Biying C. Xu, Ryuhei Okada, Aki Furusawa, Peter L. Choyke, Hisataka Kobayashi, Noriko Sato
Journal: Cancer Research
Cancer Res (2021) 81 (11): 3092–3104.
https://doi.org/10.1158/0008-5472.CAN-20-2673
Published: 01 June 2021
View article titled, Rapid Depletion of Intratumoral Regulatory T Cells Induces Synchronized CD8 T- and NK-cell Activation and IFNγ-Dependent Tumor Vessel Regression
Open the PDF for Rapid Depletion of Intratumoral Regulatory T Cells Induces Synchronized CD8 T- and NK-cell Activation and IFNγ-Dependent Tumor Vessel Regression in another window
Includes: Supplementary data
Journal Articles

Abstract 3360: Phototheranostics of cancer associated fibroblasts by targeting fibroblast activation protein-α

Jiefu Jin, James D. Barnett, Balaji Krishnamachary, Yelena Mironchik, Hisataka Kobayashi, Zaver Bhujwalla
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3360.
https://doi.org/10.1158/1538-7445.AM2020-3360
Published: 15 August 2020
View article titled, Abstract 3360: Phototheranostics of cancer associated fibroblasts by targeting fibroblast activation protein-α
Journal Articles

Abstract 3444: Intratumor regulatory T cells prevent IFN-gamma-dependent tumor vessel regression and can be selectively targeted by anti-CD25 near-infrared photoimmunotherapy

Yutaka Kurebayashi, Peter L. Choyke, Hisataka Kobayashi, Noriko Sato
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3444.
https://doi.org/10.1158/1538-7445.AM2020-3444
Published: 15 August 2020
View article titled, Abstract 3444: Intratumor regulatory T cells prevent IFN-gamma-dependent tumor vessel regression and can be selectively targeted by anti-CD25 near-infrared photoimmunotherapy
Journal Articles

Abstract 3206: Host immunity following near infrared photoimmunotherapy is enhanced with PD-1 checkpoint blockade to eradicate established highly antigenic tumors

Tadanobu Nagaya, Jay Friedman, Yasuhiro Maruoka, Fusa Ogata, Shuhei Okuyama, Paul E. Clavijo, Peter L. Choyke, Clint Allen, Hisataka Kobayashi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3206.
https://doi.org/10.1158/1538-7445.AM2019-3206
Published: 01 July 2019
View article titled, Abstract 3206: Host immunity following near infrared photoimmunotherapy is enhanced with PD-1 checkpoint blockade to eradicate established highly antigenic tumors
Journal Articles

Abstract 3831: Development of near-infrared photoimmunotherapy targeting GD2-positive neuroblastoma

Hiroshi Nouso, Hiroshi Tazawa, Terutaka Tanimoto, Morimichi Tani, Takanori Oyama, Hiroaki Sato, Kazuhiro Noma, Shunsuke Kagawa, Hisataka Kobayashi, Takuo Noda, Toshiyoshi Fujiwara
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3831.
https://doi.org/10.1158/1538-7445.AM2018-3831
Published: 01 July 2018
View article titled, Abstract 3831: Development of near-infrared photoimmunotherapy targeting GD2-positive neuroblastoma
Journal Articles

Abstract 5066: Dual-targeting photoimmunotherapy (NIR-PIT) for esophageal cancer cells and cancer-associated fibroblasts (CAFs)

Hiroaki Sato, Kazuhiro Noma, Toru Narusaka, Satoshi Komoto, Yuki Katsura, Takuya Kato, Takayuki Ninomiya, Toshiaki Ohara, Hiroshi Tazawa, Yasuhiro Shirakawa, Hisataka Kobayashi, Toshiyoshi Fujiwara
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5066.
https://doi.org/10.1158/1538-7445.AM2018-5066
Published: 01 July 2018
View article titled, Abstract 5066: Dual-targeting photoimmunotherapy (NIR-PIT) for esophageal cancer cells and cancer-associated fibroblasts (CAFs)
Journal Articles

Abstract 1470: Cancer treatment by near infrared photoimmunotherapy targeting intratumoral regulatory T cells

Kazuhide Sato, Noriko Sato, Biying Xu, Yuko Nakamura, Tadanobu Nagaya, Peter L. Choyke, Hisataka Kobayashi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1470.
https://doi.org/10.1158/1538-7445.AM2016-1470
Published: 15 July 2016
View article titled, Abstract 1470: Cancer treatment by near infrared photoimmunotherapy targeting intratumoral regulatory T cells
Journal Articles

Abstract 2019: Photoimmunotherapy with an anti-EGFR antibody conjugated to an IRDye700 results in extensive and rapid cell death in vitro and in vivo in human pancreatic cancer cell lines

Nzola de Magalhães, Takashi Murakami, Roger Heim, Lew Makings, Miguel Garcia-Guzman, Hisataka Kobayashi, Robert M. Hoffman, Michael Bouvet
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2019.
https://doi.org/10.1158/1538-7445.AM2015-2019
Published: 01 August 2015
View article titled, Abstract 2019: Photoimmunotherapy with an anti-EGFR antibody conjugated to an IRDye700 results in extensive and rapid cell death in vitro and in vivo in human pancreatic cancer cell lines
Journal Articles

Abstract 2484: IR700-conjugated anti-CD44 monoclonal antibody for phototherapy theranostics of triple-negative breast cancer

Jiefu Jin, Balaji Krishnamachary, Hisataka Kobayashi, Zaver Bhujwalla
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2484.
https://doi.org/10.1158/1538-7445.AM2015-2484
Published: 01 August 2015
View article titled, Abstract 2484: IR700-conjugated anti-CD44 monoclonal antibody for phototherapy theranostics of triple-negative breast cancer
Journal Articles

Abstract 401: A novel photoimmunotherapy targeting cancer-associated fibroblasts (CAFs) overcomes therapeutic resistance in human esophageal cancer

Ryoichi Katsube, Kazuhiro Noma, Shinichiro Watanabe, Shinichi Urano, Takayuki Ninomiya, Toshiaki Ohara, Hiroshi Tazawa, Shunsuke Kagawa, Hisataka Kobayashi, Toshiyoshi Fujiwara
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 401.
https://doi.org/10.1158/1538-7445.AM2015-401
Published: 01 August 2015
View article titled, Abstract 401: A novel photoimmunotherapy targeting cancer-associated fibroblasts (CAFs) overcomes therapeutic resistance in human esophageal cancer
Journal Articles

Abstract 4118: Near infrared photoimmunotherapy for lung metastases

Kazuhide Sato, Tadanobu Nagaya, Peter L. Choyke, Hisataka Kobayashi
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4118.
https://doi.org/10.1158/1538-7445.AM2015-4118
Published: 01 August 2015
View article titled, Abstract 4118: Near infrared photoimmunotherapy for lung metastases
Journal Articles

Abstract 3311: Molecular targeted photoimmunotherapy as a treatment for bladder cancer

Reema Railkar, Quentin Li, Srinivas Vourganti, Sam J. Brancato, Peter L. Choyke, Hisataka Kobayashi, Piyush K. Agarwal
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3311.
https://doi.org/10.1158/1538-7445.AM2015-3311
Published: 01 August 2015
View article titled, Abstract 3311: Molecular targeted photoimmunotherapy as a treatment for bladder cancer
Journal Articles

Abstract 2615: Novel combination therapy of adenoviral gene transfer of HER2-extracellular domain and trastuzumab-based photoimmunotherapy for HER2 negative cancer cells

Michihiro Ishida, Shunsuke Kagawa, Kyoko Shimoyama, Kiyoto Takehara, Kazuhiro Noma, Shunsuke Tanabe, Hiroshi Tazawa, Junji Matsuoka, Hisataka Kobayashi, Toshiyoshi Fujiwara
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2615.
https://doi.org/10.1158/1538-7445.AM2014-2615
Published: 01 October 2014
View article titled, Abstract 2615: Novel combination therapy of adenoviral gene transfer of HER2-extracellular domain and trastuzumab-based photoimmunotherapy for HER2 negative cancer cells
Journal Articles

Abstract 5400: Photoimmunotherapy (PIT) combined with a nanosized cancer agent successfully treated heterogenous antigen-expressing tumors based on super-enhanced permeability and retention (SUPR) effect

Hisataka Kobayashi, Kohei Sano, Takahito Nakajima, Kazuhide Sato, Peter L. Choyke
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5400.
https://doi.org/10.1158/1538-7445.AM2014-5400
Published: 01 October 2014
View article titled, Abstract 5400: Photoimmunotherapy (PIT) combined with a nanosized cancer agent successfully treated heterogenous antigen-expressing tumors based on super-enhanced permeability and retention (SUPR) effect
Journal Articles

Abstract 4512: Super-enhanced permeability and retention (SUPR) effect induced by photo-immunotherapy (PIT) can accommodate massive nano-sized reagents deep into tumors.

Hisataka Kobayashi, Kohei Sano, Takahito Nakajima, Peter L. Choyke
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4512.
https://doi.org/10.1158/1538-7445.AM2013-4512
Published: 15 April 2013
View article titled, Abstract 4512: Super-enhanced permeability and retention (SUPR) effect induced by photo-immunotherapy (PIT) can accommodate massive nano-sized reagents deep into tumors.
Journal Articles

Abstract 3298: Neotargeting HER2 negative cancer cells with Trastuzumab-based photoimmunotherapy by viral transduction of HER2-extracellular domain.

Michihiro Ishida, Shunsuke Kagawa, Kyoko Shimoyama, Shinichiro Watamabe, Kazuhiro Noma, Hiroshi Tazawa, Yuuri Hashimoto, Junji Matsuoka, Hisataka Kobayashi, Toshiyoshi Fujiwara
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3298.
https://doi.org/10.1158/1538-7445.AM2013-3298
Published: 15 April 2013
View article titled, Abstract 3298: Neotargeting HER2 negative cancer cells with Trastuzumab-based photoimmunotherapy by viral transduction of HER2-extracellular domain.
Journal Articles

Real-time Monitoring of In Vivo Acute Necrotic Cancer Cell Death Induced by Near Infrared Photoimmunotherapy Using Fluorescence Lifetime Imaging

Takahito Nakajima, Kohei Sano, Makoto Mitsunaga, Peter L. Choyke, Hisataka Kobayashi
Journal: Cancer Research
Cancer Res (2012) 72 (18): 4622–4628.
https://doi.org/10.1158/0008-5472.CAN-12-1298
Published: 16 September 2012
View article titled, Real-time Monitoring of <em>In Vivo</em> Acute Necrotic Cancer Cell Death Induced by Near Infrared Photoimmunotherapy Using Fluorescence Lifetime Imaging
Open the PDF for Real-time Monitoring of <em>In Vivo</em> Acute Necrotic Cancer Cell Death Induced by Near Infrared Photoimmunotherapy Using Fluorescence Lifetime Imaging in another window
Includes: Supplementary data