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Hiroyasu Esumi
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Journal Articles

Abstract 3932: Metabolic biomarkers predict the sensitivity to phosphatidylinositol 3-kinase pathway inhibitor in small-cell lung carcinoma

Free
Shigeki Umemura, Hideki Makinoshima, Genichiro Ishii, Takehiko Sasaki, Hiroyasu Esumi, Koichi Goto, Katsuya Tsuchihara
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3932.
https://doi.org/10.1158/1538-7445.AM2018-3932
Published: 01 July 2018
View articletitled, Abstract 3932: Metabolic biomarkers predict the sensitivity to phosphatidylinositol 3-kinase pathway inhibitor in small-cell lung carcinoma
Journal Articles

Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma

Free
Hideki Makinoshima, Shigeki Umemura, Ayako Suzuki, Hiroki Nakanishi, Ami Maruyama, Hibiki Udagawa, Sachiyo Mimaki, Shingo Matsumoto, Seiji Niho, Genichiro Ishii, Masahiro Tsuboi, Atsushi Ochiai, Hiroyasu Esumi, Takehiko Sasaki, Koichi Goto, Katsuya Tsuchihara
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (9): 2179–2190.
https://doi.org/10.1158/0008-5472.CAN-17-2109
Published: 30 April 2018
View articletitled, Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma
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Includes: Supplementary data
Journal Articles

Abstract CT213: Arctigenin, an antiausterity agent shows high safety and promising clinical response in phase I clinical trial in patient with gemcitabine-refractory pancreatic cancer

Free
Hiroyasu Esumi, Satoshi Owada, Rumi Fujioka, Katsuya Tsuchihara, Atsushi Ohtsu, Aihiro Sato, Masafumi Ikeda, Nobuo Mochizuki, Satoshi Kishino, Takanori Kawashima, Satoshi Yomoda
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): CT213.
https://doi.org/10.1158/1538-7445.AM2014-CT213
Published: 01 October 2014
View articletitled, Abstract CT213: Arctigenin, an antiausterity agent shows high safety and promising clinical response in phase I clinical trial in patient with gemcitabine-refractory pancreatic cancer
Journal Articles

Abstract 3361: EGFR signaling regulates aerobic glycolysis in EGFR-mutated lung adenocarcinoma

Free
Hideki Makinoshima, Masahiro Takita, Shingo Matsumoto, Atsushi Yagishita, Satoshi Owada, Hiroyasu Esumi, Katsuya Tsuchihara
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3361.
https://doi.org/10.1158/1538-7445.AM2014-3361
Published: 01 October 2014
View articletitled, Abstract 3361: EGFR signaling regulates aerobic glycolysis in EGFR-mutated lung adenocarcinoma
Journal Articles

Abstract 2208: Detection of somatic mutations and gene amplifications using amplicon sequencing with biopsy samples from patients with advanced gastric cancer

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Wataru Okamoto, Takeshi Kuwata, Shingo Matsumoto, Yoichi Naito, Hideaki Takahashi, Kohei Shitara, Yasutoshi Kuboki, Hideaki Bando, Yoko Yamada, Izumi Miki, Takeharu Yamanaka, Atsushi Ohtsu, Atsushi Ochiai, Hiroyasu Esumi, Takayuki Yoshino, Katsuya Tsuchihara
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2208.
https://doi.org/10.1158/1538-7445.AM2014-2208
Published: 01 October 2014
View articletitled, Abstract 2208: Detection of somatic mutations and gene amplifications using amplicon sequencing with biopsy samples from patients with advanced gastric cancer
Journal Articles

Abstract 5134: The identification and characterization of genetic variations in lung adenocarcinomas in a Japanese population

Free
Sachiyo Mimaki, Ayako Suzuki, Koutatsu Matsushima, Makito Suzuki, Naomi Ogasawara, Yutaka Suzuki, Katsuya Tsuchihara, Hiroyasu Esumi
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5134.
https://doi.org/10.1158/1538-7445.AM2012-5134
Published: 15 April 2012
View articletitled, Abstract 5134: The identification and characterization of genetic variations in lung adenocarcinomas in a Japanese population
Journal Articles

Abstract 1133: Glucose deprivation-induced intracellular reactive oxygen species activates the PI3K-AKT axis

Free
Satoshi Owada, Yuko Shimoda, Katsuya Tsuchihara, Hiroyasu Esumi
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1133.
https://doi.org/10.1158/1538-7445.AM2012-1133
Published: 15 April 2012
View articletitled, Abstract 1133: Glucose deprivation-induced intracellular reactive oxygen species activates the PI3K-AKT axis
Journal Articles

Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry

Free
Akiyoshi Hirayama, Kenjiro Kami, Masahiro Sugimoto, Maki Sugawara, Naoko Toki, Hiroko Onozuka, Taira Kinoshita, Norio Saito, Atsushi Ochiai, Masaru Tomita, Hiroyasu Esumi, Tomoyoshi Soga
Journal: Cancer Research
Cancer Res (2009) 69 (11): 4918–4925.
https://doi.org/10.1158/0008-5472.CAN-08-4806
Published: 01 June 2009
View articletitled, Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry
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Includes: Supplementary data
Journal Articles

Abstract #3419: Reduced tumor susceptibility and improved metabolic disorders by voluntary exercise in Snark-deficient mice

Free
Katsuya Tsuchihara, Rumi Fujioka, Hiroyasu Esumi
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3419.
Published: 01 May 2009
View articletitled, Abstract #3419: Reduced tumor susceptibility and improved metabolic disorders by voluntary exercise in Snark-deficient mice
Journal Articles

ARK5 regulates the growth of HTLV-1-infected T cells during glucose starvation

Free
Mariko Tomita, Shuhei Taniguchi, Atsushi Suzuki, Tetsuro Nakazato, Chie Ishikawa, Taeko Okudaira, Hiroyasu Esumi, Naoki Mori
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 599.
Published: 01 May 2008
View articletitled, ARK5 regulates the growth of HTLV-1-infected T cells during glucose starvation
Journal Articles

Autophagy Is Activated in Colorectal Cancer Cells and Contributes to the Tolerance to Nutrient Deprivation

Free
Kazunori Sato, Katsuya Tsuchihara, Satoshi Fujii, Masanori Sugiyama, Tomoyuki Goya, Yutaka Atomi, Takashi Ueno, Atsushi Ochiai, Hiroyasu Esumi
Journal: Cancer Research
Cancer Res (2007) 67 (20): 9677–9684.
https://doi.org/10.1158/0008-5472.CAN-07-1462
Published: 17 October 2007
View articletitled, Autophagy Is Activated in Colorectal Cancer Cells and Contributes to the Tolerance to Nutrient Deprivation
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Includes: Supplementary data
Journal Articles

Identification of Arctigenin as an Antitumor Agent Having the Ability to Eliminate the Tolerance of Cancer Cells to Nutrient Starvation

Free
Suresh Awale, Jie Lu, Surya K. Kalauni, Yukiko Kurashima, Yasuhiro Tezuka, Shigetoshi Kadota, Hiroyasu Esumi
Journal: Cancer Research
Cancer Res (2006) 66 (3): 1751–1757.
https://doi.org/10.1158/0008-5472.CAN-05-3143
Published: 01 February 2006
View articletitled, Identification of Arctigenin as an Antitumor Agent Having the Ability to Eliminate the Tolerance of Cancer Cells to Nutrient Starvation
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Journal Articles

Overexpression of c-Maf Contributes to T-Cell Lymphoma in Both Mice and Human

Free
Naoki Morito, Keigyou Yoh, Yuki Fujioka, Takako Nakano, Homare Shimohata, Yuko Hashimoto, Akiko Yamada, Atsuko Maeda, Fumihiko Matsuno, Hiroyuki Hata, Atsushi Suzuki, Shigehiko Imagawa, Hiroaki Mitsuya, Hiroyasu Esumi, Akio Koyama, Masayuki Yamamoto, Naoyoshi Mori, Satoru Takahashi
Journal: Cancer Research
Cancer Res (2006) 66 (2): 812–819.
https://doi.org/10.1158/0008-5472.CAN-05-2154
Published: 19 January 2006
View articletitled, Overexpression of c-Maf Contributes to T-Cell Lymphoma in Both Mice and Human
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Journal Articles

Chemopreventive Effect of Peroxisome Proliferator–Activated Receptor γ on Gastric Carcinogenesis in Mice

Free
Jie Lu, Kazuhiro Imamura, Sachiyo Nomura, Ken-ichi Mafune, Atsushi Nakajima, Takashi Kadowaki, Naoto Kubota, Yasuo Terauchi, Genichiro Ishii, Atsushi Ochiai, Hiroyasu Esumi, Michio Kaminishi
Journal: Cancer Research
Cancer Res (2005) 65 (11): 4769–4774.
https://doi.org/10.1158/0008-5472.CAN-04-2293
Published: 01 June 2005
View articletitled, Chemopreventive Effect of Peroxisome Proliferator–Activated Receptor γ on Gastric Carcinogenesis in Mice
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Journal Articles

Remarkable Tolerance of Tumor Cells to Nutrient Deprivation: Possible New Biochemical Target for Cancer Therapy

Free
Kunihiko Izuishi, Kazuyoshi Kato, Tsutomu Ogura, Taira Kinoshita, Hiroyasu Esumi
Journal: Cancer Research
Cancer Res (2000) 60 (21): 6201–6207.
Published: 01 November 2000
View articletitled, Remarkable Tolerance of Tumor Cells to Nutrient Deprivation: Possible New Biochemical Target for Cancer Therapy
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Journal Articles

Instability of X Chromosome Methylation in Aberrant Crypt Foci of the Human Colon

Free
Nobuyuki Sakurazawa, Noritake Tanaka, Masahiko Onda, Hiroyasu Esumi
Journal: Cancer Research
Cancer Res (2000) 60 (12): 3165–3169.
Published: 15 June 2000
View articletitled, Instability of X Chromosome Methylation in Aberrant Crypt Foci of the Human Colon
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Journal Articles

Mutagenic Activation of Environmental Carcinogens by Microsomes of Gastric Mucosa with Intestinal Metaplasia

Free
Masayuki Tatemichi, Sachiyo Nomura, Tsutomu Ogura, Hideko Sone, Hiroshi Nagata, Hiroyasu Esumi
Journal: Cancer Research
Cancer Res (1999) 59 (16): 3893–3898.
Published: 15 August 1999
View articletitled, Mutagenic Activation of Environmental Carcinogens by Microsomes of Gastric Mucosa with Intestinal Metaplasia
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Journal Articles

Emergence of Adenomatous Aberrant Crypt Foci (ACF) from Hyperplastic ACF with Concomitant Increase in Cell Proliferation

Free
Kazuhiko Otori, Kenji Sugiyama, Takahiro Hasebe, Shoji Fukushima, Hiroyasu Esumi
Journal: Cancer Research
Cancer Res (1995) 55 (21): 4743–4746.
Published: 01 November 1995
View articletitled, Emergence of Adenomatous Aberrant Crypt Foci (ACF) from Hyperplastic ACF with Concomitant Increase in Cell Proliferation
Open the PDF for Emergence of Adenomatous Aberrant Crypt Foci (ACF) from Hyperplastic ACF with Concomitant Increase in Cell Proliferation in another window
Journal Articles

Infrequent K-ras Activation in Superficial-Type (Flat) Colorectal Adenomas and Adenocarcinomas

Free
Toshinari Minamoto, Kiyoshi Sawaguchi, Masayoshi Mai, Naoyuki Yamashita, Takashi Sugimura, Hiroyasu Esumi
Journal: Cancer Research
Cancer Res (1994) 54 (11): 2841–2844.
Published: 01 June 1994
View articletitled, Infrequent K-ras Activation in Superficial-Type (Flat) Colorectal Adenomas and Adenocarcinomas
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Journal Articles

U.S.-Japan Cooperative Cancer Research Program: Seminar on Nitric Oxide Synthase and Cardnogenesis

Free
Hiroyasu Esumi, Steven R. Tennenbaum
Journal: Cancer Research
Cancer Res (1994) 54 (1): 297–301.
Published: 01 January 1994
View articletitled, U.S.-Japan Cooperative Cancer Research Program: Seminar on Nitric Oxide Synthase and Cardnogenesis
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