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Hiroyuki Kobayashi
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Journal Articles

Abstract 6222: Comprehensive monitoring of pyruvate metabolism in cancer cells and tumors reveals vulnerability to metabolic inhibition therapy with small molecules

Free
Nobu Oshima, Yuki Aisu, Shigeo Hisamori, Shigeru Tsunoda, Hiroki Hashida, Kenji Uryuhara, Hiroyuki Kobayashi, Masato Kondo, koji Kitamura, Satoshi Kaihara, Kazutaka Obama, Krishna Murali, Len Neckers
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6222.
https://doi.org/10.1158/1538-7445.AM2022-6222
Published: 15 June 2022
View articletitled, Abstract 6222: Comprehensive monitoring of pyruvate metabolism in cancer cells and tumors reveals vulnerability to metabolic inhibition therapy with small molecules
Journal Articles

Abstract LB187: EGFR signaling and pharmacology in oncology revealed with an innovative RTK biosensor technology

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Florence Gross, Guilhem Dugast, Arturo Mancini, Hiroyuki Kobayashi, Michel Bouvier, Stephan Schann, Xavier Leroy, Laurent Sabbagh
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB187.
https://doi.org/10.1158/1538-7445.AM2021-LB187
Published: 01 July 2021
View articletitled, Abstract LB187: EGFR signaling and pharmacology in oncology revealed with an innovative RTK biosensor technology
Journal Articles

Deletion of the INK4a/Arf gene locus prevents dephosphorylation of p42/p44-MAPK in response to the EGFR inhibitor tyrphostin AG1478 in primary mouse astrocytes and mouse glioma cell lines.

Free
Yan Lachat, Annie-Claire Diserens, Michimasa Nozaki, Hiroyuki Kobayashi, Marie-France Hamou, Nicolas De Tribolet, Monika E. Hegi
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 697.
Published: 01 April 2004
View articletitled, Deletion of the INK4a/Arf gene locus prevents dephosphorylation of p42/p44-MAPK in response to the EGFR inhibitor tyrphostin AG1478 in primary mouse astrocytes and mouse glioma cell lines.
Journal Articles

Classification of Human Astrocytic Gliomas on the Basis of Gene Expression: A Correlated Group of Genes with Angiogenic Activity Emerges As a Strong Predictor of Subtypes

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Sophie Godard, Gad Getz, Mauro Delorenzi, Pierre Farmer, Hiroyuki Kobayashi, Isabelle Desbaillets, Michimasa Nozaki, Annie-Claire Diserens, Marie-France Hamou, Pierre-Yves Dietrich, Luca Regli, Robert C. Janzer, Philipp Bucher, Roger Stupp, Nicolas de Tribolet, Eytan Domany, Monika E. Hegi
Journal: Cancer Research
Cancer Res (2003) 63 (20): 6613–6625.
Published: 28 October 2003
View articletitled, Classification of Human Astrocytic Gliomas on the Basis of Gene Expression: A Correlated Group of Genes with Angiogenic Activity Emerges As a Strong Predictor of Subtypes
Open the PDF for Classification of Human Astrocytic Gliomas on the Basis of Gene Expression: A Correlated Group of Genes with Angiogenic Activity Emerges As a Strong Predictor of Subtypes in another window
Includes: Supplementary data
Journal Articles

Altered Pharmacokinetics of a Novel Anticancer Drug, UCN-01, Caused by Specific High Affinity Binding to α1-Acid Glycoprotein in Humans

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Eiichi Fuse, Hiromi Tanii, Katsumi Takai, Kazuki Asanome, Noriaki Kurata, Hiroyuki Kobayashi, Takashi Kuwabara, Satoshi Kobayashi, Yuichi Sugiyama
Journal: Cancer Research
Cancer Res (1999) 59 (5): 1054–1060.
Published: 01 March 1999
View articletitled, Altered Pharmacokinetics of a Novel Anticancer Drug, UCN-01, Caused by Specific High Affinity Binding to α1-Acid Glycoprotein in Humans
Open the PDF for Altered Pharmacokinetics of a Novel Anticancer Drug, UCN-01, Caused by Specific High Affinity Binding to α1-Acid Glycoprotein in Humans in another window
Journal Articles

Unpredicted Clinical Pharmacology of UCN-01 Caused by Specific Binding to Human α1-Acid Glycoprotein

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Eiichi Fuse, Hiromi Tanii, Noriaki Kurata, Hiroyuki Kobayashi, Yasuhiro Shimada, Tomohide Tamura, Yasutsuna Sasaki, Yusuke Tanigawara, Richard D. Lush, Donna Headlee, William D. Figg, Susan G. Arbuck, Adrian M. Senderowicz, Edward A. Sausville, Shiro Akinaga, Takashi Kuwabara, Satoshi Kobayashi
Journal: Cancer Research
Cancer Res (1998) 58 (15): 3248–3253.
Published: 01 August 1998
View articletitled, Unpredicted Clinical Pharmacology of UCN-01 Caused by Specific Binding to Human α1-Acid Glycoprotein
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Journal Articles

Reversal of Drug Sensitivity in Multidrug-Resistant Tumor Cells by an MDR1 (PGY1) Ribozyme

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Hiroyuki Kobayashi, Thambi Dorai, James F. Holland, Takao Ohnuma
Journal: Cancer Research
Cancer Res (1994) 54 (5): 1271–1275.
Published: 01 March 1994
View articletitled, Reversal of Drug Sensitivity in Multidrug-Resistant Tumor Cells by an MDR1 (PGY1) Ribozyme
Open the PDF for Reversal of Drug Sensitivity in Multidrug-Resistant Tumor Cells by an MDR1 (PGY1) Ribozyme in another window